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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Amerta Nutrition Journal of Advanced Multidisciplinary Research Jurnal Pengabdian Masyarakat Kedokteran
Anita Soraya Soetoko
Bagian Ilmu Anatomi FK UNISSULA, Semarang
Religion Aerospace Engineering Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Earth & Planetary Sciences Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Quality of Life Allergic Rhinitis after Probiotic Combination Supplementation Wardani, Andriana Tjitria Widi; Soetoko, Anita Soraya
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 4, No 2 (2012): Juli-Desember 2012
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.385 KB) | DOI: 10.30659/sainsmed.v4i2.372

Abstract

Background: Probiotics are potential as a therapy for allergy sufferers, which can increase the ratio IFNã, IL4. However, the effects of probiotics on the quality of life of patients with allergic rhinitis have not been developed yet. This study aimed to determine the effect of a combination of probiotics on the quality of life of patients with allergic rhinitis.Design and Methods: This study used a randomized design with post test control group design. The populations in this study were men and women aged 18-25 years who suffer from allergic rhinitis with moderate to severe according to the WHO criteria. This study uses two groups: the group treated by administration of a combination of probiotics and the control group were given a placebo. Quality of life was assessed by checklist scores and levels of IgE. Data were analyzed using the Mann Whitney U test with 95% confidence intervals.Results: The results of statistical analysis showed no significant difference between the quality of life of allergic rhinitis sufferers control and treatment groups (p> 0.05). However, there are significant differences between the mean levels of IgE allergy sufferers rhintis control and treatment groups (p <0.05).Conclusion: Probiotic treatment did not affect the quality of life of patients with allergic hinitis but a reduction in the levels of IgE (Sains Medika, 4(2):157-164).
Pengaruh Kombinasi Ekstrak Belimbing Wuluh (Averrhoa Bilimbi L.) dan Ekstrak Kunyit (Curcuma Longa L.) terhadap Kadar Low Density Lipoprotein: Effect of Combination of Averrhoa Bilimbi Extract and Curcuma Longa Extract on Low Density Lipoprotein Levels in Rats Fed a High Fat Diet Fatikhasari, Amalia Nurazima; Yuniarifa, Conita; Utami, Kamilia Dwi; Riza, Mohamad; Soetoko, Anita Soraya
Amerta Nutrition Vol. 8 No. 3 (2024): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v8i3.2024.363-367

Abstract

Background: Hypercholesterolemia is a state of total blood cholesterol levels transported by LDL exceeding normal limits. As a result, it can clog blood vessels, and this condition is a risk factor for CHD. Alternative medicine includes flavonoids in Averrhoa bilimbi (belimbing wuluh) known to reduce cholesterol and LDL levels, and curcumin in turmeric known to reduce fat absorption and increase fat excretion. Objectives: The aim of this study was to analyze the combined effect of bilimbi fruit and turmeric extracts on LDL levels. Methods: This experimental research used post-test only with a control group design involving male Wistar rats divided into 6 (six) random groups. Group KN (standard feed, aquadest for 28 days), K- (high-fat feed for 14 days, followed by standard feed and aquadest), K+ (high-fat feed for 14 days, followed by standard feed, aquadest, and simvastatin 0.18mg/200 g BW/day), P1 (high-fat feed for 14 days, followed by standard feed, aquadest and extracts of bilimbi fruit and turmeric extract at a dose of 240: 270 mg/200 g BW/day), P2 (high-fat diet for 14 days, followed by standard feed, distilled water and bilimbi fruit and turmeric extract at a dose of 360: 175 mg/200 g BW/day), P3 (high-fat diet for 14 days, followed by standard feed, distilled water and extracts of bilimbi fruit and turmeric at a dose of 120: 405 mg/200 g BW/day). The determination of LDL levels was done through a direct method using a spectrophotometer with a wavelength of 550 nm. Results: The mean LDL levels were KN (53.60 ± 10.69) mg/dL, K- (193.40 ± 16.86) mg/dL, K+ (100.20 ± 42.48) mg/dL, P1 (118.00 ± 64.71) mg/dL, P2 (104.00 ± 45.28) mg/dL, P3 (78.00 ± 4.69) mg/dL. The data received was analyzed using the Kruskal-Wallis test. Then, the results obtained differences in LDL levels between various groups (p<0.001). Subsequently, it was continued with the Mann-Whitney test on KN compared to K-, K+, P1, P2, P3 indicating p=0.009. As a result, it was found a significant difference in LDL levels between KN and K-, K+, P1, P2, and P3. Conclusions: This research concludes that providing a mixture of bilimbi fruit extract and turmeric extract can reduce LDL levels.
Relationship between Level of Test Anxiety and Module Score in Medical Students: An Analytical Observational Study Aryati, Salsabila; Hastuti, Rizkie Woro; Soetoko, Anita Soraya
Journal of Advanced Multidisciplinary Research Vol 5, No 2 (2024): December 2024
Publisher : Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/jamr.5.2.126-132

Abstract

Modul score are scores obtained from theoretical exams in the form of MCQ (Multiple Choice Questions) which have a large portion in determining graduation. The achievement of module scores can be influenced by many factors, one of which is the level of anxiety. Anxiety during exams is known to inhibit cognitive function which affects performance during exams so that it can affect the results obtained. This study aims to determine the relationship between the level of anxiety and the value of the mental health problem module in FK Unissula students class of 2021. This study is an observational study with a cross-sectional research design conducted at the Faculty of Medicine, Universitas Islam Sultan Agung. Respondents were asked to complete the Nist and Diehl Test Anxiety Questionnaire questionnaire consisting of 10 questions. The data obtained were analyzed with the spearman correlative test to determine the meaning and strength of the relationship between anxiety levels and module scores. The results of the study from 140 samples found that most students who were not anxious got good grades with a percentage of 63.1%, students who were mildly anxious the majority got enough scores with a percentage of 36.2% and students who were severe anxious about the majority got less scores with a percentage of 56%. The results of the bivariate analysis test using the spearman correlative test obtained a p value of 0.000 (p < 0.05). The correlation coefficient between anxiety levels and module scores was 0.391. The level of anxiety significantly affects the value of the mental health problem module in FK UNISSULA students batch 2021 with weak correlation strength.
Membangun Kewaspadaan Munculnya Komplikasi Neuropati Perifer pada Gangguan Metabolik di Lingkungan Klinik Pratama Soetoko, Anita Soraya; Fatmawati, Dina
Jurnal Pengabdian Masyarakat Kedokteran Vol 4, No 1 (2025): Januari
Publisher : Fakultas Kedokteran, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/abdimasku.4.1.25-32

Abstract

Gangguan metabolik merupakan salah satu penyakit kronis yang banyak dijumpai di Klinik Pratama. Komplikasi yang umum dijumpai pada penyakit ini berupa neuropati perifer. Membangun kewaspadaan melalui peningkatan pengetahuan dan kegiatan deteksi dini terhadap neuropati perifer pada penderita gangguan metabolik dapat mencegah penurunan kualitas hidup penderita akibat komplikasi ini. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan dan deteksi dini neuropati perifer pada penderita gangguan metabolik di Klinik Pratama. Kegiatan ini dilakukan dengan metode penyuluhan mengunakan media power point (PPT) dan pemeriksaan gejala dan tanda neuropati perifer menggunakan tes Michigan dan monofilamen. Kegiatan ini dihadiri oleh 38 peserta yang berasal dari 2 Klinik Pratama di Semarang. Hasil evaluasi setelah selesai kegiatan penyuluhan, didapatkan 70% peserta memiliki pengetahuan yang baik tentang definisi dan mekanisme, 90% mengetahui tanda dan gejala, serta 100% peserta memahami cara mencegah terjadinya neuropati perifer. Hasil tes Michigan, didapatkan 13 peserta memiliki gejala subjektif dan 4 peserta memiliki tanda objektif neuropati perifer, sedangkan pada hasil tes monofilamen didapatkan 5 peserta terdiagnosis neuropati perifer dan 7 memiliki risiko tinggi dalam kurun waktu 4 tahun ke depan. Kegiatan ini menunjukan kemanfaatannya dalam meningkatkan pengetahuan dan mampu mendeteksi dini gejala neuropati perifer pada penderita gangguan metabolik di Klinik Pratama.Metabolic disorders are one of the chronic diseases commonly found in primary clinics. The common complication found in this disease is peripheral neuropathy. Building awareness through increased knowledge and early detection for peripheral neuropathy in patients with metabolic disorders can prevent a decline in the quality of life of patients. The aim of this activity is to enhance knowledge and early detection of peripheral neuropathy in patients with metabolic disorders at the primary clinic. This activity was conducted by giving health education using PowerPoint (PPT) media and examination of peripheral neuropathy symptoms and signs using the Michigan test and monofilament. This activity was attended by 38 participants from 2 primary clinics in Semarang. The evaluation results after giving health education showed that 70% of the participants had a good understanding of the definition and mechanism, 90% knew the signs and symptoms, and 100% of the participants understood how to prevent peripheral neuropathy. The results of the Michigan test showed that 13 participants had subjective symptoms and 4 participants had objective signs of peripheral neuropathy, while the results of the monofilament test indicated that 5 participants were diagnosed with peripheral neuropathy and 7 were at high risk within the next 4 years. This activity demonstrates its usefulness in increasing knowledge and being able to detect early symptoms of peripheral neuropathy in patients with metabolic disorders at the primary clinic.
Penyuluhan bagi Kader PKK Desa Banjardowo tentang Potensi Tanaman Kemangi (Ocinum Sanctum Linn) terhadap Kesehatan Sumarawati, Titiek; Chodidjah, Chodidjah; Widayati, Eni; Soetoko, Anita Soraya
Jurnal Pengabdian Masyarakat Kedokteran Vol 3, No 1 (2024): Januari
Publisher : Fakultas Kedokteran, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/abdimasku.3.1.33-38

Abstract

Tanaman Daun Kemangi (Ociumum sanctum Linn) mengandung banyak senyawa aktif seperti golongan alkaloid, terpenoid, fenolik, saponoid, tannin dan flavonoid yang terbukti mempunyai aktivitas sitotoksik, serta memiliki kadar nilai IC50 pada sel MCF-7 sebesar 6,95 µg/ml. Selain itu juga terbukti bahwa ekstrak etanol kemangi mempunyai aktivitas antioksidan yang sangat kuat. Tujuan pengabdian masyarakat ini adalah untuk mensosialisasikan terkait dengan hasil penelitian mengenai kandungan zat aktif dalam tanaman kemangi yang mempunyai potensi terhadap Kesehatan. Kelurahan banjardowo merupakan desa binaan Fakultas kedokteran universitas islam sultan Agung sehingga lokasi ini dipilih untuk mensosialisasikan hasil penelitian tentang tanaman kemangi mengingat banyaknya manfaat bagi Kesehatan dan meningkatkan pengetahuan ibu ibu. Metode penyuluhan yang digunakan adalah Metode ceramah dan diskusi kelompok, para ibu ibu kader PKK kelurahan BanjarDowo yang mengikuti penyuluhan sebanyak 23 orang, usia 41- 60 tahun sebanyak 16 orang dan usia 25 – 40 tahun sebanyak 7 orang. Hasil analisis nilai pretest dan postest peserta menunjukan terdapat kenaikan nilai rerata peserta pada postest, yaitu 6,70±1,8, dimana sebelum kegiatan penyuluhan dimulai nilai rerata peserta hanya mencapai angka 4,78±1,9. Dari analisis statistik menunjukan adanya perbedaan yang bermakna antara nilai pretest dan postest peserta dengan nilai p=0,000. Dengan pemberian penyuluhan pada kader PKK di kelurahan Banjardowo tentang potensi tanaman kemangi terhadap Kesehatan menunjukkan hasil adanya nilai peningkatan pengetahuan peserta sebelum diberi penyuluhan dan sesudah penyuluhan.The basil leaf plant (Ociumum sanctum Linn) contains many active compounds such as alkaloids, terpenoids, phenolics, saponoids, tannins and flavonoids which have been proven to have cytotoxic activity, and have an IC50 value in MCF-7 cells of 6.95 µg/ml. Apart from that, it has also been proven that basil ethanol extract has very strong antioxidant activity. The aim of this community service is to disseminate research results regarding the content of active substances in basil plants which have potential for health. Banjardowo sub-district is a village supported by the Faculty of Medicine, Sultan Agung Islamic University, so this location was chosen to disseminate the results of research on basil plants considering the many benefits for health and increasing mothers' knowledge. The counseling method used was the lecture and group discussion method, 23 people from PKK cadres from BanjarDowo sub-district took part in the counseling, 16 people aged 41-60 years and 7 people aged 25-40 years. The results of the analysis of participants' pretest and posttest scores showed that there was an increase in the participants' average score on the posttest, namely 6.70 ± 1.8, where before the counseling activities began, the participants' average score only reached 4.78 ± 1.9. Statistical analysis shows that there is a significant difference between the participants' pretest and posttest scores with a p value = 0.000. By providing counseling to PKK cadres in the Banjardowo sub-district about the potential of basil plants for health, the results showed that there was a value in increasing participants' knowledge before being given the counseling and after the counseling.
Tingkat Pengetahuan Penyakit Diabetes Mellitus pada Lansia Peserta BPJS di Klinik Mugi Sehat Jatingaleh Semarang Chodidjah, Chodidjah; Sumarawati, Titiek; Soetoko, Anita Soraya
Jurnal Pengabdian Masyarakat Kedokteran Vol 3, No 1 (2024): Januari
Publisher : Fakultas Kedokteran, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/abdimasku.3.1.1-5

Abstract

Diabetes mellitus (DM) merupakan penyakit degeneratif atau gangguan metabolisme kronis dengan multi etiologi yang ditandai dengan tingginya kadar gula darah disertai dengan gangguan metabolisme karbohidrat, lipid dan protein sebagai akibat insufisiensi insulin. Klinik Mugi Sehat Jatingaleh merupakan klinik yang melayani peserta BPJS dan tiap bulan dilakukan kegiatan penyuluhan kesehatan bagi lansia penderita Diabetes Mellitus, maka masyarakat lansia peserta BPJS di klinik Mugi Sehat Jatingaleh perlu diberi penyuluhan tentang. Mengenal penyakit Diabetes Mellitus. Metode Penelitian 26 peserta BPJS di Klinik Mugi Sehat Jl. Jatingaleh Semarang sebagai responden dilakukan pretest sebelum diberi penyuluhan post tes setelah penyuluhan, untuk mengetahui tingkat pengetahuan tentang pentingnya pengetahuan penyakit Diabetes Mellitus bagi lansia peserta BPJS di Klinik mugi Sehat Jatingaleh Semarang serta di bagi leaflet untuk belajar menghitung kebutuhan kalori. Hasil pemahaman peserta meningkat setelah di berikan penyuluhan. Kesimpulan Peserta BPJS Lansia yang menderita Diabetes Mellitus memahami dan dapat menghitung kebutuhan kalori untuk mengontrol kadar gula darah.Diabetes mellitus (DM) is a degenerative disease or chronic metabolic disorder with multiple etiologies characterized by blood sugar levels accompanied by metabolic, lipid and protein disorders as a result of insulin insufficiency. Mugi Sehat Jatingaleh Clinic is a clinic that serves BPJS participants and every month health counseling activities are carried out for the elderly with Diabetes Mellitus, so the elderly people who are BPJS participants at the Mugi Sehat Jatingaleh clinic need to be given counseling about. Knowing Diabetes Mellitus. Research Methods 26 BPJS participants at the Mugi Sehat Clinic Jl. Jatingaleh Semarang as a respondent did a pretest before being given counseling after counseling, to determine the level of knowledge about the importance of knowledge about Diabetes Mellitus for the elderly BPJS participants at the Mugi Sehat Clinic Jatingaleh Semarang and distributed leaflets to learn to calculate calorie needs. The results of participants' understanding increased after being given counseling. Conclusion BPJS Elderly participants who suffer from Diabetes Mellitus understand and can calculate calorie needs to control blood sugar levels.
Co-Authors Andriana Tjitria Widi Wardani Aryati, Salsabila Chodidjah Chodidjah Dina Fatmawati Eni Widayati Fatikhasari, Amalia Nurazima Hastuti, Rizkie Woro Riza, Mohamad Titiek Sumarawati Utami, Kamilia Dwi Yuniarifa, Conita