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All Journal Media Kesehatan Masyarakat Indonesia Jurnal Kesehatan Andalas Damianus Journal of Medicine Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Ilmu Kesehatan Masyarakat (The Public Health Science Journal) Jurnal Ilmu Kesehatan Masyarakat (The Public Health Science Journal)
Komang Ardi Wahyuningsih
Departemen Histologi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Katolik Indonesia Atma Jaya, Jakarta.
Humanities Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Perbandingan Perubahan Luas Luka dan Angiogenesis pada Jaringan Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Platelet Rich Fibrin dan Advanced Platelet Rich Fibrin Shantika Aqilla Kurnia; Komang Ardi Wahyuningsih
Jurnal Kesehatan Andalas Vol 10, No 1 (2021): Online March 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i1.1464

Abstract

Burns increase tissue damage by free radicals, thus hindering the healing process. Platelet Rich Fibrin (PRF) and Advanced Platelet Rich Fibrin (A-PRF) are autologous fibrin matrices that contain growth factors and have been proven to increase tissue formation and regeneration. Objectives: To determined the effect of applying PRF and A-PRF on deep second-degree burns. Methods: This study was experimental research on twenty male Sprague Dawley rats were randomly divided into four groups. Group A and B as control groups received NaCl 0,9% and silver sulfadiazine ointment, respectively. Group C was given PRF and group D was given A-PRF. Burns are photographed and the area was calculated using the ImageJ application. After 14 days of therapy, the burn areas were excised and made into histological slides. Microscopic study of angiogenesis was observed using a microscope at 400x magnification. Results: Changes in wound surface area in PRF and A-PRF groups were 3,106 cm and 2,333 cm. The number of angiogenesis in PRF and A-PRF groups were 3.88 and 5.88. The data was analyzed using One-Way Anova and the results showed that there were no significant differences between the changes in the wound area and angiogenesis of PRF and A-PRF groups. Conclusion: This study showed that there are no significant differences in changes in wound surface area and angiogenesis of burn injury after topical application of PRF and A-PRF.Keywords:  angiogenesis, burn injury, changes in wound surface area, A-PRF, PRF
The Correlation between Vitamin D Intake and Quality of Life in the 17-35 Age Group Suci Prasetyo; Veronika Maria Sidharta; Komang Ardi Wahyuningsih; Yunisa Astiarani; In Sil Huh
Media Kesehatan Masyarakat Indonesia Vol. 18 No. 3: SEPTEMBER 2022
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30597/mkmi.v18i3.20932

Abstract

Vitamin D testing increased significantly during the Coronavirus Disease-19 (COVID-19) pandemics due to its role in regulating the immune system. Therefore, vitamin D deficiency is associated with susceptibility to various diseases that may affect the quality of life regarding physical health, psychological well-being, social and environmental aspects. The study aimed to determine whether there is an association between vitamin D intake and quality of life in the 17 to 35-year-old age group. A cross-sectional study was conducted from April to November 2021. The sample consisted of students from the School of Medicine and Health Sciences Atma Jaya Catholic University of Indonesia, and their relatives in the same age group, who were selected using a consecutive sampling. Vitamin D intake was measured using Vitamin D Estimation Only - Food Frequency Questionnaire (VIDEO-FFQ). At the same time, the quality of life was assessed using the World Health Organization Quality of Life (WHOQOL)-BREF questionnaire. Data analysis was performed using the Chi-square test. Of the 127 respondents, the results showed that most of respondents had inadequate vitamin D intake and good quality of life (68.50%;59.10%). The highest mean of the four quality of life domains belongs to the environmental domain (3.94) with a standard deviation (SD) of ± 0.83. Data analysis showed no significant correlation between vitamin D intake and quality of life (p>0.05). The conclusion shows that there was no correlation between vitamin D intake and quality of life in the 17–35-year age group.
Hubungan Asupan Vitamin D dan Keluhan Muskuloskeletal pada Kelompok Usia 17-35 Tahun Florent Hasthiono; Komang Ardi Wahyuningsih; Veronika Maria Sidharta; Nawanto Agung Prastowo
Jurnal Ilmu Kesehatan Masyarakat Vol 12 No 02 (2023): Jurnal Ilmu Kesehatan Masyarakat
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikm.v12i02.1676

Abstract

Defisiensi vitamin D masih menjadi masalah kesehatan global sampai saat ini, tidak terkecuali negara tropis yang memiliki lebih banyak paparan sinar matahari. Studi di negara-negara Eropa, Amerika dan Asia menunjukkan tingkat defisiensi vitamin D berkisar antara 45-90%. Indonesia termasuk negara dengan tingkat defisiensi vitamin D yang tinggi, tetapi laporan mengenai status vitamin D dan upaya pencegahannya belum banyak dilakukan. Keluhan pada muskuloskeletal akan menimbulkan gangguan atau sensasi ketidaknyamanan, memengaruhi performa dalam bekerja dan mengurangi produktivitas terutama pada kelompok usia dewasa. Penelitian ini bertujuan untuk mengetahui hubungan antara asupan vitamin D dan keluhan muskuloskeletal pada kelompok usia 17-35 tahun pada mahasuswa Fakultas Kedokteran dan Ilmu Kesehatan (FKIK) Unika Atma Jaya dan kerabatnya pada rentang usia tersebut. Desain penelitian observasional analitik dengan pendekatan potong lintang. Pengambilan data dilakukan dengan metode consecutive sampling pada tahun 2021 di Indonesia. Asupan vitamin D diukur dengan Vitamin D Estimation Only - Food Frequency Questionnaire dan keluhan muskuloskeletal diukur dengan kuesioner Nordic Body Map. Data dianalisis dengan menggunakan uji Chi-square. Subjek penelitian sebanyak 108 responden. Hasil penelitian menunjukkan terdapat 67,6% responden dengan asupan vitamin D yang tidak adekuat dan 80,6% yang memiliki keluhan muskuloskeletal. Tidak terdapat hubungan yang signifikan antara asupan vitamin D dengan keluhan muskuloskeletal pada kelompok usia 17-35 tahun (P-value= 0,379).
Perbandingan obesitas general dan obesitas sentral terhadap risiko hipertensi pada usia dewasa di wilayah Kecamatan Cisauk Kabupaten Tangerang Komang Ardi Wahyuningsih; Ardini Raksanagara; Yuni Susanti; Nita Arisanti; Siska Wiramihardja; Elsa Pudji Setiawati
Bahasa Indonesia Vol 21 No 3 (2022): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v21i3.3927

Abstract

Pendahuluan: Hipertensi dan obesitas menjadi masalah kesehatan utama hampir diseluruh dunia saat ini. Kejadian hipertensi maupun obesitas meningkat dalam beberapa tahun terakhir. Obesitas telah diketahui sebagai faktor risiko utama terjadinya hipertensi. Penelitian ini bertujuan untuk membandingkan risiko obesitas general dengan menggunakan parameter indeks massa tubuh (IMT) dengan obesitas sentral yang menggunakan parameter rasio lingkar pinggang tinggi badan terhadap kejadian hipertensi pada subjek dewasa usia 26-45 tahun di Wilayah Kecamatan Cisauk Kabupaten Tangerang. Metode: Penelitian ini adalah penelitian potong lintang, pada subjek dewasa usia 26-45 tahun dengan obesitas general (IMT ≥ 25 kg/m2) dan obesitas sentral (rasio lingkar pinggang tinggi badan >0,5). Masing-   masing kelompok obesitas sebanyak 88 orang, diperoleh dengan menggunakan tehnik non probability sampling dengan metode consecutive sampling. Berat badan, tinggi badan, lingkar pinggang, dan tekanan darah diukur pada masing-masing responden. Indeks massa tubuh dan rasio lingkar pinggang tinggi badan dihitung. Analisis yang dipergunakan analisi univariat, bivariat dengan independent t-test, kemudian dilanjutkan dengan analisis multivariate regresi logistik.  Hasil: Responden berusia dewasa awal (26-35 tahun) yang mengalami hipertensi sebanyak 26 orang (14,8%) sedangkan yang berusia dewasa akhir (36-45 tahun) sebanyak 63 orang (35,8%). Responden laki-laki yang mengalami hipertensi sebanyak 24 orang (13,6%) dan perempuan sebanyak 120 (36,9%). Responden dengan riwayat keluarga hipertensi dan saat ini mengalami hipertensi didapatkan sebanyak 52 orang (29,5%) dan tanpa riwayat keluarga hipertensi sebanyak 37 orang (21,0%). Responden dengan riwayat keluarga hipertensi dan saat ini mengalami hipertensi adalah 52 (29,5%) dan 37 (21,0%) tanpa riwayat keluarga hipertensi. Responden dengan riwayat keluarga hipertensi memiliki risiko hipertensi 2,7 kali (OR (CI 95%) =2,670 (1,450 – 4,919)) jika dibandingkan dengan responden yang tidak memiliki riwayat hipertensi dalam keluarga.  Responden dengan obesitas general secara signifikan meningkatkan risiko hipertensi 0.5 kali (OR (CI95%) = 0,457 (0,250 – 0,835), p=0,016) jika dibandingkan dengan responden tanpa obesitas general. Sedangkan responden dengan obesitas sentral memiliki risiko 0.5 kali (OR (CI 95%) = 0,489 (0,420 – 0,569), p=0,243). Simpulan: Hasil penelitian ini menunjukkan bahwa antara obesitas general obesitas sentral memiliki risiko yang sama terhadap hipertensi.  
Comparison Between Platelet-Rich Plasma Single- and Double-Spin Centrifugation to Treat Androgenetic Alopecia: A Systematic Review Stella Skolastika Suwana; Komang Ardi Wahyuningsih; Laurentius Aswin Pramono
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v7i10.13319

Abstract

There are no established guidelines for the management of androgenetic alopecia (AGA). A new therapy with promising results is Platelet-Rich Plasma (PRP). PRP has a variety of preparation methods, such as single spin and double spin centrifugation and still there is no consensus on the method of preparation. There is controversy of which preparation method is better. We searched PubMed, EBSCO, Clinical Key, ProQuest, Cochrane Library, Science Direct, Clinical Trial, Open Access, Wolters Kluwer, Google Scholar, GARUDA, and AtmaLib until Oct 2020 for human studies using PRP for AGA treatment. We assessed 3375 papers; 6 studies met the inclusion criteria and evaluated 128 AGA patients, 112 male and 16 female, 18-63 years old. Participants varied from type II-VI based on the Hamilton-Norwood classification system and degree 2 based on the Ludwig classification system. Four studies used the single-spin centrifugation PRP preparation method and two studies used the double-spin PRP preparation method. The studies stated the increases in growth factor levels. All studies showed PRP significantly affected hair growth in AGA patients. PRP has been shown to increase hair growth parameters in form of hair density (P <0.0001). PRP has been shown to increase hair density and hair count. Growth factors in PRP induce cell proliferation and tissue angiogenesis. The results of single-spin centrifugation preparation method provide a greater increase in hair density. But, data reports from the study did not allow comparisons to determine the best PRP preparation method for AGA treatment. Therefore further study is needed.
Hubungan Asupan Vitamin D dan Keluhan Muskuloskeletal pada Kelompok Usia 17-35 Tahun Florent Hasthiono; Komang Ardi Wahyuningsih; Veronika Maria Sidharta; Nawanto Agung Prastowo
Jurnal Ilmu Kesehatan Masyarakat Vol 12 No 02 (2023): Jurnal Ilmu Kesehatan Masyarakat
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikm.v12i02.1676

Abstract

Defisiensi vitamin D masih menjadi masalah kesehatan global sampai saat ini, tidak terkecuali negara tropis yang memiliki lebih banyak paparan sinar matahari. Studi di negara-negara Eropa, Amerika dan Asia menunjukkan tingkat defisiensi vitamin D berkisar antara 45-90%. Indonesia termasuk negara dengan tingkat defisiensi vitamin D yang tinggi, tetapi laporan mengenai status vitamin D dan upaya pencegahannya belum banyak dilakukan. Keluhan pada muskuloskeletal akan menimbulkan gangguan atau sensasi ketidaknyamanan, memengaruhi performa dalam bekerja dan mengurangi produktivitas terutama pada kelompok usia dewasa. Penelitian ini bertujuan untuk mengetahui hubungan antara asupan vitamin D dan keluhan muskuloskeletal pada kelompok usia 17-35 tahun pada mahasuswa Fakultas Kedokteran dan Ilmu Kesehatan (FKIK) Unika Atma Jaya dan kerabatnya pada rentang usia tersebut. Desain penelitian observasional analitik dengan pendekatan potong lintang. Pengambilan data dilakukan dengan metode consecutive sampling pada tahun 2021 di Indonesia. Asupan vitamin D diukur dengan Vitamin D Estimation Only - Food Frequency Questionnaire dan keluhan muskuloskeletal diukur dengan kuesioner Nordic Body Map. Data dianalisis dengan menggunakan uji Chi-square. Subjek penelitian sebanyak 108 responden. Hasil penelitian menunjukkan terdapat 67,6% responden dengan asupan vitamin D yang tidak adekuat dan 80,6% yang memiliki keluhan muskuloskeletal. Tidak terdapat hubungan yang signifikan antara asupan vitamin D dengan keluhan muskuloskeletal pada kelompok usia 17-35 tahun (P-value= 0,379).
Perbandingan Perubahan Luas Luka dan Angiogenesis pada Jaringan Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Platelet Rich Fibrin dan Advanced Platelet Rich Fibrin Kurnia, Shantika Aqilla; Wahyuningsih, Komang Ardi
Jurnal Kesehatan Andalas Vol. 10 No. 1 (2021): Online March 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i1.1464

Abstract

Burns increase tissue damage by free radicals, thus hindering the healing process. Platelet Rich Fibrin (PRF) and Advanced Platelet Rich Fibrin (A-PRF) are autologous fibrin matrices that contain growth factors and have been proven to increase tissue formation and regeneration. Objectives: To determined the effect of applying PRF and A-PRF on deep second-degree burns. Methods: This study was experimental research on twenty male Sprague Dawley rats were randomly divided into four groups. Group A and B as control groups received NaCl 0,9% and silver sulfadiazine ointment, respectively. Group C was given PRF and group D was given A-PRF. Burns are photographed and the area was calculated using the ImageJ application. After 14 days of therapy, the burn areas were excised and made into histological slides. Microscopic study of angiogenesis was observed using a microscope at 400x magnification. Results: Changes in wound surface area in PRF and A-PRF groups were 3,106 cm and 2,333 cm. The number of angiogenesis in PRF and A-PRF groups were 3.88 and 5.88. The data was analyzed using One-Way Anova and the results showed that there were no significant differences between the changes in the wound area and angiogenesis of PRF and A-PRF groups. Conclusion: This study showed that there are no significant differences in changes in wound surface area and angiogenesis of burn injury after topical application of PRF and A-PRF.Keywords:  angiogenesis, burn injury, changes in wound surface area, A-PRF, PRF
Perbandingan Perubahan Luas Luka dan Angiogenesis pada Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Advanced Platelet-rich Fibrin dan Advanced Platelet-rich Fibrin Plus Stella, Ellia; Wahyuningsih, Komang Ardi
Jurnal Kesehatan Andalas Vol. 10 No. 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i2.1616

Abstract

Platelet-rich fibrin (PRF) has a lot of benefits in the process of healing. The new generation of PRF, namely advanced PRF plus (A-PRF+), has a different fibrin structure and more growth factors compared to Advanced PRF (A-PRF), the generation before A-PRF+. Objectives:To compared the effects of A-PRF and A-PRF+ on the IIB degree burn. Methods: This experimental study used 20 male Sprague Dawley rats. All rats were given IIB degree burn and divided into four groups. Group 1 was treated with saline, Group 2 was treated with silver sulfadiazine 1%, Group 3 was treated with A-PRF, and Group 4 was treated with A-PRF+. Wound size reduction will be calculated every two days and measured with ImageJ and the wound would be made into a histological slide on day 14 to calculate angiogenesis. Results: Changes in the wound surface area for the group that was given A-PRF dan A-PRF+ are 2,333cm and 4,827cm. The wound surface area’s data were analyzed using Kruskal-Wallis and the results are statistically not significant (p>0,05). The number of angiogenesis for the group that was give A-PRF and A-PRF+ as followed are 5,88 and 4,867. The angiogenesis data were analyzed using one-way ANOVA and the results are statistically not significant (p>0,05). Conclusion: There is no difference between the effect of A-PRF and A-PRF+ towards changes in wound surface area and angiogenesis in IIB degrees burn wounds.Keywords:  A-PRF, A-PRF+, burn wound, angiogenesis, wound surface area
Co-Authors Ardini Raksanagara Elsa Pudji Setiawati Florent Hasthiono In Sil Huh Kurnia, Shantika Aqilla Laurentius Aswin Pramono Nawanto Agung Prastowo Nita Arisanti Shantika Aqilla Kurnia Siska Wiramihardja Stella Skolastika Suwana Stella, Ellia Suci Prasetyo Veronika Maria Sidharta Yuni Susanti Yunisa Astiarani