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All Journal Program Kreativitas Mahasiswa - Penelitian Chemistry Education Review
Anugrah Pratama
Kimia, MIPA, Universitas Halu Oleo
Chemistry

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UJI AKTIVITAS SENYAWA TURUNAN TERPENOID, STEROID DAN FENOLIK DARI EKSTRAK JARINGAN KAYU BATANG TUMBUHAN NDOKULO (Kleinhovia hospitaL.) TERHADAP PERTUMBUHAN SEL KANKER (Leukemia P-388) Nurhidayah, Nurhidayah; Minarti, Minarti; Pratama, Anugrah; Imran, Imran
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.152 KB)

Abstract

Research on this activity test aiming to determine the bioactivity and toxicity properties of compounds derived terpenoids, steroids and phenolic heartwood of plant tissue extracts Ndokulo (Kleinhovia hospita L.) on the growth of cancer cells (leukemia P-388). The method used is, sampling plant stem of Ndokulo, preparation, maceration, evaporation, extraction, fractionation, and activity test against Artemia salina and cancer cell. The main Component from n-hexane extract of the heartwood of this plant is β-sitosterol compound. The test against A. salina has the same tendency as the test of murine leukemia cells P-388 so that the primary test to measure the toxicity of the sample A. salina is proportional to the secondary test by measuring sample cytotoxicity against murine leukemia cells P-388. The measurements showed that the extracts have bioactivity against Artemia salina and potentially inhibit cancer cells growth. Keywords : Terpenoids, steroids, phenolic,  artemia salina, leukemia P-388.
Pengembangan e-LKPD Berbasis Model Discovery Learning pada Materi Pokok Asam Basa Pratama, Anugrah; Gani, Tabrani; Danial, Muhammad
Chemistry Education Review (CER) Volume 5 Nomor 1 September 2021
Publisher : Program Pasca Sarjana UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.324 KB) | DOI: 10.26858/cer.v5i1.26363

Abstract

This study aims to: (1) determine the process of developing e-LKPD based on the discovery learning model on acid and base materials to improve learning outcomes. (2) determine the level of validity, practicality and effectiveness of e-LKPD based on discovery learning models on acid and base materials to improve learning outcomes. This type of research is Research and Development (R&D). This development research procedure follows the ADDIE model which consists of 5 phases, namely: analysis, design, development, implementation, and evaluation. The results showed that the level of validity of the e-LKPD based on the discovery learning model on the average acid and base material was stated to be very valid and feasible to use. This is based on the results of validation by expert validators with a general validation value of 3.50 or a very valid category. The practicality of the e-LKPD media with the discovery learning model is stated to be practical with a presentation of around 70% - 100%. The e-LKPD media with the discovery learning model is very effective to use. Completeness or achievement of the pretest KKM or those who scored 75 and above were 5 people (13.89%) and increased to 36 student (100%). The developed e-LKPD media contains, (1) title cover, (2) KD and Learning Indicators, (3) brief material, (4) stimulus video, (5) problem formulation column, (6) observation column, (7 ) conclusion column.
Co-Authors Imran Gaffar Minarti Minarti Muhammad Danial Nurhidayah Nurhidayah Sangayu Ketut Laksemi Nilotama Tabrani Gani Yusuf Affendi Djalari, Yusuf Affendi