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All Journal Medical Journal of Indonesia Journal of Community Empowerment for Health eJournal Kedokteran Indonesia IJRETINA - International Journal of Retina Ophthalmologica Indonesiana
Andayani, Gitalisa
Department Of Ophthalmology, Faculty Of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; JEC Eye Hospital, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Ophthalmologica Indonesiana

 1   2 
The Challenges in Managing Proliferative Diabetic Retinopathy with Neovascular Glaucoma Putri A Idham; Elvioza Elvioza; Andi Arus Victor; Gitalisa Andayani; Ari Djatikusumo; Anggun Ramayudatha
Majalah Oftalmologi Indonesia Vol 41 No 1 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v41i1.3

Abstract

Background: The aim of this study is to emphasize the importance of close monitoring of the disease progression, minimize late complication, and knowing the important parameters of succesful treatment.Methods: A 52 years old woman with proliferative diabetic retinopathy was referred to Vitreoretina division. Patient came with chief complaint blurry vision of the left eye. Patien was diagnosed with diabetes melitus type 2 since 10 months ago. At ophthalmological examination, there was iris neovascularization on the left eye. Due to this finding, patient was given treatment for the proliferative diabetic retinopathy and neovascular glaucoma.Results: The patient undewent intravitreal injection of bevacizumab and Kehki Meta implant surgery after panretinal photocoagulation laser. Neovascularization of the iris was regressed and the intraocular pressure was controlled.Conclusion: This patient underwent laser panretinal photocoagulation, bevacizumab injection and Keiki Mehta implant surgery. The result was good. The neovascularization was regressed. Closed monitoring should be continued to evaluate the progression of the disease and control the intraocular pressure to prevent further visual loss. Keywords: Proliferative diabetic retinopathy, neovascular glaucoma, diabetic macular edema
Medium Duration Threshold Patterned Laser Photo­ coagulation for Panretinal Photocoagulation Habsyiyah Habsyiyah; Elvioza Elvioza; Andi Arus Victor; Ari Djatikusumo; Gitalisa Andayani; Anggun Rama Yudantha
Majalah Oftalmologi Indonesia Vol 41 No 1 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v41i1.8

Abstract

Background: Laser photocoagulation is a crucial therapy for numerous retinal diseases. Laser can be delivered with different machines and modalities (slit lamp, endolaser, indirect laser) at different wavelengths (532 to 812 nm) with varying parameters (power, spot size, duration, number of spots). New developments using semi automatic pattern delivery of retinal laser burns which use smaller amounts of energy and shorter duration have been reported. This literature review is conducted to review various published article that reported efficacy, safety, and duration of medium duration threshold patterned (MDTP) laser photocoagulation.Methods: This literature review was conducted from the Pubmed (NLM) database and Ophsource using the keyword panretinal photocoagulation, and Pascal or medium threshold or short exposure. The inculsion criteria of this review were all of studies which reported the use of medium duration threshold patterned which was applied as panretinal photocoagulation (PRP).Results: Parameter used in MDTP laser were as follow, spot size was between 200 to 400 μm, duration was 20-30 ms, and average laser power was more than 200 to 630 mV. Compare to standard laser treatment, power used in MDTP laser were higher.Conclusion: Medium duration threshold patterned laser photo-coagulation is as effective as conventional laser. MDTP laser can preserve the retinal sensitivity/visual field, also offers less pain and discomfort and safe to perform full scatter PRP in single sitting Keywords: medium duration threshold patterned laser; panretinal photocoagulation
Various Tamponade in Surgery for Retinal Detachment Associated with Proliferative Vitreoretinopathy Faraby Martha; Andi A Victor; Elvioza Elvioza; Ari Djatikusumo; Gitalisa A Andayani; Anggun R Yudantha
Majalah Oftalmologi Indonesia Vol 41 No 2 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v41i2.24

Abstract

Background: To review the literature and report relative efficacy and safety of various tamponade agents used with surgery for rhegmatogenous retinal detachment (RRD) complicated by proliferative vitreoretinopathy (PVR) regarding functional success rate, anatomical success rate, and adverse effects. Methods: We searched articles from PubMed and Clinical Key database starting from the year of 1990 to November 2014. Information needed from all articles were extracted into data extraction sheet. We reviewed the efficacy of both tamponade agents regarding the postoperative visual acuity, macular attachment, and adverse effect. Results: Eight articles were included after fulfilling inclusion and exclusion criteria. Our analysis showed all studies shows an increasing visual acuity and percentage of macular attachment postoperatively of all type tamponade agents. Functional and anatomical success rate of Sulfur hexafluoride gas (SF6) was high in study with PVR stage B or less (94-98%). In patient with complex or recurrent RD associated with PVR, silicone oil had a better functional success (51% vs 32.5%) and better anatomical success (80% vs 60%) than SF6 gas. The anatomical success rate also higher in C3F8 than in SF6 group (73.9% vs 57.5% respectively). Functional and anatomical success rate of HSO as tamponade was high in patients with a severe PVR located mainly in the inferior quadrants (92.3%).Conclusion: As tamponade agents, C3F8 and silicone oil appear to have more visual and anatomic advantages over SF6 in participants with complex or recurrent RD associated with PVR. Silicone oil was better than C3F8 gas to obtain final visual and anatomic successs in patient with recurrent RD associated with higher grade PVR. Heavy silicone oil would be useful in particular cases complicated by recurrent inferior RD with PVR. Retinal redetachment, glaucoma, cataract, hypotony and keratopathy were reported in both gases and silicone group. Keywords: Tamponade in retinal detachment surgery, SF6, C3F8, silicon oil, and heavy silicone oil
Comparison between Intravitreal Bevacizumab and Triamcinolone Acetonide in Management of Diabetic Macular Edema Simon A Siregar; Elvioza Elvioza; Andi A Victor; Ari Djatikusumo; Gitalisa A Andayani; Anggun R Yudantha
Majalah Oftalmologi Indonesia Vol 42 No 1 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i1.61

Abstract

Background: To critically evaluate the efficacy and safety profile of intravitreal bevacizumab (IVB)compared to intravitreal triamcinolone acetonide (IVTA) in patients with diabetic macular edema(DME).Methods: We searched publication related to diabetic macular edema managed by bevacizumab andtriamcinolone acteonide through systematic search of database in a period of January 2002 untilOctober 2013. Information needed from all articles were extracted into a data extraction sheet. Wereviewed the efficacy of both treatment in decreasing central macular thickness (CMT), improvementof visual acuity and the adverse effects following the injection.Results: Twelve articles were included after fulfilling inclusion and exclusion cirteria. Our analysisshowed single IVTA injection were more effective in decreasing CMT and improving visual acuity at1 week to 3 months. There were no significant improvement of CMT in multiple injection of IVTAcompared to multiple injection of IVB.Conclusion: A single intravitreal injection of IVTA appears to offer certain short-term advantagesover IVB for the management of patients with diabetic macular edema, particularly with regard toCMT. Keywords: intravitreal, triamcinolone acetonide, bevacizumab, diabetic macular edema
Inter-observer Agreement in Fundus Photography for Diabetic Retinopathy Screening in Primary Health Care Alia Arianti; Gitalisa A Andayani
Majalah Oftalmologi Indonesia Vol 42 No 2 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i2.84

Abstract

Background: To assess the agreement between a group of trained non-physician ophthalmic careproviders as primary grader, and vitreoretina specialist as secondary grader, in the interpretation ofsingle-field 45o, non-mydriatic digital fundus image for diabetic retinopathy (DR) screening in primaryhealth care.Methods: This is an analytic, retrospective study. A total of 117 fundus images of diabetic patientswere graded by primary grader, followed by secondary grader using the modified National ScreeningCommittee (NSC) as a guideline. Kappa statistics and Intraclass Correlation (ICC) were used for thereliability assessment of photograph quality, DR presence and classification, presence of maculopathyand photocoagulation, severity level, and presence of vision-threatening diabetic retinopathy (VTDR).Diagnostic values of fundus image interpretation by primary grader in detecting DR using secondarygrader as the reference standard were also assessed.Results: Agreement for DR classification and its severity level was good (ICC 0.654; 0.642). Fairagreement was found for presence of maculopathy and VTDR (κ 0.368; ICC 0.595). Slight agreementwas found for photograph quality (κ 0.170). The percentage agreement in identifying DR was 29.9%.Sensitivity and specificity of fundus image interpretation by primary grader in DR and VTDR detectionwere 52.24% and 71.43%, 54.55% and 95.12%, consecutively.Conclusion: The reliability of primary grader for interpreting single-field fundus photography in DRscreening has not reached the ideal result in this study (κ more than 0.6 in all variables). Acomprehensive training with continuing education is essential for non-physician personnel, to ensurethe reliability of DR screening program using single-field fundus photography.Keywords: diabetic retinopathy screening, interobserver agreement, kappa value, intraclass correlation.
Current Therapy of Diabetic Macular Edema Bevacizumab, Triamcinolone Acetonide, and Laser Photocoagulation Gladys Kusumowidagdo; Randy Sarayar; Kartika Rahayu; Gitalisa Andayani
Majalah Oftalmologi Indonesia Vol 45 No 1 (2019): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v45i1.172

Abstract

Background: Diabetic macular edema (DME) is the main cause of visual impairment in diabetic retinopathy (DR). Current gold standard therapy of DME is macular laser photocoagulation (MPC). Growing evidences have shown benefits of intravitreal anti-VEGF agents (i.e bevacizumab) and intravitreal corticosteroids (i.e triamcinolone acetonide). Aim: To compare the visual acuity (VA) improvement of patients with DME, treated with intravitreal bevacizumab (IVB), a combination of IVB and intravitreal triamcinolone (IVB/IVT), and MPC. Method: A comprehensive PubMed® and Cochrane® databases search was conducted on May 4th, 2017 using appropriate keywords (diabetic macular edema, bevacizumab, triamcinolone, and laser photocoagulation using their MeSH terms). Studies were filtered using inclusion criterions (clinical trials, RCT, meta-analysis, systematic review, English, humans, and publication within 10 years) Results: Three studies (2 systematic reviews and 1 RCT) were found suitable. From these results, all studies showed favoring effects of IVB when compared to IVB/IVT combination and MPC in short term period (up to 6 months). However, there was no significant improvement of VA beyond this period in all groups. Conclusion: IVB appears to be superior to IVB/IVT and MPC in improving VA during 6 months follow- up period. Future systematic reviews and meta-analysis are required on the effect of IVB and MPC combination in cases of DME.
Pneumatic Retinopexy in Rhegmatogenous Retinal Detachment : Case Series Fauzan Teuku Banta; Ari Djatikusumo; Elvioza Elvioza; Gitalisa Andayani; Anggun Rama Yudhanta; Mario Marbungaran Hutapea; Andi Arus Victor
Majalah Oftalmologi Indonesia Vol 45 No 2 (2019): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v45i2.184

Abstract

In the case of rhegmatogenous retinal detachment (RRD), pneumatic retinopexy is an alternative choice besides scleral buckling and pars plana vitrectomy. This case series describes two cases of RRD with superotemporal tear treated succesfully with pneumatic retinopexy. The expandable gas used in this study was 0.4 cc perfluoropropane (C3F8) gas, patient’s head is immediately positioned face down (prone), then slowly turned into an upright position in accordance with the tear for 1-3 days. Laser retinopexy using an argon laser is performed after the retina is properly reattached. Ten months after pneumatic retinopexy, the VA of RE in case I remained at 6/18 with reattached retina. At four weeks, VA of RE in case II was at 3/60 with reattached retina. VA of both cases was relatively satisfactory with retinal reattachment in a single procedure. The anatomical and functional success of pneumatic retinopexy is related to macular status before surgery, retinal detachment area, phakic status, or the presence of PVR and high myopia.
Vitrektomi dengan Anestesi Lokal pada Ablasio Retina Rhegmatogen di Rumah Sakit Cipto Mangunkusumo Andhika Guna Dharma; Ari Djatikusumo; Elvioza Elvioza; Gitalisa Andayani Adriono; Anggun Rama Yudantha; Mario Marbungaran Hutapea; Andi Arus Victor
Majalah Oftalmologi Indonesia Vol 46 No 2 (2020): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v46i2.100090

Abstract

Latar Belakang: Vitrektomi pada ablasio retina dapat dilakukan dengan anestesi umum maupun anestesi lokal. Anestesi lokal kerap dipilih atas keunggulannya dalam efisiensi waktu dan biaya. Tujuan: Memaparkan tingkat keberhasilan anatomi dan fungsional vitrektomi dengan anestesi lokal pada ablasio retina rhegmatogen di Divisi Vitreoretina RSCM-FKUI. Metode: Penelusuran retrospektif pada 42 pasien ablasio retina rhegmatogen yang dilakukan vitrektomi dengan anestesi lokal di RSCM-FKUI pada Januari 2017 – Juni 2017.Hasil: Terjadi peningkatan tajam penglihatan pada enam bulan pasca vitrektomi dengan anestesi lokal yaitu visus ?1/60 dari 55% menjadi 77%. Kondisi retina menempel pasca tindakan operasi vitrektomi dengan anestesi lokal sebanyak 93%. Kesimpulan: Tingkat keberhasilan fungsional sebesar 77% dan keberhasilan anatomis 93%.
Treatment of Vitreous Hemorrhage due to Proliferative Diabetic Retinopathy in Cipto Mangunkusumo Hospital During Pandemic Era (March 2020 - March 2022): Oral Presentation - Observational Study - Resident RAHAYU, TSANIA RACHMAH; Andayani, Gitalisa
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/11wn7q74

Abstract

Introduction & ObjectivesProliferative diabetic retinopathy (PDR) is the most common etiology for vitreous hemorrhage (VH)and can be sight-threatening. Current treatment modalities for VH in PDR included anti-VEGFinjection, panretinal photocoagulation (PRP) laser, and vitrectomy. We conducted study to evaluatetreatment modalities and outcomes of VH in PDR during the pandemic era. MethodsA retrospective study of VH in PDR was conducted at Cipto Mangunkusumo Hospital, Indonesia,from March 2020 to March 2022. Primary treatment was the therapy planned at the initial visit,while secondary treatment was subsequent treatment after follow-ups. Good anatomical outcomewas defined as vitreous clearing at last follow-up, while functional outcome was visual acuity (VA)improvement in LogMAR. ResultsThis study included 83 patients (97 eyes), which is smaller than the previous study in our centerbefore the pandemic. Mean age was 54,28±8,57 years, with almost equal males and females. InitialVA was LogMAR 2,48 (0,15 – 2,80). The most frequent treatment for VH in PDR was vitrectomy(53,5%), followed by anti-VEGF injection, PRP laser, and observation. Glaucoma after vitrectomy wasthe most common complication (5,2%). Vitreous clearing was achieved in 85,5% of cases, which wassignificantly associated with vitrectomy surgery (p=0,013) and initial treatment time (p=0,023). TheVA improvement was LogMAR -0,48(-2,48–2,40) which was related to initial VA (p<0.05), yet therewas no significant association with treatment modality. ConclusionVitrectomy is essential to achieve vitreous clearing in VH caused by PDR. Initial visual acuity, notthe type of treatment modality, is a significant factor in vision improvement.
From the Eye to the Heart: Association between Age-Related Macular Degeneration and Cardiovascular Disease (a Systematic Review): Oral Presentation - Observational Study - General practitioner Sausan; Presialia, Athira; Khalifah, Rasyad; Adriono, Gitalisa Andayani
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ax8d9687

Abstract

Introduction & ObjectivesAge-related macular degeneration (AMD) is the third leading cause of global blindness, whilecardiovascular disease (CVD) is recognized as a major cause of morbidity and mortality. Both arecomplex diseases associated with aging. It has recently been argued that there is an associationbetween AMD and CVD. This study examined whether AMD increased the risk of CVD and/ or CVDmortality. MethodsA systematic review was conducted through three databases (Pubmed, Scopus, and Embase) forrelevant studies published between 2016-2023. We selected studies which focused on subjects withAMD, regardless of stages, and their risks for developing CVD and/or CVD mortality. ResultsTwo cohort studies and one case-control study are included, involving 93.388 patients aged >40years old. One cohort study found that subjects with choroidal neovascularization were associatedwith an increased rate of cardiovascular mortality (HR 3.16 95% CI 1.62-6.15). Another study alsofound that AMD was associated with a 1.58 fold increased risk of heart failure (adjusted OR, 1.56;95% CI, 1.16–1.87; P<0.001) after adjustment for confounders. Moreover, aside from the variableson which this systematic review focused on, the cohort studies also found AMD correlation withother diseases and causes of mortality. ConclusionIndividuals with AMD have higher risk for developing CVD. Thus, screening for AMD may bebeneficial in preventing CVD.
Co-Authors Agung Nugroho Agustiawan, Referano Ali, Reyno Satria Alia Arianti Andhika Guna Dharma Andi A Victor Andi A Victor Andi Arus Victor Andi Arus Victor Andi Arus Victor Andi Arus Victor Andi Arus Victor Andi Arus Victor Andi Arus Victor Andi Marsa Nadhira Anggun R Yudantha Anggun R Yudantha Anggun Rama Yudantha Anggun Rama Yudantha Anggun Rama Yudantha Anggun Rama Yudantha Anggun Rama Yudantha Anggun Rama Yudantha Anggun Rama Yudantha Anggun Rama Yudhanta Anggun Ramayudatha Annisa Windyani Ari Andayani Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Ari Djatikusumo Arief S. Kartasasmita Bani, Anna Puspitasari Barus, Dany Petra Pranata Daniel, Hisar Dearaini Dharma, Andhika Guna Dicky Budiman Simanjuntak Djatikusumo, Ari Eko Hadi Waluyojati Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza Elvioza, Elvioza Faraby Martha Faresa Hilda Fauzan Teuku Banta Firmansyah, M Gladys Kusumowidagdo Habsyiyah Habsyiyah Harley, Ohisa Hutapea, Mario Marbungaran Ichsan, Andi M Irawati, Yunia Isfyanto, Isfyanto Iskandar, Erwin Kartika Rahayu Khalifah, Rasyad King Hans Kurnia Laksmita, Yulinda Arty Leonedine, Tengku Viona Zohra Made Susiyanti Mahfudz, Sausan Rasyid Mario Marbungaran Hutapea Mario Marbungaran Hutapea Mario Marbungaran Hutapea Mario Marbungaran Hutapea Mario Marbungaran Hutapea Mario Marbungaran Hutapea Mario Marbungaran Hutapea Martin Hertanto Masniah Masniah Nadia Artha Dewi Noviana Kurniasari Vivin Pambudy, Indra Maharddhika Pangestika, Rishka Presialia, Athira Puspitasari, Sitha Anisa Putri A Idham RAHAYU, TSANIA RACHMAH Randy Sarayar Sausan Sembiring, Sindy Boru Simon A Siregar Sindy Boru Sembiring Sjahreza, Emil Suryoadji, Kemal Akbar Susantono, Diannisa Paramitha Susilo, Teguh Tri Rahayu Triwijayanti Triwijayanti Triyoga, Ichsan Fauzi Victor, Andi Arus Wicitra, Anindita Widyawati, Syska Yeni Dwi Lestari Yudanta, Anggun Rama Yudantha, Anggun Rama Yudhanta, Anggun Rama Yulia Aziza Yustiarini, Ima