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All Journal World Nutrition Journal Majalah Anestesia & Critical Care (MACC) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Wahyu Ika Wardhani
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Medicine & Pharmacology Public Health

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Natural Evolution of Regurgitation in Children Aged 12-24 Months: A 1-year Cohort Study Badriul Hegar; Fatima Safra Alatas; Muzal Kadim; Nina Dwi Putri; Wahyu Ika Wardhani
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 1, April 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (326.871 KB) | DOI: 10.24871/141201313-18

Abstract

Background: There are very limited cohort studies regarding long term outcome of gastroesophageal reflux diseases (GERD), especially until 24 months old. The aim of this study is to see the natural history of GERD in12-24 months old children based on their clinical signs and symptoms.Method: Prospective one year population base cohort study involving 262 children. Their regurgitation history and GERD symptoms were recorded every two months.Results: Two hundred and  fivety three children completed the study. Seventy three children (27.8%) were still having regurgitation when they were 6 months old, 44 (16.7%) until 9 months old, and 24 (9.2%) until 12months old. During 12 months follow-up the prevalence and frequency of regurgitation decreased to 2.4% and 1.2% in the age of 18 and 24 months respectively. Infant with regurgitation at 6 months old were 13.2 times more likely to have regurgitation at 12 months old (RR = 13.2; 95% CI = 4.8-36.6). Prevalence of regurgitation after 18 months old were 37 times higher risk compared to those not regurgitating at the age of 12 months (RR = 37; 95% CI = 2.2–613.9). GERD symptoms were higher in children that were still regurgitating until 9 months old 64.5% (RR = 2.3; 95% CI = 1.7-3.0) compared to those only experiencing until 6 months old 54.7% (RR = 1.3; 95% CI = 1.7-3.0).Conclusion: Regurgitation decrease during 12-24 months old period. The history of regurgitation in 6 and 9 months old is related to the probability to become GERD in 12-24 months old period. Keywords: gastroesophageal reflux, children 12-24 months, GERD symptoms
Olive Oil and Vegetable Extract in Modified Hospital Enteral Formula Improves Glycemic Variability in Critically-Ill Diabetic Ketoacidosis Obese Patient: A Case Report Anindhita, Bintari; Singal, Anna Maurina; Wardhani, Wahyu Ika; Manikam, Nurul Ratna Mutu; Aditianingsih, Dita
Majalah Anestesia & Critical Care Vol 42 No 1 (2024): Februari
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif (PERDATIN) / The Indonesian Society of Anesthesiology and Intensive Care (INSAIC)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55497/majanestcricar.v42i1.315

Abstract

Background: Severe hyperglycemia in diabetic ketoacidosis may elevate pro inflammatory cytokines, oxidative stress, and metabolic disruptions, impacting the nutritional status of critically ill patients. Diabetes-specific formula (DSF) administration is linked to favorable glycemic control, but research on the role of modified hospital enteral formulas in diabetic critical illness is lacking. Case Description: An obese 29-year-old male at risk of malnutrition, presented to the emergency room with decreased level of consciousness due to metabolic encephalopathy, diabetic ketoacidosis due to suspected type 1 diabetes mellitus, hypertension, and acute kidney injury. Medical nutritional therapy was provided via enteral route according to recent ESPEN, ASPEN and ADA recommendation. The administered enteral formula was a modified hospital-based enteral formula, consisting of a special kidney hospital-based enteral formula mixed with olive oil as source of monounsaturated fatty acid (MUFA) and vegetables as source of fibers. During the first week of hospitalization, the patient’s coefficient of variation (%CoV) of glycemic variability ranged between 17–61%, in addition, at the beginning of the second week of treatment there was also an increase in glycemic variability to 53%. This could be influenced by several factors. However, improvement in glycemic variability was observed in the following days. This improvement was in line with the gradual increase in MUFA and fiber intake, which reached its highest intake during the second week of hospitalization. Conclusion: Hospital-based enteral formula modified with olive oil and vegetable extract can be made to resemble the nutrients composition of diabetes specific formula and has a favorable effect on glycemic variability.
Leucine-included liquid diet as medical nutrition therapy improved handgrip strength and mid-upper circumference in clinically malnourished pulmonary tuberculosis patient with high neutrophil lymphocyte ratio: A case report from Universitas Indonesia hospital Singal, Anna Maurina; Afifa, Nadhira Nuraini; Wardhani, Wahyu Ika; Baskoro, Hario
World Nutrition Journal Vol. 8 No. i2 (2025): Volume 08 Issue 2, February 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i2.0005

Abstract

Background and objectives: Muscle weakness delays clinical improvement in pulmonary tuberculosis patients. Higher neutrophil lymphocyte ratio, low handgrip strength, mid-upper arm circumference indicates bad clinical outcome. Weight loss must be managed from the start of treatment. Good muscle condition has benefits to the recovery rate. Leucine provides benefits in increasing the synthesis of muscle mass so as the clinical conditions. Unfortunately, leucine has not been the routine part of medical nutrition therapy in tuberculosis patients. Methods: This is a case report of a female patient with body weight 42 kg and height 150 cm, admitted to Universitas Indonesia Hospital, with lung tuberculosis. Leucine given, started from 1.95 g/day to the maximum amount of 7,34 g/day through the hospital tailored-made liquid food. There was an improvement of clinical signs and symptoms during 14 days of hospitalization. Mid-upper arm circumferences at day 1, 8, and 15 were 21.1, 21.4, and 12.9 21.9 cm in a row. The right and left handgrip strength at day 1, 8, and 15 were 9.7 kg and 8.1 kg, 10.9 kg and 8.9 kg, 15.1 kg and 13.4 kg, respectively. While the neutrophil lymphocyte ratio at day 0, 6, and 9 were increasing, at 6.89, 6.89, and 13.8, in a row. Conclusions: Leucine 1.95–7.34 g/day, in tailored-made liquid food, as part of tuberculosis management therapy, though the NLR 13.8, can improve the mid-upper arm circumference, handgrip strength, clinical signs and symptoms in 14 days of hospitalization.
Co-Authors Afifa, Nadhira Nuraini Anindhita, Bintari Badriul Hegar Badriul Hegar Baskoro, Hario Dita Aditianingsih Fatima Safra Alatas Muzal Kadim Nina Dwi Putri Nurul Ratna Mutu Manikam Singal, Anna Maurina