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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Jurnal Kesehatan Lingkungan indonesia Jurnal Ilmu Dasar e-Journal Pustaka Kesehatan Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Indonesian Journal of Tropical and Infectious Disease JITRO (Jurnal Ilmiah dan Teknologi Peternakan Tropis) Journal of Agromedicine and Medical Sciences Journal Of Vocational Health Studies NurseLine Journal Dinamisia: Jurnal Pengabdian Kepada Masyarakat JCES (Journal of Character Education Society) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Medik Veteriner Jurnal Kreativitas PKM Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) Majalah Biomorfologi (Biomorphology Journal) Lumbung Inovasi: Jurnal Pengabdian Kepada Masyarakat Jurnal Abdimas Indonesia : Jurnal Abdimas Indonesia Nursing and Health Sciences Journal (NHSJ) Jurnal Ilmu Sosial dan Humaniora Journal of Health, Education, Economics, Science, and Technology (J-HEST) IPTEK: Jurnal Hasil Pengabdian kepada Masyarakat Dedication : Jurnal Pengabdian Masyarakat InSTEM
Yudha Nurdian
Departemen Parasitologi, Fakultas Kedokteran Universitas Jember, Jember 68121
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Efek Hepatoprotektif Ekstrak Etanol Brokoli (Brassica oleracea L. var. italica) terhadap Kadar Malondialdehid Hepar Tikus Wistar yang Diinduksi DMBA (Hepatoprotective Effect of Ethanolic Extract of Broccoli (Brassica oleracea L. var. italica) on Liver Ma Dear Farah Sielma; Elly Nurus Sakinah; Yudha Nurdian
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

DMBA (7,12-Dimethylbenz(α)antracene) is a prototype of Polycyclic Aromatic Hydrocarbons (PAHs) which is present in automobile exhaust, cigarette smoke, and wood stoves. DMBA is converted into its reactive metabolites DMBA-DE and cause liver cell membrane lipid peroxidation, which results in an increased of liver malondialdehyde (MDA) levels. Broccoli contains flavonoid that able to prevent lipid peroxidation. The current study was conducted to find out the different hepatoprotective effect of ethanolic extract of broccoli against DMBA-induced hepatotoxicity in wistar rats using liver MDA as a marker. A total of 24 male wistar rats were divided into six groups, consisting of normal control (distilled water), negative control (DMBA), and treatment (ethanolic extract of broccoli in doses of 250, 500, 1000, and 2000 mg/kgBW). Rats were treated for 7 days prior to a single dose of DMBA on the 8th day of treatment. Liver tissue samples were taken on the 12th day for measurement of liver MDA levels. Data were analyzed using One Way ANOVA followed by Post Hoc Test LSD. The present study showed significant differences on liver MDA levels between groups (p<0.001). This study concluded that there were different hepatoprotective effects of ethanolic extract of broccoli treatment on liver MDA levels in wistar rats induced by DMBA. Keywords: ethanolic extract of broccoli, DMBA, malondialdehyde, hepatoprotective
Efek Analgesik Kombinasi Kurkumin dan Parasetamol pada Mencit yang Diinduksi Asam Asetat menggunakan Isobologram (The Analgesic Effect of Combination of Curcumin and Paracetamol in Acetic acid-induced Mice using Isobolograms) Nugroho Priyo Utomo; Cicih Komariah; Yudha Nurdian
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Paracetamol is a drug that classified as NSAID and commonly used as analgesic agent. These drugs have toxic effects that lead to liver damage. This effects caused by accumulation the metabolite compound of paracetamol, N-acetyl-p-benzoquinone (NAPQI), by cytochrome P450 enzyme. Some studies reported that curcumin have analgesic effects and inhibit action of cytochrome P450 enzyme. The purpose of this study was to determine the analgesic effect of curcumin and paracetamol combination in 27 acetic-acid induced mice. The result of this study showed that 2358,815 µg of curcumin and paracetamol combination can inhibit pain up to 50%. This result is smaller than paracetamol that need 4200 µg to achieve the same pain inhibition. One Way Annova test showed siginificant difference between paracetamol group and combination group. Isobolographic analysis results showed curcumin and paracetamol have synergistic properties in mice acetic-acid induced pain. Keywords: curcumin, paracetamol, isobolograph
Pengaruh Pemberian Ekstrak Etanol Brokoli (Brassica oleracea) terhadap Kadar SGOT dan SGPT Tikus Wistar yang Diinduksi DMBA (The Effect of Ethanolic Extract of Broccoli (Brassica oleracea) on SGOT and SGPT of Wistar Rats Induced by DMBA) Rizka Nuzula Wardani; Elly Nurus Sakinah; Yudha Nurdian
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

DMBA is a product of incomplete burning which can cause free radicals in human. The metabolism of DMBA by Cytochrome P450 in liver causes hepatocyte DNA damage and decrease endogenous antioxidant. Broccoli contains flavonoid which can act as an antioxidant by inhibiting formation of free radicals through hydrogen atom donation to free radicals. This research aimed to analyze the effect of ethanolic extract of broccoli on SGOT and SGPT of wistar rats induced by DMBA. This research used 24 rats divided into six groups: control group, negative control group, and four treatment groups with broccoli ethanolic extract of 250 mg/kgBW, 500 mg/kgBW, 1000 mg/kgBW, and 2000 mg/kgBW for 7 days. The SGOT and SGPT levels of control group were 70,36 U/L and 33,97 U/L; negative control group 107,16 U/L and 56,21 U/L; the first treatment 101,50 U/L and 49,33 U/L; the second treatment 85,32 U/L and 43,67 U/L; the third treatment 84,11 U/L and 40,84 U/L; and the fourth treatment 81,28 U/L and 35,18 U/L. The result of One Way Annova test for SGOT was p=0,012 while SGPT was p=0,003. In this study, ethanolic extract of broccoli could protect hepatocyte by decreasing SGOT and SGPT levels.   Keywords: ethanolic extract of broccoli, SGOT and SGPT levels, DMBA
Hubungan perilaku hidup bersih dan sehat dengan kejadian infestasi Soil–transmitted Helminths pada pekerja perkebunan kopi Sumber Wadung Kabupaten Jember Ahmad Hasbi Al-Muzaky; Bagus Hermansyah; Enny Suswati; Yunita Armiyanti; Yudha Nurdian
JURNAL KEDOKTERAN DAN KESEHATAN Vol 6, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (293.379 KB) | DOI: 10.32539/JKK.v6i1.7233

Abstract

Infestasi Soil - Transmitted Helminths (STH) merupakan masalah kesehatan yang masih sering ditemukan di negara beriklim tropis, salah satunya di Indonesia. Hal ini dikarenakan perkembangan STH membutuhkan kondisi lingkungan yang hangat dan lembab, serta  memerlukan media tanah untuk menjadi fase infektif yang disebut soil - transmitted helminth.Kondisi ini dapat ditemukan di lingkungan perkebunan yang sangat menguntungkan bagi perkembangan STH. Hal ini menyebabkan para pekerja perkebunan sangat beresiko terinfestasi oleh STH. Tujuan penelitian ini adalah mengetahui adanya hubungan perilaku hidup bersih dan sehat (PHBS) dengan kejadian infestasi STH pada pekerja perkebunan kopi. Jenis penelitian ini adalah penelitian analisis deskriptif dengan desain cross-sectional yang dilaksanakan pada bulan Desember 2018 hingga Januari 2019. Perkebunan yang dipilih adalah Perkebunan Kopi Sumber Wadung di Kabupaten Jember dengan jumlah sampel sebanyak 100 orang responden dan diberikan kuisioer PHBS. Pemeriksaan infestasi STH dilakukan dengan dua metode yaitu flotasi dan sedimentasi. Dari 100 responden, 28 pekerja (28%) terinfestasi oleh STH. Kemudian dilakukan uji analisis chi-square antara PHBS dengan kejadian infestasi STH dan didapatkan adanya hubungan antara PHBS dengan kejadian infestasi STH pada pekerja (<0,05).
Correlation between Cholinesterase Levels and Blood Glucose Levels in Farmers Exposed to Organophosphate Pesticide in Desa Sukorambi Kabupaten Jember Sofiannisa Achmadila; Kristianningrum Dian Sofiana; Yudha Nurdian
Journal of Agromedicine and Medical Sciences Vol 5 No 3 (2019)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v5i3.9652

Abstract

The use of organophosphate pesticides by farmers can cause long-term health risks, one of which is an increase in blood glucose levels. This study aims to determine whether there is a relationship between the levels of cholinesterase as an indicator of exposure to organophosphate pesticides and blood glucose of farmers in Sukorambi Village, Jember Regency. Secondary data in the form of general characteristics of the sample were obtained through interviews, while the primary data was obtained from examining the levels of cholinesterase and blood glucose levels of farmers at the Biochemical Laboratory of the Faculty of Medicine, Jember University. The research method is observational-analytic with cross-sectional study design. Based on the results of statistical analysis using the Spearman correlation test (p = 0.05), it was concluded that there was no significant relationship between the two variables (p = 0.0802).
Type 3 Resistant Starch Effect of Cassava (Manihot esculenta Crantz) on Fasting Blood Glucose in Diabetes Mellitus Wistar Rat Models T Ariani Widiastini; Elly Nurus Sakinah; Yudha Nurdian; Jauhar Firdaus
Journal of Agromedicine and Medical Sciences Vol 4 No 3 (2018)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v4i3.6469

Abstract

Type 2 Diabetes Mellitus (T2DM) is a condition in which both insulin secretion and insulin sentivity disturbed. One of therapeutic approach of T2DM is through diet modification using resistant starch (RS) that has proven controlling both postprandial and fasting blood glucose. Cassava starch has 28,57% amylose and 51,24% amylopectin that can be increased through autoclaving-cooling process. Therefore, it can resist the digestion proess by amylose enzyme. The aim was to describe the effect of type 3 resistant starch cassava (Manihot esculenta Crantz) on fasting blood glucose (FBG) in Wistar diabetic rat models. This study was quasy experimental post-test only control group design using 16 Wistar rats divided into 4 groups, KN (normal), K- (DM), P1 (DM + cassava starch diet), and P2 (DM + type 3 RS cassava diet). High fat diet (HFD) and low dose streptozotocin (STZ) used as diabetic agents. Rats fed cassava starch or type 3 RS cassava diet for 28 days. GOD-PAP method used to measure the FBG level. The data analyzed using One Way ANOVA test with p>0,05 as significant value. The result shows no significant differences within experimental groups. Keywords: cassava, autoclaving-cooling, resistant starch, FBG
Risk Factors Affecting Carpal Tunnel Syndrome in Women Laborer of Tobacco Warehouse Ajung District, Jember Dasarina Rizqi Amalia; Ida Srisurani Wiji Astuti; Yudha Nurdian
Journal of Agromedicine and Medical Sciences Vol 5 No 2 (2019)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v5i2.6489

Abstract

Carpal Tunnel Syndrome frequently experienced by workers whose daily activities always use repetitive movements on the wrist. Carpal Tunnel Syndrome is a syndrome that can actually be prevented because there is no risk factor that can’t be changed except the age factor. Previous research has shown a fairly high prevalence about 42%-93% in factory workers. This study aims to determine the factors that affect the occurence of Carpal Tunnel Syndrome in women workers warehouse tobacco. This is an analytical observational study with cross sectional study design which using 50 samples who met inclusion and exclusion criteria. Instrument in this research is clinical questionnaire to diagnose CTS and Phalen test. Spearman correlation test result obtained long working p=0,036, r=0,298 and pain intensity p= <0,01, r=0,635 which means there is significant correlation with moderate strength between length of work with CTS and strong correlation between the intensity of pain with CTS. Keywords: Carpal Tunnel Syndrome, risk factor, women laborer
Association between Personal Hygiene and Incidence of Soil-Transmitted Helminthiasis among Workers at Widodaren Plantation in Jember Regency Zulaikha Rizqina Rahmawati; Bagus Hermansyah; Erfan Efendi; Yunita Armiyanti; Yudha Nurdian; Wiwien Sugih Utami
Journal of Agromedicine and Medical Sciences Vol 6 No 1 (2020)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v6i1.9593

Abstract

Soil-Transmitted Helmithiasis is an infection caused by intestinal nematode worms which in the process of transmission requires soil as media to fullfil its life cycle from non-infective forms to infective forms. The number of infections is influenced by personal hygiene. Personal hygiene consists of the habit of washing hands, cutting nails, eating, defecating and ownership of latrines, and the use of personal protective equipment. This study used a cross sectional research design conducted at Widodaren Plantation with 68 people of samples. Stool examination was determined by kato-katz method, sedimentation, and floatation to detect the presence of Soil-Transmitted Helminth (STH) eggs, while personal hygiene was assessed using questionnaires. Questionnaire and stool examination datas were processed using SPSS data analysis with chi-square method. The results of this study found 26 respondents who were positive for soil-trasmitted helminthiasis infection. The most frequent worm species obtained in this study were Ascaris lumbricoides (57.7%), followed by multiple infections between Hookworm and A. lumbricoides (21.3%), and Hookworm (19.2%). In the chi-square analysis the results were significant between personal hygiene and soil-transmitted helminthiasis with p value of 0,000 (p <0.05). So, it can be concluded that a bad personal hygiene factor has a significant relationship to the incidence of Soil-Transmitted Helminthiasis at Widodaren Plantation. Keywords: Personal hygiene, STH, plantation
Aedes aegypti Mosquito Potential Larvacidal of Phyllantus niruri L. Leaves Ethanol Extracts Moh. Lutfi Hasbullah; Yudha Nurdian; Cholis Abrori
Journal of Agromedicine and Medical Sciences Vol 5 No 1 (2019)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v5i1.6775

Abstract

Dengue hemorrhagic fever (DHF) is a disease caused by dengue virus transmitted by Aedes aegyptifemale mosquitoes with four major clinical manifestations, such as high fever, hemorrhage,hepatomegaly, and signs of circulatory failure. Indonesia was reported as the 2nd country with thelargest dengue cases among 30 endemic countries. The larvicidal powder is used as one of thedengue virus vector controllers. This study aims to determine the effect of ethanol extract of smallgooseberry leaves (Phyllantus niruri L.) to the death of Aedes aegypti mosquitoes. This study usedquasi experimental method with post test only controlled group design with 1 positive control group(Temephos), 1 group of negative control (tap water), and 5 treatment groups (0.0625%, 0.125%,0.25% , 0.5% and 1% extract) used 20 larvaes of Aedes aegypti instar III each group. The results of thetreatment group extract with a concentration of 0.5% and 1% obtained 100% dead larvae. The resultof linear regression test showed the effect of meniran leaf extract on the death of larvae Ae. aegyptiwith R2 value of 65.2%. The larvacid activity of ethanol extract leaves meniran against larvae Ae.aegypti instar III was directly proportional to concentration with LC50 of 0.174% with 95% confidenceinterval (0.155-0.195).
The Use of Saturated MgSO4 Compared to Saturated Sucrose in the Flotation Method to Identify Eggs and Larvae of Soil-Transmitted Helminths from Plantation Soil Nidya Husna Kholidah; Yunita Armiyanti; Dwita Aryadina Rachmawati; Bagus Hermansyah; Yudha Nurdian
Journal of Agromedicine and Medical Sciences Vol 7 No 2 (2021)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v7i2.17093

Abstract

Worms infection is still common in Indonesia with a prevalence that varies around 40% -60% at all ages. This disease can be caused by infection of Soil-Transmitted Helminths (STH) that require soil media to infect humans. The many plantation lands in Jember are a suitable environment for the development of STH and STH identification in soil can be done by flotation method using MgSO4 solution or sucrose. The comparison of the effectiveness of the MgSO4 solution with the sucrose solution has not been widely studied. Therefore, the aim of this study was to compare the efficacy of using saturated MgSO4 solution with saturated sucrose to identify eggs and larvae of STH in Sumber Wadung plantation soil, Hargomulyo Village, Silo District, Jember Regency using the flotation method. Soil samples were taken as many as 35 samples in the garden area, 35 samples around the river, and 35 samples in residential areas,. The results of identification of STH eggs and larvae obtained Ascarid eggs (1.9%) and Hookworm larvae (0.01%). The number of positive soil samples containing STH eggs and larvae using different solutions is the same as three samples (0.02%).The Wilcoxon test results showed that there was no difference in the results of using the MgSO4 solution with the sucrose solution in the flotation method (p> 0.05) so that the MgSO4 solution and sucrose solution could be used to detect eggs and larvae of STH worms and had the same effectiveness. Keyword: Soil-transmitted helminths, saturated MgSO4, saturated sucrose, flotation
Co-Authors . Suryono Abiyu, Nizar Arkana Adhyasta Yuda Adrianto Adilah Julinar Irianti Aditya Faradina Salsabilla Ahmad Ashidhiqie Pramana Ahmad Hasbi Al-Muzaky Akmal Fikri Setiaji Al-Hasany, Elang Avinindra Virgiananta Ali, Alya Maulidya Alif Mardijana Angga Mardro Raharjo Anis Fila Klaudia Ardani, Dhea Febrian Asmara, Chrisnandito Bagus Atik Kurniawati Aulifia Rahmawati Aurellia, Naurah Septa Azharra, Alifiah Zalika Aziz, Ayu Munawaroh Bagus Hermansyah Bayda Masayu Subiyanto Belia Selva Wulan Septyana Cholis Abrori, Cholis Cicih Komariah Cicih Komariyah Cinta Kharisma Sunarto Dasarina Rizqi Amalia Dear Farah Sielma Deriel Thio Miratmaka Desi Dwi Cahyani Dhea Elfitra Noza Dian Ayu Puspayanti Dian Firtana Putri Diana Chusna Mufida Dina Helianti Dini Agustina Drajad, Rahadinda Mutia Dhamar Dwi Mutia Hassny Dwita Aryadina Rachmawati Dyah Kirana Arianti Nugroho Edy Junaidi Elly Nurus Sakinah, Elly Nurus ENNY SUSWATI Erfan Efendi Erica Septafanny Eva Tyas Utami Fabiyyanza, Ralief Yusrial Falah, Pilar Menara Fandika Firman Wijaksana Farradhita Ambar Tauriestya FATIMATUS ZAHROH Fidelina, Salma Aisyawa Fitra Ayu Mardani Fitriyah, Ainun Nadiratul Gensen Brianda Rusoneri Hadziqi, Ilham Fahmi Haq, Hanifah S Hendi Rengga Akhsani Hidayatullah, Ferdi Hilda Pramesti Arminata Santoso Ida Srisurani Wiji Astuti Indi Jasmine Nurhaliza Intani, Rini Nur Irawan Fajar Kusuma Irfan Maulana Ivan Iqbal Baidowi Jauhar Firdaus Kania Rahma Meneling Kautsar, Azyumardi Azra Kristianningrum Dian Sofiana Kusuma, Ancah Caesarina Lanang Nashrullah Lelono, Asmoro M. Ali Shodikin Maria Teliana Sum Maulana, Muhammad Naufal Maulidya Dwi Nuraini Mita Prilla Devie Moh. Lutfi Hasbullah Mohamat Fatekurohman Mufida, Diana C Muhammad Faris Al Ghofiqi Muhammad Irfan Ardiansyah Muhammad Yongki Ivan Sugesta Nabil Reza Maulana Nadia Rahmawati Nafila Syahrani Nariswari, Asti Syahda Nashirudin Al Azizi Naurah Septa Aurellia Nidya Husna Kholidah Ningsih, Sinar Hariati Nisa Urrosidah Novando Aji Baskoro Novinka Sinta Isnainiyah Nuardiansyah, Fahreza Adam Nugraha, Reiza Fajar Nugroho Priyo Utomo Nur Annisa Wahdah Nur Asyia Alfiyani One Farida Arilasmi Peni, Lis Widodo Pinsensius Andreas Prameswari, Dinda Putri Primadana, Aditya Putra, Dwi Rizky Ardi Radiah Ulil Absari Radifan Fahrul Akhyar Rahardjo, Angga Mardro Raharjo, Angga M Rahmadhan, Adiz Dwiputra Rahman, Naisya Anindya Ramadhani, Rafindra Rangga Bayu Satriya Rani Rhiana Putri Rayhana, Intan Muliawati Regita Oktavia Adi Ningsih Relang Rizky Mulyadi Reza Nur Aulia Rezza Putri Mahartika Risang Hadi Wasesa Rizka Nuzula Wardani Rizkiana Rasman Rizqi Fitria Damayanti Rumastika, Nindya Shinta Rutsiana Dessyanti Ndoen Setyaningtias, Siva Putri Silvia Putri Aurelia Siti Hamidah Sofiannisa Achmadila Suhendro, Joshua Revival Supangat Supangat Syahputri, Siti Ananda Hardita Syahrul Aprilia Fallah Al Aziz Syavira Ainur Rohma Systriana Esi Kamasita T Ariani Widiastini Tajriyan, Aynani Tri Mul Yono Tusiana Putri Nelumbium Wardhono, Pradipta Pawitradyaka Wicaksono, Arif Dwi Wicaksono, Muhammad Iqbal Allun Widya Lestari Wijaya, Rizky Surya Wiwien Sugih Utami Yani Corvianindya Rahayu Yoga Samudra Hendarta Yuli Hermansyah Yunita Armiyanti Zahrah Febianti Zulaikha Rizqina Rahmawati