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All Journal Jurnal Kedokteran Diponegoro Journal of Biomedicine and Translational Research Sari Pediatri Paediatrica Indonesiana Jurnal Sehat Indonesia (JUSINDO)
Adhie Nur Radityo Suswihardhyono
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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PENGARUH PEMBERIAN LEAFLET DAN PENJELASAN TERHADAP PENGETAHUAN IBU MENGENAI HIPERBILIRUBINEMIA NEONATORUM Belia Dwi Hapsari Nugraheni; Adhie Nur Radityo Suswihardhyono
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 5, No 2 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.149 KB) | DOI: 10.14710/dmj.v5i2.11569

Abstract

Background : Hyperbilirubinemia is one of the most common clinical phenomenon found in neonates marked yellow coloration of the skin, mucosa, sclera result of the accumulation of direct and indirect bilirubin in serum or blood, if levels reach 5-7mg / dL and could have an impact on infant mortality if handling less. However, mothers' knowledge of hyperbilirubinemia is still low. So it takes a method of counseling to increase knowledge of mothers about hyperbilirubinemia.Aim : Analyzing the effect of leaflets and an explanation of the mothers knowledge regarding neonatal hyperbilirubinemia.Method : This study used a quasi-experimental with pretest posttest group. Samples taken counsecutive sampling. There are 35 subjects of mothers who gave birth at the Hospital dr. Kariadi, Semarang from May to June 2015. The researchers gave questionnaires that have been tested for validity as a pretest and then the subject was given a leaflet and explanations after pretest done. Posttest conducted one day after the subjects were counseled on neonatal hyperbilirubinemia. All result were analyzed using the Wilcoxon test..Result : This study, the mean maternal age 29.97 ± 7.09 years and the majority of respondents are housewives amounted to 48.60%. Knowledge mean of 5.82 ± 4.68 before being given a leaflet and explanations, can be increased significantly to 14 ± 2.99 at posttest, after being given leaflets and explanations with a value of p <0.05.Conclusion : Methods of individual counseling with the help of leaflets can increase knowledge about the mother neonatal hyperbilirubinemia.
Faktor yang Berhubungan dengan Kenaikan Berat Badan Bayi Berat Lahir Rendah Daffa Hafizh Afian; Mohamad Syarofil Anam; Ari Budi Himawan; Adhie Nur Radityo Suswihardhyono
Sari Pediatri Vol 23, No 2 (2021)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp23.2.2021.75-81

Abstract

Latar belakang. Bayi berat lahir rendah (BBLR) memiliki risiko morbiditas, keterlambatan pertumbuhan dan gagal tumbuh. Faktor yang berhubungan kenaikan berat badan BBLR perlu diketahui agar risiko keterlambatan pertumbuhan dapat dikendalikan. Tujuan. Menganalisis faktor-faktor yang berhubungan dengan kenaikan berat badan BBLR di RSUD R.A. Kartini Jepara.Metode. Penelitian ini merupakan studi kasus kontrol. Subyek dibagi dalam kelompok kasus (BBLR dengan kenaikan berat badan tidak sesuai grafik Fenton) dan kelompok kontrol (BBLR dengan kenaikan berat badan sesuai grafik Fenton), kemudian secara retrospektif diteliti faktor yang berhubungan dengan kenaikan BB selama 4 minggu pemantauan. Faktor-faktor yang diteliti adalah usia kehamilan, berat lahir, komplikasi, jumlah diit dan pemberian nutrisi parenteral.Hasil. Data dipilih secara consecutive sampling, didapatkan 148 subyek penelitian yang terdiri dari 72 kasus dan 76 kontrol. Didapatkan 36,1% laki-laki pada kelompok kasus dan 60,5% pada kelompok kontrol. Hubungan bermakna ditemukan pada kenaikan berat badan pada BBLR dengan jenis kelamin (p=0,003), berat lahir (p=0,01), usia kehamilan (p=0,035), komplikasi (p=0,037) dan jumlah diit minggu kedua (p<0,001). Namun, tidak terdapat hubungan bermakna antara kenaikan berat badan pada BBLR dengan pemberian nutrisi parenteral (p=0,093).Kesimpulan. Usia kehamilan, berat lahir, komplikasi dan jumlah diit berhubungan dengan kenaikan berat badan BBLR.
Risk factors contributing to weaning failure from continuous positive airway pressure to high flow nasal cannula in neonates with respiratory distress syndrome Putra, Najih Rama Eka; Dadiyanto, Dwi Wastoro; Sahyuni, Riza; Rini, Arsita Eka; Muryawan, Heru; Suswihardhyono, Adhie Nur Radityo
Paediatrica Indonesiana Vol. 64 No. 1 (2024): January 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.1.2024.77-85

Abstract

Background Respiratory distress syndrome (RDS) is one of the most frequent causes of mortality and morbidity in neonates. High flow nasal canule (HFNC) is a step ladder modality of alternative oxygen therapy for weaning to reduce the workload of breathing and the need for intubation. Objective To identify the risk factors contributing to weaning failure from continuous positive airway pressure (CPAP) to HFNC in neonates with RDS. Methods This study was a retrospective observational study in neonates aged less than 36 weeks weighing less than 2500 grams who underwent CPAP to HFNC weaning from 2019 to 2021 in Dr. Kariadi Hospital, Semarang, Central Java, Indonesia. Results There were 108 patients included in this study. Our bivariate analysis found significant differences in gestational age, age at the start of weaning, body weight at the start of weaning, FiO2 levels, history of maternal chorioamnionitis, patent ductus arteriosus (PDA), anemia, apnea of prematurity (AOP), and sepsis in neonates with RDS. Multivariate analysis showed that the most dominant factors were FiO2 levels of more than 25% at the start of weaning (OR11.16; 95%CI 1.83 to 63.12; P=0.009), anemia (OR 7.70; 95%CI 1.39 to 42.67; P=0.019), AOP (OR 19.64; 95%CI 4.27 to 90.35; P<0.001), and sepsis (OR 10.93; 95%CI 2.37 to 45.53; P=0.002) Conclusion FiO2 setting of more than 25% at the start of weaning, anemia, AOP, and sepsis produce a significant probability of HFNC weaning failure.
Comparison of oral caffeine and oral theophylline for apnea of prematurity: A randomized clinical trial Anggrainy, Nensy; Sarosa, Gatot Irawan; Suswihardhyono, Adhie Nur Radityo
Paediatrica Indonesiana Vol. 64 No. 4 (2024): July 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.4.2024.350-5

Abstract

Background Caffeine and theophylline are methylxanthine compounds that have been widely used in the treatment of apnea of prematurity (AOP). Previous studies comparing the two agents have shown inconsistent results and have mostly used intravenous preparations. Objective To assess the effectiveness of oral administration of caffeine compared to oral theophylline as therapy for apnea of prematurity. Methods Fifty consecutively recruited premature neonates (gestational age 28-34 weeks, birth weight <2,500 g) with AOP who were able to tolerate at least 10 mL/kg of enteral feeding were randomized to receive either oral caffeine or oral theophylline for seven days. The main outcome was the daily frequency of apnea after treatment. Secondary outcomes were duration of oxygen or CPAP administration, duration of oxygen fraction (FiO2) taper to reach 21%, time to achievement of full feeding tolerance, length of hospital stay, and side effects. Results We randomized 25 subjects into each group. The distribution of baseline characteristics (gender, gestational age, mode of delivery, birth weight and length, age at onset of AOP, and initial frequency of AOP) was similar between both groups. The mean daily number of apnea episodes after treatment was significantly higher in the caffeine group compared to the theophylline group [3.16 (SD 1.31) vs. 2.28 (SD 1.40); P=0.031]. The caffeine group, compared to the theophylline group, also had a longer mean duration of oxygen or CPAP use [12.56 (SD 7.67) days vs. 8.40 (SD 6.41) days; P=0.030] and duration of FiO2 taper [5.76 (SD 2.68) vs. 4.08 (SD 2.54); P=0.035]. There were no significant differences in mean time to full feeding and mean length of hospital stay. There was no significant difference in the occurrence of side effects between the two groups. Conclusion In premature neonates with AOP, oral theophylline is slightly more effective than oral caffeine in reducing the frequency of apnea and is associated with a shorter duration of oxygen or CPAP use and duration to reach 21% FiO2.
The Relationship Between the Duration of Kangaroo Mother Care and Edinburgh Postnatal Depression Scale Outcomes in Mothers with Preterm Infants Pranoto, Ivena Celia Eileen; Suswihardhyono, Adhie Nur Radityo; Wardani, Natalia Dewi
Journal of Biomedicine and Translational Research Vol 10, No 2 (2024): August 2024
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v10i2.20443

Abstract

Background: Preterm birth has a negative impact on the health of the baby and increases the risk of postpartum depression in mothers. Kangaroo mother care (KMC) is a preterm baby care which is considered to increase bonding between mother and baby, thereby reducing the incidence of postpartum depression, which can be evaluated using the Edinburgh Postnatal Depression Scale (EPDS) instrument.Objective: To find out the relationship between the duration of KMC and EPDS outcomes in mothers with preterm infants.Methods: This study used a quasi-experimental method with non-randomized control group pre-test and post-test design and was conducted on 34 mothers with preterm infants who gave birth at Dr. Kariadi Hospital Semarang. The research subjects were selected using consecutive sampling method and were asked to perform kangaroo mother care for 60 minutes daily (control group) and 120 minutes daily (treatment group) for 14 days. Evaluation was carried out using the Edinburgh Postnatal Depression Scale questionnaire, which was completed twice, as a pre-test and post-test. Data analysis was performed using paired sample T-test and independent samples T-test to determine the relationship between variables.Results: Results showed that there was a significant relationship between the duration of KMC and EPDS outcomes. The difference between the decreased of EPDS scores in the control and treatment groups was significant (p=0.017). The significant decrease of EPDS score was found in the treatment group (p<0.001). The decrease of EPDS score in the control group was not significant (p=0.704).Conclusion: Increasing duration of KMC lowers the score of EPDS in mothers with preterm infants.
Perbedaan Karakteristik Kematian Neonatus Sebelum dan Saat Pandemi COVID-19 di RSUP Dr Kariadi Al Ahdi, Siti Zahra Zahira; Suswihardhyono, Adhie Nur Radityo
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pandemi COVID-19 membawa perubahan besar dalam pola hidup masyarakat, sistem layanan kesehatan, dan aksesibilitas pelayanan kesehatan. Selain itu, banyaknya ibu hamil yang terkena COVID-19, dan neonatus yang lahir dari ibu COVID-19, diyakini berpengaruh dan memberikan perbedaan karakteristik kematian neonatus sebelum dan saat pandemi COVID-19. Menganalisis perbedaan karakteristik kematian neonatus sebelum dan saat pandemi COVID-19 di RSUP Dr Kariadi. Penelitian ini merupakan penelitian dengan metode cross sectional. Penelitian ini menggunakan data dari neonatus yang mengalami kematian sebelum (2016 – 2019) dan saat (2020 – 2023) pandemi COVID-19 di RSUP Dr Kariadi, kemudian membandingkan karakteristik kematian neonatus tersebut. Dengan analisis bivariat, ditemukan perbedaan yang siginifikan antara perbedaan karakteristik kematian neonatus berdasarkan usia gestasi (p=0,016) dan pemeriksaan ANC (p=0,023) sebelum dan saat pandemi COVID-19 di RSUP Dr Kariadi. Namun, tidak terdapat perbedaan karakteristik kematian neonatus berdasarkan jenis kelamin neonatus, penyebab kematian, usia kematian, jenis persalinan, usia ibu, preeklamsia, anemia ibu hamil, dan KPD sebelum dan saat pandemi COVID-19 di RSUP Dr Kariadi. Terdapat perbedaan karakteristik usia gestasi ibu dan pemeriksaan ANC pada neonatus yang mengalami kematian sebelum dan saat pandemi COVID-19 di RSUP Dr. Kariadi.
Perbedaan Karakteristik Kematian Neonatus Sebelum dan Saat Pandemi COVID-19 di RSUP Dr Kariadi Al Ahdi, Siti Zahra Zahira; Suswihardhyono, Adhie Nur Radityo
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/.v7i2.345

Abstract

Pandemi COVID-19 membawa perubahan besar dalam pola hidup masyarakat, sistem layanan kesehatan, dan aksesibilitas pelayanan kesehatan. Selain itu, banyaknya ibu hamil yang terkena COVID-19, dan neonatus yang lahir dari ibu COVID-19, diyakini berpengaruh dan memberikan perbedaan karakteristik kematian neonatus sebelum dan saat pandemi COVID-19. Menganalisis perbedaan karakteristik kematian neonatus sebelum dan saat pandemi COVID-19 di RSUP Dr Kariadi. Penelitian ini merupakan penelitian dengan metode cross sectional. Penelitian ini menggunakan data dari neonatus yang mengalami kematian sebelum (2016 – 2019) dan saat (2020 – 2023) pandemi COVID-19 di RSUP Dr Kariadi, kemudian membandingkan karakteristik kematian neonatus tersebut. Dengan analisis bivariat, ditemukan perbedaan yang siginifikan antara perbedaan karakteristik kematian neonatus berdasarkan usia gestasi (p=0,016) dan pemeriksaan ANC (p=0,023) sebelum dan saat pandemi COVID-19 di RSUP Dr Kariadi. Namun, tidak terdapat perbedaan karakteristik kematian neonatus berdasarkan jenis kelamin neonatus, penyebab kematian, usia kematian, jenis persalinan, usia ibu, preeklamsia, anemia ibu hamil, dan KPD sebelum dan saat pandemi COVID-19 di RSUP Dr Kariadi. Terdapat perbedaan karakteristik usia gestasi ibu dan pemeriksaan ANC pada neonatus yang mengalami kematian sebelum dan saat pandemi COVID-19 di RSUP Dr. Kariadi.
Co-Authors Al Ahdi, Siti Zahra Zahira Anggrainy, Nensy Ari Budi Himawan Arsita Eka Rini Belia Dwi Hapsari Nugraheni Daffa Hafizh Afian Dwi Wastoro Dadiyanto, Dwi Wastoro Gatot Irawan Sarosa, Gatot Irawan Heru Muryawan Mohamad Syarofil Anam Najih Rama Eka Putra Natalia Dewi Wardani Pranoto, Ivena Celia Eileen Sahyuni, Riza