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IDENTIFIKASI SENYAWA ANTIFUNGI DARI KULIT BATANG KECAPI (Sandoricum koetjape) DAN AKTIVITASNYA TERHADAP Candida albicans Warsinah, Warsinah; Kusumawati, Eka; Sunarto, Sunarto
Majalah Obat Tradisional Vol 16, No 3 (2011)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (933.563 KB) | DOI: 10.14499/mot-TradMedJ16iss3pp%p

Abstract

Kecapi (Sandoricum koetjape (Burm.f.) Merr) merupakan salah satu tanaman obat tradisional dari famili Meliaceae, mengandung senyawa flavonoid, saponin dan polifenol yang dapat digunakan sebagai antifungi. Penelitian ini bertujuan untuk mengetahui senyawa dalam kulit batang S. koetjape yang bersifat antifungi terhadap C. albicans. Penelitian dilakukan dengan dua tahap yaitu ekstraksi dengan metode maserasi menggunakan pelarut metanol dan fraksinasi dengan metode kromatografi kolom menggunakan pelarut n-heksan,kloroform, etil asetat dan metanol. Selanjutnya dilakukan uji aktivitas terhadap C. albicans dan identifikasi fraksi aktif dengan Gas Chromatograpy-Mass Spectrometry (GC-MS). Hasil penelitian menunjukkan bahwa ekstrak metanol kulit batang S. koetjape memiliki aktivitas antifungi terhadap C. albicans sebesar 39,65% b/v. Ekstrak metanol di fraksinasi berdasarkan gradient polaritasmenghasilkan6 fraksi dengan aktivitas antifungi terbesar yaitu fraksi III (43,02%b/v), diikuti dengan fraksi V (39,66%b/v), fraksi IV (39,02%b/v), fraksi II (37,91%b/v), fraksi VI (35,49%b/v) dan fraksi I (33,72%b/v). Identifikasi senyawa dengan GC-MS dilakukan pada fraksi III, dan diperoleh senyawa yang berpotensi sebagai antifungi adalah α-gurjunene, trans-caryophyllene, aromadendrene, α-humulene, β-caryophyllene,δ-cadinene, alloaromadendren, octadecanoic acid (as. stearat), hexadecanoic acid metil ester (metil palmitat), hexadecanoic acid (as. palmitate), 9-octadecenoic acid metil ester (metil elaidate), 9-octadecenoic acid (as. oleat) 
Spodoptera frugiperda: Hama utama pada tanaman jagung dan strategi pengendaliannya Anintyas, Dytri; Safitri, Khofifah Nur Indah; Kusumawati, Eka; Masoyogie, Kholfira; Dirmawati, Suskandini Ratih; Aeny, Titik Nur; Suharjo, Radix
Jurnal Proteksi Agrikultura Vol. 1 No. 2 (2024): NOVEMBER, JURNAL PROTEKSI AGRIKULTURA
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpa.2166-80

Abstract

Spodoptera frugiperda (FAW), or fall armyworm, is a major invasive pest that attacks corn crops in various tropical and subtropical regions. In recent decades, the global spread of FAW has been accelerated by international trade and climate change. In Indonesia, the presence of this pest was first reported in 2019 in West Sumatra, with attacks spreading to various other areas. The FAW life cycle includes four stages (eggs, larvae, pupae, and imago) with significant levels of plant damage, especially in the larval stage.Various con- trol strategies have been implemented, including integrated pest management (IPM) approaches, such as the use of biological agents (Beauveria bassiana and Metarhizium anisopliae), push-pull techniques, and crop rotation. In addition, the development of pest-resistant corn varieties is an important alternative. Recent re- search has identified two genetic lines of FAW, namely corn and rice lines, which show differences in host preference and resistance to insecticides.This study highlights the need for further development of ecologi- cally based strategies, including exploration of local parasitoids and effective bioinsecticide formulations. In addition, genetic and microbiota analyses offer new potential in understanding FAW population dynamics and its control. These results are expected to be the basis for sustainable pest management in Indonesia and other regions.
Analysis of the Relation Between Learning Environment and Economic Condition on Learning Achievement Hanafi, Imam; Dharmawan, Donny; Kusumawati, Eka; Letasado, Muhamad Rusadi; Abdurohim, Abdurohim
Edumaspul: Jurnal Pendidikan Vol 7 No 2 (2023): Edumaspul: Jurnal Pendidikan
Publisher : Universitas Muhammadiyah Enrekang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33487/edumaspul.v7i2.7255

Abstract

The purpose of this research is to analyze the relationship between learning environment and economic condition on learning achievement. This research uses quantitative methods. Population used in this research are Medan City Private University students. Based on determining the target sample, sample in the research are 50 students from Medan City Private University. Data analysis in this study used a correlation test. The research results show that there is a relationship between learning environment and learning achievement in Medan City Private University students. There is a relationship between economic condition and learning achievement in Medan City Private University students.
Mathematical Model of COVID-19 with the Influence of Vaccination Purnami, Ndaru Atmi; Prawadika, Luqman Nuradi; Pasangka, Irvandi Gorby; Findasari, Findasari; Kusumawati, Eka; Pratama, Ilham Yoga; Suharis, Ridho; Maturbongs, Nadhira Hasna
Euler : Jurnal Ilmiah Matematika, Sains dan Teknologi Volume 13 Issue 3 December 2025
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The COVID-19 pandemic, which first emerged at the end of 2019, has had a significant impact on people's lives around the world. In Indonesia, the outbreak began to develop in February 2020. Although the pandemic has now passed and people have started to resume their normal activities, some individuals are still being infected with COVID-19, even though the number of cases is now under control. One of the key factors in controlling COVID-19 is vaccination. The extent to which vaccination affects COVID-19 transmission will be discussed in this study. Furthermore, a numerical simulation will be conducted on this mathematical model to observe the impact of vaccination on COVID-19. The mathematical model of COVID-19 with vaccination influence will describe the interaction between six population classes, namely: the class of susceptible individuals who can be infected (Susceptible – S), the class of exposed individuals (Exposed – E), the class of vaccinated individuals who have never been infected (Vaccinated – V), the class of infected individuals (Infected – I), the class of individuals who have recovered (Recovered – R), and the class of infected individuals who have died (Death – D). It is important to note that COVID-19 is a disease caused by infection with the coronavirus. A person who has not yet been infected with the virus has the potential to be exposed. One way to prevent exposure is through vaccination. In Indonesia, vaccination has been made mandatory three times: the first dose, the second dose, and the booster. However, because the coronavirus has an incubation period, there is no guarantee that a vaccinated person has not already been exposed to the virus. Exposed individuals will become infected with COVID-19 once the incubation period ends. Infected individuals may show symptoms or be asymptomatic. An infected individual has two possible outcomes: recovery or death. The modeling is based on the SEVIRD model, with its parameters estimated using data. This study produces a mathematical model of COVID-19 with vaccination influence, showing that vaccination plays a role in controlling the spread of COVID-19.