Eric Daniel Tenda
Division Of Pulmonology And Critical Medicine, Department Of Internal Medicine, Faculty Of Medicine, Universitas Indonesia, National General Hospital Of Dr. Cipto Mangunkusumo, Indonesia

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Papilla Vaterƒs Tumor in Elderly: an Interdisciplinary Issue Eric Daniel Tenda; Murdani Abdullah; Kuntjoro Harimurti; Edy Rizal Wahyudi; Czeresna Heriawan Soejono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 11, NUMBER 3, December 2010
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/1132010155-159

Abstract

Tumors of the papilla Vater are very rare. Papilla Vater’s tumors are benign or malignant tumors in the ampulla of Vater and periampullary region. Blockage of ampulla leads to the development of obstructive jaundice; intermittent cholangitis, epigastric discomfort and weight loss. Treatment possibilities include endoscopic ampulectomy, surgical transduodenal excision of tumors of the ampulla and pancreatoduodenectomy (PDE). Prognosis depends on histological typing of the tumor and their clinical stage. We report a case of papilla Vater’s tumor in elderly with comorbidities based on literature review. A 68-year-old female patient was referred for evaluation of intra and extra hepatic bile duct dilatation noted on abdominal ultrasonography. She complained of intermittent epigastric and right upper abdominal pain, with yellowish skin for two months. The laboratory findings showed leukocytosis, hyperbilirubinemia, abnormal liver function test, and high Ca 19-9. An endoscopic retrograde cholangiopancreatography (ERCP) revealed a distal obstruction caused by papilla Vater’s tumor. Abdominal computed tomography (CT) with contrast, revealed a dilated common bile duct and pancreatic duct. The histologic evaluation was highly suggestive for dysplasia. She is now on a schedule for a Whipple procedure. To make a true diagnosis and optimal treatment of papilla Vater’s tumor is multimodal. By doing a comprehensive geriatric assessment, with a careful modality selection, a Whipple procedure can be performed in elderly (65 years) safely. The post operative morbidity and mortality depends on their multi morbidity. Surgical, endoscopic, or radiologic biliary decompression; relief of gastric outlet obstruction; and adequate pain control may improve the quality of life but do not affect overall survival rate. By building a great interdisciplinary teamwork, the quality of life increased as follows.Keywords: papilla Vater tumor, elderly, Whipple procedure
The Effect of Branched Chain Amino Acids and L-Ornithine L-Aspartate Combination as The Late Evening Snacks on Nutritional Status and Minimal Hepatic Encephalopathy in Liver Cirrhosis Eric Daniel Tenda; Irsan Hasan; Andri Sanityoso; Siti Setiati
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 3, Desember 2012
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.89 KB) | DOI: 10.24871/1332012151-156

Abstract

ABSTRACTBackground:Minimal hepatic encephalopathy (MHE) in liver cirrhotic patients is critical manifestation of low grade hepatic encephalopaty (HE), is caused quality of life decrease and risk of deteriorating into distinct HE. The study was conducted to asses the effect of combination of branched-chain amino acids (BCAA) and L-ornithine L-aspartate (LOLA), which was given late evening, on nutritional status and degree of HE.Method: This single-blind randomized study was conducted on liver cirrhotic outpatients in hepatology clinic of Cipto Mangunkusumo Hospital period June 2011-June 2012. The study subjects were divided into two groups, group of late evening snack (LS) and day snack (DS). Each group was supplemented with combination of milk of BCAAs and LOLA (3.7 g/serving). Evaluation based on history, physical examination, laboratory tests and critical flicker frequency (CFF) was performed one month after the intervention. Data were statistically analyzed with SPSS 15.Results: Thirty-two patients whose the inclusion criteria were divided into 16 subjects for each group, LS and DS. After one month of the intervention, the average level of prealbumin for DS group was increased statistically significant (p 0.001), but not significant for LS group (p = 0.259). The increase of average body weight,mid-arm muscle circumference (MAMC) and CFF test result in both groups. There was no improvement on subject global assessment (SGA) score after one month intervention in both groups.Conclusion: This study proved that giving combination of BCAAs and LOLA may improve the condition of MHE, however for nutritional status can not be assessed. Keywords: minimal hepatic encephalopathy, BCAAs, LOLA, prealbumin, SGA score, nutritional status
Respiratory Syncytial Virus Pneumonia in an Elderly Patient: A Case Report and Clinical Review Eric Daniel Tenda; Almerveldy Azaria Dohong; Sahat Halim; Alfino Syahputra; Muhammad Aziz Arridho
Indonesia Journal of Chest Critical Emergency Medicine Vol 13 No 1 (2026): Respiratory Syncytial VirusPneumoniain an Elderly Patient
Publisher : PERPARI (Perhimpunan Respirologi Indonesia)

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Abstract

Background: Respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract infection and is increasingly recognized as a clinically significant cause of pneumonia in older adults. However, RSV remains underdiagnosed in adult pneumonia because clinical and radiologic features overlap with bacterial pneumonia and other viral infections, and RSV testing is not routinely performed. Case: A 91-year-old man presented with one day of cough, low-grade fever, reduced appetite, generalized weakness, and acute delirium. On admission, he was hemodynamically stable with oxygen saturation 97–98% on room air. Initial laboratory tests showed elevated C-reactive protein (20.7 mg/L), mild lymphopenia, microcytic anemia (hemoglobin 10.0 g/dL), and mild hyponatremia (sodium 132 mEq/L). Chest radiography revealed bilateral pulmonary infiltrates. A multiplex acute respiratory infection PCR panel detected RSV type A, while other respiratory viruses and atypical bacterial pathogens were negative. On day 3 of hospitalization, he developed acute hypoxemia (SpO₂ 86–88% on room air) accompanied by a marked rise in inflammatory markers (CRP peak 148 mg/L; procalcitonin 0.44 ng/mL). He improved with supplemental oxygen, intravenous methylprednisolone, and a macrolide antibiotic, and was discharged in stable condition on day 7. Discussion: This case highlights RSV as an important and often overlooked etiology of community-acquired pneumonia in very old patients, including atypical presentations such as delirium and late clinical deterioration after an initially stable course. Molecular diagnostics (PCR-based panels) can provide timely etiologic confirmation, support infection control measures, and guide antimicrobial stewardship, particularly when bacterial co-infection is uncertain. Conclusion: RSV should be considered in elderly patients with pneumonia, especially during periods of respiratory virus circulation. Early molecular testing may improve diagnostic accuracy and optimize clinical management and prevention strategies in high-risk older adults. Keyword: respiratory syncytial virus; pneumonia; elderly; multiplex PCR; case report
Artificial Intelligence in Bronchoscopy for Pulmonary Disease: A Systematic Review of Randomized Controlled Trials Eric Daniel Tenda; Almerveldy Azaria Dohong; Nadia Iqbal; Aziza Harris; Steffi Cong Andi Nata; Muhammad Aziz Arridho; Alfino Syahputra; Sahat Halim
Indonesia Journal of Chest Critical Emergency Medicine Vol 13 No 1 (2026): Artificial Intelligence in Bronchoscopy for Pulmonary Disease: A Systematic Revi
Publisher : PERPARI (Perhimpunan Respirologi Indonesia)

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Abstract

Background: Bronchoscopy is a core diagnostic and therapeutic procedure for pulmonary diseases, yet performance is highly operator dependent, contributing to variability in airway inspection completeness and procedural efficiency. Artificial intelligence (AI) systems have been developed to support real time airway anatomy recognition, navigation, and performance feedback. This systematic review summarizes randomized controlled trial evidence on the impact of AI guided bronchoscopy on procedural performance. Methods: This review followed PRISMA guidance and was registered in PROSPERO. We searched PubMed/MEDLINE, ScienceDirect, and SAGE Journals from database inception to January 2026. Two reviewers independently screened studies and extracted data. Risk of bias was assessed using the RoB 2 tool. Given heterogeneity in interventions, populations, and outcome definitions, results were synthesized narratively. Results: From 1,654 records, four randomized controlled trials met inclusion criteria. All studies were conducted in simulation settings and enrolled participants with varying experience (novice to experienced bronchoscopists, including critical care physicians). Overall, AI guided bronchoscopy favored AI supported groups compared with comparators (no AI, written instruction, directed self learning, or expert instruction), showing improvements in key performance domains such as inspection completeness and structured progression, as well as efficiency related metrics including intersegmental time and or total procedure time. Conclusion: Simulation based RCT evidence supports AI as a promising approach to improve standardization and procedural performance in bronchoscopy training. Multicenter patient based randomized trials are warranted to confirm benefits on clinically meaningful outcomes. Keywords: artificial intelligence; bronchoscopy; randomized controlled trial; simulation based training; procedural performance.