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Journal : NurseLine Journal

The Effect of Hemodialysis on Kinetic Segment of Left Ventricular in Stage V Chronic Kidney Diseases Patients Systriana Esi Kamasita; Suryono Suryono; Yudha Nurdian; Yuli Hermansyah; Edy Junaidi; Mohamat Fatekurohman
NurseLine Journal Vol 3 No 1 (2018): May 2018
Publisher : Faculty of Nursing, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v3i1.6506

Abstract

Chronic kidney disease (CKD) stage V attacks other organs such as heart that can cause cardiovascular disease (CVD). One of them is CVD caused by CKD stage V that is the kinetic segment of left ventricle. Cardiovascular disease occurs due to excess fluid and buildup of uremic toxin. Chronic kidney disease stage V can not be cured so it requires therapy that is hemodialysis (HD). Hemodialysis can reduce excess fluid, uremic toxin, and maintain electrolyte balance in stage V stage. Improved fluid and decreased uremic toxin can reduce the burden of the heart and strain so that blood supply to certain myocardial areas increases and the left ventricular kinetic segment increases. The purpose of this study is to determine the effect of HD on left ventricular kinetic changes in CKD stage V patients in dr. Soebandi hospital in Jember. The research design used was quasi-experimental one group pretest-postest design. The sample was 30 patients. Respondents were determined by nonprobability sampling technique with purposive sampling method. The data used are primary data and secondary data. Data analysis using Wilcoxon test. Based on the results of the study, the distribution of the sample based on the age of the most in the range of 45-54 years, based on the sex obtained more women, based on the duration of hemodialysis obtained the period of most hemodialysis> 24 months and based on blood pressure before and after hemodialysis obtained patients with hypertension. Hypothesis test using Wilcoxon test got p-value (0.000). From the results of the analysis can be concluded that there is influence of hemodialysis on kinetic segment of left ventricle in patient of CKD stage V in dr. Soebandi hospital in Jember.
The Effect of Moringa oleifera (Lam) Leaf Extracts on Growth of Chicken Embryo Induced by Alkohol Indah Kusuma Wardani; Suryono Suryono
NurseLine Journal Vol 4 No 1 (2019): May 2019
Publisher : Faculty of Nursing, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v4i1.11278

Abstract

Fetal Alcohol Syndrome (FAS) is a condition associated with drinking alcohol during pregnancy and affect embryo development. FAS is the most common congenital disabilities in the world. The effects of FAS are mental retardation, cranial abnormalities, and heart defects. Moringa oleifera is a highly valued plant. It has an impressive range of biological activities, including antioxidant, antiproliferation, and anti-inflammatory. This study aims to assess the effect of Moringa oleifera leaf extracts in inhibiting growth retardation of chicken embryo growth induced by alcohol. The study was a true experimental design with posttest controlled group design. There were five groups with 5 of chicken embryo each group. The treatments contained 15% alcohol and aquadest as positive control (P+), without alcohol as negative control (P-), P0.5 (0,5g/dl), P5 (5g/dl), P50 (50g/dl) by adding Moringa oleifera leaf extracts, respectively. Moringa oleifera leaf extracts showed the improvement of length and head diameter as a benchmark for chicken embryo development with P5 concentration showed the best results to overcome growth retardation in alcohol-induced chicken embryos. This finding implies against possibility Moringa oleifera leaf extracts can be alternative medicine to prevent growth retardation.
Renoprotective Activity of Morinaga Oleifera Lamk Toward Kidney Injury Rats Induced by Streptozotocin Giovani Gianosa; Suryono Suryono; Ali Santosa
NurseLine Journal Vol 7 No 1 (2022): May 2022
Publisher : Faculty of Nursing, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v7i1.22116

Abstract

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormalities in insulin secretion. Chronic hyperglycemia in diabetes causes dysfunction and failure of various organs of the body such as the kidneys, eyes, nerves, heart and blood vessels. The purpose of this study was to analyze how the effect of the treatment given by Moringa leaves on diabetes mellitus conditions, especially on glomerular histopathological damage. In this study, to make diabetic mice using the induction of streptozotocin after which Moringa leaves were given as a form of treatment. The dosage of Moringa leaf extract was divided into 5 groups, namely 62.5mg / kg, 125mg / kg, 250mg / kg, 500mg / kg, and 1000mg / kg doses. The histopathological image obtained will be assessed using scoring, and for data analysis using the Kruskal-Wallis test and followed by the post hoc test using the Mann-Whitney test. The results of this study indicate that there is an effect of giving Moringa leaf extract on glomerular histopathological damage. The results of the Kruskal-Wallis data analysis test showed significant results, namely p = 0.001, after the data obtained were significant data, then it was continued with the post hoc test using the Mann-Whitney test with significant results when compared with negative controls ranging from the 125mg / kg dose group 1000mg / kg.