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All Journal Health and Medical Journal Consilium Sanitatis: Journal of Health Science and Policy
Raveinal Raveinal
Andalas University
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Lupus Eritematosus Sistemik pada Pria Harry Andrean; Raveinal Raveinal
Health and Medical Journal Vol 3, No 2 (2021): HEME July 2021
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (342.501 KB) | DOI: 10.33854/heme.v3i2.664

Abstract

Introduction: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by presence of nucleus autoantibody and affected multiple organ. Systemic lupus erythematosus is more common in women than men with ratio 2:1 to 15:1. Men with SLE often have a more aggressive clinical course, lead to a poorer prognosis compared with women with SLE. Case Report: A man, 29 years old came to hospital with main complain joint pain increased since 1 week ago, accompanied with red spot on face, trunk, hands, foot, and back, hair loss, swollen leg, mouth ulcer, and fatique. Malar rash and discoid rash were identified from physical examination. From laboratorium, ANA profile was positive for RNP/Sm, Sm, dsDNA, and histone. Skin biopsy showed a lupus discoid. Conclusion: The patient was treated with pulse-dose methylprednisolone for 3 days and showed a good response clinically.
Profil Pasien Lupus Eritematosus Sistemik di RSUP Dr. M. Djamil Padang Tahun 2020-2021 Elfi Fauzana Akmal; Dwitya Elvira; Noverika Windasari; Malinda Meinapuri; Raveinal Raveinal; Yulistini Yulistini
Consilium Sanitatis: Journal of Health Science and Policy Vol. 2 No. 2 (2024)
Publisher : EDUPEDIA Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56855/jhsp.v2i2.1867

Abstract

Objective: To understand the profile of SLE patients at RSUP.Dr.M.Djamil Padang period of 2020-2021. Methods: The research is a descriptive type with a retrospective approach. Medical record data were collected using total sampling technique,189 samples met the inclusion criteria. Data analysis using Microsoft Excel. Results: The study found that the majority of characteristics include female patients (95.8%), age group 17-25 years (33.9%), housewives (41.8%), medium-level education (66.1%), and of Minangkabau ethnicity (86.8%). Most patients had a disease duration of ≥ 2 years (78.8%), mild disease activity (36%), the most common clinical manifestation being mucocutaneous involvement (82%). ANA Profile results, the most prevalent finding was positive dsDNA (25.4%). Patients meeting ACR 1997 criteria were 57.1%, SLICC 2012 35.4%, and EULAR 2019 10.6%. The most frequently therapy was a combination of HCQ and glucocorticoids (45%), while the most common patient outcome was survival (96.8%). Conclusion: Majority of SLE patients at RSUP Dr.M.Djamil Padang are in the productive age group with mild disease activity. The majority of patients have good outcome, indicating a favorable prognosis for SLE at RSUP Dr. M. Djamil Padang.
Co-Authors Dwitya Elvira Elfi Fauzana Akmal Harry Andrean Malinda Meinapuri Noverika Windasari Yulistini, Yulistini