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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN
Andriana Tjitria Widi Wardani
Bagian Ilmu Telinga Hidung Tenggorok FK UNISSULA, Semarang
Health Professions Medicine & Pharmacology

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Quality of Life Allergic Rhinitis after Probiotic Combination Supplementation Wardani, Andriana Tjitria Widi; Soetoko, Anita Soraya
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 4, No 2 (2012): Juli-Desember 2012
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.385 KB) | DOI: 10.30659/sainsmed.v4i2.372

Abstract

Background: Probiotics are potential as a therapy for allergy sufferers, which can increase the ratio IFNã, IL4. However, the effects of probiotics on the quality of life of patients with allergic rhinitis have not been developed yet. This study aimed to determine the effect of a combination of probiotics on the quality of life of patients with allergic rhinitis.Design and Methods: This study used a randomized design with post test control group design. The populations in this study were men and women aged 18-25 years who suffer from allergic rhinitis with moderate to severe according to the WHO criteria. This study uses two groups: the group treated by administration of a combination of probiotics and the control group were given a placebo. Quality of life was assessed by checklist scores and levels of IgE. Data were analyzed using the Mann Whitney U test with 95% confidence intervals.Results: The results of statistical analysis showed no significant difference between the quality of life of allergic rhinitis sufferers control and treatment groups (p> 0.05). However, there are significant differences between the mean levels of IgE allergy sufferers rhintis control and treatment groups (p <0.05).Conclusion: Probiotic treatment did not affect the quality of life of patients with allergic hinitis but a reduction in the levels of IgE (Sains Medika, 4(2):157-164).
Effect of nasal irrigation on eosinophil and recurrence in allergic rhinitis Sulistyanto, Agung; Wardani, Andriana Tjitria Widi; Maharani, Virgi Mayang
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.31474

Abstract

Until now, the treatment of allergic rhinitis has not been satisfactory. Patients with allergic rhinitis are highly dependent on medical pharmacological treatment. Nasal irrigation is expected to help reduce symptoms due to decreased eosinophil counts and recurrence of allergic rhinitis. This study aims to determine the effect of nasal irrigation on eosinophils and the recurrence of allergic rhinitis—experimental research by pre – post-test group design. Twenty samples of allergic rhinitis patients were trained to wash their nose once a day at home—nasal mucosal secretion was collected to count eosinophils before and after intervention. The degree of recurrence was assessed based on the symptoms of nasal congestion, runny nose, sneezing, and itchy nose. The degree is divided into three groups: decrease, remain, and increase. The statistical analysis used in this study for bivariate analysis was Wilcoxon Test. There was a significant decrease in eosinophil count (p = 0.00) and recurrence of nasal congestion (p = 0.00), runny nose (p = 0.00), sneezing (p = 0.001) and itchy nose (p = 0.00) in allergic rhinitis after nasal irrigation intervention. Nasal irrigation treatment can help decrease eosinophil count and recurrence of allergic rhinitis.
Co-Authors Agung Sulistyanto Anita Soraya Soetoko Maharani, Virgi Mayang