Ivan R. Widjaja
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

Association between dietary intake of vitamin A, C, and E as antioxidants and cognitive function in the elderly at a nursing home Tani, Jowy; Widjaja, Ivan R.; Tedja, Irwin; Pratomo, Irandi P.; Siagian, Ira; Fahri, Indra; Amri, Zarni; Bardosono, Saptawati
Medical Journal of Indonesia Vol 16, No 4 (2007): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (138.577 KB) | DOI: 10.13181/mji.v16i4.289

Abstract

As oxidative stress is considered one of the major mechanisms underlying degenerative changes, antioxidants from dietary sources, such as vitamin A, C, and E, may have protective effects against oxidative stress and thus be able to prevent or delay cognitive impairment in the elderly. This cross sectional study was designed to determine the association between dietary intake of vitamin A, C, and E and the presence of cognitive impairment in the elderly, along with other factors. Subjects included 36 residents from a nursing home in Jakarta, Indonesia. The data obtained including daily nutrition intake values one week prior to sampling converted from semi- quantitative food frequency questionnaire (SFFQ) results, Mini Mental State Examination (MMSE) scores, and anthropometrical measurement results. This study showed that while sex, age, education, nutritional status, and macronutrients intake were not significantly associated with presence of cognitive impairment, significant positive correlation existed between education and MMSE score (p=0.036, r=0.351). Higher vitamin A and vitamin C intake were shown to be significantly associated with lower incidence of cognitive impairment (p=0.022 and p=0.045, respectively). Moreover, vitamin C was shown to have significant positive correlation with MMSE score (p=0.031, r=0.359). However, the association between vitamin E and the presence of impairment was not significant (p=0.129). Higher intake of vitamin A and C may delay or prevent cognitive impairment in the elderly. Higher intake of vitamin C may contribute to better cognitive functioning. The findings may be explained by the two antioxidant vitamins’ protective effects against neurode generative processes cause by oxidative stress. (Med J Indones 2007; 16:261-6)Keywords: antioxidant, vitamin A, vitamin C, vitamin E, cognitive impairment, the elderly
Effects of an additional small group discussion to cognitive achievement and retention in basic principles of bioethics teaching methods Afandi, Dedi; Budiningsih, Yuli; Safitry, Oktavinda; Purwadianto, Agus; Novitasari, Dwi; Widjaja, Ivan R.
Medical Journal of Indonesia Vol 18, No 1 (2009): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.893 KB) | DOI: 10.13181/mji.v18i1.340

Abstract

Aim The place of ethics in undergraduate medical curricula is essential but the methods of teaching medical ethics did not show substantial changes. “Basic principles of bioethics” is the best knowledge to develop student’s reasoning analysis in medical ethics In this study, we investigate the effects of an additional small group discussion in basic principles of bioethics conventional lecture methods to cognitive achievement and retention. This study was a randomized controlled trial with parallel design. Cognitive scores of the basic principles of bioethics as a parameter was measured using basic principles of bioethics (Kaidah Dasar Bioetika, KDB) test. Both groups were attending conventional lectures, then the intervention group got an additional small group discussion.Result Conventional lectures with or without small group discussion significantly increased cognitive achievement of basic principles of bioethics (P= 0.001 and P= 0.000, respectively), and there were significant differences in cognitive achievement and retention between the 2 groups (P= 0.000 and P= 0.000, respectively).Conclusion Additional small group discussion method improved cognitive achievement and retention of basic principles of bioethics. (Med J Indones 2009; 18: 48-52)Keywords: lecture, specification checklist, multiple choice questions
Metabolic syndrome and Framingham risk score in obese young adults Widjaja, Felix F.; Widjaja, Ivan R.; Astria, Yuni; Suwita, Christopher S.; Waspadji, Sarwono
Medical Journal of Indonesia Vol 22, No 2 (2013): May
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.682 KB) | DOI: 10.13181/mji.v22i2.536

Abstract

Background: The increase number of the metabolic syndrome (MetS) among young adults was mostly caused by obesity. MetS increases the risk of coronary heart disease (CHD) which can be estimated by Framingham risk score (FRS). The study was aimed to know the prevalence of MetS and FRS in obese young adults and to associate them with the components of MetS. Methods: A total of 70 male and female students aged 18 to 25 years with BMI ≥ 25 kg/m2 in Faculty of Medicine Universitas Indonesia were selected consecutively. The blood samples used to test fasting blood glucose, total cholesterol, high-density lipoprotein, and triglyceride were examined in Department of Clinical Pathology, Cipto Mangunkusumo Hospital after fasting for 14 to 16 hours. International Diabetes Federation (IDF) definition was used to diagnose MetS. Univariate and bivariate analysis were done. Results: The prevalence of MetS based on IDF definition was 18.6% among obese young adults. The most associated MetS components was hypertriglyceridemia (OR 12.13; 95% CI 2.92-50.46; p = 0.001), followed with high blood pressure (OR 9.33; 95% CI 2.26-38.56; p = 0.001), low-HDL (OR 8.33; 95% CI 2.17-32.05; p = 0.003), and impaired fasting glucose (p = 0.03). Four subjects had FRS ≥ 1% and 66 subjects had risk < 1%. Increased FRS was not associated with MetS (p = 0.154). There was no component of MetS associated with increased FRS. Conclusion: Prevalence of MetS in obese young adults was similar with obese children and adolescents. Although no association of MetS and FRS was found, they are significant predictors for CHD which should not be used separately. (Med J Indones. 2013;22:100-6)Keywords: Abdominal obesity, Framingham risk score, metabolic syndrome, young adults