Claim Missing Document
Check
Articles

Found 13 Documents
Search

Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review Firmansyah, Tio; Saraswati, Utami; Ilham, Kurniadi; Jannatan, Robby; maliza, rita
Bioeksperimen: Jurnal Penelitian Biologi Vol 10, No 1: March 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v10i1.23534

Abstract

The continuous cell line known as T47D cells originates from the isolation of epithelial cells from the ductal breast tissue of a 54-year-old woman with metastatic breast cancer. Numerous plant species have been employed in alternative anti-breast cancer therapy, showing advancements in recent years. The aim of this systematic review is to assess the potential bioactive compounds from herbal plant extracts and analyze the effects of herbal plants on T47D breast cancer cells. This research employs a systematic approach to gather articles, encompassing related research questions, chosen databases, keyword selection, inclusion and exclusion criteria, as well as outcomes and conclusions regarding the collected articles. From the reviewed articles, several plants exhibit anti-breast cancer activity on T47D cell lines, namely Calamintha incana, Sterculia quadrifida, Psidium guajava, Uncaria nervosa, Syzygium aqueum, Capsicum annum, Bauhinia scandens, Lansium domesticum, and Garcinia cowa due to their content of bioactive compounds such as triterpenoids, alkaloids, phenolics, flavonoids, saponins, and tannins. These bioactive compounds from the plants exert significant influence on cell cycle, proliferation, fatty acid synthesis, and apoptosis of cancer cells.
EDUKASI DAN PEMBERDAYAAN KELOMPOK TANI SAWIT KABUPATEN DHARMASRAYA MELALUI PEMANFAATAN KUMBANG ELAEIDOBIUS KAMERUNICUS UNTUK MENINGKATKAN PRODUKTIVITAS DAN KESEJAHTERAAN MASYARAKAT Martinsyah, Rachmad Hersi; Ramadhan, Nugraha; Obel, Obel; Rezki, Dewi; Suhendra, Dede; Jannatan, Robby; Ronaldi, Ronaldi; Siswandra, Diko Okta; Diansyah, Rohan
Jurnal Abdi Insani Vol 12 No 11 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i11.3286

Abstract

This community service activity aimed to enhance the knowledge, skills, and awareness of oil palm farmers regarding the crucial role of the pollinating weevil Elaeidobius kamerunicus in supporting the natural and sustainable increase of oil palm fruit productivity. Currently, the low productivity of smallholder oil palm farms is generally caused by suboptimal pollination processes, a lack of farmer understanding of the biology and life cycle of pollinating insects, and the limited application of environmentally friendly technologies. The implementation methods of this service included counseling, interactive discussions, and field demonstrations on the identification, conservation, and utilization strategies of E. kamerunicus in oil palm plantations. The activity results showed an increase in farmer knowledge by 76.92% (based on pre-test and post-test), improved farmer skills in recognizing and preserving the habitat of the pollinating weevil, and the growth of collective awareness to reduce the use of pesticides that potentially harm pollinator insect populations. The long-term impact of this program is expected to increase oil palm fruit productivity, strengthen the economic resilience of farmers, and support the realization of more environmentally friendly and sustainable oil palm cultivation practices. Thus, this education and empowerment activity makes a real contribution to improving the welfare of oil palm farming communities while preserving the plantation agroecosystem.  
Enhanced Oviposition Preferences and Larval Performance of Hermetia illucens L. in Fruit Wastes Fermented by Effective Microorganisms Rahayu, Resti; Jannatan, Robby; Ronaldo, Muhamad; Muslima, Risa Ukhti
Makara Journal of Science Vol. 29, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Organic waste comprises a considerable portion of global waste, requiring effective management. The ability of the black soldier fly (Hermetia illucens, BSF) to convert organic waste into biomass has been well reported. However, bioconversion can be hindered by fiber-rich substrates, a challenge that can be addressed through substrate pretreatment. This study examined the oviposition preferences and larval performance of BSFs in several fruit wastes fermented by effective microorganisms (EMs), which were compared to non-fermented substrates. The oviposition attractants utilized pineapple peel and overripe soursop, with larval performance evaluated among different treatments, i.e., non-fermented pineapple peel (NFP), fermented pineapple peel (FP), non-fermented pineapple peel plus coconut endosperm waste (NFPC), and fermented pineapple peel plus coconut endosperm waste (FPC). Measured parameters included larval biomass, substrate consumption, the waste reduction index (WRI), and adult emergence. The result indicated that fermented pineapple peel produced the highest number of eggs among the oviposition attractant treatments. Larval biomass was highest in FP, while substrate consumption, WRI, and adult emergence rates were comparable between FP and FPC. Overall, the fermented substrates outperformed the non-fermented substrates across all parameters. These findings confirmed that fermentation with EMs enhances the utilization of fruit waste as an oviposition attractant and improves the performance of BSF bioconversion.