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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Oceana Biomedicina Journal Medica Hospitalia JOURNAL LA MEDIHEALTICO Journal of Social Research Oceana Biomedicina Journal Surabaya Biomedical Journal Jurnal Kedokteran Meditek Surabaya Biomedical Journal
Hendrata Erry Andisari
Fakultas Kedokteran Universitas Hang Tuah
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Recent Therapeutics Policies of Arthritis Rheumatoid (part I) Hendrata Erry Andisari
Oceana Biomedicina Journal Vol 1 No 1 (2018): Oceana Biomedicina Journal Vol 1 Issue (No) 1 January-June 2018
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v1i1.2

Abstract

Therapy in RA has undergone many advances today and in line with knowledge of the pathogenesis of RA, the current therapeutic goal is to alter the journey and control the activity of RA disease. Several groups of drugs have been used in RA therapy including non-steroidal anti-inflammatory drugs (NSAIDs), conventional diseasemodifying antirheumatic drugs (DMARDs) as well as biological agents (bDMARD), glucocorticoids and anti-pain medicines. In recent years, the development of biological agents that have specific targets for inflammatory mediators such as interleukin (IL) -1, IL-6 and Tumor Necrosis Factor (TNF) suggests a potent therapeutic effect on RA. In this article will be presented the latest biological agents as the latest therapy on RA.
PERKEMBANGAN TERKINI TERAPI RHEUMATOID ARTHRITIS (bagian 2) Hendrata Erry Andisari
Oceana Biomedicina Journal Vol 1 No 2 (2018): Oceana Biomedicina Journal Volume 1 Issue (No) 2 July - December 2018
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v1i2.14

Abstract

Therapy in RA has undergone many advances today and in line with knowledge of the pathogenesis of RA, the current therapeutic goal is to alter the journey and control the activity of RA disease. Several groups of drugs have been used in RA therapy including non-steroidal anti-inflammatory drugs (NSAIDs), conventional disease-modifying antirheumatic drugs (DMARDs) as well as biological agents (bDMARD), glucocorticoids and anti-pain medicines. In recent years, the development of biological agents that have specific targets for inflammatory mediators such as interleukin (IL) -1, IL-6 and Tumor Necrosis Factor (TNF) suggests a potent therapeutic effect on RA. In this article will be presented the latest biological agents as the latest therapy on RA.
Pengaruh Pemberian Terapi Oksigen Hiperbarik 2,4 ATA terhadap Kadar C-Reactive Protein (CRP) Darah Mencit Model Rheumatoid Arthritis Thalia Tamara; Hendrata Erry Andisari; Totot Mudjiono
Oceana Biomedicina Journal Vol 2 No 2 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 2 July - December 2019
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v2i2.33

Abstract

Background: Rheumatoid Arthritis (RA) is an autoimmune disease with an increasingprevalence from year to year. RA mortality continues to increase in the last 1 decade due tothe absence of effective prevention and therapy. Hyperbaric oxygen therapy can be anadjuvant therapy for Rheumathoid Arthritis.Objective: This study uses Hyperbaric Oxygen Therapy to reduce the inflammatory reactionin patients with Rheumatoid Arthritis.Method: Samples used are 16 male balb/c mice, divided into 2 groups, 1) group of inducedexperimental animals as models of Rheumatoid Arthritis 2) group of induced experimentalanimals as models of Rheumatoid Arthritis and given 3x30 minutes of 2.4 ATA hyperbaricoxygen therapy for 10 consecutive days. On 59th day, ELISA screening test is performed forC-ReactiveProtein measurement.Result: The average results of C-Reactive Protein levels between 2 groups, are, the group ofmice with rheumatoid arthritis model that was not treated with HBO therapy had an averageCRP level of 0.204 Pg / ml, while the group of mice with rheumatoid arthritis model which istreated with HBO therapy has a mean CRP level of 0.113 Pg / ml.Conclusion: There is an effect of hyperbaric oxygen therapy to C-Reactive Protein level inmice with rheumatoid arthritis model.
Seorang Penderita SLE dengan Emboli Paru Akut dan Hipertensi Pulmonal (Studi Kasus) Hendrata Erry Andisari; Gede Kambayana; Ketut Suega
Oceana Biomedicina Journal Vol 3 No 1 (2020): Oceana Biomedicina Journal Volume 3 Issue (No) 1 January - June 2020
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v3i1.31

Abstract

Kondisi Pulmonary embolism (PE) merupakan bagian dari spektrum penyakit yang disebut Venous thromboembolism (VTE). Seorang pasien dengan keluhan utama batuk yang mengeluarkan dahak berwarna keputihan datang ke RSUP Sanglah, Bali untuk mendapatkan terapi. Riwayat sebelumnya, pasien pernah dirawat inap di RSUP Sanglah tersebut.Saat ini diagnosis akhir pasien ini: SLE on treatment dengan moderate pulmonary hipertension dan suspek emboli paru, suspek pneumonia (HCAP) dengan severe sepsis dan syok sepsis, asidosis metabolik, observasi transaminitis ec reaktif dan hiponatremia kronik asimptomatik hipoosmoler euvolemic cb SIADH. Selanjutnya dilakukan tindakan terapi dan evaluasi terhadap terapi yang diberikan.
SEORANG PENDERITA HEPATITIS B AKUT BERAT, MUTAN “PRECORE”, GENOTIP C, YANG DITERAPI DENGAN ENTECAVIR MENGALAMI KECURIGAAN SINDROMA GIANOTTI-CROSTI Hendrata Erry Andisari
Oceana Biomedicina Journal Vol 6 No 2 (2023): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v6i2.111

Abstract

Introduction: The clinical course of HBV is very dynamic and difficult to predict, it can survive in the liver without causing clinical symptoms, or transform into a mutant form with clinical manifestations of severe acute hepatitis B (HBA) or fulminant hepatitis. Case: Patient Mr. AS, 22 years old, came to a private clinic (West Surabaya) on January 22, 2022. Due to yellow eyes, since 1 week before the patient has complained of weakness, lack of appetite, muscle and joint pain, and body aches. Conclusion: Entecavir therapy in Severe HBA is safe, provides clinical improvement, accompanied by clearing of HBV DNA and rapid anti-HBs seroconversion occurs.
Concomitant Colon Adenocarcinoma And Tuberculous Lymphadenitis Arya Abisatya, Albertus Magnus; Prameswari, Ajeng Andini; Fauzi, Agung Rahmat; Febrianto, Aji Pratama; Nugroho, Alexander Steven; Andisari, Hendrata Erry; Harijono, Pandu; Yudadi, Redemptus
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 3 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i3.1007

Abstract

BACKGROUND : Colon involvement in tuberculosis infection is a rare event. The coexistence of colon carcinoma and tuberculous lesions of the colon is less frequently reported. Carcinoma and tuberculosis of the colon can occur at the same site or at different sites. The occurrence of two pathologies at the same site is much less common. CASE PRESENTATION : A 52 year old woman complained of difficulty defecating, an enlarged stomach, pain and decreased appetite and weight loss within one month. On clinical examination, the abdomen appeared convex, slightly distended, and tenderness in the left lower iliac quadrant. Radiological examination supported the diagnose of partial obstructive ileus. The patient was diagnosed with adenocarcinoma of the ascending colon until the hepatic flexura was confirmed through surgery and histopathological examination. On histopathological examination, adenocarcinoma of the colon was found to coexistence with tuberculous lymphadenitis of the colon. CONCLUSION : The etiological and pathophysiological relationship between tuberculous lymphadenitis and colon cancer is still under debate, but surgeons need to be aware of this occurrence, to choose treatment and avoid post-operative worsening.
Effect of Noni Fruit (citrifolia L.) on Blood Glucose Levels of Male Diabetic Rattus Norvegicus Rats Wijaya, Caroline Shereen Aurelia; Andisari , Hendrata Erry; Risma, Risma
Journal La Medihealtico Vol. 4 No. 5 (2023): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v4i5.984

Abstract

Diabetes is a persistent metabolic disorder characterized by disruptions in both insulin secretion and action, leading to heightened blood glucose levels (hyperglycemia). Noni fruit, rich in antioxidant compounds like flavonoids and alkaloids, is thought to possess anti-diabetic properties. This study aimed to assess the influence of administering 500 mg/kgBW of noni fruit on the glucose levels of Wistar rats induced with diabetes using 150 mg/kgBW of alloxan. Blood sampling followed a post-test only group method conducted before terminating the mice. The study involved 33 mice divided into three groups: a negative control group, a positive control group induced with diabetes for 3 days, and a treatment group induced with diabetes followed by a 14-day administration of noni fruit extract. The normality test revealed a non-normal distribution with a p value <0.05. Additionally, the Kruskal-Wallis test resulted in a p value <0.05, signifying the impact of noni fruit administration on the blood glucose levels of rats. The Mann-Whitney U test indicated a p value > 0.05 between the positive control group and the treatment group. Despite the absence of a significant difference in glucose levels between the two groups, the study concluded that administering noni fruit at a dose of 500 mg/kgBW could influence the blood glucose levels of mice.
PENGARUH LATIHAN RENANG INTENSITAS SUBMAKSIMAL TERHADAP KADAR GLUKOSA DARAH TIKUS PUTIH BETINA KELOMPOK TERLATIH DAN TIDAK TERLATIH Alexander, Michael; Dagradi, Eric Mayo; Andisari, Hendrata Erry
Surabaya Biomedical Journal Vol 4 No 1 (2024): September
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v4i1.118

Abstract

Olahraga adalah kegiatan fisik yang dilakukan untuk meningkatkan kesehatan tubuh. Dengan meningkatnya jumlah masyarakat yang berolahraga, penting untuk memahami batasan intensitas olahraga yang dilakukan. Intensitas olahraga yang melampaui kemampuan tubuh akan menyebabkan munculnya stres oksidatif. Stres oksidatif akan menimbulkan berbagai masalah fisiologis tubuh, termasuk metabolisme glukosa. Jenis penelitian adalah eksperimental laboratoris. Tikus putih (Rattus norvegicus) betina galur Wistar usia 2 bulan dengan berat badan 180-200 gram dikelompokkan ke dalam 5 kelompok melalui teknik random sampling. K1 merupakan kontrol, K2 diberi latihan setiap hari selama 2 minggu, K3 diberi latihan sekali seminggu selama 2 minggu, K4 diberi latihan setiap hari selama 2 minggu, dan K5 diberi latihan sekali seminggu selama 2 minggu. Semua kelompok setelahnya diistirahatkan selama 1 minggu. K1, K2, dan K3 tidak diberi intervensi. K4 dan K5 diberi intervensi latihan submaksimal 85% rerata waktu tenggelam pertama. Penelitian diterminasi dan dilakukan pengambilan sampel untuk pengujian kadar glukosa darah acak. Hasil kadar glukosa darah acak diolah statistik dengan uji parametrik one-way Anova dan uji post hoc LSD. Hasil kadar glukosa darah (K1) 127,8 mg/dL, (K2) 133,4 mg/dL, (K3) 186,4 mg/dL, (K4) 160,6 mg/dL, dan (K5) 140,6 mg/dL. Uji one-way Anova menunjukkan perbedaan signifikan (p<0,05). Uji post hoc LSD menunjukkan tidak ada perbedaan bermakna antara kelompok terlatih dengan intervensi dan tidak terlatih dengan intervensi (p>0,05). Intervensi latihan submaksimal setelah istirahat satu minggu pada kelompok terlatih dan tidak terlatih dengan latihan submaksimal tidak memiliki pengaruh terhadap kadar glukosa darah tikus putih (Rattus norvegicus) betina galur Wistar.
PENGARUH LATIHAN RENANG INTENSITAS SUBMAKSIMAL TERHADAP KADAR GLUKOSA DARAH TIKUS PUTIH BETINA KELOMPOK TERLATIH DAN TIDAK TERLATIH Alexander, Michael; Dagradi, Eric Mayo; Andisari, Hendrata Erry
Surabaya Biomedical Journal Vol. 4 No. 1 (2024): September
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v4i1.118

Abstract

Olahraga adalah kegiatan fisik yang dilakukan untuk meningkatkan kesehatan tubuh. Dengan meningkatnya jumlah masyarakat yang berolahraga, penting untuk memahami batasan intensitas olahraga yang dilakukan. Intensitas olahraga yang melampaui kemampuan tubuh akan menyebabkan munculnya stres oksidatif. Stres oksidatif akan menimbulkan berbagai masalah fisiologis tubuh, termasuk metabolisme glukosa. Jenis penelitian adalah eksperimental laboratoris. Tikus putih (Rattus norvegicus) betina galur Wistar usia 2 bulan dengan berat badan 180-200 gram dikelompokkan ke dalam 5 kelompok melalui teknik random sampling. K1 merupakan kontrol, K2 diberi latihan setiap hari selama 2 minggu, K3 diberi latihan sekali seminggu selama 2 minggu, K4 diberi latihan setiap hari selama 2 minggu, dan K5 diberi latihan sekali seminggu selama 2 minggu. Semua kelompok setelahnya diistirahatkan selama 1 minggu. K1, K2, dan K3 tidak diberi intervensi. K4 dan K5 diberi intervensi latihan submaksimal 85% rerata waktu tenggelam pertama. Penelitian diterminasi dan dilakukan pengambilan sampel untuk pengujian kadar glukosa darah acak. Hasil kadar glukosa darah acak diolah statistik dengan uji parametrik one-way Anova dan uji post hoc LSD. Hasil kadar glukosa darah (K1) 127,8 mg/dL, (K2) 133,4 mg/dL, (K3) 186,4 mg/dL, (K4) 160,6 mg/dL, dan (K5) 140,6 mg/dL. Uji one-way Anova menunjukkan perbedaan signifikan (p<0,05). Uji post hoc LSD menunjukkan tidak ada perbedaan bermakna antara kelompok terlatih dengan intervensi dan tidak terlatih dengan intervensi (p>0,05). Intervensi latihan submaksimal setelah istirahat satu minggu pada kelompok terlatih dan tidak terlatih dengan latihan submaksimal tidak memiliki pengaruh terhadap kadar glukosa darah tikus putih (Rattus norvegicus) betina galur Wistar.
Hubungan Antara Lama Hemodialisis Dengan Red Cell Distribution Width (RDW) Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis di Rumah Sakit Pusat Angkatan Laut Dr. Ramelan Surabaya Semara, Putu Bagus Aditya Putra; Herjunianto2, Herjunianto; Andisari, Hendrata Erry
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i9.16334

Abstract

Penyakit Ginjal Kronis (PGK) merupakan masalah kesehatan yang makin berkembang secara global dan membutuhkan terapi pengganti ginjal. Red cell Distribution Width (RDW) merupakan suatu penanda kuantitatif dari variabilitas ukuran eritrosit. Peningkatan RDW menandakan adanya peningkatan variasi ukuran sel darah merah. Penelitian bertujuan untuk mengetahui hubungan antara lama hemodialisis dengan peningkatan Red Cell Distribution Width (RDW) pasien penyakit ginjal kronis yang menjalani hemodialisis di RSPAL Dr. Ramelan Surabaya. Penelitian ini menggunakan metode cross sectional dengan desain penelitian observasional analitik. Teknik pengambilan sampel adalah purposive sampling dengan jumlah sampel 64 pasien PGK yang menjalani HD di RSPAL Dr. Ramelan Surabaya. Pengambilan data menggunakan data sekunder yaitu rekam medis. Analisis data menggunakan uji korelasi Pearson untuk mengetahui hubungan kedua variabel. Hasil Penelitian menunjukan 64 pasien memenuhi kriteria inklusi, terdiri dari laki-laki 39(61%) orang dan perempuan 25(39%) orang, dengan rerata umur 53,68±9,54 tahun, rerata lama hemodialisis yang dijalani pasien adalah 10,22±12,29 bulan, dan rerata nilai RDW_CV adalah 15,13±2,36%. Dari hasil uji korelasi Pearson diperoleh koefisien korelasi 0,046 dengan nilai signifikansi (p) = 0,715. Nilai signifikansi (p) 0,715 > (α) 0,05 menunjukan tidak ada hubungan signifikan antara lama hemodialisis dengan peningkatan RDW pasien PGK yang menjalani HD di RSPAL Dr. Ramelan Surabaya. Dari penelitian ini disimpulkan bahwa, tidak didapatkan korelasi antara lama HD dengan RDW pasien PGK yang menjalani HD. Nilai RDW pasien PGK yang mejalani HD didapatkan rerata yaitu 15,13%. Lama HD yang dilaksanakan pasien PGK di RSPAL Dr. Ramelan Surabaya didapatkan rerata yaitu 10,22 bulan.
Co-Authors Amiril Mu’minin Angela Puspita Arya Abisatya, Albertus Magnus Eric Mayo Dagradi Fauzi, Agung Rahmat Febrianto, Aji Pratama Gede Kambayana Handajani, Fitri Herjunianto I Wayan Suryajaya Iswara, Karisma Kasih Ketut Suega Michael Alexander Nugroho, Alexander Steven Pandu Harijono Prameswari, Ajeng Andini Redemptus Yudadi Risma Risma, Risma Semara, Putu Bagus Aditya Putra Sherina Ayu Pitaloka Silvia Reynata Fauzia Sonia Kartika Ayu Soraya Nur Fajrina Stefani Irene Darmanto Tamara, Thalia Tan Wulan Pakungwati Thalia Tamara Totot Mudjiono Wijaya, Caroline Shereen Aurelia