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All Journal Jurnal Abdi Masyarakat Kita Jurnal Ilmiah Kesehatan Delima (JIKD)
Siti Lailatu Zahroh
STIKes Salsabila Serang
Public Health

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PENGABDIAN MASYARAKAT TENTANG DAGUSIBU (DAPATKAN, GUNAKAN, SIMPAN DAN BUANG) OBAT DENGAN BENAR DI SMK IKPI LABUAN PANDEGLANG Yusransyah Yusransyah; Sofi Nurmay Stiani; Siti Lailatu Zahroh
Jurnal Abdi Masyarakat Kita Vol 1 No 1 (2021): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1054.104 KB) | DOI: 10.33759/asta.v1i1.95

Abstract

Efforts to improve health for the community are very important. This is reinforced by the launching of DAGUSIBU (Get, Use, Store and Dispose of Medicines properly) so that the community is able to understand and be able to implement it in an effort to increase the degree of understanding in terms of medicine, especially how to get, use, store, dispose of drugs properly and create a drug-aware family through the DAGUSIBU program in the SMK IKPI School of Labuan Pandeglang. Material that is socialized is the explanation of the general definition of drugs, drug classification consisting of over-the-counter drugs, limited free drugs, hard drugs, and mandatory drug pharmacies. Then the explanation of the drug preparations and how to use them, special attention is needed so that they are not wrong in using them and the proper and correct storage and disposal procedures for the drugs. It is hoped that through this activity, the ultimate goal to be achieved will be realized, and the community will become a concern in consuming and managing medicines, especially those in the family environment.
Optimasi Formula Tablet Black Garlic Menggunakan Kombinasi Laktosa dan Avicel Ph 102 dengan Metode Simplex Lattice Design Siti Lailatu Zahroh; Sofi Nurmay Stiani; Eva Kholifah
Jurnal Ilmiah Kesehatan Delima Vol. 5 No. 2 (2023): Jurnal Ilmiah Kesehatan Delima
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Sekolah Tinggi Ilmu Kesehatan Salsabila Serang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60010/jikd.v5i2.95

Abstract

The study aims to find out whether the combination of lactose and avicel pH 102 can be formulated into black garlic extract tablet in accordance with the Indonesian Pharmacopoeia, the influence of combination, and determine the optimum formulation of the two ingredients using the SLD method. Methods used in this research Black Garlic extract is made by maceration method with 96% ethanol solvent with an extract weight of each tablet of 400 mg. Black garlic extract tablets are made in three formulations with a ratio of lactose-avicel PH-102, namely FI (100%:0%), FII (50%:50%), and FIII (0%:100%). Result shows that the optimum formula obtained was 80% lactose and 20% avicel PH 102 with a total predicted value of 0.645. The greater the concentration of avicel PH 102 as a crushing material, the faster the time rate of destruction, the hardness decreases, and the fragility value rises. The higher the concentration of the filler, the longer the crushing time it will take. The results of the statistical analysis of the three formulas tested showed the absence of significant differences between flow time, hardness, and brittleness, while crushed time tests showed the presence of significant differences (p?0.05). Tujuan penelitian ini adalah kombinasi antara laktosa dan avicel pH 102 dapat diformulasikan menjadi sediaan tablet sesuai dengan Farmakope Indonesia, pengaruh tehadap kombinasi dan penentuan formulasi yang optimum dari kedua bahan tersebut dapat dilakukan dengan metode SLD. Metode dalam penelitian ini adalah Ekstrak Black Garlic dibuat dengan metode maserasi dengan pelarut etanol 96% dengan bobot ekstrak setiap tablet 400 mg. Tablet ekstrak black garlic dibuat tiga formulasi dengan perbandingan laktosa-avicel PH-102 yaitu FI (100%:0%), FII (50%:50%) dan FIII (0%:100%). Hasil penelitian menunjukkan bahwa formula optimum yang diperoleh adalah 80% laktosa dan 20% avicel PH 102 dengan total nilai prediksi 0.645. Semakin besar konsentrasi avicel PH 102 sebagai bahan penghancur, maka tingkat waktu hancur semakin cepat, kekerasan semakin turun, nilai kerapuhan semakin naik. Semakin tinggi konsentrasi pengisi, maka semakin lama waktu hancur yang dibutuhkan. Hasil analisis statistik dari ketiga formula yang diuji menunjukkan tidak adanya perbedaan yang signifikan antara waktu alir, kekerasan dan kerapuhan, sedangkan untuk uji waktu hancur menunjukkan adanya perbedaan yang signifikan (p?0.05).
Co-Authors Eva Kholifah Stiani, Sofi Nurmay Yusransyah, Yusransyah