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COMPARISON OF GLOMERULAR FILTRATION RATE IN DIABETIC NEPHROPATHY PATIENT WITH COMORBID HYPERTENSION AND MEDICATION ADHERENCE Jimmy Chua; Yohanes Firmansyah; Joshua Kurniawan; Ernawati Ernawati
Jurnal Medika Hutama Vol. 2 No. 03 April (2021): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Background: Chronic Kidney Disease (CKD) is a global health problem with increasing prevalence and incidence of kidney failure, bad prognosis, and high treatment cost. The prevalence of CKD increases with the increasing number of elderly population and the incidence of diabetes mellitus and hypertension. Comorbidities of patient with CKD, according to Indonesian Renal Registry in 2018, are hypertension or uncontrolled blood pressure (51%) and type 2 diabetes mellitus (21%). Methods: Cross-sectional studies of patients in “RT” Hospital Jakarta between 2018-2019. The independent variable in this research is hypertension comorbidities and medication adherence, whereas glomerulus filtration rate as the dependent variable. the correlation of cause and effect is tested with Independent T-Test and Mann Whitney Test as an alternative. Findings: The research includes 26 respondents, with prevalence of hypertension in diabetic nephropathy patient of 17 (65,4%). Population of patient with diabetic nephropathy with hypertension comorbidities has lower glomerular filtration rate (GFR) compared with group of diabetic nephropathy patients without comorbid hypertension (14.4% vs 28.6%). Hypertensive patients with no routine treatment have average GFR of 8.5%, and hypertensive patients with routine treatment have GFR of 16.15%. Statistical test results with Mann Whitney shows that there are no meaningful difference in average GFR between the two groups (p-value: 0.130).Conclusion: Blood pressure control and medication adherence can slow down the decline in renal function caused by complication of diabetic nephropathy, although there are no meaningful relation found in this research because of lacking in samples.

Hubungan Obesitas dengan Kejadian Nyeri Lutut pada Lansia Nency Martaria; Joshua Kurniawan; Fernando Nahaniel; Noer Saelan Tadjudin
JURNAL FISIOTERAPI DAN ILMU KESEHATAN SISTHANA Vol. 5 No. 2 (2023): Juli : Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jufdikes.v5i2.377

Obesity is one of commonly found problem, with the numbers rising globally. Obesity also often associated with other conditions, such as heart disease, stroke, diabetes, and osteoarthritis. This study aims to find out the correlation between obesity and incidence of knee pain for elderly. The study is an analytic observational study with cross-sectional design, thatâ€™s done at Sasana Tresna Werda RIA Pembangunan in January 2019. The population for this study is the elderly with minimum 60 years of age. Data were obtained through interview for knee pain variable, height and weight were measured by health workers using calibrated tools. Body mass index (BMI) over 25 kg/m2 is categorized as obese. Descriptive data will be presented as proportion (%). Statistical test used in the study are Pearson Chi Square with Yates Correction and Fisher Exact as alternative. The expected significance value in this study is 5%. The study found that there was significant relationship between obesity and knee pain in the elderly at Sasana Tresna Werda RIA Pembangunan (p-value=0.022). Elderly group with obesity is clinically known have 2.684 times higher riks of experiencing knee pain compared to the other group. Obesity is a major risk factor for knee pain including osteoarthritis and has an impact on morbidity in the elderly population. Holistic evaluation and treatment is needed in dealing with knee pain and obesity, considering that these two variables have a complex and multi-factorial pathogenesis.

Tumor-Like Mass in Patient with Tuberculosis : Is It Really a Malignancy? a Case Report Joshua Kurniawan; Annisa Ananda; Kasum Supriadi
Malahayati Nursing Journal Vol 5, No 8 (2023): Volume 5 Nomor 8 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v5i8.10964

ABSTRACT Tuberculosis (TB) is not all about chronic cough or hemoptysis. The clinical manifestation of TB could be pulmonary and extrapulmonary, with the later defined as any site other than the lung, affected by the TB. The global burden for tuberculosis is still heavy, standing as the second leading infectious killer after COVID-19 (above HIV/AIDS), TB holds the 13th place of the leading cause of death. The World Health Organization (WHO) predicted around 1.6 million people died from TB, and 10.6 million people fell ill with TB worldwide in 2021. Due to the various manifestations and limitations of the diagnostic tools, determining the diagnosis and treatment of TB has always been a challenge since a long time ago. To give appropriate therapy, making an accurate diagnosis is crucial. It is known that extrapulmonary tuberculosis manifestation often mimics malignancy, both clinically and radiologically. The treatment for these cases should include treatment for the infection and the affected organ or site, following the recommended therapy dose and duration. Neurological examination should be evaluated, especially for tuberculosis of the spine. Surgical approach should be considered for cases with neurological deficits, patient with spine-at-risk, progressive spinal deformity, severe pain, spinal instability, or uncertain diagnosis. Physical therapy could be considered to improve respiratory function, improving muscle strength, reducing the pain, repair/improve the range of motion, sensory function, improve quality of life, and prevent other complications. Keywords: Extrapulmonary Manifestation, Mimics Malignancy, Tuberculosis

Pengaruh Kadar Profil Lipid, Asam Urat, Indeks Massa Tubuh, Tekanan Darah, dan Kadar Gula Darah Terhadap Penurunan Kapasitas Vital Paru pada Pekerja Usia Produktif Ernawati Ernawati; Eko Kristanto Kunta Adjie; Yohanes Firmansyah; Giovanno Sebastian Yogie; William Gilbert Setyanegara; Joshua Kurniawan
Malahayati Nursing Journal Vol 5, No 8 (2023): Volume 5 Nomor 8 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v5i8.10414

ABSTRACT Decreased lung function is a common health problem that affects millions of people worldwide. The prevalence of decreased lung function in the general population has increased from 11.2% to 28.8% in individuals over the age of 50 years. The exact mechanism of these relationships is not fully understood. This study aims to determine the effect of obesity, hypertension, dyslipidemia, hyperuricemia, and diabetes mellitus on the decline in lung function among working-age workers. This research is a cross-sectional study carried out at the Kalam Kudus Foundation in the period of May 2023 involving productive age respondents aged 18 to 60 years. The minimum sample size required in this study is 50 respondents according to the rule of thumb formula. Descriptive data analysis in the form of centralized data distribution for quantitative data and proportion (%) for qualitative data. Analytical data analysis uses the Linear Regression method, enter method to see which factor has the strongest influence on the dependent variable. The results of the linear regression statistical test revealed that only the Low-Density Lipoprotein (LDL) level variable had a significant role in affecting lung vital capacity (OR: 0.433; p-value: 0.030). From the analysis results, it was found that LDL levels significantly affect the vital capacity of the lungs. Further research is needed to assess other factors that affect lung vital capacity. Keywords: Lung Vital Capacity, Lipid Profile, Uric Acid, BMI, Blood Pressure, Blood Glucose Level. ABSTRAK Penurunan fungsi paru-paru adalah masalah kesehatan umum yang mempengaruhi jutaan orang di seluruh dunia. Prevalensi penurunan fungsi paru pada populasi umum mengalami peningkatan dari 11,2%, menjadi 28,8% pada individu di atas usia 50 tahun. Mekanisme yang tepat hubungan-hubungaan ini tidak sepenuhnya dipahami. Penelitian ini bertujuan untuk melihat bagaimana pengaruh dari obesitas, hipertensi, dislipidemia, hiperurisemia, dan diabetes mellitus terhadap penurunan fungsi paru di kalangan pekerja usia produktif. Penelitian ini merupakan penelitian potong lintang yang dilaksanakan di Yayasan Kalam Kudus pada periode bulan Mei 2023 dengan mengikutsertakan responden usia produktif berusia 18 hingga 60 tahun. Besar sampel minimum yang dibutuhkan pada penelitian ini adalah 50 responden berdasarkan rumus rule of thumb. Analisa data deskriptif berupa sebaran data terpusat untuk data kuantitatif dan proporsi (%) untuk data yang bersifat kualitatif. Analisa data analitik menggunakan metode Regresi Linear, enter method untuk melihat faktor mana yang memiliki pengaruh terkuat dalam mempengaruhi variabel tergantung. Hasil uji statistik regresi linear mengungkapkan bahwa hanya variabel kadar Low Density Lipoprotein (LDL) yang berperan signifikan dalam mempengaruhi kapasitas vital paru (OR: 0,433; p-value: 0,030). Dari hasil analisis didapat kadar LDL mempengaruhi kapasitas vital paru secara signifikan. Penelitian lebih lanjut diperlukan untuk menilai faktor lain yang mempengaruhi kapasitas vital paru. Kata Kunci: Kapasitas Vital Paru, Profil Lipid, Asam Urat, IMT, Tekanan Darah, Kadar Gula Darah

Hubungan Kadar HBA1C dan Insulin Puasa Terhadap Infeksi Saluran Kemih Pada Kelompok Lanjut Usia di Panti Santa Anna Donatila Mano S; Zita Atzmardina; Alexander Halim Santoso; Fernando Nathaniel; Joshua Kurniawan; Dean Ascha Wijaya; Eric Raditya Kaminto; Andini Ghina Syarifah; Pasuarja Jeranding Ezra; Agnes Marcella; Rifi Nathaznya Syachputri
Malahayati Nursing Journal Vol 6, No 7 (2024): Volume 6 Nomor 7 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i7.13510

ABSTRACT Urinary tract infection (UTI) poses a serious concern in the elderly population, with approximately 25% of total infection cases in the geriatric group being UTIs. Diabetes mellitus stands as a leading cause of global morbidity and is associated with severe complications, including an increased risk of infections impacting the quality of life. Patients with diabetes face a twofold higher risk of mortality due to infections. Advanced age is also a risk factor for UTIs, influenced by factors such as uncontrolled diabetes. Measuring parameters such as fasting insulin and HbA1c levels is crucial for understanding correlation between diabetes and UTIs. HbA1c can reflect long-term glycemic control in diabetic patients. This cross-sectional study aims to investigate relationship between HbA1c and fasting insulin levels concerning the occurrence of UTIs in the elderly population, conducted at the Santa Anna Nursing Home in 2023. The study included 33 respondents with an average age of 72.88 years, predominantly comprising 24 female respondents (72.7%). The mean fasting insulin level was 12.46 mIU/mL, and HbA1c level was 5.97%. UTIs were diagnosed in 11 respondents (33.3%). The correlation analysis between these variables indicated no significant difference in the mean HbA1c levels between groups with or without UTIs (p = 0.955). However, a significant difference was observed in the mean fasting insulin levels between the two groups (p 0.001). This finding is noteworthy as fasting insulin levels have a direct correlation with circulating blood glucose levels and formation of red blood cells, potentially influencing HbA1c levels. Further clarification is needed on how these three variables interact. Keywords: Elderly, Fasting Insulin, HbA1c, Urinary Tract Infection ABSTRAK Infeksi saluran kemih (ISK) adalah masalah serius pada populasi lanjut usia, sekitar 25% dari total kasus infeksi pada kelompok geriatri adalah ISK. Diabetes melitus adalah penyebab utama morbiditas global dan berhubungan dengan komplikasi serius, termasuk risiko infeksi yang berdampak pada kualitas hidup. Pasien diabetes memiliki risiko dua kali lipat lebih tinggi untuk kematian akibat infeksi. Peningkatan usia juga merupakan faktor risiko untuk ISK, yang dipengaruhi oleh faktor-faktor seperti diabetes yang tidak terkontrol. Pengukuran parameter seperti insulin puasa dan HbA1c adalah kunci dalam memahami korelasi antara diabetes dan ISK. HbA1c dapat mencerminkan kontrol glikemik jangka panjang pada pasien diabetes. Penelitian potong lintang ini bertujuan untuk mengetahui hubungan antara kadar HbA1c dan insulin puasa terhadap kejadian ISK pada kelompok lanjut usia yang dilakukan di Panti Lansia Santa Anna pada tahun 2023. Penelitian mengikutsertakan 33 responden dengan rata-rata usia 72,88 tahun dan didominasi oleh jenis kelamin perempuan sebanyak 24 responden (72,7%). Rerata kadar insulin puasa sebesar 12,46 mIU/mL dan kadar HbA1c sebanyak 5,97%. Sebanyak 11 responden (33,3%) terdiagnosis ISK. Hasil korelasi antara kedua variabel tersebut menunjukkan bahwa tidak ada perbedaan signifikan dalam rerata kadar HbA1c antara kelompok dengan atau tanpa ISK (p = 0,955). Meskipun demikian, terdapat perbedaan signifikan dalam rerata kadar insulin puasa antara kedua kelompok (p 0,001). Hal ini menjadi sebuah pertimbangan karena kadar insulin puasa memiliki korelasi langsung dengan jumlah gula yang beredar bebas dalam darah dan pembentukan sel darah merah yang dapat meningkatkan tingkat HbA1c. Diperlukan penjelasan lebih lanjut tentang bagaimana ketiga variabel ini berinteraksi. Kata Kunci: HbA1c, Infeksi Saluran Kemih, Insulin Puasa, Lanjut Usia

Hubungan Kadar Vitamin D dengan Kejadian Insomnia Pada Kelompok Lanjut Usia di Panti Santa Anna Anastasia Ratnawati Biromo; Noer Saelan Tadjudin; Alexander Halim Santoso; Yohanes Firmansyah; William Gilbert Satyanegara; Dean Ascha Wijaya; Joshua Kurniawan; Ayleen Nathalie Jap; Fladys Jashinta Mashadi; Melkior Michael Fransisco; Linginda Soebrata
Malahayati Nursing Journal Vol 6, No 7 (2024): Volume 6 Nomor 7 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i7.13516

ABSTRACT Vitamin D deficiency is a public health problem that affects everyone regardless of their age. It is linked to various health problems, and one of them is sleep problem. Nearly 60% of elderly have sleep problems, with insomnia being the most frequently reported symptom. Insomnia can lead to physical, mental, behaviour problems, and increasing risk of having diabetes and cardiovascular disease. To find the association between vitamin D and insomnia in elderly. This research uses cross sectional study to find association between vitamin D and insomnia in elderly who live in Santa Anna’s nursing home. Respondents who met the inclusion criterias were measured for vitamin D and then filling out Insomnia Severity Index (ISI) questionnaire. Statistical analysis used is the Mann-Whitney test. Twenty-seven participants met the inclusion criteria, with the mean age of 75,59 (SD 7,42) years and vitamin D level 19,93 (SD 6,87) ng/ml. There was no significant difference in vitamin D level between non-insomnia and insomnia (p-value 0,979). However, from this study we found that lower vitamin D serum was associated with the increasing risk of insomnia. Vitamin D deficiency should be taken into account when treating elderly with sleep disorder. Health practitioners should consider Vitamin D supplementation as adjunctive treatment in sleep problems. Keywords: Insomnia, Elderly, Vitamin D ABSTRAK Defisiensi vitamin D merupakan masalah kesehatan umum yang dapat terjadi pada semua orang tanpa memandang usia. Defisiensi vitamin D dihubungkan dengan berbagai macam masalah kesehatan, salah satunya adalah gangguan tidur. Gangguan tidur pada lansia merupakan masalah yang sering ditemui, dimana hampir 60% lansia mengalami gangguan tidur. Insomnia dapat menyebabkan gangguan fisik, mental, perilaku, dan meningkatkan risiko penyakit diabetes serta kardiovaskular. Meneliti hubungan vitamin D dengan kejadian insomnia pada lansia. Penelitian ini merupakan studi potong lintang yang mencari hubungan antara kadar vitamin D dengan kejadian insomnia pada orang lanjut usia di Panti Lansia Santa Anna. Responden yang memenuhi kriteria inklusi dilakukan pengukuran kadar vitamin D dan pengisian kuesioner Insomnia Severity Index (ISI) untuk insomnia. Analisis statistik dilakukan dengan menggunakan uji Mann-Whitney. Sebanyak 27 responden memenuhi kriteria inklusi dengan rerata usia 75,59 (SD 7,42) tahun, dengan kadar vitamin D 19,93 (SD 6,87) ng/ml. Hasil analisis statistik tidak mendapatkan perbedaan rerata kadar vitamin D yang bermakna antara kelompok dengan atau tanpa insomnia (p-value 0,979), meski demikian pada penelitian ini didapatkan bahwa defisiensi vitamin D berisiko meningkatkan terjadinya insomnia. Defisiensi vitamin D harus dipertimbangkan dalam manajemen lanjut usia dengan gangguan tidur. Suplementasi vitamin D dapat dipertimbangkan sebagai terapi tambahan pada lanjut usia yang mengalami gangguan tidur. Kata Kunci: Insomnia, Lansia, Vitamin D

Hubungan Kadar Insulin Puasa dengan Indeks Massa Tubuh Pada Kelompok Lanjut Usia di Panti Lanjut Usia Olivia Charissa; Alexander Halim Santoso; Joshua Kurniawan; Dean Ascha Wijaya; Fernando Nathaniel; Yohanes Firmansyah; Bryan Anna Wijaya; Gracienne Gracienne; Yovian Timothy Satyo; Steve Vallery Ranonto
Malahayati Nursing Journal Vol 6, No 7 (2024): Volume 6 Nomor 7 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i7.13126

ABSTRACT Elderly population is increasing globally. One of the global adversity is obesity. Prevalence of obesity in the elderly population is growing over time and has become a global threat. Obesity also affect insulin level and resistancy, becoming the foundation for diabetes melitus, the unending global health problem. This will bring various health risks for elderly. This study aims to find out the correlation between fasting insulin level with body mass index in the elderly population. This cross-sectional study was done in Santa Anna Nursing Home. The sampling method is total sampling. Body mass index data collection was carried out according to standard physical examination protocols and insulin level analysis was carried out according to standard laboratory protocols. Statistic analysis used in the study is Spearman correlation, with hoped significance level of 5% and power of 80%. We found 31 respondents with mean age of 73.1 (±9.55) years with female as the dominant gender. The median of insulin level were 10 (5,4 – 29,,5) uIU/mL, with mean BMI of 22,24 (3,95) kg/m2. Statistical analysis found no significant correlation between fasting insulin level with BMI (p-value : 0.179), but clinically could be seen that increase of fasting insulin level will affect the increase of BMI though its only a weak correlation (r-spearman : 0.248). Fasting insulin level plays a role and could affect body mass index in the elderly body. Keywords: Body Mass Index, Elderly, Fasting Insulin, Nursing Home ABSTRAK Jumlah penduduk lanjut usia secara global akan terus meningkat. Salah satu permasalahan yang mendunia adalah obesitas. Prevalensi obesitas pada populasi lanjut usia kian meningkat dan menjadi ancaman global. Obesitas juga memengaruhi kadar dan resistensi insulin yang menyebabkan diabetes melitus menjadi masalah kesehatan yang tak kunjung berakhir di dunia. Hal ini menjadi dasar berbagai risiko kesehatan pada lansia. Studi ini dilakukan untuk mengetahui apakah terdapat hubungan yang bermakna antara kadar insulin puasa dengan indeks massa tubuh pada kelompok lanjut usia. Studi cross-sectional ini dilaksanakan di Panti Lanjut Usia Santa Anna. Metode pengambilan sampel berupa total sampling. Pengambilan data indeks massa tubuh dilakukan sesuai protokol pemeriksaan fisik standar dan analisa kadar insulin dilaksanakan sesuai protokol laboratorium standar. Analisa statistik yang digunakan pada penelitian ini berupa analisa korelasi spearman, dengan nilai signifikansi yang diharapkan pada penelitian ini adalah sebesar 5% dengan kekuatan penelitian sebesar 80%. Didapatkan 31 responden dengan rerata usia sebesar 73,1 (±9,55) tahun dengan dominan berjenis kelamin perempuan (71,0%). Rerata kadar insulin puasa adalah 10 (5,4 – 29,,5) uIU/mL, dengan rerata IMT 22,24 (3,95) kg/m2. Pada uji statistik tidak didapatkan korelasi yang bermakna antara kadar insulin puasa dengan IMT (p-value : 0.179), tetapi secara klinis dapat terlihat bahwa peningkatan kadar insulin puasa akan berdampak terhadap peningkatan IMT walaupun tergolong dalam korelasi lemah (r-spearman : 0.248). Kadar insulin puasa tampak memegang peranan dan dapat berdampak terhadap indeks massa tubuh pada lansia. Kata Kunci: Indeks Massa Tubuh, Insulin Puasa, Lanjut Usia, Panti Lanjut Usia

Hubungan Kadar Insulin Puasa dengan Tekanan Darah Pada Kelompok Lanjut Usia: Studi Potong Lintang di Panti Santa Anna Robert Kosasih; Frisca Frisca; Alexander Halim Santoso; Yohanes Firmansyah; William Gilbert Satyanegara; Fernando Nathaniel; Joshua Kurniawan; Friliesa Averina; Daniel Goh; Ribkha Anggeline Hariesti Sitorus; Brian Albert Gaofman
Malahayati Nursing Journal Vol 6, No 7 (2024): Volume 6 Nomor 7 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i7.13127

ABSTRACT Hypertension is one of the most common causes of death in the world. Insulin is a hormone that has been studied for a long time, and hyperinsulinemia is a condition where the body requires large amounts of insulin to achieve normal sugar levels. It was found that hypertensive patients with metabolic syndrome disorders have higher insulin levels with or without obesity which makes it considered as a risk factor. Finding the correlation between fasting insulin and blood pressure in nuring home. Cross-sectional study research on the correlation of fasting insulin levels with blood pressure in the elderly group at Santa Anna Nursing house. Respondents who meet the inclusion criteria will follow a series of data collection according to applicable physical and laboratory examination standards. Statistical analysis using spearman correlation analysis. There were 30 respondents who met the inclusion criteria with an average age of 73 (56 - 88) years, systolic blood pressure (SBP) 120 (105-150) mmHg, diastolic blood pressure (DBP) 70 (55-80) mmHg, and fasting insulin levels 9.45 (5.4-29.5) μIU / ml. the results of the analysis did not find a significant correlation between fasting insulin levels and blood pressure (p-value = 0.590 and 0.898). In this study, it was found that the higher the fasting insulin level, the lower the systolic blood pressure (r-systolic = -0.102). Fasting insulin is one of the tests that can be carried out as an early detection of metabolic disease, especially as a prevention of hypertension. Keywords: Fasting Insulin, Elderly, Blood Presure ABSTRAK Hipertensi merupakan salah satu penyebab kematian tersering di dunia. Insulin merupakan hormon yang telah dipelajari sejak lama, dan hiperinsulinemia merupakan suatu kondisi dimana tubuh membutuhkan jumlah insulin yang banyak untuk mencapai kadar gula darah yang normal. Ditemukan bahwa pada penderita hipertensi dengan gangguan sindroma metabolik memiliki kadar insulin yang lebih tinggi baik itu dengan atau tanpa obesitas yang membuatnya dipertimbangkan sebagai faktor risiko. Meneliti bagaimana korelasi kadar insulin puasa dengan tekanan darah di panti lansia. Penelitian studi potong lintang mengenai korelasi kadar insulin puasa dengan tekanan darah pada kelompok lanjut usia di Panti Lansia Santa Anna. Responden yang memenuhi kriteria inklusi akan mengikuti rangkaian pengambilan data sesuai standar pemeriksaan fisik dan labotorium yang berlaku. Analisis statistik menggunakan analisis korelasi spearman. Terdapat 30 responden yang memenuhi kriteria inklusi dengan rerata usia 73 (56 – 88) tahun, tekanan darah sistolik (TDS) 120 (105-150) mmHg, tekanan darah diastolik (TDD) 70 (55-80) mmHg, dan kadar insulin puasa 9,45(5,4-29,5)μIU/ml. hasil analisis tidak didapatkan korelasi yang bermakna antara kadar insulin puasa dengan tekanan darah (p-value= 0,590 dan 0,898). Pada penelitian ini didapatkan semakin tinggi kadar insulin puasa maka akan semakin rendah tekanan darah sistolik (r-sistolik=-0,102). Insulin puasa merupakan salah satu pemeriksaan yang dapat dilakukan sebagai deteksi dini penyakit metabolik, khususnya sebagai pencegahan terhadap hipertensi. Kata Kunci: Insulin Puasa, Lansia, Tekanan Darah

Pengaruh Kadar High Density Lipoprotein (HDL) dan Usia terhadap Kejadian Peripheral Arterial Disease (PAD) Daniel Ruslim; Edwin Destra; Joshua Kurniawan; Yohanes Firmansyah
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 1 No. 3 (2023): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v1i3.2059

Peripheral arterial disease is a disease that will cause circulatory problem, causing reduction of blood flow inside the artery. This disease approximately has by 6.5 million people above 40 years of age in the United State, and is expected to double with each decade. There are many risk factors for this disease, which includes dyslipidemia and age. High-density lipoprotein (HDL) is one of the lipid component that affects dyslipidemia. This study aims to find out the effects of HDL and age to peripheral arterial disease incidence. The study was done in Yayasan Kalam Kudus, Jakarta on 02 June 2023, with the sample of people aged 18-60 years old, with non-randomized consecutive sampling method. The exclusion criteria on this study are respondents who refused to participate in the study, respondents who are amputated, respondents who has ulcer on the foot, and respondents with ankle-branchial index (ABI) above 1,3. The analysis done in this study are descriptive analysis as in proportion and distribution of centralized data, and analytic analysis using independent T-test and Mann Whitney test as an alternative test, with significance value of 5% (p-value = <0.05). Normality test was done before statistical analysis. From the study, we found out that age is significant role statistically in the incidence of peripheral arterial disease (p-value: 0.028), but levels of HDL are not statistically significant with the incidence of peripheral arterial disease (p-value: 0.084).

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