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All Journal Dentika Dental Journal Jurnal Teknosains Biomedical Engineering Majalah Kedokteran Gigi Indonesia
Rini Maya Puspita
Departemen Biomedika, Fakultas Kedokteran Gigi, Universitas Gajah Mada, Yogyakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology

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Journal : Biomedical Engineering

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The effects of regular exercise on the number of osteoclasts in ovariectomized Sprague dawley rat mandible Rini Maya Puspita
Biomedical Engineering Vol 1, No 1 (2015): BIOMEDICAL ENGINEERING
Publisher : Biomedical Engineering

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Abstract

Objective: This study aimed to examine the effect of regular exercise on the number of osteoclasts inovariectomized Sprague Dawley rat mandible.Methods: Eight female Sprague Dawley rats, 3 months of age, were ovariectomized and divided into control(untreated) and treatment group (regular exercise). The exercise conducted by the rats ran on a speciallydesigned rat treadmill for 12 weeks, 5 times per week, at a speed of 10-18 m/min for 60 minutes per day. At theend of the treatment, the mandible was taken and cleaned out from the tissue for making the histologicalpreparations with Hematoxylin and Eosin (HE) stain. The number of osteoclasts counted from each histologicalpreparation on 10 visual fields and the obtained data were analyzed using independent t-test.Result: The number of osteoclast was lower significantly in ovariectmized rats compared to control group (P <0.001).Conclusion: Regular exercise can decrease the number of osteoclasts in ovariectomized Sprague Dawley ratmandibles.
The effects of regular exercise on the number of osteoclasts in ovariectomized Sprague dawley rat mandibles Rini Maya Puspita; Fitrina Rachmadanty Siregar
Biomedical Engineering Vol 1, No 1 (2014)
Publisher : Biomedical Engineering

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Abstract

Objective: This study aimed to examine the effect of regular exercise on the number of osteoclasts in ovariectomized Sprague Dawley rat mandibles.Methods: Eight female Sprague Dawley rats, 3 months of age, were ovariectomized and divided into control (untreated) and treatment group (regular exercise). The exercise conducted by the rats ran on a specially designed rat treadmill for 12 weeks, 5 times per week, at a speed of 10-18 m/min for 60 minutes per day. At the end of the treatment, the mandible was taken and cleaned out from the tissue for making the histological preparations with Hematoxylin and Eosin (HE) stain. The number of osteoclasts counted from each histological preparation on 10 visual fields and the obtained data were analyzed using independent t-test.Result: The number of osteoclast was lower significantly in ovariectmized rats compared to control group (P < 0.001). Conclusion: Regular exercise can decrease the number of osteoclasts in ovariectomized Sprague Dawley rat mandibles.Key Words: mandibles; menopause; regular exercise; the number of osteoclasts;
Co-Authors Archadian Nuryanti Elastria Widita F. Fransiska Fitrina Rachmadanty Siregar Juni Handajani Regina TC. Tandelilin Rizki Amelia Rizki Amelia Rizki Amelia Tang Sze Mun