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All Journal Jurnal Farmasi Andalas Jurnal Sains dan Teknologi Farmasi
Syed Wasif Gillani
School of Pharmaceutical Sciences, Universiti Sains Malaysia
Computer Science & IT Education Medicine & Pharmacology

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Adverse Drug Reactions Among End-Stage Renal Failure Patients ec Diabetes Mellitus in General Hospital Pulau Pinang-Malaysia Fitria, Najmiatul; Gillani, Syed Wasif
Jurnal Farmasi Andalas Vol 1, No 1 (2013)
Publisher : Jurnal Farmasi Andalas

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Our study aimed at evaluating Adverse Drug Reactions (ADRs) among chronic kidney disease patients at the End-Stage Renal Failure (ESRF) secondary to Diabetes Mellitus. Retrospective cross-sectional study was used as the method of this study..Naranjo Scale was used to observe ADRs among  patients. Statistical analysis was done using statistical package of social sciences (SPSS 17®). Ethical clearance was done with respective clinical research committee. Study findings presents from 200 patients, 5.5% have probable, 15% possible and 79.5% doubtful ADRs. Hypoglycemia (2.5%) had the highest number of probable ADR. Insulin (1.5%) and gliclazid (1%) were the major cause of probable ADRs. Analysis showed significant correlation (sig.<0.05) between age and ESRF secondary to diabetes mellitus. Patient with ESRF secondary to diabetes mellitus above 55 years are tend to have ADRs. Analysis also showed no significant correlation (sig.>0.05) between adverse drug reactions and ESRF patients secondary to diabetes mellitus. 
Perbandingan Sosiodemografi End Stage Renal Failure Yang Disebabkan oleh Diabetes Mellitus dan Hipertensi Fitria, Najmiatul; A, Almahdy; Gillani, Syed Wasif
Jurnal Sains dan Teknologi Farmasi Vol 16 No 2 (2011)
Publisher : Fakultas Farmasi Universitas Andalas

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Our study aimed at evaluating sociodemographic value between diabetes mellitus and hypertension as the main cause of end-stage renal failure. Retrospective cross-sectional study was used as the research method. Two hundred end-stage renal failure patient records at 2010 were used to evaluate this study. Statistical analysis was done using statistical package of social sciences (SPSS 17®). Ethical clearance was issued by respective clinical research committee. Sociodemographic factors included gender, age, race, education and lifestyle. Results showed that from 200 end-stage renal failure patients there were 1% secondary to diabetes mellitus, 26.5% secondary to hypertension and 44% secondary to diabetes mellitus and hypertension. Case of end-stage renal failure in male secondary to diabetes mellitus (39%) was higher than hypertension (23.5%). End-stage renal failure secondary to diabetes mellitus was higher than hypertension (14%) in female. 33.5% patients were smokers, 22% were end-stage renal failure secondary to diabetes mellitus and the rest were secondary to hypertension. Statistical analysis showed no significant correlation (sig.>0.05) between lifestyle and end-stage renal failure secondary to diabetes mellitus and hypertension.
Co-Authors Almahdy A Najmiatul Fitria