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Masatake Niwa
Faculty of Pharmacy, Meijo University, Tempaku
Chemical Engineering, Chemistry & Bioengineering Chemistry

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BALANOCARPOL AND AMPELOPSIN H, TWO OLIGORESVERATROLS FROM STEM BARK OF Hopea odorata (DIPTEROCARPACEAE) Sri Atun; Nurfina Aznam; Retno Arianingrum; Masatake Niwa
Indonesian Journal of Chemistry Vol 6, No 3 (2006)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.912 KB) | DOI: 10.22146/ijc.21737

Abstract

Two oligoresveratrol, namely balanocarpol (2) and ampelopsin H (3) had been isolated from the steam bark of Hopea odorata (Dipterocarpaceae). The structures of these compounds were elucidated based on physical and spectroscopic data (MS, 1H and 13C NMR 1D and 2D). The activity of these compounds was evaluated against the 2-deoxyribose degradation induced by the hydroxyl radical generated via a Fenton-type reaction. The result showed that activity each compounds as radical hydroxyl scavenger of balanocarpol, and ampelopsin H with an IC50 1802.3 and 4840.0 μg/mL, respectively. Each compound showed low activity. Vitamin C (IC50 83.9 μg/mL) and butylated hydroxyl toluene (1328.0 μg/mL) were used as positif controls. These results suggest that oligoresveratrols from stem bark of H. odorata may be useful as potential sources of natural antioxidants.
BALANOCARPOL AND HEIMIOL A, TWO RESVERATROLS DIMER FROM STEM BARK Hopea mengarawan (Dipterocarpaceae) Sri Atun; Nurfina Aznam; Retno Arianingrum; Masatake Niwa
Indonesian Journal of Chemistry Vol 6, No 1 (2006)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.408 KB) | DOI: 10.22146/ijc.21777

Abstract

Isolation and structure elucidation of two resveratrols dimer, namely balanocarpol (1) and heimiol A (2) from stem bark of Hopea mengarawan had been done. The isolation of those compounds was carried out by chromatographic method and structure elucidation was performed by interpretation of spectroscopic data, including UV, IR,  1H and 13C NMR 1D and 2D, and FABMS.
Co-Authors Nurfina Aznam Retno Arianingrum SRI ATUN