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All Journal BALI MEDICAL JOURNAL (BMJ) Jurnal Biologi Tropis
Teguh Dwi Nugroho, Teguh Dwi
Urology Division, Department of General Surgery in Sanglah General Hospital, the Major Teaching Hospital for Udayana University, Bali-Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology

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CHARACTERISTICS OF HYPOSPADIAS CASES IN SANGLAH GENERAL HOSPITAL, BALI-INDONESIA: A DESCRIPTIVE STUDY Duarsa, Gede Wirya Kusuma; Nugroho, Teguh Dwi
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.128 KB)

Abstract

Background: Hypospadias is one of the most common congenital anomalies. The purpose of this study is to assess the characteristics of hypospadias patients in Sanglah General Hospital, and the type of hypospadias repair and the outcome. Methods: The data is collected retrospectively from the hypospadias patients’ medical records who undergone a hypospadias repair between January 2009 to April 2012. The data is analyzed descriptively to describe the characteristics of hypospadias patients, the procedures taken, and the outcomes. Results: From 42 patients, type of hypospadias are 33.3% (n=14) penoscrotal; 21.4% (n=9) scrotal; 14.3% (n=6) corona; 26.2% (n=11) penile; 2.4% (n=1) subcoronal; 2.4% (n=1) and perineal. Chordee was present in 67.9% cases (n=36), and cryptorchidism present in 3.7 % case (n=2). The urethroplasty techniques applied: TIP 55.6% (n=15); Duckett Preputial Island Flap 14.8% (n=4); MAGPI 14.8% (n=4); 14.8% (n=4) two stages urethroplasty. Complication rate of Duckett is 50% (n=2) urethra cutaneous fistula; MAGPI 25% (n=1) meatal stenosis; TIP 20% (n=3), 2 urethrocutaneous fistula, 1 urethral stricture; 2 stages urethroplasty 0% (n=0). Conclusion: The findings suggest a different frequency of the proportion of the type of hypospadias in this study when compare to the readily available literature. The age of the patients undergone hipospadias repair was higher compare to other studies. TIP technique was the most preferred in Sanglah Hospital.
Knowledge as Dominant Protective Factor against Scabies Incidence in Sonraen, East Nusa Tenggara Wiranata, Nyoman Agung Ardi; Deo, Dwita Anastasia; Nugroho, Teguh Dwi; Handoyo, Nicholas Edwin
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.11043

Abstract

Scabies persists as a public health challenge in resource-limited rural areas. This study aimed to analyze the association between knowledge level and personal hygiene practices with scabies incidence and to identify the dominant factor in the working area of Sonraen Health Center. A case–control study was conducted on 66 subjects (33 cases and 33 controls) from June to July 2025. Cases were selected by total sampling from medical records, while controls were chosen via simple random sampling. Data were collected using structured questionnaires and clinical observation, analyzed with the Chi-Square test and binary logistic regression. The knowledge level showed a statistically significant relationship with scabies incidence (p = 0.012). Multivariate analysis showed that respondents who had good knowledge (p = 0.013; AOR = 5.65; 95% CI: 1.14 – 27.91) and personal hygiene were not significant in the final model (p = 0.164), although respondents with fairly good hygiene had an Odds Ratio value of 3.21 95% CI: 0.96 – 10.70 with a p value = 0.058. Knowledge acts as the dominant protective factor against scabies in Sonraen. Public health interventions should prioritize contextual health education on household-based scabies prevention.
The Effect of Bay Leaf (Syzygium polyanthum) Extract on The Hepatic Histopathology of Male White Rats (Rattus norvegicus) Induced by Ibuprofen Dirganingrum, Kadek Galuh; Damanik , Efrisca M. Br.; Nugroho, Teguh Dwi; Deo, Dwita Anastasia
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.11149

Abstract

Excessive use of ibuprofen can trigger Drug Induced Liver Injury (DILI) through oxidative stress mechanisms. Syzygium polyanthum (bay leaf) contains antioxidant compounds with potential hepatoprotective activity. Objective to determine the effect of ethanol extract of bay leaves on the improvement of liver histopathology in ibuprofen-induced rats. This experimental study used 36 Sprague Dawley rats divided into six groups: Negative Control, two Positive Controls (ibuprofen induction), and treatment groups P1, P2, and P3 (ibuprofen induction + extract at doses of 50, 150, and 250 mg/kgBW). Histopathological changes were evaluated using the Manja Roenigk scoring system. Data were analysed using the Kruskal–Wallis test followed by Dunn’s Post Hoc test. There were significant differences among groups (p < 0.001). Group P3 (250 mg/kgBW) showed the lowest damage score (1.35 ± 0.15), approaching normal conditions, and differed significantly from P1 (2.37 ± 0.27), which showed the highest damage. Lower doses did not provide optimal improvement. Bay leaf extract significantly improved liver histopathology in ibuprofen-induced rats in a dose-dependent manner, with the most effective dose being 250 mg/kgBW.
Co-Authors Damanik , Efrisca M. Br. Dirganingrum, Kadek Galuh Dwita Anastasia Deo Gede Wirya Kusuma Duarsa Nicholas Edwin Handoyo Wiranata, Nyoman Agung Ardi