Article Per Year (5 Year)
p-Index From 2021 - 2026
1.431
P-Index
This Author published in this journals
All Journal JURNAL GIZI INDONESIA Martabe : Jurnal Pengabdian Kepada Masyarakat Pontianak Nutrition Journal (PNJ) Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan Indonesia Berdaya Mattawang: Jurnal Pengabdian Masyarakat Majalah Ilmiah UPI YPTK Nursing Care and Health Technology Journal (NCHAT)
Sofiyetti, Sofiyetti
Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Jambi, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : JURNAL GIZI INDONESIA

 1 
Pengaruh suplementasi seng dan vitamin B6 terhadap kadar hemoglobin, hematokrit dan indeks eritrosit pasien malaria vivax yang anemia Sofiyetti, Sofiyetti; Dharmana, Edi; Rahfiludin, M. Zen; W, Nyoman Suci; Afifah, Diana Nur
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 1 (2016)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (509.713 KB) | DOI: 10.14710/jgi.5.1.20-25

Abstract

Background: Zinc supplementation decrease the risk of malaria parasitaemia, increasing ferritin serum level and hemoglobin in patients with malaria. Zinc influence the activity of aminolevulinic acid dehydratase (ALAD) an enzymes that catalizes heme synthesize. Vitamin B6 in pyridoxal 5-phosphate (PLP) from has a role in alpha-aminolevulinic acid (ALA) formation, which is the precursor of heme in hemoglobin. PLP also inhibit the growth of the malaria parasite.Objective: The objective was to analyze the effect of zinc and vitamin B6 supplementation on hemoglobin level, hematocrit and erythrocyte indexs (MCV, MCH and MCHC) of anemic Plasmodium vivax malaria patients.Methods: Double Blind Randomised Controlled Trial with pre and post test design. 30 subjects were divided into two groups: the suplementation group were given zinc 1x10 mg/day with vitamin B6 1x5 mg/day and the control group were given a placebo for 30 days. Data analysis by paired t-test, independent t-test and Mann Whitney.Results: There was an increase in Hb levels in the suplementation group (p=0.0001), the control group (p=0.001) and there was a significant difference on the increase between the two groups (p=0.020). Hematocrit significant increase only in the suplementation group (p=0.0001). There were no differences on erythrocyte index parameter in both groups.Conclusion: Zinc and vitamin B6 supplementation of for 30 days increase the hemoglobin level, hematocrit and there were no effect on erythrocyte indexs of anemic Plasmodium vivax malaria patients.
Co-Authors Abda Abda Almuhaimin, Almuhaimin Diana Nur Afifah, Diana Nur Dona Muin Edi Dharmana Elen Yusmi Elita Hisran, Hisran M. Rifqi Efendi Mesa Sukmadani Rusdi Mohammad Zen Rahfiludin Muhaimin, Al Mustofa, Kartika Nyoman Suci W, Nyoman Suci Sabarudin Sabarudin Usmaningrum, Desif Upix