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All Journal Majalah Kedokteran Bandung Jurnal Anestesi Perioperatif Althea Medical Journal Jurnal Neuroanestesi Indonesia The Journal of Society Medicine (JSOCMED)
Ardi Zulfariansyah
Departemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Padjadjaran/Rumah Sakit Dr. Hasan Sadikin Bandung
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Perbandingan Nilai Diskriminasi Modified NUTRIC Score dan Skor APACHE II Terhadap Mortalitas 28 Hari Pada Pasien Sepsis Yang Dirawat Di ICU Mulyawan, Dadang; Pradian, Erwin; Zulfariansyah, Ardi
Jurnal Anestesi Perioperatif Vol 14, No 1 (2026)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v14n1.4027

Abstract

Introduction: Sepsis with malnutrition increases complications and mortality in ICU patients. The modified Nutrition Risk in Critically Ill (mNUTRIC) score assesses nutritional risk and predicts mortality, whereas APACHE II does not account for nutritional status. This study compared mNUTRIC and APACHE II for predicting 28–day mortality in ICU patients with sepsis. Methods: This prospective observational study was conducted from February to April 2024. Sepsis patients admitted during the study period were included. Discriminatory performance for predicting 28–day mortality was evaluated using the area under the receiver operating characteristic curve (AUROC). Comparison between scoring systems was performed using DeLong’s non–parametric test.Results: A total of 39 ICU patients were included. The mean mNUTRIC score was 4.44±2.23, and the mean APACHE II score was 17.59±5.28. The AUROC value was 0.825 for the mNUTRIC score and 0.789 for the APACHE II score. DeLong’s test showed that the mNUTRIC score had significantly better discrimination for predicting 28–day mortality than the APACHE II score (p=0.011).Discussion: mNUTRIC integrates nutritional and chronic health factors, capturing patients’ physiological reserve more comprehensively than APACHE II. Early identification of high–risk patients may guide targeted interventions and ICU resource allocation.Conclusion: The mNUTRIC score demonstrated superior discriminatory ability compared to the APACHE II score in predicting mortality among sepsis patients in the ICU. Incorporating nutritional risk assessment may improve mortality prediction and clinical decision–making in critically ill sepsis patients.
Mortality Outcomes Associated with Blood Group O Versus Non-O in Patients Undergoing Coronary Artery Bypass Grafting Oktaliansah, Ezra; Maskoen, Tinni T.; Oey, Bernadeth; Suwarman, Suwarman; Pradian, Erwin; Zulfariansyah, Ardi
Jurnal Anestesi Perioperatif Vol 14, No 1 (2026)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v14n1.4640

Abstract

Background: Coronary artery bypass grafting (CABG) carries an operative mortality of 1–7%. Von Willebrand factor (vWF) levels are approximately 30% lower in individuals with blood group O compared to non–O groups, potentially influencing post–CABG mortality. This study aimed to compare mortality between blood group O and non–O in adult patients after on–pump CABG in the ICU.Methods: A retrospective cohort study was conducted using secondary data from medical records of adult patients (>18 years) who underwent elective on–pump CABG in the ICU at Dr. Hasan Sadikin General Hospital, Bandung. A sample of 64 patients was required, with a 28–day follow–up post–CABG. Data were analyzed using unpaired t–tests, Mann–Whitney tests, Chi–square, and Fisher’s exact tests, with significance set at p<0.05, using SPSS version 26.0.Results: A total of 129 patients were included, comprising 64 patients with blood group O and 65 with non–O blood groups. Mortality in blood group O patients was 10.9% (7/64), compared with 29.2% (19/65) in non–O patients, a significant difference (p=0.010). Non–O blood group patients had nearly three times higher risk of mortality compared to those with blood group O.Discussion: The observed mortality differences are related to variations in vWF and factor VIII levels among blood groups. Lower vWF levels in blood group O may provide a protective effect against macro–thrombosis in coronary grafts, whereas higher factor VIII levels in non–O groups increase the risk of microvascular thrombosis and secondary myocardial ischemia after on–pump CABG.Conclusion: Adult patients undergoing on–pump CABG with non–O blood groups experience significantly higher mortality compared to those with blood group O. Blood group may be associated with postoperative mortality. However, its role as an independent prognostic factor requires further investigation.
Co-Authors A. Muthalib Nawawi Adani, Shadrina Dinan Ade Arya Nugraha Arief Kurniawan Arifin, Ilman Hakim Budiana Rismawan Dadang Mulyawan Erwin Pradian Ezra Oktaliansah Iwan Fuadi Oey, Bernadeth Putra, Angga Permana Putri Teesa Radhiyanti Santoso Radian Ahmad Halimi Ruli Herman Sitanggang Salukanan, Ronald Tikuali Saputra, Maulidar Sitorus, Richard Pahala Suwarman Suwarman Suwarman Suwarman, Suwarman Tatang Bisri Tinni T. Maskoen