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All Journal Borneo Journal Of Pharmascientech Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan Journal of Pharmaceutical Care and Sciences
Darini Kurniawati
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Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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POTENSI ANTISEPTIK POLIHERBAL DAUN SIRIH (Piper betle), KULIT JERUK NIPIS (Citrus aurantifolia) DAN TANAMAN BUNDUNG (Actinuscirpus grossus) PADA TINDAKAN KEPERAWATAN DAN KEBIDANAN Darini Kurniawati; Noval Noval; Kunti Nastiti
DINAMIKA KESEHATAN: JURNAL KEBIDANAN DAN KEPERAWATAN Vol 11, No 1 (2020): Dinamika Kesehatan Jurnal Kebidanan dan Keperawatan
Publisher : Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (200.566 KB) | DOI: 10.33859/dksm.v11i1.552

Abstract

Latar Belakang: Antiseptik adalah senyawa kimia yang digunakan untuk membunuh atau menghambat pertumbuhan mikroorganisme pada jaringan yang hidup seperti permukaan kulit dan membran mukosa. Daun sirih, jeruk nipis, bundung sudah banyak digunakan masyarakat untuk obat. Antiseptik dari poliherbal diyakini lebih aman dari pada zat kimia sintetis.Tujuan: Tujuan penelitian ini untuk mengetahui kemampuan antiseptik terhadap bakteri Staphylococcus aureus dari campuran ekstrak daun sirih, jeruk nipis dan bundung sebagai pengganti antiseptic dari bahan zat kimia sintetis pada tindakan keperawatan dan kebidanan.Metode: Metode penelitian adalah eksperimental dengan membuat formulasi uji konsentrasi F1 20%, F2 30%, F3 F4 40% dan F5 50% dan diujikan terhadap bakteri Staphylococcus aureus dengan metode difusi disk.Hasil: Hasil penelitian menunjukkan bahwa daya antiseptik Daun Sirih, Jeruk Nipis dan  Bundung efektif sebagai antiseptic pada konsentrasi 40%  dengan efektifitas yang sama dari bahan antiseptic zat kimia sintetis. Konsentrasi  F1 20% tidak ada daya hambat dengan nilai yang sama pada kontrol negatif, pada F2 30% terdapat daya hambat lemah sebesar 7 mm, pada F3 40% terdapat daya hambat kuat sebesar 23 mm sama dengan kontrol positif, dan pada F4 50% terdapat daya hambat sangat kuat lebih besar dari kontrol positif yaitu 40 mm.Simpulan: Antiseptik dari bahan alam kombinasi Daun Sirih, Jeruk Nipis dan Bundung pada konsentrasi 40% mempunyai efektifitas antiseptic yang sama dari antiseptic dengan bahan zat kimia sintetis. Antiseptik poliherbal ini bisa digunakan untuk keperluan tindakan keperawatan dan kebidanan. Kata Kunci: Daun sirih-kulit jeruk nipis-tanaman bundung, antiseptik, tindakan keperawatan dan kebidananAbstractBackground: Antiseptic is a chemical compound used to kill or inhibit the growth of microorganisms in living tissues such as the surface of the skin and mucous membranes. Betel leaf, lime, bundung have been widely used by the community for medicine. Antiseptics from polyherbal are believed to be safer than synthetic chemicals.Purpose: The purpose of this study was to determine the antiseptic ability of Staphylococcus aureus bacteria from a mixture of betel, lime, and bundung extracts as an antiseptic substitute for synthetic chemicals in nursing and obstetrics.Methods: The research method was experimental by making test formulations with concentrations of F1 20%, F2 30%, F3 F4 40%, and F5 50% and tested against Staphylococcus aureus bacteria using the disk diffusion method.Results: The results showed that the antiseptic power of Betel, Lime and Bundung leaves was effective as an antiseptic at a concentration of 40% with the same effectiveness of synthetic chemical antiseptic substances. The concentration of F1 20% has no inhibitory power with the same value in the negative control, at F2 30% there is a weak inhibitory power of 7 mm, at F3 40% there is a strong inhibitory power of 23 mm, the same as the positive control, and at F4 50% there is Very strong inhibition power is greater than the positive control, which is 40 mm.Conclusion: Antiseptic made from natural ingredients a combination of Betel, Lime, and Bundung Leave at a concentration of 40% has the same antiseptic effectiveness as antiseptic with synthetic chemical substances. This polyherbal antiseptic can be used for the purposes of nursing and midwifery action.Keywords: Betel leaf-lime peel-bundung plant, antiseptic, nursing and obstetrics measures
Hubungan Tingkat Pengetahuan Masyarkat Terhadap Penggunaan Antibiotik Di Kelurahan Alalak Utara Shofia Rahmi; Darini Kurniawati; Nurul Hidayah
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 1 (2020): Journal Of Pharmaceutical Care and Science
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (526.923 KB)

Abstract

Background: Antibiotics are drugs that used to treat infections. Irrational use of antibiotics can increase the incidence of bacterial resistance. The proper use of antibiotics is influenced by several factors, one of the factors is knowledge. Objective: Analyze the relationship between the level of society knowledge and rational use of antibiotics in the North Alalak Village. Methods: This research used observational analytics design (non-experimental) and cross – sectional study design. The population are adult communities with ages around 20-60 years in North Alalak Village. The researcher take 45 people as sample by using purposive sampling. Measure tools or instrument that the researcher used is validated questionnaire. Data was analyzed by using Spearman Rho with 95% level of confidence. Results: The results of the respondents knowledge level in good categories were 4 people (8.9%), quite were 25 people (55.6%) and less were 16 people (35.6%). The results of using antibiotics rationally by respondents were 3 people (6.7%) and irrationally by 42 people (93.3%). The prevalence ratio (PR) value obtained was 20.83 and the Spearman rho test results obtained were a significance value of 0.014 (<0.05), a correlation coefficient of 0.364 and a positive correlation direction. There is a correlation between the level of knowledge and the use of antibiotics in the society in North Alalak village. Conclusion: Knowledge about antibiotics is related to rational antibiotic use. People needs to add more information about rational use of antibiotics with counseling guidance, seminars and other information.
Studi Farmakovigilans Obat Herbal Di Kota Banjarmasin Dengan Metode Naranjo Darini Kurniawati; Iwan Yuwindry
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 1 (2021): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (523.358 KB) | DOI: 10.33859/jpcs.v2i1.132

Abstract

Background: Basic Health Research of the Republic of Indonesia in 2018 obtained data that 30.4% of Indonesian people consume traditional herbal medicine in homemade ingredients. The Indonesian government encourages the use of herbs because the raw materials for finished drugs are still obtained from abroad (Dani Pratama, 2020). The purpose of this study was to see the possibility of side effects on the use of herbal medicines for the people of Banjarmasin using the Naranjo method. This research method is descriptive observational with a cross sectional design with purposive sampling with inclusion and exclusion criteria set by researchers in the North Banjarmasin District. Data analysis using Naranjo. The results of the research from the dominant age characteristics data are aged 31-50 years as many as 13 (42%), the majority gender is 22 (71%), the majority of the work status is self-employed 19 (61 %), the majority of the education status is SMA 15 (48 %), majority income status above two million 10 (32 %). The majority of people use herbal medicines 27 (87%), sources of information on herbal medicines from families 20 (65%), the majority of herbal medicines are from traditional medicine shops 11 (35%), the majority of herbal medicines are brewed 11 (35%). From the causality analysis using the Naranjo algorithm, it is known that the patients who used herbal medicines had 6 subjects in the possible category. Conclusion: The incidence of side effects of using herbal medicines in the Possible category. Keywords: herbal medicine, Naranjo, Possible.
Gambaran Kejadian Ikutan Pasca Imunisasi (KIPI) Setelah Melakukan Vaksinasi Covid-19 Pada Masyarakat Banjarmasin Selatan Darini Kurniawati; Iwan Yuwindry; Sariyasih Sariyasih
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (837.294 KB) | DOI: 10.33859/jpcs.v2i2.187

Abstract

ABSTRACT Background : Covid-19 attacks the respiratory tract which first appeared in December 2019 in Wuhan City, Hubei Province, China. The World Health Organization (WHO) has declared it as a global pandemic since March 11, 2020. The COVID-19 vaccination program in Indonesia has started on January 13, 2021. Covid-19 vaccination can cause Post Immunization Adverse Events (AEFI) which can be characterized by mild to moderate symptoms. heavy. Objective : To find how to follow-up events after immunization (KIPI) in the people of southern Banjarmasin after the Covid-19 vaccination. Methods : This research is an observational quantitative research with descriptive research type, this research only describes an object of research, then the research data obtained in the form of numbers will be qualitatively obtained so that the results obtained can be described. This research was conducted using the naranjo algorithm which was distributed to the public and input via Google Form. Results : This study shows that 37 respondents with a percentage of men 51% and women 49% obtained a score of 4-8, namely "Most likely Terjasi ROM" with a total of 13 respondents, who used the Sinovac vaccine in 11 respondents and there were 2 moderna respondents. then with a score of 1-3, namely "Probability of ROM" with a total of 23 respondents who used the Sinovac vaccine. Then with a score of 0 which is "it is doubtful that ROM will occur" there are as many as 1 respondent with the Sinovac vaccine. Of the two vaccines, the Sinovac vaccine has an effectiveness of 56-65% while the Modena vaccine has an effectiveness of 94.1%. The common side effects of the Sinovac vaccine include injection pain, fever, fatigue, while the most common side effects of the moderna vaccine are fever, pain on injection, headache, and nausea. Conclusion : it can be concluded that Post-Immunization Adverse Events (AEFI) of respondents who vaccinated against covid-19 were 23 respondents in the Possible category, 13 respondents in the Probable category, and 1 respondent in the Doubtful category.
Hubungan Tingkat Pengetahuan Masyarkat Terhadap Penggunaan Antibiotik Di Kelurahan Alalak Utara Shofia Rahmi; Darini Kurniawati; Nurul Hidayah
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 1 (2020): Journal Of Pharmaceutical Care and Science
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Antibiotics are drugs that used to treat infections. Irrational use of antibiotics can increase the incidence of bacterial resistance. The proper use of antibiotics is influenced by several factors, one of the factors is knowledge. Objective: Analyze the relationship between the level of society knowledge and rational use of antibiotics in the North Alalak Village. Methods: This research used observational analytics design (non-experimental) and cross – sectional study design. The population are adult communities with ages around 20-60 years in North Alalak Village. The researcher take 45 people as sample by using purposive sampling. Measure tools or instrument that the researcher used is validated questionnaire. Data was analyzed by using Spearman Rho with 95% level of confidence. Results: The results of the respondents knowledge level in good categories were 4 people (8.9%), quite were 25 people (55.6%) and less were 16 people (35.6%). The results of using antibiotics rationally by respondents were 3 people (6.7%) and irrationally by 42 people (93.3%). The prevalence ratio (PR) value obtained was 20.83 and the Spearman rho test results obtained were a significance value of 0.014 (<0.05), a correlation coefficient of 0.364 and a positive correlation direction. There is a correlation between the level of knowledge and the use of antibiotics in the society in North Alalak village. Conclusion: Knowledge about antibiotics is related to rational antibiotic use. People needs to add more information about rational use of antibiotics with counseling guidance, seminars and other information.
POTENSI ANTISEPTIK POLIHERBAL DAUN SIRIH (Piper betle), KULIT JERUK NIPIS (Citrus aurantifolia) DAN TANAMAN BUNDUNG (Actinuscirpus grossus) PADA TINDAKAN KEPERAWATAN DAN KEBIDANAN Darini Kurniawati; Noval Noval; Kunti Nastiti
DINAMIKA KESEHATAN: JURNAL KEBIDANAN DAN KEPERAWATAN Vol 11, No 1 (2020): Dinamika Kesehatan Jurnal Kebidanan dan Keperawatan
Publisher : Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/dksm.v11i1.552

Abstract

Latar Belakang: Antiseptik adalah senyawa kimia yang digunakan untuk membunuh atau menghambat pertumbuhan mikroorganisme pada jaringan yang hidup seperti permukaan kulit dan membran mukosa. Daun sirih, jeruk nipis, bundung sudah banyak digunakan masyarakat untuk obat. Antiseptik dari poliherbal diyakini lebih aman dari pada zat kimia sintetis.Tujuan: Tujuan penelitian ini untuk mengetahui kemampuan antiseptik terhadap bakteri Staphylococcus aureus dari campuran ekstrak daun sirih, jeruk nipis dan bundung sebagai pengganti antiseptic dari bahan zat kimia sintetis pada tindakan keperawatan dan kebidanan.Metode: Metode penelitian adalah eksperimental dengan membuat formulasi uji konsentrasi F1 20%, F2 30%, F3 F4 40% dan F5 50% dan diujikan terhadap bakteri Staphylococcus aureus dengan metode difusi disk.Hasil: Hasil penelitian menunjukkan bahwa daya antiseptik Daun Sirih, Jeruk Nipis dan  Bundung efektif sebagai antiseptic pada konsentrasi 40%  dengan efektifitas yang sama dari bahan antiseptic zat kimia sintetis. Konsentrasi  F1 20% tidak ada daya hambat dengan nilai yang sama pada kontrol negatif, pada F2 30% terdapat daya hambat lemah sebesar 7 mm, pada F3 40% terdapat daya hambat kuat sebesar 23 mm sama dengan kontrol positif, dan pada F4 50% terdapat daya hambat sangat kuat lebih besar dari kontrol positif yaitu 40 mm.Simpulan: Antiseptik dari bahan alam kombinasi Daun Sirih, Jeruk Nipis dan Bundung pada konsentrasi 40% mempunyai efektifitas antiseptic yang sama dari antiseptic dengan bahan zat kimia sintetis. Antiseptik poliherbal ini bisa digunakan untuk keperluan tindakan keperawatan dan kebidanan. Kata Kunci: Daun sirih-kulit jeruk nipis-tanaman bundung, antiseptik, tindakan keperawatan dan kebidananAbstractBackground: Antiseptic is a chemical compound used to kill or inhibit the growth of microorganisms in living tissues such as the surface of the skin and mucous membranes. Betel leaf, lime, bundung have been widely used by the community for medicine. Antiseptics from polyherbal are believed to be safer than synthetic chemicals.Purpose: The purpose of this study was to determine the antiseptic ability of Staphylococcus aureus bacteria from a mixture of betel, lime, and bundung extracts as an antiseptic substitute for synthetic chemicals in nursing and obstetrics.Methods: The research method was experimental by making test formulations with concentrations of F1 20%, F2 30%, F3 F4 40%, and F5 50% and tested against Staphylococcus aureus bacteria using the disk diffusion method.Results: The results showed that the antiseptic power of Betel, Lime and Bundung leaves was effective as an antiseptic at a concentration of 40% with the same effectiveness of synthetic chemical antiseptic substances. The concentration of F1 20% has no inhibitory power with the same value in the negative control, at F2 30% there is a weak inhibitory power of 7 mm, at F3 40% there is a strong inhibitory power of 23 mm, the same as the positive control, and at F4 50% there is Very strong inhibition power is greater than the positive control, which is 40 mm.Conclusion: Antiseptic made from natural ingredients a combination of Betel, Lime, and Bundung Leave at a concentration of 40% has the same antiseptic effectiveness as antiseptic with synthetic chemical substances. This polyherbal antiseptic can be used for the purposes of nursing and midwifery action.Keywords: Betel leaf-lime peel-bundung plant, antiseptic, nursing and obstetrics measures
Uji Aktivitas Antiseptik Ekstrak Etanol Tanaman Bundung (Scirpus grossus L.) Terhadap Penyembuhan Luka Sayat pada Tikus Putih (Rattus norvegicus) Amalia, Ghina Rezki; Saftia Aryzki; Darini Kurniawati
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 2 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i2.531

Abstract

Bundung Plant (Scirpus grossus L.) is one of the wild plants that is very easy to get, but not many people know its properties. This plant is empirically used by the community as a wound treatment and antimicrobial. This plant is proven to contain several compounds such as tannins, flavonoids, phenolics, saponins, steroids and terpenoids. This study aims to determine the antiseptic activity of ethanol extract of Bundung Plant with various concentrations and the most effective concentration in healing white rat incision wounds (Rattus norvegicus). the method used begins with the extraction process, making extract concentrations, preparing test animals, dividing test animal groups, treating test animals, observing the healing phase and testing antiseptic activity. The results of the group test on the measurement of the average length and healing time of the incision wound, the wound that closed the fastest was the 4% extract group which was seen clinically could be distinguished by its healing speed, from the results of the analysis there was no significant difference in the healing time span and measurement of the average length of the incision wound. The conclusion of this study is that the ethanol extract of the Bundung Plant (Scirpus grossus L.) has antiseptic activity on the healing of incision wounds of white rats (Rattus norvegicus) which is observed through the healing time span and there is no significant difference in changes in wound healing time and the length of the incision wound in the five groups and the most optimal concentration of ethanol extract of the Bundung Plant (Scirpus grossus L.) with the concentration of the extract observed clinically is 4%.
Co-Authors Iwan Yuwindry Kunti Nastiti MARIA BINTANG Noval Noval Saftia Aryzki Saftia Aryzki Sariyasih Sariyasih Shofia Rahmi Shofia Rahmi