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All Journal Jurnal Kedokteran Brawijaya Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Berita Kedokteran Masyarakat
Sitti Wahyuni
Faculty of Medicine University of Hasanuddin/ Dr. Wahidin Sudirohusodo Hospital Makassar
Health Professions Medicine & Pharmacology Nursing Public Health

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Helminth Infection in Pregnancy: Effect on Serum Albumin Level and Pregnancy outcome Ridwan, Steven; Wahyuni, Sitti; Chalid, Maisuri T
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (147.415 KB) | DOI: 10.32771/inajog.v3i1.21

Abstract

Objective: To determine the prevalence of helminth infection in pregnant women and its effect on albumin levels and pregnancy outcome. Method: A prospective cohort study was conducted on third trimester pregnant women presenting for antenatal care in several hospitals in Makassar. Information on subject demography was recorded using short questionnaire. Stool samples were collected to determine the presence of helminth infection. Albumin levels were measured from maternal blood and cord‐blood. Outcome of pregnancy was assessed upon delivery. Result: The prevalence of helminth infection in our subjects was 22.8%. Among 21 infected women, 17 were infected with Ascaris lumbricoides (80.9%), one with Trichuris trichiura and three with both Ascaris and Trichuris. The mean Ascaris lumbricoides intensity was 1769.3 epg (Range = 24‐11.688 epg). Helminth infections have no effect on either maternal or neonatal albumin levels (p=0.748 and p=0.480, respectively). Although it was not found to be significant (p>0.05), helminth infection seems to affect gestational age (OR 2.06, 95% CI 1.48‐2.86) and birth weight (OR 2.18, 95% CI 1.52‐3.14). Neonatal albumin level and pregnancy outcome were not affected by maternal albumin level. Conclusion: Helminth infection seems to affect pregnancy outcome in pregnant women in Makassar, but not through influence of albumin. Factors other than albumin level may responsible for such condition.
Infeksi Cacing Tidak Berpengaruh terhadap Kadar Transforming Growth Factor (TGF)-β dan Kejadian Dermatitis Atopik pada Anak Mukhasin, Nadiah Soleman; Wahyuni, Sitti; Ilyas, Faridha S; Amin, Safruddin; Satriono, R; Tabri, Farida
Jurnal Kedokteran Brawijaya Vol 28, No 3 (2015)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1063.152 KB) | DOI: 10.21776/ub.jkb.2015.028.03.10

Abstract

Infeksi cacing melalui kemampuannya memacu proliferasi sel T regulator dilaporkan dapat mempengaruhi manifestasi klinik dari alergi. Selain Interleukin (IL)-10, Transforming Growth Factor (TGF)-β merupakan sitokin yang di lepaskan oleh sel T regulator. Penelitian ini bertujuan untuk melihat pengaruh infeksi cacing terhadap kejadian dermatitis atopik (DA) melalui TGF-β. Penelitian ini dilakukan di beberapa rumah sakit pendidikan Fakultas Kedokteran Universitas Hasanuddin. Dermatitis atopik (DA) didiagnosis dengan menggunakan kriteria William, ada dan beratnya infeksi cacing diperiksa dengan metode Kato Katz dan kadar TGF-β serum diukur menggunakan metode ELISA.  Sebanyak 80 anak usia 2-7 tahun berpartisipasi pada penelitian ini. Partisipan dibagi menjadi kelompok DA (30 anak) dan non-DA (50 anak). Persentasi infeksi cacing adalah 21,2% (17/80) dengan intensitas infeksi yang ringan. Infeksi cacing tidak mempengaruhi kadar TGF-β, demikian juga infeksi cacing serta kadar TGF-β tidak mempengaruhi kejadian DA. Penelitian ini menyimpulkan bahwa infeksi cacing dengan intensitas ringan tidak mempengaruhi kadar TGF-β maupun kejadian DA pada anak di Makassar.Kata Kunci: Dermatitis atopik, infeksicacing, TGF-β
Adverse reactions following COVID-19 immunization in children of elementary school age Yusuf, Yenni; Junaedi, Ari Andini; Mutmainnah; Fadhilah, Nur Azizah; Wahyuni, Sitti
BKM Public Health and Community Medicine Vol 40 No 02 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.v40i02.9712

Abstract

Purpose: Due to the low rate of parent acceptance of vaccines, this study was conducted to evaluate post-vaccination adverse events among elementary school students. Methods: This survey took place in the Manggala Subdistrict of Makassar City. The study was conducted from September to October 2022 by distributing a paper-based questionnaire regarding the COVID-19 vaccines. Results: Of 129 respondents, the age range was 7-12 years. Sixty-five percent of respondents received the first vaccine shot in January or February, with a 4-week interval of the second dose among 46.5% of children. The vaccine administered was CoronaVac from Sinovac. The most common adverse events were injection pain (45-48%) and fever (15-17%). The other side effects were itching, swelling, fever, and shortness of breath. Around 17-18 % of respondents did not have any adverse reactions. There is no increase in the risk for younger children (years 1-3) compared with older children (years 4-6). Conclusion: The children reported only mild adverse events such as injection pain, weakness, and fever. The CoronaVac has minimal side effects among elementary school children.
Co-Authors Fadhilah, Nur Azizah Farida Tabri Faridha S Ilyas Fatimah, Nur Istiqamah Junaedi, Ari Andini Layuk, Nurrahma Maisuri T Chalid, Maisuri T Mutmainnah Nadiah Soleman Mukhasin R Satriono Safruddin Amin SHARVIANTY ARIFUDDIN, SHARVIANTY Steven Ridwan, Steven Supra Wimbarti Yusuf Yenni