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COMPARISON OF GLOMERULAR FILTRATION RATE IN DIABETIC NEPHROPATHY PATIENT WITH COMORBID HYPERTENSION AND MEDICATION ADHERENCE Jimmy Chua; Yohanes Firmansyah; Joshua Kurniawan; Ernawati Ernawati
Jurnal Medika Hutama Vol. 2 No. 03 April (2021): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Abstract

Background: Chronic Kidney Disease (CKD) is a global health problem with increasing prevalence and incidence of kidney failure, bad prognosis, and high treatment cost. The prevalence of CKD increases with the increasing number of elderly population and the incidence of diabetes mellitus and hypertension. Comorbidities of patient with CKD, according to Indonesian Renal Registry in 2018, are hypertension or uncontrolled blood pressure (51%) and type 2 diabetes mellitus (21%). Methods: Cross-sectional studies of patients in “RT” Hospital Jakarta between 2018-2019. The independent variable in this research is hypertension comorbidities and medication adherence, whereas glomerulus filtration rate as the dependent variable. the correlation of cause and effect is tested with Independent T-Test and Mann Whitney Test as an alternative. Findings: The research includes 26 respondents, with prevalence of hypertension in diabetic nephropathy patient of 17 (65,4%). Population of patient with diabetic nephropathy with hypertension comorbidities has lower glomerular filtration rate (GFR) compared with group of diabetic nephropathy patients without comorbid hypertension (14.4% vs 28.6%). Hypertensive patients with no routine treatment have average GFR of 8.5%, and hypertensive patients with routine treatment have GFR of 16.15%. Statistical test results with Mann Whitney shows that there are no meaningful difference in average GFR between the two groups (p-value: 0.130).Conclusion: Blood pressure control and medication adherence can slow down the decline in renal function caused by complication of diabetic nephropathy, although there are no meaningful relation found in this research because of lacking in samples.
Hubungan Obesitas dengan Kejadian Nyeri Lutut pada Lansia Nency Martaria; Joshua Kurniawan; Fernando Nahaniel; Noer Saelan Tadjudin
JURNAL FISIOTERAPI DAN ILMU KESEHATAN SISTHANA Vol. 5 No. 2 (2023): Juli : Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jufdikes.v5i2.377

Abstract

Obesity is one of commonly found problem, with the numbers rising globally. Obesity also often associated with other conditions, such as heart disease, stroke, diabetes, and osteoarthritis. This study aims to find out the correlation between obesity and incidence of knee pain for elderly. The study is an analytic observational study with cross-sectional design, that’s done at Sasana Tresna Werda RIA Pembangunan in January 2019. The population for this study is the elderly with minimum 60 years of age. Data were obtained through interview for knee pain variable, height and weight were measured by health workers using calibrated tools. Body mass index (BMI) over 25 kg/m2 is categorized as obese. Descriptive data will be presented as proportion (%). Statistical test used in the study are Pearson Chi Square with Yates Correction and Fisher Exact as alternative. The expected significance value in this study is 5%. The study found that there was significant relationship between obesity and knee pain in the elderly at Sasana Tresna Werda RIA Pembangunan (p-value=0.022). Elderly group with obesity is clinically known have 2.684 times higher riks of experiencing knee pain compared to the other group. Obesity is a major risk factor for knee pain including osteoarthritis and has an impact on morbidity in the elderly population. Holistic evaluation and treatment is needed in dealing with knee pain and obesity, considering that these two variables have a complex and multi-factorial pathogenesis.
Tumor-Like Mass in Patient with Tuberculosis : Is It Really a Malignancy? a Case Report Joshua Kurniawan; Annisa Ananda; Kasum Supriadi
Malahayati Nursing Journal Vol 5, No 8 (2023): Volume 5 Nomor 8 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v5i8.10964

Abstract

ABSTRACT Tuberculosis (TB) is not all about chronic cough or hemoptysis. The clinical manifestation of TB could be pulmonary and extrapulmonary, with the later defined as any site other than the lung, affected by the TB. The global burden for tuberculosis is still heavy, standing as the second leading infectious killer after COVID-19 (above HIV/AIDS), TB holds the 13th place of the leading cause of death. The World Health Organization (WHO) predicted around 1.6 million people died from TB, and 10.6 million people fell ill with TB worldwide in 2021. Due to the various manifestations and limitations of the diagnostic tools, determining the diagnosis and treatment of TB has always been a challenge since a long time ago. To give appropriate therapy, making an accurate diagnosis is crucial. It is known that extrapulmonary tuberculosis manifestation often mimics malignancy, both clinically and radiologically. The treatment for these cases should include treatment for the infection and the affected organ or site, following the recommended therapy dose and duration. Neurological examination should be evaluated, especially for tuberculosis of the spine. Surgical approach should be considered for cases with neurological deficits, patient with spine-at-risk, progressive spinal deformity, severe pain, spinal instability, or uncertain diagnosis. Physical therapy could be considered to improve respiratory function, improving muscle strength, reducing the pain, repair/improve the range of motion, sensory function, improve quality of life, and prevent other complications. Keywords: Extrapulmonary Manifestation, Mimics Malignancy, Tuberculosis
Pengaruh Kadar Profil Lipid, Asam Urat, Indeks Massa Tubuh, Tekanan Darah, dan Kadar Gula Darah Terhadap Penurunan Kapasitas Vital Paru pada Pekerja Usia Produktif Ernawati Ernawati; Eko Kristanto Kunta Adjie; Yohanes Firmansyah; Giovanno Sebastian Yogie; William Gilbert Setyanegara; Joshua Kurniawan
Malahayati Nursing Journal Vol 5, No 8 (2023): Volume 5 Nomor 8 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v5i8.10414

Abstract

ABSTRACT Decreased lung function is a common health problem that affects millions of people worldwide. The prevalence of decreased lung function in the general population has increased from 11.2% to 28.8% in individuals over the age of 50 years. The exact mechanism of these relationships is not fully understood. This study aims to determine the effect of obesity, hypertension, dyslipidemia, hyperuricemia, and diabetes mellitus on the decline in lung function among working-age workers. This research is a cross-sectional study carried out at the Kalam Kudus Foundation in the period of May 2023 involving productive age respondents aged 18 to 60 years. The minimum sample size required in this study is 50 respondents according to the rule of thumb formula. Descriptive data analysis in the form of centralized data distribution for quantitative data and proportion (%) for qualitative data. Analytical data analysis uses the Linear Regression method, enter method to see which factor has the strongest influence on the dependent variable. The results of the linear regression statistical test revealed that only the Low-Density Lipoprotein (LDL) level variable had a significant role in affecting lung vital capacity (OR: 0.433; p-value: 0.030). From the analysis results, it was found that LDL levels significantly affect the vital capacity of the lungs. Further research is needed to assess other factors that affect lung vital capacity. Keywords: Lung Vital Capacity, Lipid Profile, Uric Acid, BMI, Blood Pressure, Blood Glucose Level.  ABSTRAK Penurunan fungsi paru-paru adalah masalah kesehatan umum yang mempengaruhi jutaan orang di seluruh dunia. Prevalensi penurunan fungsi paru pada populasi umum mengalami peningkatan dari 11,2%, menjadi 28,8% pada individu di atas usia 50 tahun. Mekanisme yang tepat hubungan-hubungaan ini tidak sepenuhnya dipahami. Penelitian ini bertujuan untuk melihat bagaimana pengaruh dari obesitas, hipertensi, dislipidemia, hiperurisemia, dan diabetes mellitus terhadap penurunan fungsi paru di kalangan pekerja usia produktif. Penelitian ini merupakan penelitian potong lintang yang dilaksanakan di Yayasan Kalam Kudus pada periode bulan Mei 2023 dengan mengikutsertakan responden usia produktif berusia 18 hingga 60 tahun. Besar sampel minimum yang dibutuhkan pada penelitian ini adalah 50 responden berdasarkan rumus rule of thumb. Analisa data deskriptif berupa sebaran data terpusat untuk data kuantitatif dan proporsi (%) untuk data yang bersifat kualitatif. Analisa data analitik menggunakan metode Regresi Linear, enter method untuk melihat faktor mana yang memiliki pengaruh terkuat dalam mempengaruhi variabel tergantung. Hasil uji statistik regresi linear mengungkapkan bahwa hanya variabel kadar Low Density Lipoprotein (LDL) yang berperan signifikan dalam mempengaruhi kapasitas vital paru (OR: 0,433; p-value: 0,030). Dari hasil analisis didapat kadar LDL mempengaruhi kapasitas vital paru secara signifikan. Penelitian lebih lanjut diperlukan untuk menilai faktor lain yang mempengaruhi kapasitas vital paru. Kata Kunci: Kapasitas Vital Paru, Profil Lipid, Asam Urat, IMT, Tekanan Darah, Kadar Gula Darah