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All Journal Indonesia Natural Research Pharmaceutical Journal (INRPJ) Inaba of Community Services Journal
Dadih Supriadi
Universitas Bhakti Kencana
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences

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ARTIKEL REVIEW: PENGARUH PERLAKUAN PADA PATI SEBAGAI SUPERDISINTEGRAN TERHADAP WAKTU HANCUR FAST DISINTEGRATING TABLET Gina Novita; Dadih Supriadi; Fenti Fatmawati
INDONESIA NATURAL RESEARCH PHARMACEUTICAL JOURNAL Vol 6, No 1 (2021)
Publisher : Fakultas Farmasi Universitas 17 Agustus 1945 Jakarta

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Abstract

Pati banyak digunakan dalam formulasi Fast Disintegratating Tablet (FDT) sebagai superdisintegran karena biodegradabilitas dan biokompatibilitasnya, namun beberapa kekurangannya seperti kompresibilitas, sifat alir dan daya serap terhadap air yang rendah dapat membatasi aplikasinya seperti mempengaruhi keseragaman bobot, kesulitan dalam mengempa tablet dan waktu hancur tablet lebih lama. Berbagai modifikasi pati baik secara fisika, kimia, enzimatis maupun kombinasi dilakukan untuk meningkatkan efektivitas penggunaan pati. Tujuan review jurnal ini untuk memberikan informasi mengenai pengaruh perlakuan pada pati dari berbagai sumber sebagai superdisitegran terhadap waktu hancur FDT. Review jurnal ini dilakukan dengan metode literatur review. Pengumpulan data dilakukan melalui elektronik database PubMed dan Google cendekia. Pati hasil modifikasi memiliki permukaan granula pati lebih berpori berdasarkan hasil SEM dibandingkan pati alami. FDT menggunakan superdisintegran pati hasil modifikasi memiliki waktu hancur lebih cepat (<1 menit) dibandingkan pati alami (2-3 menit). Komposisi pati yang digunakan dalam formulasi FDT dapat mempengaruhi waktu hancur tergantung dari sumber pati dan modifikasi pati yang dilakukan. Modifikasi pati secara kimia diantaranya mengkombinasikan pati xanthate dan CMC Na memiliki waktu hancur 12 detik, modifikasi pati beras ikatan silang karboksimetil dengan sodium silikat memiliki waktu hancur 16,83 detik dan modifikasi pati dengan konjugasi glycine memiliki waktu hancur 19 detik merupakan formula yang paling efektif digunakan sebagai superdisintegran dalam formulasi Fast Disintegrating Tablet. 
Workshop Production of Liquid Soap Made from Arabica Coffee and Yogurt in Cibiru, Bandung to Develop Hygiene Lifestyle Ira Adiyati Rum; Dadih Supriadi; Dewi Kurnia; Yanni Dhiani Mardhiani; Kosasih Kosasih
Inaba of Community Services Journal Vol. 3 No. 1 (2024): Volume 3 No. 1, June 2024
Publisher : Universitas INABA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56956/inacos.v3i1.259

Abstract

Few communities in Cibiru have a problem, namely that they have not implement a clean and healthy lifestyle, namely the lack of the habit of washing hands with soap before eating, especially for children, resulting in moderate diarrhea in the community area, as well as a lack of post-harvest diversification of coffee and milk. The solution   provided is to educate the community by presentation about the importance of washing hands with soap before eating. This event also holds training in making liquid hand washing soap, so that people are skilled at making the product, and can even sell the product. There are three specific goals and targets to be achieved, namely the community gaining knowledge on how to make hand washing soap, the community get used to a clean and healthy lifestyle and increasing community income by selling the liquid soap. The methods that are used are presentation of material using in focus and Microsoft PPT, training in making hand-washing soap products (hands-on) and monitoring post-training product marketing. The method used to make this hand washing soap is the fermentation method for making yogurt, the maceration method for making Arabica coffee extract. From the results of the questionnaire evaluation, there was an increase in participants' insight after being given the training, namely from an average score of 68 to 90, so there is quantitative data on the results of this training
Co-Authors Dewi Kurnia Fenti Fatmawati Gina Novita IRA ADIYATI RUM Kosasih Kosasih Mardhiani, Yanni Dhiani