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Helminth Infection in Pregnancy: Effect on Serum Albumin Level and Pregnancy outcome Ridwan, Steven; Wahyuni, Sitti; Chalid, Maisuri T
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To determine the prevalence of helminth infection in pregnant women and its effect on albumin levels and pregnancy outcome. Method: A prospective cohort study was conducted on third trimester pregnant women presenting for antenatal care in several hospitals in Makassar. Information on subject demography was recorded using short questionnaire. Stool samples were collected to determine the presence of helminth infection. Albumin levels were measured from maternal blood and cord‐blood. Outcome of pregnancy was assessed upon delivery. Result: The prevalence of helminth infection in our subjects was 22.8%. Among 21 infected women, 17 were infected with Ascaris lumbricoides (80.9%), one with Trichuris trichiura and three with both Ascaris and Trichuris. The mean Ascaris lumbricoides intensity was 1769.3 epg (Range = 24‐11.688 epg). Helminth infections have no effect on either maternal or neonatal albumin levels (p=0.748 and p=0.480, respectively). Although it was not found to be significant (p>0.05), helminth infection seems to affect gestational age (OR 2.06, 95% CI 1.48‐2.86) and birth weight (OR 2.18, 95% CI 1.52‐3.14). Neonatal albumin level and pregnancy outcome were not affected by maternal albumin level. Conclusion: Helminth infection seems to affect pregnancy outcome in pregnant women in Makassar, but not through influence of albumin. Factors other than albumin level may responsible for such condition.

Lidocaine Prilocaine Cream versus LidocaineHCL Injection for Pain Relief during Second Degree of Perineal Tear Suturing after Vaginal Delivery: A Comparative Study Rahmawati, Rahmawati; Lotisna, David; Abdullah, Nusratuddin; Chalid, Maisuri T; Tessy, Telly
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Abstract Objective : To compare the effectiveness of topically applied lidocaine-prilocaine cream with lidocaine-HCl injection in the reduction of pain during second degree of perineal tear suturing after vaginal delivery. Methods : One hundred and twenty-four of women with second degree of perineal tear after vaginal delivery were enrolled in this randomized clinical trial. Women were assigned randomly to have either application of lidocaine-prilocaine cream (n=62) or local injection of lidocaine-HCl (n=62) for anesthetic during perineal suturing. Pain measured with viasual analog scale (VAS) for the first 5 minutes during the perineal suturing. Statistical analysis was performed by comparative analytic numerical unpaired with independent t test between the two groups and significance was assessed at p<0.05. Data were presented as mean ± standard deviation (SD). Results : There was no significantly different of pain score between lidocaine-prilocaine cream and lidocaine-HCl injection group (5.66±1.07 vs 5.56±1.5; p=0.473). Conclusion : Application of lidocaine-prolicaine cream as effective as injection of lidocaine for reducing pain during second degree of perineal tear suturing after vaginal delivery. Keywords : Lidocaine-prilocaine cream, lidocaine-HCl injection, pain, perineal suturing, vaginal delivery     Abstrak Tujuan: Untuk membandingkan efektivitas antara lidokain-prilokain topikal dan lidokain-HCl injeksi dalam mengurangi nyeri selama penjahitan luka perineum tingkat dua setelah persalinan normal. Metode: Seratus dua puluh empat perempuan dengan robekan perineum tingkat dua postpartum pervaginam mengikuti uji coba klinis secara acak ini. Enam puluh dua perempuan (n=62) menggunakan lidokain-prilokain topikal dan 62 perempuan lainnya (n=62) menggunakan injeksi lokal lidokain-HCl untuk anestesi selama penjahitan perineum. Nyeri diukur dengan visual analog scale (VAS) untuk 5 menit pertama selama penjahitan perineum. Analisis statistik dilakukan dengan uji numerik komparatif tidak berpasangan dengan uji t independen antara kedua kelompok dengan tingkat kemaknaan p<0,05. Data disajikan sebagai rerata ± standar deviasi (SD). Hasil: Tidak terdapat perbedaan signifikan skor nyeri antara kelompok  lidokain-prilokain topikal dan kelompok injeksi lidokain-HCl (5,66 ± 1,07 vs 5,56 ± 1,5; p = 0,473). Kesimpulan : Efektifitas lidokain-prolikain topikal untuk mengurangi nyeri sama dengan injeksi lidokain-HCl selama penjahitan robekan perineum tingkat dua postpartum pervaginam. Kata kunci : Lidokain-prolikain topical, lidokain-HCl injeksi, nyeri, penjahitan perineum, persalinan normal

The Association of Creactive Protein Levels in Second Trimester of Pregnancy with Preeclampsia Nasruddin, Zulfaekasari; Lukas, Efendi; Malinta, Umar; Chalid, Maisuri T
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To determine C-reactive protein in second trimesterof pregnancy women who preeclamptic and non-preeclampticwomen, and to determine the relationship between the level ofC-Reactive protein of trimester two pregnancy and preeclampsiaoccurrence.Methods: This was a prospective study conducted at the policlinicsof network of academic hospitals of the Department of Obstetricsand Gynecology of Faculty of Medicine, Universitas Hasanuddin andpoliclinic of child and mother, and some Public Health Centers inMakassar city from September 2015 - April 2016. The C-reactiveprotein 115 level of pregnant women in pregnancy age of 24-28weeks was checked, whether the subjects underwent preeclampsiauntil the childbirth process. Statistics analysis used Fisher’s exacttest and Mann Whitney test.Results: The result indicate that 9 subjects (7.8%) developedpreeclampsia and 106 subjects did not become preeclampsia. Thelevel of C-Reactive protein increased in preeclampsia group comparedto non preeclampsia group i.e 5.05  1.153 : 3.36  0.265,but statistically the result is not significant (value p>0.05).Conclusion: The average score of C-Reactive protein of preeclampsiagroup is 33.5% higher than non-preeclampsia group,even though these results cannot be used as the score to predictthe preeclampsia occurrence.Keywords: C-reactive protein, preeclampsia, second trimesterpregnancy

The Association of Creactive Protein Levels in Second Trimester of Pregnancy with Preeclampsia Malinta, Umar; Chalid, Maisuri T; Nasruddin, Zulfaekasari; Lukas, Efendi
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To determine C-reactive protein in second trimesterof pregnancy women who preeclamptic and non-preeclampticwomen, and to determine the relationship between the level ofC-Reactive protein of trimester two pregnancy and preeclampsiaoccurrence.Methods: This was a prospective study conducted at the policlinicsof network of academic hospitals of the Department of Obstetricsand Gynecology of Faculty of Medicine, Universitas Hasanuddin andpoliclinic of child and mother, and some Public Health Centers inMakassar city from September 2015 - April 2016. The C-reactiveprotein 115 level of pregnant women in pregnancy age of 24-28weeks was checked, whether the subjects underwent preeclampsiauntil the childbirth process. Statistics analysis used Fisher’s exacttest and Mann Whitney test.Results: The result indicate that 9 subjects (7.8%) developedpreeclampsia and 106 subjects did not become preeclampsia. Thelevel of C-Reactive protein increased in preeclampsia group comparedto non preeclampsia group i.e 5.05  1.153 : 3.36  0.265,but statistically the result is not significant (value p>0.05).Conclusion: The average score of C-Reactive protein of preeclampsiagroup is 33.5% higher than non-preeclampsia group,even though these results cannot be used as the score to predictthe preeclampsia occurrence.Keywords: C-reactive protein, preeclampsia, second trimesterpregnancy

Lidocaine Prilocaine Cream versus LidocaineHCL Injection for Pain Relief during Second Degree of Perineal Tear Suturing after Vaginal Delivery: A Comparative Study Rahmawati, Rahmawati; Lotisna, David; Abdullah, Nusratuddin; Chalid, Maisuri T; Tessy, Telly
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Abstract Objective : To compare the effectiveness of topically applied lidocaine-prilocaine cream with lidocaine-HCl injection in the reduction of pain during second degree of perineal tear suturing after vaginal delivery. Methods : One hundred and twenty-four of women with second degree of perineal tear after vaginal delivery were enrolled in this randomized clinical trial. Women were assigned randomly to have either application of lidocaine-prilocaine cream (n=62) or local injection of lidocaine-HCl (n=62) for anesthetic during perineal suturing. Pain measured with viasual analog scale (VAS) for the first 5 minutes during the perineal suturing. Statistical analysis was performed by comparative analytic numerical unpaired with independent t test between the two groups and significance was assessed at p<0.05. Data were presented as mean ± standard deviation (SD). Results : There was no significantly different of pain score between lidocaine-prilocaine cream and lidocaine-HCl injection group (5.66±1.07 vs 5.56±1.5; p=0.473). Conclusion : Application of lidocaine-prolicaine cream as effective as injection of lidocaine for reducing pain during second degree of perineal tear suturing after vaginal delivery. Keywords : Lidocaine-prilocaine cream, lidocaine-HCl injection, pain, perineal suturing, vaginal delivery     Abstrak Tujuan: Untuk membandingkan efektivitas antara lidokain-prilokain topikal dan lidokain-HCl injeksi dalam mengurangi nyeri selama penjahitan luka perineum tingkat dua setelah persalinan normal. Metode: Seratus dua puluh empat perempuan dengan robekan perineum tingkat dua postpartum pervaginam mengikuti uji coba klinis secara acak ini. Enam puluh dua perempuan (n=62) menggunakan lidokain-prilokain topikal dan 62 perempuan lainnya (n=62) menggunakan injeksi lokal lidokain-HCl untuk anestesi selama penjahitan perineum. Nyeri diukur dengan visual analog scale (VAS) untuk 5 menit pertama selama penjahitan perineum. Analisis statistik dilakukan dengan uji numerik komparatif tidak berpasangan dengan uji t independen antara kedua kelompok dengan tingkat kemaknaan p<0,05. Data disajikan sebagai rerata ± standar deviasi (SD). Hasil: Tidak terdapat perbedaan signifikan skor nyeri antara kelompok  lidokain-prilokain topikal dan kelompok injeksi lidokain-HCl (5,66 ± 1,07 vs 5,56 ± 1,5; p = 0,473). Kesimpulan : Efektifitas lidokain-prolikain topikal untuk mengurangi nyeri sama dengan injeksi lidokain-HCl selama penjahitan robekan perineum tingkat dua postpartum pervaginam. Kata kunci : Lidokain-prolikain topical, lidokain-HCl injeksi, nyeri, penjahitan perineum, persalinan normal

A Case Report of Thoraco-Omphalopagus Conjoined Twins: The Downfall of the Separated Hearts Safira, Siti Anissa; Chalid, Maisuri T; Madya, Fatmawati
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.591

Introduction: Thoraco-omphalopagus conjoined twins are a rare occurrence of monozygotic pregnancy that involves fusion of the anterior thorax and abdomen. This type presents a variety of cardiac anomalies, which contribute to its generally unfavorable prognosis.Case Presentation: A 32-year-old multigravida with Gravida 6, Para 4, and Abortus 1 was referred at 28 weeks of gestation. Ultrasonography revealed thoracoomphalopagus-conjoined twins in which the fetuses joined ventrally. Prenatal MRI revealed the sharing of a single liver, omentum, and diaphragm. Partial fusion was observed in the sternal bone, pericardium, and anterior wall of the hearts, but with separated heart chambers and unsynchronized heartbeats. Classical cesarean section was performed at 38 weeks of gestational age. Histopathology revealed a single placenta with one umbilical cord, suggesting monochorionic– monoamniotic pregnancy. Healthy female babies were born with a combined weight of 5400 g. Post-delivery echocardiography revealed a cardiac anomaly characterized by malposition of the great arteries in a twin. After 13 h of close monitoring in the NICU, the twins died due to cardiac complications.Conclusion: The management of pregnancy involving thoraco-omphalopagus conjoined twins requires a comprehensive and multi-disciplinary approach aiming to provide holistic care, addressing complex medical risks, and ethical dilemmas associatedwith these twins.Laporan Kasus Mengenai Kembar Siam Torako-Omfalopagus: Prognosis Buruk pada Jantung yang TerpisahAbstrakPendahuluan: Kembar siam thoraco-omphalopagus adalah kejadian langka pada kehamilan monozigot yang melibatkan penyatuan antara toraks dan abdomen anterior. Tipe ini diketahui dapat disertai adanya kelainan jantung yang berkontribusi terhadap prognosis yang umumnya kurang baik.Presentasi Kasus: Multigravida berusia 32 tahun dengan Gravida 6, Para 4, Abortus 1, dirujuk pada usia kehamilan 28 minggu. Ultrasonografi menunjukkan kembar siam torako-omfalopagus di mana janin menyatu secara ventral. MRI prenatal memperlihatkan adanya fusi organ hati, omentum dan diafragma. Di sisi lain, fusi parsial diamati pada sternum, perikardium, dan dinding anterior jantung, dengan ruang jantung terpisah dan detak jantung yang tidak bersifat sinkron.Seksio sesarea klasik dilakukan pada usia kehamilan 38 minggu. Histopatologi menunjukkan plasenta tunggal dengan satu tali pusat sugestif kehamilan monokorionik-monoamniotik. Dua bayi perempuan sehat lahir dengan berat kombinasi 5.400 gram. Ekokardiografi pascasalin menunjukkan adanya anomali jantung berupa malposisi arteri besar pada salah satu bayi. Setelah 13 jam observasi ketat di NICU, kedua bayi kembar meninggal akibat komplikasi jantung.Kesimpulan: Penatalaksanaan kehamilan kembar siam thoraco-omphalopagus memerlukan pendekatan komprehensif dan multidisiplin yang bertujuan untuk memberikan perawatan holistik, mengatasi risiko medis, dan dilema etika yang terkait.Kata kunci: Kembar Siam; Kembar Monozigotik; Thoraco-omphalopagus

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