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All Journal Jurnal Biotek Medisiana Indonesia Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Jurnal Biomedika dan Kesehatan Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Respiratory Science Jurnal Pelayanan Pastoral (JPP)
Yanto Sandy Tjang
Division of Thoracic & Cardiovascular Surgery, Department of Surgery
Religion Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Epidemic Burden of Cardiovascular Disease in Indonesia Tjang, Yanto Sandy; Susanto, Djap Hadi
Jurnal Biotek Medisiana Indonesia Vol 1, No 1 (2009)
Publisher : Pusat BTDK

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Abstract

Transformasi luar biasa di bidang ekonomi dan urbanisasi telah mengubah struktur de­mografi sosial di Indonesia sehingga menyebabkan pergeseran besar dalam pola makan dan penyebab kematian. Sebagai penyebab kematian utama, epidemik penyakit kardiovaskuler telah menjadi masalah kesehatan masyarakat yang serius. Masalah menjadi lebih sulit dengan adanya beban ganda penyakit yakni penyakit-penyakit tidak menular menjadi lebih menonjol sementara penyakit-penyakit menular masih belum teratasi karena sanitasi lingkungan yang buruk akibat tidak baiknya sistem pelayanan kesehatan. Penyakit kardiovaskuler sangat berhubungan dengan beberapa faktor risiko yang dapat diubah, seperti kebiasaan merokok tembakau, perubahan gaya hidup (makanan yang tidak sehat dan kurangnya aktivitas fisik), dan kelebihan berat badan/kegemukan. Strategi dengan target individu-individu berisiko tinggi dan upaya pencegahan berlandaskan populasi jelas sangat dibutuhkan untuk menghadapi beban epidemik penyakit kardiovaskuler, disamping menyediakan pelayanan kesehatan baku bagi penduduk Indonesia. Semua strategi ini harus disertai adanya keinginan politik untuk mendukung perubahan kebijakan kesehatan yang diperlukan. Tulisan ini memberikan gambaran singkat tentang beban epidemik penyakit kardiovaskuler di negara-negara berkembang seperti Indonesia, dengan penekanan pada faktor-faktor risiko penting maupun strategi pencegahan dan pengendaliannya.   Kata kunci: Penyakit kardiovaskuler, faktor risiko, pencegahan
FACTORS ASSOCIATED WITH CHRONIC KIDNEY DISEASE AMONG PATIENTS UNDERGOING HEMODIALYSIS Tjang, Yanto Sandy; Pandelaki, Paulus Anung Anindita
Majalah Kedokteran Indonesia Vol 68 No 4 (2018): Journal of the Indonesian Medical Association Majalah Kedokteran Indonesia Volum
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

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Abstract

Introduction: The development of chronic kidney disease (CKD) and later proportion of decline in renal function are diverse among individuals. This reflects the multifactorial biological mechanisms that are involved in the underlying disease process. The risk factors and resources for care of CKD also vary from place to place. Identifying the risk factors of CKD is crucial and develop prevention strategies, including screening, might be beneficial to reduce burden cost, morbidity and mortality of CKD. We aim at identifying the factors associated with CKD in individuals who have undergone hemodialysis. Material and Methods: All adult patients (age >18 years) admitted to the department of internal medicine either as in- or out-patient for undergoing hemodialysis at the Mardi Rahayu Hospital in Kudus, Middle Java, Indonesia from January to August 2016 were included in the study. Results: Eighty-two patients were evaluated during the study period. Most of the patients were in older age (> 50 years old). Sixty (73%) were male and 22 (27%) were female patients. Fifty (61%) patients had mild anemia, 23 (28%) patients had moderate anemia and 8 (10%) patients had severe anemia. Among 82 patients, 77 (94%) of the patients were hypertensive, 19 (23%) of the patients had DM, 23 (28%) of the patients had renal stone, 8 (10%) of the patients had renal cysts, and 7 (9%) of the patients suffered from glomerulonephritis. Conclusion: Older age, male gender, anemia, and hypertension were factors that associated with CKD among patients undergoing hemodialysis. Keywords: chronic kidney disease, risk factors, hemodialysis, anemia, hypertension
STRESS LEVEL OF MEDICAL STUDENTS IN ONLINE LEARNING DURING COVID-19 PANDEMIC AND ITS IMPACT ON ACADEMIC ACHIEVEMENT Tjang, Yanto Sandy; Prihatiningsih, Titi Savitri; Prabandari, Yayi Suryo
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 12, No 1 (2023): Maret
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.76645

Abstract

research on its prevalence is still very few and inconclusive. The relationship between stress and academic achievement in medical students remains a matter of debate. This study aims to determine the stress level of medical students in online learning during the COVID-19 pandemic and its impact on academic achievement.Method: This descriptive-analytical study used a cross-sectional design on undergraduate medical students from the 2019-2021 class. The questionnaire distributed online contained questions related to characteristics of respondents, 14 questions from DASS-42 questionnaire to measure stress, and questions related to respondents' perceptions of online learning and semester achievement index (IPS). Data were analysed descriptively and analytically using logistic regression method with the help of SPSS Statistics 26 software. Results: Of 431 students, 411 (95%) students participated in this study. The prevalence of stress in respondents was 41.8%, majority was mild (13.4%) and moderate (13.9%). Lack of interaction between lecturers and students increased 1,691 times the risk of stress. A total of 403 (98.1%) respondents had IPS ≥ 3. Stress on respondents did not have negative impact on academic achievement, although statistically not significant (OR = 0.831; 95% CI = 0.196-3.524; p-value 0.801).Conclusion: The prevalence of stress for medical students in online learning during COVID-19 is quite high, majority was mild and moderate. Lack of interaction between lecturers and students increased risk of stress. Majority of respondents have good IPS. Stress on respondents apparently did not have negative impact on academic achievement.
Factors Associated with Delayed 2-Month Sputum Smear Conversion in MDR-TB Patients Treated with All-Oral Regimen at Persahabatan Hospital Sitinjak, Sahat Anugerah Immanuel; Harfiani, Erna; Tjang, Yanto Sandy; Muktamiroh, Hikmah; Sutarto, Riyadi
Respiratory Science Vol. 6 No. 1 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i1.183

Abstract

Background: The emergence of multidrug-resistant tuberculosis (MDR-TB) presents significant challenges in achieving treatment success. Sputum conversion time, an essential indicator of treatment progress, varies among patients and may be influenced by demographic and clinical factors. This study aimed to identify factors associated with sputum conversion time in MDR-TB patients treated with all-oral regimens at Persahabatan Hospital during the 2021–2022 period. Method: This retrospective cohort study analyzed data from 154 MDR-TB patients treated with all-oral regimens at Persahabatan Hospital. Patients were categorized by sputum conversion time (≤2 months or >2 months). Independent variables included age, sex, diabetes mellitus, anemia, previous TB treatment, pulmonary cavitation, education level, marital status, and initial sputum AFB results. Inclusion criteria were primary pulmonary MDR-TB patients confirmed via sputum culture, aged ≥20 years, and treated per Indonesian national guidelines. Logistic regression analyses identified significant factors. Results: Among the nine factors studied, four significantly influenced sputum conversion time: elderly age, anemia, pulmonary cavitation, and initial sputum AFB results. Older age (≥60 years) was protective against delayed conversion, while anemia, pulmonary cavitation, and higher initial sputum AFB results were associated with prolonged conversion times. Conclusion: Factors such as anemia, pulmonary cavitation, and initial sputum results are associated with delayed sputum conversion, with elderly age as a protective factor against delayed sputum conversion.
Pengaruh Cotrimoxazole Terhadap Perkembangan Neural Tube Embrio Ayam Pamuji, Alifia Shafanaura; Fauziah, Cut; Tjang, Yanto Sandy; Thadeus, Maria Selvester
Jurnal Biomedika dan Kesehatan Vol 7 No 2 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.190-198

Abstract

Background In Indonesia, congenital abnormalities are still very high. Neural Tube Defect (NTD) is one of the most common congenital abnormalities. NTD occurs due to the failure of neural plate closing. One of the risk factors for NTD is folic acid deficiency. Drug use during pregnancy is one of the risk factors for congenital abnormalities. Cotrimoxazole is an anti-folate drug that still has pros and cons regarding its potential to cause NTD. Human embryonic brain development can be simulated using chicken embryos. This study aimed to determine the effect of Cotrimoxazole on the development of the chicken embryo's neural tube. Methods This study used a post-test-only control group design. The number of samples is 30 eggs and the sampling method was simple random sampling. The dose of Cotrimoxazole used was 0; 60; and 120 mg/kg per egg then the eggs were incubated for 72 hours. Data analysis was based on sample characteristics and bivariate analysis using the comparative Kruskal-Wallis test with the post-hoc test. Results In this study, 11 out of 30 eggs could be analyzed. The results were obtained by observing the number of brain vesicles. There was a significant difference in the number of brain vesicles (p= 0.046) between the study groups from the Kruskal-Wallis test. Conclusions Cotrimoxazole administration showed an effect on neural tube development of chicken embryos when compared to controls.
Euthanasia dan Martabat Manusia: Kajian Hukum, Medis, Etis, dan Moral Katolik Tjang, Yanto Sandy; Acin, Mayong Andreas
Jurnal Pelayanan Pastoral Jurnal Pelayanan Pastoral (JPP) Vol. 6 No. 2 Oktober 2025
Publisher : Unit Penelitian dan Pengabdian kepada Masyarakat (UPPM), STP-IPI Malang.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53544/jpp.v6i2.804

Abstract

This study aims to comprehensively analyze the phenomenon of euthanasia through a multidimensional approach encompassing legal, medical, ethical, and Catholic moral perspectives, placing human dignity at the core of reflection. The issue of euthanasia presents a complex dilemma between respect for individual autonomy and the moral duty to uphold the universal value of life. In Indonesia, euthanasia is strictly prohibited as it violates the constitutional and criminal law principles protecting the right to life as a fundamental human right. Conversely, countries such as the Netherlands, Belgium, and Canada have legalized euthanasia under stringent regulations requiring patient consent, terminal medical conditions, and professional responsibility from physicians. From a medical ethics perspective, the principles of autonomy, beneficence, non-maleficence, and justice form the moral foundation for end-of-life decision-making. The Catholic Church, through Evangelium Vitae and the Catechism of the Catholic Church, rejects active euthanasia as contrary to the sanctity of life and human dignity as imago Dei. However, discontinuing extraordinary or disproportionate medical treatment is considered permissible under the principle of proportionality and respect for natural death. The study concludes that a multidimensional approach offers a balanced framework for understanding euthanasia, safeguarding human dignity, and promoting palliative care as a more ethical, humane, and just alternative.
Co-Authors Cut Fauziah Djap Hadi Susanto Erna Harfiani Maria Selvester Thadeus Mayong Andreas Acin Pamuji, Alifia Shafanaura Pandelaki, Paulus Anung Anindita Sitinjak, Sahat Anugerah Immanuel Sutarto, Riyadi Titi Savitri Prihatiningsih Yayi Suryo Prabandari