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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Kesehatan Andalas Damianus Journal of Medicine Dental Journal (Majalah Kedokteran Gigi) Universa Medicina Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) Indonesian Journal of Medicine Majalah Kedokteran Andalas Journal Orthopaedi and Traumatology Surabaya (JOINTS) Indian Journal of Forensic Medicine & Toxicology Jurnal Widya Medika
Komang Agung
Departemen/SMF Orthopaedi Dan Traumatologi, Fakultas Kedokteran Universitas Airlangga/RSUD Dr. Soetomo
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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A Comparison of Osteoblast Cell Proliferation and Osteocalcin Expression in Cuttlefish Bone and Bovine Bone Xenograft Komang Agung Irianto; Ameria Pribadi; Ilham Abdullah Irsyam; Yudhistira Pradnyan Kloping; Oen Sindrawati
Molecular and Cellular Biomedical Sciences Vol 3, No 2 (2019)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5757.072 KB) | DOI: 10.21705/mcbs.v3i2.58

Abstract

Background: Cuttlefish bone Xenograft, calcium phosphate (CaP)-based biomaterial graft, offers an alternative and has been accepted for osteoconductive and probable osteo-inductive attributes. This study aims to compare the bone healing potential between the bovine-derived (BHA) and cuttlefish bone-derived (CHA).Materials and Methods: The study compared osteoblast cell proliferation of 27 New Zealand rabbits in 2.5 mm bone defect made in the femoral bone. The samples were divided into three groups, which were control, BHA and CHA group. The chemical and physical characteristics of BHA and CHA were determined for the content of hydroxyapatite by FourierTransform Infrared Spectroscopy (FTIR) and X-Ray Diffraction (XRD), then tested by Scanning Electron Microscopy (SEM) to evaluate the porosity. In the end of the second week, histopathologic and immunohistochemistry examinations were performed to evaluate the amount of osteoblast and osteocalcin expression.Results: The FTIR, XRD and SEM analysis showed both BHA and CHA samples were hydroxyapatite according to Joint Committee on Powder Diffraction Standards (JCPDS). The CHA was significantly higher (297.22±19.772) compared to BHA (258.22±30.926) and control (131.67±34.213). Osteocalcin expression in CHA (7.82±2.230) compared to BHA (6.09±3.724) and control (4.07±3.606), was not significant (p>0.05). Conclusion: CHA group has the highest osteoblast cell proliferation and osteocalcin expression, meaning has a good potential as future source of bone graft.Keywords: cuttlefish bone, bovine, bone graft, osteoblast cell
Slipped Capital Femoral Epiphysis (SCFE) Laskar Pradnyan Kloping; Sulis Bayusentono; Komang Agung Irianto
Majalah Kedokteran Andalas Vol 44, No 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i2.p134-146.2021

Abstract

Slipped Capital Femoral Epiphysis (SCFE) adalah kelainan pada regio hip dimana didapatkan pergeseran dari epifisis kaput femoris mulai dari area metafisis hingga fisis. Prevalensi SCFE berbeda-beda mengikuti kelompok etnis tertentu, kondisi geografis, lokasi, dan perubahan musim. SCFE sering dijumpai pada anak-anak Hispanik dan Afrika dengan jumlah mencapai 3,94 hingga 2,53 kali dibandingkan anak-anak Kaukasia. Rasio antara anak laki-laki dibandingkan perempuan sebesar 1,6:1, dimana rasio ini mewakili usia puncak pertumbuhan mereka, yaitu usia 10 hingga 16 tahun, dengan usia rata-rata 12 tahun pada anak perempuan dan 13,5 tahun pada anak laki-laki. Pada pasien usia dewasa muda, SCFE dikaitkan dengan gangguan metabolisme endokrin. Faktor lain seperti genetika dapat berperan dalam SCFE dimana adanya riwayat di keluarga menyebabkan variabilitas yang lebih besar. Proses penentuan diagnosis yang tertunda dapat menyebabkan perburukan dari kondisi awal pasien, hingga terjadinya gejala proses degenerasi awal yang berujung arthritis sendi pinggul. Tidak jarang, diagnostik yang terlambat berujung pada kecacatan premanen. Dibutuhkan pemeriksaan awal (screening) berskala besar untuk SCFE yang belum pernah dilakukan hingga sekarang, agar proses penetuan diagnosis dapat dibuat lebih cepat.
BLOUNT DISEASE EVALUATION OF THE OPERATIVE TREATMENT WITHIN 2006-2014 IN DR. SOETOMO GENERAL HOSPITAL SURABAYA Komang Agung Irianto Suryaningrat; I. G. Ng. Dodo M. Ranuh
Journal Orthopaedi and Traumatology Surabaya Vol. 6 No. 2 (2017): October 2017
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v6i2.2017.55-62

Abstract

Background: Blount disease is a growth disturbance of the medial side of the proximal physeal of the tibia, epiphyseal and metaphyseal. Clinically this disease marked by varus angulation and internal rotation of the tibia on the metaphyseal area below knee.Method: This paper evaluating 2 cases of blount disease treated surgically in Soetomo general hospital within 2006 – 2014. The evaluation based on MDA (meta-diaphyseal angle) pre and post operatively.Result: Showed significant and satisfactory to patients and parents who have carried out the operation. A reduction in the angle of MDA, in first patients the MDA angle before surgery was 18 degrees on the right 40 degrees on the left, after surgery MDA was 24 degrees on the right, 10 degrees on the left. The second patient MDA before surgery was 32 degrees on the right and 33 degrees on the left, after the surgery MDA was 12 degrees on the left side, for the right side hasn’t operated yet.Discussion and Conclusion: There is hope for correction on severe form of blount disease. Correction by performing a proximal tibia osteotomy on the affected bone.
CONGENITAL SCOLIOSIS: AN ARTICLE REVIEW Komang Agung Irianto; Hizbillah Yazid
Journal Orthopaedi and Traumatology Surabaya Vol. 8 No. 1 (2019): April 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v8i1.2019.47-58

Abstract

Background: Congenital Scoliosis (CS) defined as vertebral lateral deviation which forms during the intrauterine embryonic phase, carrying incidence between 0,5-1 per 1000 births. Mortality rate increases in untreated case, especially due to pulmonary problem (40%).Contents: CS can range from hemivertebrae (HV) which may be single or multiple, vertebral bar with or without HV, block vertebrae, wedge shaped or butterfly vertebrae. The risk factors for progression include: type of defect, site of defect, and the patient’s age. Plain radiographs remain standard diagnosis. MRI evaluation should be considered. The goal of managing CS is to obtain a balanced trunk and spine while maintaining as much normal spinal growth as possible and preventing neural deficit. Non-operative management is including observation, brace, and traction. The operative procedures are broadly divided into (a) those preventing further deformity: in situ fusion, convex hemiepiphysiodesis, and HV excision, (b) those that correct the present deformity: hemiepiphyseodesis & hemiarthrodesis, single & dual growing rods, HV excision, and reconstructive osteotomy.Conclusion: The treatment of CS remains one of the more challenging aspects of pediatric orthopaedic surgery. Operative treatment should be reserved for patients whom non-operative management didn’t meet the criteria or failed.
CLINICAL EVALUATION OF POST TOTAL HIP / KNEE REPLACEMENT IN HIP / KNEE SPINE SYNDROME Achmad Fachrizal; Komang Agung Irianto
Journal Orthopaedi and Traumatology Surabaya Vol. 6 No. 1 (2017): April 2017
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v6i1.2017.40-47

Abstract

Insiden osteoarthritis pada hip joint, osteoarthritis pada knee joint, dan degenerative lumbar spondylosis semakin meningkat seiring dengan bertambahnya populasi penduduk usia tua. Kasus Hip/Knee Spine syndrome sendiri cukup sering ditemukan. Namun literatur yang mengevaluasi kondisi klinis, khususnya keluhan low back pain pada pasien dengan hip/knee spine syndrome post total hip/knee replacement masih sangat terbatas Tujuan dari penelitian ini adalah untuk mengevaluasi efek dari total hip/knee replacement pada pasien dengan hip/knee spine syndrome, berkaitan dengan keluhan low back pain.Penelitian ini adalah observasional retrospektif. Penelitian ini menggunakan 5 orang pasien post total hip/knee replacement yang juga didapatkan keluhan low back pain. Pasien yang terpilih akan dievaluasi klinis dengan menggunakan kuesioner LBP VAS Score, Oswestry Disability Index, Hip Harris Score untuk pasien post total hip replacement, dan Oxford Knee Score untuk pasien post total knee replacement. Dilakukan pengamatan pre dan post operasi pada seluruh pasien. Data pasien didapatkan dari Rumah Sakit Orthopaedi dan Traumatologi Surabaya mulai bulan Juni-November 2015.Berdasarkan test paired samples, didapatkan hasil sig 0,001 (< 0,05) pada skor VAS dan sig 0,033 (<0,05) pada skor ODI. Maka dapat disimpulkan bahwa terdapat perbedaan yang signifikan antara skor VAS LBP dan skor ODI sebelum dan setelah terapi Hip/Knee Replacement pada pasien dengan Hip/Knee Spine Syndrome.
The Role Of Rose (Rapid Onsite Evaluation) On Spinal Lesion Surgery Decision . Sindrawati; Komang Agung; Carlos Binti; Anggita Dewi
JURNAL WIDYA MEDIKA Vol. 5 No. 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v5i1.2000

Abstract

Introduction: Exposure and instrumentation of the spine must be meticulous and thorough regardless the techniques and approach selected. Management of the whole surgery process should be decided based on the best available evidence whenever possible. ROSE (Rapid Onsite Evaluation) cytology wrap up the surgical decision. Case Description: Fifteen cases comprise of lytic lesions and/or single pathological fractures of the corpus vertebrae will be presented and discuss as to how the surgical techniques and approaches are assisted by ROSE. ROSE cytology was performed in the operating theater during the surgery. Samples were taken after exposure of the minimal lesion using (18–21) G trocar needle or under fluoroscopy guided. Direct smear, air dried fixation, and Diff Quik staining would take about 10 minutes. Pathologist evaluated the specimen and provided the result in about 20 minutes. The overall 30 minutes allowed surgeon to prepare the further steps. Results would be malignant or benign without pursuing further detail diagnostic. Benign results should be categorized as infection, suspicious of granulomatic tuberculosis, or normal host population cells. The cases outcome were 8 normal host population cells advanced for vertebroplasty to fill the porotic bone. Three spondylitis tuberculosis were debrided without unnecessary instrumentation, and four malignant processes were assured to have enough samples for immunohistochemistry evaluation afterward. All ROSE cytology was confirmed accordingly by the histopathology result afterward. Conclusion: ROSE is easy and offers accurate sampling from the lesion itself. It is quick, therefore during surgery surgeon could decide the best management for the patient.
Release of retromalleolar flexor retinaculum and combined flexor digitorum longus and flexor hallucis longus Z-plasty in checkrein deformity: a case report Irianto, Komang Agung; Leonarto, Enrico; Handoyo, Henry Ricardo
Universa Medicina Vol. 42 No. 3 (2023)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2023.v42.368-373

Abstract

BackgroundCheckrein deformity is a rare abnormality comprising flexor hallucis longus (FHL) tendon entrapment in the posterior foot due to post-traumatic or ischemic retraction of the FHLtendon following soft tissue trauma. The diagnosis is essentially clinical, but complemented by imaging to rule out unrecognized causes and evaluate the fracture healing process. This case report is the first Indonesian study to describe release of the flexor retinaculum and Z-plasty (lengthening) of flexor digitorum longus (FDL) and FHL tendons through a medial retromalleolar approach to repair the deformity. Case DescriptionWe present the case of a 51-year-old male who complained of clawing of his right first and second toes. The interest of this study lies in the fact that this patient had never experienced ankle or distal tibial fractures, only a trivial injury two years back when the patient kicked a stone at work and had a bruise on his right second toe with no fracture. Exploration of FHL tendons was performed at the level of the midfoot. The patient was planned for surgery with a medial retromalleolar ankle approach, which facilitates the release of the flexor retinaculum, in conjunction with a Z-tenotomy on the FHL and FDL tendons. ConclusionA correction was achieved, and two months post-surgery there were no recurrences of the deformity. However, this surgical procedure requires more cases to support an evaluation of its effectiveness. We suggest that exploration at the ankle and midfoot should be the primary surgical intervention in similar cases of checkrein deformity.
Co-Authors . Sindrawati Achmad Fachrizal Adhinanda Gema Adityawardhana, Taufan Ameria Pribadi Andro Pramana Witarto Anggita Dewi Brahmana, Febrian Carlos Binti David Nugraha Dionisius Bramta Putra Gestana R Wardana Handoyo, Henry Ricardo Hizbillah Yazid I. G. Ng. Dodo M. Ranuh Ilham Abdullah Irsyam Kimberly Clarissa Oetomo Laskar Pradnyan Kloping Leonarto, Enrico Martanto, Tri Wahyu Nabila Ananda Kloping Oen Sindrawati Parung, Raymond PK, Laskar Ronaa Nuqtho Hidayatullah Sukmajaya, William Putera Sulis Bayusentono Thalca Hamid William Putera Sukmajaya Yudhistira Pradnyan Kloping