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All Journal Althea Medical Journal Jurnal Sistem Kesehatan Jurnal Penyakit Dalam Indonesia
Hendarsyah Suryadinata
Department Of Internal Medicine, Faculty Of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung
Health Professions Medicine & Pharmacology Public Health

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Geographical Factors in Diagnostic Delay among Multidrug Resistant Tuberculosis Patients Nunuy Nuraeni; Hendarsyah Suryadinata; Bony Wiem Lestari
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Diagnostic delay is a  factor that can increase the high burden of multi-drug resistant tuberculosis (MDR-TB). Xpert Mycobacterium tuberculosis/Rifampicin known as Xpert is a rapid diagnostic test to detect MDR-TB. Diagnostic delay defined  the duration between a positive result of Acid Fast Bacilli (AFB) smear and positive result of MDR-TB by Xpert examination. This study aimed to compare the analysis of the geographical factors in the diagnostic delay of MDR-TB patients at Dr. Hasan Sadikin General Hospital as the top referral hospital in West Java Indonesia.Methods: This study was conducted in the period July−December 2016 using cross sectional design. A total of 152 MDR-TB patient data were collected from medical records of MDR-TB patients registered in MDR-TB clinic at Dr. Hasan Sadikin General Hospital in the period 2015−2016.  The socio-demographic characteristics were collected and analyzed descriptively The diagnostic delay among MDR-TB patients was analyzed by Mann Whitney test.Results: Diagnostic delay of MDR-TB patients was 15 days in median, with a minimal and maximal delay of 2−140 days. There was a significant difference of diagnostic delay between  patients from Bandung with a median of 9(2-135) days and patients from outside of Bandung with a median of 18(2-140) days, with p<0.01.Conclusions: MDR-TB patients from outside Bandung have a longer diagnostic delay than patient from Bandung . A further expansion of using Xpert as a rapid diagnostic test for MDR-TB patient is needed.
Comorbidity among Hospitalized Patients with Chronic Obstructive Pulmonary Disease in a Teaching Hospital, West Java Indonesia Dini Qurrotu Aini; Hendarsyah Suryadinata; R. B. Soeherman Herdiningrat
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Background: One of the most important causes that can increase the risk of hospitalization and death in  chronic obstructive pulmonary disease is comorbidity. The aim of this study was to identify the proportion of comorbidity among hospitalized patients with chronic obstructive pulmonary disease in a teaching hospital, West Java, Indonesia, from January to December 2012.Methods: A descriptive study was conducted from  September to November 2013 in Internal Medicine Department of Dr. Hasan Sadikin General Hospital Bandung. The study used 107 medical records that consisted of data about patients with chronic obstructive pulmonary disease (COPD) who were hospitalized between January to December 2012. The medical records were collected using simple random sampling. Variables identified in this study were characteristics of the patients (age, sex, and smoking history) and comorbidity events. Comorbidity events were coronary artery disease (CAD), lung cancer, diabetes mellitus (DM) type 2, anemia, dyslipidemia, osteoporosis, depression, pulmonary artery hypertension (PAH), andhypertension. Age variable was divided into 3 categories with interval 20 years. All collected data were presented in frequency distribution.Results: Most of the patients in this study were 50–69  years old, male, and had smoking history. The highest proportion of comorbid condition was hypertension, followed by anemia and coronary artery disease.Conclusions: Patients with COPD have one or more other diseases (comorbidity). Three most frequent comorbidities are hypertension, anemia, and coronary artery disease. [AMJ.2015;2(4):485–91] DOI: 10.15850/amj.v2n4.632
Gambaran Status Nutrisi pada Pasien Tuberkulosis di Rumah Sakit Umum Pusat Hasan Sadikin Bandung Farah Eka Salsabela; Hendarsyah Suryadinata; Insi Farisa Desy
Jurnal Sistem Kesehatan Vol 2, No 2 (2016): Volume 2 Nomor 2 Desember 2016
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.78 KB) | DOI: 10.24198/jsk.v2i2.11257

Abstract

Proporsi gizi kurang pada pasien tuberkulosis (TB) dewasa masih tinggi di negara-negara berkembang. Hal ini akan menyebabkan permasalahan kesehatan yang lebih serius, jika tidak teridentifikasi dengan segera. Penelitian ini bertujuan untuk mengetahui gambaran status nutrisi berdasarkan karakteristik pasien TB dewasa rawat jalan di Klinik Directly Observed Treatment Short-course (DOTS) Rumah Sakit Hasan Sadikin (RSHS). Penelitian ini menggunakan metode potong lintang. Data diambil dari 107 rekam medis online (Sistem Informasi Rumah Sakit: Admission dan Klinik Rawat Jalan) dan Kartu Pengobatan Pasien TB (Formulir TB.01) pada pasien TB dewasa rawat jalan dalam periode Juni 2015 hingga Oktober 2016. Informasi mencakup identitas pasien (nama, nomor rekam medis, umur, pekerjaan, pendidikan, dan sistem pembayaran), diagnosis, serta berat dan tinggi badan yang diukur saat didiagnosa mengalami TB.Proporsi gizi kurang adalah tiga puluh lima persen (35 %). Enam puluh dua persen (62 %) pasien tidak bekerja dan sembilan puluh persen (90 %) pasien terdaftar sebagai pasien asuransi kesehatan. Enam puluh lima persen (65 %) pasien mengalami gizi kurang dan tidak bekerja. Proporsi gizi kurang masih cukup tinggi (35 %) pada pasien-pasien yang mengalami TB. Hasil dari penelitian ini dapat memberikan landasan penatalaksanaan yang lebih efektif dan meningkatkan angka kesembuhan pada pasien TB dewasa. Kata Kunci: Gizi kurang, pasien rawat jalan, tuberkulosis
Gambaran Klinis Pasien Terduga Tuberkulosis Paru Resisten Obat (TB-RO) dengan Kolonisasi Candida sp. di Rumah Sakit Hasan Sadikin Bandung Zalfa, Hasna Rafifah Zahira; Kulsum, Iceu Dimas; Suryadinata, Hendarsyah; Chrysanti, Chrysanti; Dewi, Intan Mauli Warma
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 1
Publisher : UI Scholars Hub

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Introduction. Candida sp. is a fungus that lives as a commensal in human body, but may cause infection upon immune suppression. The decrease in immunity due to TB infection and long-term use of antibiotics in TB patients may increase the risk of the Candida sp. colonization in patient. Data regarding the prevalence of Candida sp. colonization in TB patients and its impact has not been widely reported. This study was conducted to determine the prevalence and clinical characteristics of presumptive drug-resistance TB patients with Candida sp. colonization. Methods. A cross-sectional study was conducted using secondary data from a previous study in 2018 at the DR-TB clinic in Hasan Sadikin General Hospital Bandung, Indonesia. Patients who were included in the study were aged 18 years or above, presented with pulmonary TB symptoms, and had minimum 5 months of TB treatment history. Candida sp. growth on sputum was examined by culture on CHROMagar® media. Results. One hundred and twenty-two patients met the inclusion and exclusion criteria. The prevalence of Candida sp. colonization in presumptive drug-resistance TB patients was 54.9%. The species found were mostly Candida albicans (71.6%), Candida glabrata and Candida parapsilosis (14.9%), and Candida tropicalis (5.9%). The predominant symptoms of pulmonary tuberculosis included a persistent cough lasting two weeks or longer and productive cough (100%), while the most frequently observed abnormalities on radiological scans were nodules and patchy lesions (98.5%). There were no significant differences between patients with positive and negative Candida sp. colonization. Conclusions. More than 50% of presumptive drug-resistant TB patients at the MDR-TB clinic in Hasan Sadikin General Hospital had positive results of Candida sp. culture on their sputum. The most common clinical manifestations were coughing for 2 weeks or more, productive cough, hemoptysis, fever, chest pain, shortness of breath, night sweats, weight loss, and reduced appetite. Future studies should be conducted to determine the long-term outcome of fungal colonization in these patients.
Co-Authors . SETIAWAN Amalia Rizki Ramadhani Ambrosius Purba Ambrosius Purba Atika Andianti Bony Wiem Lestari Bony Wiem Lestari Bony Wiem Lestari, Bony Wiem Chrysanti Chrysanti Dewi, Intan Mauli Warma Dian Nuryanda Dini Qurrotu Aini Dini Qurrotu Aini, Dini Qurrotu Farah Eka Salsabela Farah Eka Salsabela, Farah Eka Iceu Dimas Kulsum Insi Farisa Desy Insi Farisa Desy, Insi Farisa Nunuy Nuraeni Nuraeni, Nunuy Nuryanda, Dian Pradipta, Shalahuddin Galih R. B. Soeherman Herdiningrat R. B. Soeherman Herdiningrat, R. B. Soeherman Ramadhani, Amalia Rizki Setiawan Setiawan Shalahuddin Galih Pradipta Vita Murniati Tarawan Zalfa, Hasna Rafifah Zahira