Article Per Year (5 Year)
p-Index From 2020 - 2025
2.583
P-Index
This Author published in this journals
All Journal Sainteks CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Sains Dasar Jurnal Kimia Riset Al-Kimia Walisongo Journal of Chemistry AL-ULUM: JURNAL SAINS DAN TEKNOLOGI Fullerene Journal of Chemistry Stannum : Jurnal Sains dan Terapan Kimia SPIN: Jurnal Kimia & Pendidikan Kimia Jurnal Manajemen, Ekonomi, Hukum, Kewirausahaan, Kesehatan, Pendidikan dan Informatika (MANEKIN)
Dwi Fitri Yani
Universitas Islam Negeri Raden Fatah Palembang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology

Published : 17 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 17 Documents
Search

 1   2 
Uji Aktivitas Antiinflamasi Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Penghambatan Denaturasi Protein Dheani Sepalia Novika; Riska Ahsanunnisa; Dwi Fitri Yani
Stannum : Jurnal Sains dan Terapan Kimia Vol 3 No 1 (2021): April 2021
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v3i1.2117

Abstract

Inflammation is a cell breakdown caused by bacteria, chemical substances, mechanical trauma and physical trauma. Testing of such anti-inflammatory activity can be done in-vitro with the method of protein denaturation using natural materials starfruit leaf (Averrhoa Oxalidaceae L.). This research aims to determine the comparison of the activity of ethanol extract in the strafruit leaf and sodium diclofenac. strafruit Leaf Ethanol extract is made with a concentration of 1 ppm, 10 ppm and 100 ppm with the comparator of sodium diclofenac. Antiinflammatory resistance is obtained by calculating the percentage of inhibition of protein denaturation. The result of a test of strafruit leaf ethanol extract (Averrhoa Oxalidaceae L.) with a value of IC50 of 20.20 μg/mL indicates an inhibitory percentage of more than 20% at the lowest concentration of 1 ppm, while IC50 sodium diclofenac of 14.93 μg/mL with an inhibitory percentage of more than 20% at 5 ppm .
UJI TOKSISITAS EKSTRAK ETANOL DAUN KERAI PAYUNG (Filicium decipiens) DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT) Dwi Fitri Yani; Navinda Ramadan; Rina Athiah; Ana Maghpiroh; Tri Sunarsih
SPIN JURNAL KIMIA & PENDIDIKAN KIMIA Vol. 5 No. 1 (2023): Januari - Juni 2023
Publisher : UIN Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/spin.v5i1.6676

Abstract

Kerai payung (Filicium decipiens) merupakan tanaman yang berasal dari Asia tropis dan Afrika, yang saat ini juga terkenal di berbagai daerah di Indonesia salah satunya di pulau Sumatera. Selain memiliki manfaat sebagai tanaman peneduh juga terdapat beberapa metabolit sekunder yang terkandung didalamnya. Metabolit sekunder dapat dimanfaatkan dalam bidang lingkungan, pertanian, kesehatan dan menjadi bahan makanan. Penelitian ini bertujuan untuk mengetahui aktivitas toksik ekstrak etanol daun kerai payung (Filicium decipiens) terhadap Artemia salina Leach menggunakan metode Brine Shrimp Lethality Test (BSLT). Hasil uji fitokimia ekstrak etanol daun kerai payung positif mengandung senyawa flavonoid, tanin, dan saponin. Uji toksisitas daun kerai paying memiliki nilai LC50 sebesar 456,022 ppm. Aktivitas toksisitas ekstrak etanol daun kerai payung (Filicium decipiens) dengan BSLT toksik untuk digunakan sebagai antikanker karena memiliki nilai LC50 < 1000 ppm.
Penerapan Strategi Pembelajaran Problem Based Learning Terhadap Kemampuan Kreatif Peserta Didik Dwi Fitri Yani; Siti Tiara Maulina
Jurnal Manajemen, Ekonomi, Hukum, Kewirausahaan, Kesehatan, Pendidikan dan Informatika Vol 1 No 03 : Maret (2023): Jurnal Manajemen, Ekonomi, Hukum, Kewirausahaan, Kesehatan, Pendidikan d
Publisher : Shofanah Media Berkah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Source power human that quality tall Marked with Skills Management, use and Develop power thinkwrong Only think creative. Development Skills think creative Needed to help solve problem and look for alternative Solving problem. Ability think creative will become food Later Face Various Problems that exist, Especially In the era of globalization. Attempt that get Done Strengthening ability think creative Done through education. Purpose research .ini be to know Application Strategy Learning Problem Based Learning Towards Ability Creative Participants Educate. Method research that Used Descriptive Qualitative with Engineering Collection data Study Library with read and Analyze Articles, journalsand book. PBL Viewed as type Learning that can Increase ability think level tall or ability think creative. Ability think creative Influenced by encouragement internal and External. Personality and Background back culture somebody get affect attempt somebody to think creative towards one problem life. With Learning Based Problem Based Learning Expected teacher or lecturer become facilitator best for Participants educate and studentsand student Expected can Communicate with good and think creative deep Settlement problem Keywords: Think creatively, Problem Based Learning
Skrining Fitokimia Dan Uji Sun Protection Factor (SPF) Ekstrak Daun Sungkai (Peronema Canescens Jack) Secara In Vitro La Mardani Putra; Dwi Fitri Yani; Muhammad Faturrizqi; Putri Rahayu; Osyellah Indar Parawansya
Jurnal Kimia Fullerene Vol 8 No 2 (2023): Fullerene Journal of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37033/fjc.v8i2.490

Abstract

Sungkai leaves have bioactive compounds in the form of triterpenoids, alkaloids, flavonoids, phenolics, steroids and saponins. This compound contains a chromophore group (conjugated single double bond) which is able to absorb ultraviolet light thereby reducing radiation to the skin. The higher the value, the better it is used as a sunscreen. The purpose of this study was to determine the results of the phytochemical test of the ethanol extract of Sungkai leaves (Peronema Canescens Jack) and the Sun Protection Factor (SPF) test of the ethanol extract of Sungkai leaves (Peronema Canescens Jack) in vitro. The SPF values ​​produced at concentrations of 100, 200, 300, 400, and 500 ppm in ethanol extraction were 7.51; 15.93; 27.40; 34.87; and 39.86. Sungkai Leaf Extract (Peronena Cenescens Jack) can be used as a sunscreen ingredient, at concentrations of 200 ppm, 300 ppm, 400 ppm it is included in the suntan category (moderate to ultra protection) and in this SPF test the concentration will affect the resulting SPF value.
Studi In Silico Enam Senyawa dari Caesalpinia bonduc L. (Robx) untuk Prediksi Toksisitas dan Interaksi pada Reseptor 5JMY sebagai Inhibitor Enzim Elastase Desi Nadya Aulena; Dwi Fitriyani
Sainteks Vol 19, No 2 (2022): Oktober
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/sainteks.v19i2.13532

Abstract

Biji buah kebiul (Caesalpinia bonduc L. Roxb) memiliki kandungan senyawa caesalpinianone, 6-O-caesalpinianone, 2-O-β-δ-glucosyloxy-4-methoxy benzene propanoic acid, ethacrynic acid, bonducellin, dan flavonol. Senyawa ini diketahui berpotensi sebagai antioksidan dan dapat dimanfaatkan sebagai antiaging. Data menunjukkan belum ada kajian terkait senyawa yang menghambat kinerja enzim elastase, sehingga pada penelitian ini akan dikaji terkait senyawa yang berperan dalam penghambatan aging melalui studi skrining virtual dan elusidasi mode ikatan pada beberapa struktur kristal enzim elastase dengan metode molecular docking. Untuk memperkirakan toksisitas dan interaksi dengan reseptor 5JMY, telah dilakukan studi in silico menggunakan aplikasi online pkCSM dan Molegro Virtual Docker (MVD) dengan protein kode pdb 5JMY. Hasil studi menunjukkan bahwa bahwa enam senyawa ini tidak toksik dan baru menimbulkan efek samping pada dosis yang lebih tinggi dari log dosis 3,964 mg/kg BB/hari. Interaksi tiga senyawa yaitu caesalpinianone, 6-O-caesalpinianone dan ethacrynic acid dengan reseptor 5JMY lebih besar daripada kontrol positif ECGC. Senyawa 6-O-caesalpinianone memiliki aktivitas paling tinggi dibandingkan dengan 5 senyawa senyawa aktif dari Caesalpinia bonduc L. (Robx) lainnya dan lebih tinggi dari pada ECGC. Asam amino yang terlibat dalam interaksi dengan caesalpinianone, 6-O-caesalpinianone, 2-O-β-δ-glucosyloxy-4-methoxybenzenepropanoic acid dan bonducellin adalah Arg 717. Asam amino yang terlibat dalam interaksi dengan senyawa ethacrynic acid dan flavonol adalah His 583 dan Met 579.
A Comparison of Anti-inflammatory Activity of Ethanol Extracts of Young and Old Areca Seeds (Areca catechu L.) in vitro Leni Legasari; Ambar Wati; Dwi Fitri Yani
Stannum : Jurnal Sains dan Terapan Kimia Vol 5 No 2 (2023): Oktober 2023
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v5i2.4376

Abstract

Areca catechu L. has been widely used as a traditional medicine in medicinal practices in various countries around the world. Areca nut contains secondary metabolite compounds such as alkaloids, flavonoids, triterpenoids, steroids, and tannins so it has great potential to be developed as a medicine. The use of anti-inflammatory drugs from natural ingredients is widely developed because synthetic non-steroidal anti-inflammatory drugs cause side effects to the body such as nausea, diarrhea, headaches, and stomach ulcers. This study aims to determine the content of secondary metabolites and determine the anti-inflammatory activity of ethanol extracts of young and old areca nut seeds. Old areca nut seeds used are areca nut fruits that have an orange color while young areca nut seeds are areca nut fruits that have a green color. The anti-inflammatory activity test method was carried out using the protein denaturation inhibition method at 5, 10, 15, and 20 ppm extract concentrations. The results of this study indicate that young and old areca nut seeds positively contain alkaloids, flavonoids, tannins, and saponins and negatively contain steroids. The results of anti-inflammatory activity testing show that ethanol extracts of young and old areca nut seeds have the potential as anti-inflammatory because they have a percentage value of protein denaturation inhibition greater than 20%. A comparison of anti-inflammatory activity between areca nut seeds can be seen from the IC50 value of ethanol extract. The IC50 results show that young areca seeds have an IC50 value of 7.42 ppm which is higher than the old areca seeds of 11.52 ppm
Phytochemical Test and Sunscreen Activities Ethanol Extract of Guava Tangkalak Leaves (Belluciapentamera) Cahya, Oktania; Dwi Fitri Yani; Muhammad Rayhan; Ayu Wandira; Desi Yana Sari; Rini Handayani; Mega Retha Sefriany
Al-Kimia Vol 12 No 2 (2024): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v12i2.50399

Abstract

One of the most important sources of natural light for life is sunlight, and the skin is the outermost and most significant organ in the human body, making it vulnerable to sunlight exposure. This study aims to determine the biochemistry of secondary metabolite compounds in the guava tangkalak leaves of the plant and their activities as an active ingredient of sunscreen using UV-Vis spectrophotometry. The results of this study indicate that the guava tangkalak leaves plant contains secondary metabolite compounds, such as flavonoids, alkaloids, tannins, saponins, and steroids. The SPF values produced at concentrations of 400, 500, 600, 700, 800, and 1000ppm, SPF values of 2.96, 4.60, 7.70, 10.76, 15.13, and 27.41. The maximum concentration of 1000 ppm protects ultra-categories in SPF.
Co-Authors Ade Oktasari Ambar Wati Ana Maghpiroh AYU WANDIRA Cahya, Oktania Damayanti Iskandar Dany Raihan Derys Ruwandha Desi Nadya Aulena Desi Yana Sari Dheani Sepalia Novika Fitri Oviyanti La Mardani Putra Leni Legasari Mega Retha Sefriany Muhammad Faturrizqi muhammad hernanda MUHAMMAD RAYHAN Muhammad Salman Alfarisi Navinda Ramadan Novita Sari Osyellah Indar Parawansya Popi Rantina Putri Rahayu Raden Fatahillah Raden Fatahillah Rahmawati Tri Yuni Reynaldi Reynaldi Rina Athiah Rini Handayani Rio Dirmansyah Riska Ahsanunnisa Siti Tiara Maulina Suci Permata Sari Tri Sunarsih