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Effectiveness of Lockdown in Reducing the Spread of COVID-19 Adyati Satya Puspita; Judya Sukmana; Lestari Dewi; Erina Yatmasari
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16656

Abstract

At the end of 2019, a mysterious outbreak appeared, forming an atypical pneumonia suspected of originatingfrom an animal market in Wuhan China. The outbreak is a new type of coronavirus which is named asCOVID-19 disease (2019 – nCoV, Novel Coronavirus). COVID 19 disease is a viral infection caused bySARS-CoV-2, namely the acute respiratory syndrome coronavirus 2 which emerged in Wuhan, China.Vaccines and antiviral drugs have not been found, meanwhile COVID-19 are prevented by using nonpharmacologicalinterventions, one of the actions taken by several countries is to create policy protocolssuch as lockdowns.The results of this study indicate that lockdown is effective in reducing the spread of COVID -19, it can beseen from the significant decrease in R0 and Rt, <1 in several countries after lockdown such as UK 0.99(0.96–1.02), Italy 0.89 (0.87–0.91), French 0.76 (0.72–0.82) and Spain 0.74 (0.71–0.78) which means thatsomeone who is infected cannot infect other people and the disease will die (disappear). The value of Rt alsoshows a consistent decline Rt to <1 (0.88) after 2 weeks of lockdown in Italy.The conclusion from this literature show that lockdowns can reduce the spread of COVID-19 which isshown by the number of incidents before and after the lockdown which has decreased to zero cases in China.The decline in cases also occurred in Europe although at the beginning of the lockdown it was not significantbut it was increasingly effective and continued to be significant after the lockdown was imposed.
The Effect of COVID-19 on Blood Pressure Control in Hypertension Patients– A Literature Review Raditya Manusakti; Judya Sukmana; Wachjudi Kurniaj; Liliawanti
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17035

Abstract

COVID-19 is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2). First identifiedin Wuhan, China, in December 2019, and declared an International Public Health Emergency in January2020, the WHO declared a pandemic in March 2020. Hypertension, a disease that has long been a problemfor most people in Indonesia and around the world . COVID-19 can affect blood pressure control for peoplewith hypertension due to obstruction of the RAAS system. This research was conducted to find out whateffect COVID-19 has on blood pressure control in people with hypertension. In the condition of COVID-19patients with comorbid hypertension, SARS-CoV-2 which attacks ACE2 can eliminate the role of ACE2 inthe RAAS system. Inhibition of ACE2 can also cause buildup of angiotensin II which has a vasoconstrictiveeffect. This results in the absence of homeostasis in the blood pressure control system and makes bloodpressure conditions that continue to be at high pressure.
Hubungan Perilaku Merokok dengan Angka Kejadian Tuberkulosis Paru di Puskesmas Kenjeran Surabaya Auliadina Tetrania Darmastuti; Judya Sukmana; Nita Pranitasari
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 1 No. 2 (2020): Oktober
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.151 KB) | DOI: 10.37148/comphijournal.v1i2.9

Abstract

Introduction: Pulmonary tuberculosis (TB) is caused by Mycobacterium tuberculosis and has infected one-third of all human populations around the world, so it has been a global problem. Smoking is one of the risk factors that cause a high mortality rate in TB sufferers. Aim of study: This study aims to evaluate the relationship between smoking behaviur and the incidence of Pulmonary TB in the Kenjeran’s Primary Health Center 2017-2018. Method: This study is observative analytic research with a cross-sectional design. The population in this study were Pulmonary TB in the medical record of the Kenjeran Health Center in 2017-2018. The sample was taken based on the purposive sampling method. 71 people were suffered from pulmonary TB obtained as samples. Results and Discussions: The results of the statistical analytic stated that there was no significant correlation between smoking and the incidence of pulmonary TB, the p-value was 0,601 found in the data analysis (p > 0,05). From 71 respondents, 56 respondents (80,3%) were BTA + patients and 15 respondents (19,7%) were BTA - patients. Based on smoking behavior, there were 56 respondents (78,9%) non-smokers. Based on most sexes, 50 respondents were male. Based on the age group, most of them were in the 17-35 years, amounting to 44 respondents (62%). Conclusions: The conclusion of this research is that there is no relationship between smoking behavior and the incidence of pulmonary TB in the Kenjeran Primary Health Center in 2017-2018.
Pengaruh Alginat dari Alga Coklat (Sargassum sp) terhadap Penyembuhan Luka Diabetes Melitus pada Tikus yang Diinduksi Streptozotocin TAUFAN ANTARISKA; NITA PRANITASARI; JUDYA SUKMANA; IRMA ANDRIANI PASARIBU
HANG TUAH MEDICAL JOURNAL Vol 19 No 2 (2022): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v19i2.212

Abstract

Diabetes mellitus is a degenerative disease which its prevalence increases over time, this disease is often overlooked, thereby increasing complications. Uncontrolled long-term hyperglycemia will cause sensory nerve and blood vessel function disorders. Disruption of the non-healing chronic wound reparation process due to this condition will result in excessive ROS level accompanied by secondary infection, increasing the risk of amputation and death. On the other hand, alginate produced by the cell walls of brown algae (Sargassum sp) is believed to be able to increase the formation of new blood vessels, balance excessive ROS level, and prevent infection at the wound site. This study was conducted to examine the effect of topical alginate on wound healing in diabetic rats. The population in this study includes articles that discuss wounds healing process in diabetic rats induced by streptozotocin (STZ) given alginate therapy. The research sample was obtained from data that had been affixed in 15 international research articles indexed by Scimago from 2016 to 2021. The method used in this study was a literature review. This research took place from May to December 2021.The results of the 15 articles reviewed revealed that alginate could improve wound healing in STZ-induced diabetic rats, this was indicated by decrease in duration of wound closure and inflammation, increase proliferation of epithelial cells and collagen density, and prevent the occurrence of secondary infection at the wound site. Based on these findings, it was concluded that topical administration of alginate had a good effect on the wound healing process of STZ-induced diabetic rats. Keywords: Alginate; diabetic mice; streptozotocin; wound healing