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All Journal BALI MEDICAL JOURNAL (BMJ) Jurnal Biologi Tropis Acta Biochimica Indonesiana Journal of Research in Social Science and Humanities
Teguh Dwi Nugroho, Teguh Dwi
Urology Division, Department of General Surgery in Sanglah General Hospital, the Major Teaching Hospital for Udayana University, Bali-Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Social Sciences Other

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CHARACTERISTICS OF HYPOSPADIAS CASES IN SANGLAH GENERAL HOSPITAL, BALI-INDONESIA: A DESCRIPTIVE STUDY Duarsa, Gede Wirya Kusuma; Nugroho, Teguh Dwi
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.128 KB)

Abstract

Background: Hypospadias is one of the most common congenital anomalies. The purpose of this study is to assess the characteristics of hypospadias patients in Sanglah General Hospital, and the type of hypospadias repair and the outcome. Methods: The data is collected retrospectively from the hypospadias patients’ medical records who undergone a hypospadias repair between January 2009 to April 2012. The data is analyzed descriptively to describe the characteristics of hypospadias patients, the procedures taken, and the outcomes. Results: From 42 patients, type of hypospadias are 33.3% (n=14) penoscrotal; 21.4% (n=9) scrotal; 14.3% (n=6) corona; 26.2% (n=11) penile; 2.4% (n=1) subcoronal; 2.4% (n=1) and perineal. Chordee was present in 67.9% cases (n=36), and cryptorchidism present in 3.7 % case (n=2). The urethroplasty techniques applied: TIP 55.6% (n=15); Duckett Preputial Island Flap 14.8% (n=4); MAGPI 14.8% (n=4); 14.8% (n=4) two stages urethroplasty. Complication rate of Duckett is 50% (n=2) urethra cutaneous fistula; MAGPI 25% (n=1) meatal stenosis; TIP 20% (n=3), 2 urethrocutaneous fistula, 1 urethral stricture; 2 stages urethroplasty 0% (n=0). Conclusion: The findings suggest a different frequency of the proportion of the type of hypospadias in this study when compare to the readily available literature. The age of the patients undergone hipospadias repair was higher compare to other studies. TIP technique was the most preferred in Sanglah Hospital.
Antibacterial activity of garlic ethanol extract (Allium sativum Linn) against Propionibacterium acnes Seran, Stefania Danita Dwi W. M.; Nurina, Rr. Listyawati; Hutasoit, Regina Marvina; Nugroho, Teguh Dwi
Acta Biochimica Indonesiana Vol. 8 No. 1 (2025): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.186

Abstract

Background: Acne vulgaris is a common dermatological condition largely associated with Propionibacterium acnes infection. The increasing resistance of P. acnes to conventional antibiotics necessitates alternative treatment approaches. Garlic (Allium sativum Linn) has documented antimicrobial properties, yet its specific activity against P. acnes remains underexplored. Objective: To evaluate the antibacterial activity of garlic extract at various concentrations against P. acnes and determine its potential as an alternative acne treatment. Methods: Garlic extract was prepared using ethanol maceration, followed by phytochemical screening. The antibacterial activity against P. acnes was assessed using the well diffusion method at concentrations of 10%, 40%, 70%, and 100%, with doxycycline and distilled water serving as positive and negative controls, respectively. Inhibition zones were measured and statistically analyzed. Results: Phytochemical screening revealed the presence of tannins, flavonoids, alkaloids, saponins, and triterpenoids in the garlic extract. All tested concentrations exhibited significant antibacterial activity against P. acnes. The inhibition zone diameters were 32.83 mm (100%), 28.90 mm (70%), 26.60 mm (40%), and 15.29 mm (10%), compared to 38.81 mm for doxycycline, with statistically significant differences between all groups (p<0.05). Conclusion: Garlic extract demonstrates potent antibacterial activity against P. acnes, with 70% concentration providing optimal efficacy relative to extract concentration, suggesting its potential as a natural alternative for acne treatment.
Knowledge as Dominant Protective Factor against Scabies Incidence in Sonraen, East Nusa Tenggara Wiranata, Nyoman Agung Ardi; Deo, Dwita Anastasia; Nugroho, Teguh Dwi; Handoyo, Nicholas Edwin
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.11043

Abstract

Scabies persists as a public health challenge in resource-limited rural areas. This study aimed to analyze the association between knowledge level and personal hygiene practices with scabies incidence and to identify the dominant factor in the working area of Sonraen Health Center. A case–control study was conducted on 66 subjects (33 cases and 33 controls) from June to July 2025. Cases were selected by total sampling from medical records, while controls were chosen via simple random sampling. Data were collected using structured questionnaires and clinical observation, analyzed with the Chi-Square test and binary logistic regression. The knowledge level showed a statistically significant relationship with scabies incidence (p = 0.012). Multivariate analysis showed that respondents who had good knowledge (p = 0.013; AOR = 5.65; 95% CI: 1.14 – 27.91) and personal hygiene were not significant in the final model (p = 0.164), although respondents with fairly good hygiene had an Odds Ratio value of 3.21 95% CI: 0.96 – 10.70 with a p value = 0.058. Knowledge acts as the dominant protective factor against scabies in Sonraen. Public health interventions should prioritize contextual health education on household-based scabies prevention.
The Effect of Bay Leaf (Syzygium polyanthum) Extract on The Hepatic Histopathology of Male White Rats (Rattus norvegicus) Induced by Ibuprofen Dirganingrum, Kadek Galuh; Damanik , Efrisca M. Br.; Nugroho, Teguh Dwi; Deo, Dwita Anastasia
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.11149

Abstract

Excessive use of ibuprofen can trigger Drug Induced Liver Injury (DILI) through oxidative stress mechanisms. Syzygium polyanthum (bay leaf) contains antioxidant compounds with potential hepatoprotective activity. Objective to determine the effect of ethanol extract of bay leaves on the improvement of liver histopathology in ibuprofen-induced rats. This experimental study used 36 Sprague Dawley rats divided into six groups: Negative Control, two Positive Controls (ibuprofen induction), and treatment groups P1, P2, and P3 (ibuprofen induction + extract at doses of 50, 150, and 250 mg/kgBW). Histopathological changes were evaluated using the Manja Roenigk scoring system. Data were analysed using the Kruskal–Wallis test followed by Dunn’s Post Hoc test. There were significant differences among groups (p < 0.001). Group P3 (250 mg/kgBW) showed the lowest damage score (1.35 ± 0.15), approaching normal conditions, and differed significantly from P1 (2.37 ± 0.27), which showed the highest damage. Lower doses did not provide optimal improvement. Bay leaf extract significantly improved liver histopathology in ibuprofen-induced rats in a dose-dependent manner, with the most effective dose being 250 mg/kgBW.
Relationship Between Duration of Hemodialysis and Knowledge Level About Chronic Kidney Disease Among Hemodialysis Patients in Kupang City Soemoeljo, Betty Griselda Christine; Nugroho, Teguh Dwi; Rante, Su Djie To; Setianingrum, Elisabeth Levina Sari
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11194

Abstract

Long-term kidney disease is a worldwide health issue that is becoming more common, leading to numerous individuals needing ongoing hemodialysis treatment. Understanding the illness and the management of hemodialysis is vital for successful treatment and improving life quality. However, the length of time a patient undergoes hemodialysis does not always match their level of understanding about the condition. The aim of this study was to determine the relationship between hemodialysis duration and knowledge levels about chronic kidney disease among hemodialysis patients in Kupang City. The research method used was analytical with a cross-sectional design. Sampling was conducted using purposive sampling according to specific inclusion criteria. Knowledge levels were assessed using the Chronic Kidney Disease Knowledge Questionnaire, while the duration of hemodialysis was gathered from medical records. The data analysis involved univariate and bivariate analysis, utilizing the Chi-square test (p < 0.05). A large portion of the participants were between the ages of 52 to 66 years (41.1%), had completed high school (35.6%), and were either unemployed or retired (36.2%). Regarding the length of hemodialysis, the majority of participants fell into the category of more than 24 months (43.6%). Knowledge levels ranged from good to poor. Bivariate analysis indicated no significant connection between the duration of hemodialysis and the understanding of chronic kidney disease (p-value = 0.500). There is no association between the length of hemodialysis and the understanding of chronic kidney disease among patients receiving hemodialysis in Kupang City.
Relationship between Menarche Age and the Incidence of Primary Dysmenorrhea in Christian Junior High School Students of Citra Bangsa Mandiri Kupang City Fallo, Giovani Maria; Ratu, Kristian; Wardani , Nimas Prita R. K.; Nugroho, Teguh Dwi
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11395

Abstract

Primary dysmenorrhea ranks among the most prevalent menstrual issues in teenagers, impacting their everyday life and general well-being. The age at which menstruation begins has frequently been linked to the likelihood of experiencing dysmenorrhea; however, previous studies have produced mixed results. The goal of this research was to examine the connection between the age of menarche and the incidence of primary dysmenorrhea in female students at Kristen Citra Bangsa Mandiri Junior High School in Kupang. This investigation utilized an analytical observational method with a cross-sectional approach. A total of 54 students were chosen using purposive sampling according to specific inclusion and exclusion standards. Menarche age was classified as early (younger than 12 years), normal (12 to 14 years), and late (older than 14 years). The WaLIDD Score was employed to evaluate primary dysmenorrhea. The data were processed using the chi-square test, with a significance threshold set at p<0.05. The findings indicated that 55.6% of female students had a normal age for the start of menstruation, while 44.4% started early. The occurrence of primary dysmenorrhea was found to be 77.8%, with mild cases at 38.9%, moderate cases at 31.5%, and severe cases at 7.4%. Those who did not experience primary dysmenorrhea made up 22.2% of the respondents. The statistical analysis yielded a p=0.90 value. There was no significant link between the age of menarche and the prevalence of primary dysmenorrhea among students at Citra Bangsa Mandiri Christian Junior High School in Kupang City.
The Relationship Between Hemodialysis Frequency and the Tendency of Depressive Symptoms Among Dialysis Patients Maheswari, Jessica Maria Karminda; Nugroho, Teguh Dwi; Tunggal, Deif; Damanik, Efrisca Meliyuita Br
Journal of Research in Social Science and Humanities Vol 5, No 4 (2025)
Publisher : Utan Kayu Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/jrssh.v5i4.482

Abstract

Background: Patients undergoing hemodialysis often experience both physical and psychological impacts. This study aimed to determine the relationship between hemodialysis frequency and the tendency of depressive symptoms. Methods: This was a cross-sectional study conducted at three hospitals in Kupang City: Siloam Hospital Kupang, Prof. W.Z. Yohanes Regional Hospital, and dr. Ben Mboi Central Hospital. Research variables included hemodialysis frequency and the tendency of depressive symptoms. Data were collected using the BDI-II questionnaire through interviews or self-administration. Statistical analysis was performed using Spearman’s correlation with a 95% confidence level. Results: Among 163 respondents, 5 (3.1%) had a low frequency, 140 (85.9%) had a moderate frequency, and 18 (11%) had a high frequency. A total of 101 patients (62%) were categorized as normal, 28 (17.5%) had mild depression, 22 (13.5%) moderate depression, and 12 (7.4%) severe depression. Statistical analysis revealed no significant relationship between hemodialysis frequency and depressive symptom tendency (p = 0.491 0.05). Conclusion: Although many hemodialysis patients experienced depressive symptoms, statistical analysis did not show a significant association between hemodialysis frequency and the tendency of depressive symptoms. Further studies are needed to explore other factors influencing depression in this population.
Co-Authors Damanik , Efrisca M. Br. Damanik, Efrisca Meliyuita Br Dirganingrum, Kadek Galuh Dwita Anastasia Deo Fallo, Giovani Maria Gede Wirya Kusuma Duarsa Hutasoit, Regina Marvina Maheswari, Jessica Maria Karminda Nicholas Edwin Handoyo Nurina, Rr. Listyawati Rante, Su Djie To Ratu, Kristian Seran, Stefania Danita Dwi W. M. Setianingrum, Elisabeth Levina Sari Soemoeljo, Betty Griselda Christine Tunggal, Deif Wardani , Nimas Prita R. K. Wiranata, Nyoman Agung Ardi