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Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review Firmansyah, Tio; Saraswati, Utami; Ilham, Kurniadi; Jannatan, Robby; maliza, rita
Bioeksperimen: Jurnal Penelitian Biologi Vol 10, No 1: March 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v10i1.23534

Abstract

The continuous cell line known as T47D cells originates from the isolation of epithelial cells from the ductal breast tissue of a 54-year-old woman with metastatic breast cancer. Numerous plant species have been employed in alternative anti-breast cancer therapy, showing advancements in recent years. The aim of this systematic review is to assess the potential bioactive compounds from herbal plant extracts and analyze the effects of herbal plants on T47D breast cancer cells. This research employs a systematic approach to gather articles, encompassing related research questions, chosen databases, keyword selection, inclusion and exclusion criteria, as well as outcomes and conclusions regarding the collected articles. From the reviewed articles, several plants exhibit anti-breast cancer activity on T47D cell lines, namely Calamintha incana, Sterculia quadrifida, Psidium guajava, Uncaria nervosa, Syzygium aqueum, Capsicum annum, Bauhinia scandens, Lansium domesticum, and Garcinia cowa due to their content of bioactive compounds such as triterpenoids, alkaloids, phenolics, flavonoids, saponins, and tannins. These bioactive compounds from the plants exert significant influence on cell cycle, proliferation, fatty acid synthesis, and apoptosis of cancer cells.
EDUKASI DAN PEMBERDAYAAN KELOMPOK TANI SAWIT KABUPATEN DHARMASRAYA MELALUI PEMANFAATAN KUMBANG ELAEIDOBIUS KAMERUNICUS UNTUK MENINGKATKAN PRODUKTIVITAS DAN KESEJAHTERAAN MASYARAKAT Martinsyah, Rachmad Hersi; Ramadhan, Nugraha; Obel, Obel; Rezki, Dewi; Suhendra, Dede; Jannatan, Robby; Ronaldi, Ronaldi; Siswandra, Diko Okta; Diansyah, Rohan
Jurnal Abdi Insani Vol 12 No 11 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i11.3286

Abstract

This community service activity aimed to enhance the knowledge, skills, and awareness of oil palm farmers regarding the crucial role of the pollinating weevil Elaeidobius kamerunicus in supporting the natural and sustainable increase of oil palm fruit productivity. Currently, the low productivity of smallholder oil palm farms is generally caused by suboptimal pollination processes, a lack of farmer understanding of the biology and life cycle of pollinating insects, and the limited application of environmentally friendly technologies. The implementation methods of this service included counseling, interactive discussions, and field demonstrations on the identification, conservation, and utilization strategies of E. kamerunicus in oil palm plantations. The activity results showed an increase in farmer knowledge by 76.92% (based on pre-test and post-test), improved farmer skills in recognizing and preserving the habitat of the pollinating weevil, and the growth of collective awareness to reduce the use of pesticides that potentially harm pollinator insect populations. The long-term impact of this program is expected to increase oil palm fruit productivity, strengthen the economic resilience of farmers, and support the realization of more environmentally friendly and sustainable oil palm cultivation practices. Thus, this education and empowerment activity makes a real contribution to improving the welfare of oil palm farming communities while preserving the plantation agroecosystem.  
Enhanced Oviposition Preferences and Larval Performance of Hermetia illucens L. in Fruit Wastes Fermented by Effective Microorganisms Rahayu, Resti; Jannatan, Robby; Ronaldo, Muhamad; Muslima, Risa Ukhti
Makara Journal of Science Vol. 29, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Organic waste comprises a considerable portion of global waste, requiring effective management. The ability of the black soldier fly (Hermetia illucens, BSF) to convert organic waste into biomass has been well reported. However, bioconversion can be hindered by fiber-rich substrates, a challenge that can be addressed through substrate pretreatment. This study examined the oviposition preferences and larval performance of BSFs in several fruit wastes fermented by effective microorganisms (EMs), which were compared to non-fermented substrates. The oviposition attractants utilized pineapple peel and overripe soursop, with larval performance evaluated among different treatments, i.e., non-fermented pineapple peel (NFP), fermented pineapple peel (FP), non-fermented pineapple peel plus coconut endosperm waste (NFPC), and fermented pineapple peel plus coconut endosperm waste (FPC). Measured parameters included larval biomass, substrate consumption, the waste reduction index (WRI), and adult emergence. The result indicated that fermented pineapple peel produced the highest number of eggs among the oviposition attractant treatments. Larval biomass was highest in FP, while substrate consumption, WRI, and adult emergence rates were comparable between FP and FPC. Overall, the fermented substrates outperformed the non-fermented substrates across all parameters. These findings confirmed that fermentation with EMs enhances the utilization of fruit waste as an oviposition attractant and improves the performance of BSF bioconversion.
Implementasi Praktikum Biologi Berbasis Teknologi untuk Peningkatan Kompetensi Siswa dan Guru di SMU N 15 Padang Rita Maliza; Muhammad Idris; Ashrifurrahman Ashrifurrahman; Arthauly Yopita Sinurat; M.Nazri Janra; Nofrita Nofrita; Muhammad Syukri Fadil; Robby Jannatan; Mansyurdin Mansyurdin; Wilson Novarino; Kurniadi Ilham; Putra Santoso; Henny Herwina; Bramadi Arya; Tasya Putri Pratama Elisa; Reziq Marchellino Irwan
Buletin Dharmas Andalas Vol. 3 No. 1 (2026): Buletin Dharmas Andalas
Publisher : Departemen Budidaya Tanaman Perkebunan, Fakultas Pertanian, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bda.v3i1.60

Abstract

This community service activity was conducted on October 27, 2025, at SMA Negeri 15 Padang, with the aim of enhancing the competencies of teachers and students in biotechnology through the integration of modern technology as part of the digital transformation of education. The methods employed included direct training and mentoring, supported by a guidebook entitled “Basic Biology and Biotechnology: From Microscope to DNA.” The activity was organized into several thematic groups, namely plant and animal tissue histology, animal anatomy, plant culture, and DNA isolation. The results demonstrated a significant improvement in participants’ abilities to operate basic biotechnology tools, understand applied biotechnology concepts, and develop innovative practicum activities aligned with the Merdeka Curriculum. In addition, this activity strengthened collaboration among schools, universities, and media in disseminating science learning innovations. In conclusion, the implementation of technology-based biology practicum is effective in improving participants’ competencies and scientific literacy and has strong potential for sustainable development through continued mentoring and the development of digital modules.
Integrated Black Soldier Fly Bioconversion and Biodrying for Community-Based Organic Waste Management: A Circular Economy Model in Kota Padang, Indonesia Robby Jannatan; Resti Rahayu; Fadjar Goembira; Silvi Yuliani; Intan Cahaya Ramadhani; Yona Afriani
Warta Pengabdian Andalas Vol 33 No 2 (2026)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.33.2.156-165.2026

Abstract

Padang City produces over 660 tons of waste each day, and more than 60% of it is organic. Most of this ends up at the Air Dingin landfill, which has long exceeded its capacity and still operates through open dumping. While Black Soldier Fly (BSF; Hermetia illucens) larvae have attracted growing research attention as an organic waste processor, studies combining BSF bioconversion with biodrying (TOSS) and digital market development within a single community-scale program are scarce. This study reports the implementation and evaluation of such an integrated program, carried out with the Smarkgood Farmer Group in Kota Padang. Working through a participatory action framework, the team executed five sequential stages: partner identification, knowledge dissemination, technical training, technology application, and field mentoring. Key interventions included constructing BSF biopond units, providing a waste shredder calibrated to optimal larval substrate size, introducing the TOSS biodrying method for residual organic material, building a waste supply partnership with the Padang BSF Maggot Association (Agodang), and guiding the group through e-commerce onboarding. Following these interventions, the group operated a more functional and productive facility, maintained a stable organic waste supply, and actively sold products through online platforms. This program illustrates how science-based bioconversion technology, waste valorization, and digital market access can be combined into a community model that is practically transferable to other urban settings facing similar waste pressures.