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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) International Journal of Biosciences and Biotechnology Buletin Udayana Mengabdi Ecotrophic, Journal of Environmental Science Journal of Science and Applicative Technology Chimica et Natura Acta ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Media Sains Journal of Multidisciplinary Applied Natural Science Jurnal Ilmu Pendidikan Indonesia

N. W. Bogoriani

Program Studi Kimia FMIPA Universitas Udayana, Jimbaran, Bali, Indonesia

Author-ID : 4423114

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Physics

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Asupan Glikosida Flavonoid Terong Belanda (Solanum betaceum Cav.) Terhadap Aktivitas Superoksida Dismutase Dan Kadar Malondialdehid Tikus Wistar Yang Diberi Aktivitas Fisik Maksimal Jeane, Magda; Astiti Asih, Ida Ayu Raka; Bogoriani, Ni Wayan
Jurnal Media Sains Vol 2, No 1 (2018): JURNAL MEDIA SAINS
Publisher : LPPM Universitas Dhyana Pura

ABSTRAKTujuan dari penelitian ini adalah untuk mengetahui pengaruh asupan glikosida flavonoid terong belanda (Solanum betaceum Cav.) terhadap aktivitas Superoksida Dismutase (SOD) darah tikus Wistar yang diberi aktivitas fisik maksimal. Sampel penelitian adalah 24 ekor tikus yang dibagi kedalam 4 kelompok perlakuan yaitu: kontrol negatif, kontrol positif, pemberian ekstrak etanol, dan pemberian fraksi n-butanol. Aktivitas SOD diukur menggunakan kit Biovision. Hasil penelitian menunjukkan bahwa perlakuan yang diberikan memberikan perbedaan yang signifikan (p<0,05) terhadap aktivitas SOD. Pemberian glikosida flavonoid fraksi n-butanol meningkatkan aktivitas SOD tikus Wistar yang diberikan aktivitas fisik maksimal sebanyak 22,79% lebih tinggi dibandingkan pemberian asupan ekstrak etanol terong belanda. Keyword : Solanum betaceum Cav., Superoksida Dismutase, Aktivitas fisik, stres oksidatifABSTRACTThis study was conducted to determine the effect of flavonoid glycoside of Tamarillo (Solanum betaceum Cav.) on the activity of Wistar rat?s blood Superoxide Dismutase (SOD) enzyme provided maximum physical activity. Twenty four rats divided into 4 groups; negative control, positive control, ethanol extract, and n-butanol fraction. Superoxide Dismutase Enzyme activity was measured using Biovision kit. Results showed that the treatments gave significant difference (p<0.05) to SOD. Flavonoid glycoside from n-butanol fraction increased SOD activity of Wistar rat 22,79% higher than ethanol extract. Keyword : Solanum betaceum Cav., Superoxide Dismutase, Physical activity, oxidative stress

Potensi Ekstrak Metanol Daun Andong Merah (Cordyline Fruticosa (L.) A Chev.) dalam Menurunkan Kadar Asam Lemak Bebas dan Glukosa Darah pada Tikus Obesitas Mahayani, Putu Ayu Erna; Bogoriani, Ni Wayan; Bawa Putra, Anak Agung
Jurnal Media Sains Vol 3, No 1 (2019): JURNAL MEDIA SAINS
Publisher : LPPM Universitas Dhyana Pura

ABSTRAKTelah dilakukan uji aktivitas ekstrak metanol daun andong merah (Cordyline fruticosa (L.) A Chev.) dalam menurunkan kadar glukosa darah dan asam lemak bebas pada tikus wistar betina yang obesitas. Hasil uji fitokimia menunjukkan bahwa ekstrak mengandung senyawa polifenol, flavonoid, saponin, alkaloid, dan steroid. Hasil uji kadar glukosa dan asam lemak bebas menunjukkan bahwa pemberian ekstrak dosis 35mg/kg BB dan 70mg/kg BB dapat menurunkan kadar glukosa darah dan asam lemak bebas dibandingkan dengan kelompok tikus yang hanya diberi pakan tinggi lemak dengan perbedaan nyata p<0,05.Kata kunci: asam lemak bebas, Cordyline fruticosa (L.) A Chev., glukosa darah, obesitasABSTRACTThe activity of methanol extract of red andong leaf (Cordyline fruticosa (L.) A Chev.) to decrease blood glucose level and free fatty acid were investigated in obese female wistar rats. The results of phytochemical tests showed that the extract contains polyphenolic, flavonoid, saponin, alkaloid, and steroid compounds. The results of glucose and free fatty acid test showed that giving of extract with dose 35mg / kg BW and 70mg / kg BW could decrease blood glucose level and free fatty acid compared to the group of wistar rats were fed high fat with significant difference p <0,05.Keywords: blood glucose, Cordyline fruticosa (L.) A Chev., free fatty acid, obesity

Co-Authors A. A. Bawa Putra A. Intan Saridewi Abd. Rasyid Syamsuri Adnyana , I Made Dwi Mertha Anak Agung Istri Agung Mayun Laksmiwati Dwi Cahya Putra I M E. P. Siregar I M, Sukadana I Nengah Wirajana I Wayan Suirta I. A. R. Astiti Asih Jeane, Magda Mahayani, Putu Ayu Erna Miftakul Sururi N. M. T. Juliasari Ni Komang Ariati Ni Luh Gede Sudaryati Ni Luh Rustini Ni Luh Utari Sumadewi Ni Made Puspawati Ni Made Suaniti Ni Pt. Pande Mirah Surya Dewi Ni Putu Diantariani Nur Hafsia P. P. Dewi P. Suarya Putu Lakustini Cahyaningrum Putut Dewantha Jenar Sri Rahayu Santi Sri Wahjuni Sri Wardani

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