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Eka Susanto
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Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Public Health Social Sciences Transportation Other

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BELAJAR MENGELOLA MUSEUM DARI MuseuM THE LOUVRE, PARIS Vyana Lohjiwa, M.P.Par; Eka Susanto
Warta Pariwisata Vol 18 No 2 (2020): Museum dan Pariwisata
Publisher : Pusat Perencanaan dan Pengembangan Kepariwisataan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1353.052 KB) | DOI: 10.5614/wpar.2020.18.2.15

Abstract

Bagaimana masa depan museum? Akankah sejarah berubah? Pertanyaan ini masih menjadi tanda tanya besar bagi kami. Dari beberapa artikel, teori, serta pengalaman berkunjung ke museum baik dalam negeri maupun luar negeri, kami menemu- kan adanya “gap” antara perencanaan dan aktualisasi pengelolaan museum di Indonesia. Tulisan ini berangkat dari opini kami tentang perkembangan museum di The Louvre Museum Paris
Characteristics and Correlation Between Progesterone Receptors and The Use of Hormonal Contraceptive in Women with Meningioma in dr. Cipto Mangunkusumo National General Hospital Setyo Widi Nugroho; Harris Istianggoro; Fabianto Santoso; David Tandian; Renindra Ananda Aman; Eka Susanto
eJournal Kedokteran Indonesia Vol. 10 No. 2 - Agustus 2022
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23886/ejki.10.161.101-6

Abstract

Meningiomas are the most common primary, intracranial and extra axial tumours, estimated for 30% of all intracranial tumors. The use of hormonal contraceptive is one of the risk factors for meningioma, but the studies still have controversial results. The purpose of this study is to describe the characteristics and to correlate between progesterone receptor and the use of hormonal contraceptive in women diagnosed with brain tumor meningioma. This is a cross-sectional study which collect data in dr. Cipto Mangunkusumo National General Hospital in the year 2017-2018. Patient data collection was obtained through the patient’s medical records, whereas the subjects are women with brain tumors meningioma who have undergone surgery. We found 72 women diagnosed with meningioma; however, only 54 subjects were included in this study. Immunohistochemistry staining were performed to all the 54 subjects and revealed that 53 subjects (98.15%) had positive progesterone receptors and only 1 subject was negative (1.85%). Of the 53 subjects with positive progesterone receptors, 48 subjects used hormonal contraceptive (90.57%), with 43 (89.58%) of them used 3 month injectable contraceptive. There is no correlation between progesterone receptors and the use of hormonal contraceptives in female patients with meningioma brain tumor (p value >0.999, Fisher Test). Keywords: meningioma, hormonal contraception, progesterone receptor.   Karakteristik dan Korelasi antara Progesteron Reseptor dan Penggunaan Kontrasepsi Hormonal pada Perempuan dengan Meningioma di RSUPN Dr. Cipto Mangunkusumo Abstrak Meningioma adalah tumor intrakranial ekstraaksial primer terbanyak dengan perkiraan 30% dari seluruh tumor intrakranial. Penggunaan kontrasepsi hormonal diduga menjadi salah satu faktor risiko meningioma, namun hasil penelitian masih kontroversial. Tujuan penelitian ini adalah mengetahui karakteristik dan korelasi antara progesteron reseptor dan penggunaan kontrasepsi hormonal pada perempuan dengan meningioma. Studi potong lintang ini menggunakan data rekam medis RSUPN dr. Cipto Mangunkusumo pada tahun 2017-2018. Data pasien dikumpuikan melalui rekam medis dimana subyek adalah pasien meningioma intrakranial yang dilakukan operasi. Terdapat 72 perempuan yang didiagnosis meningioma, namun data yang dapat dianalisis adalah 54 subyek. Hasil pewarnaan imunohistokimia didapatkan 53 subyek (98,15%) memiliki reseptor progesteron positif. Dari kelompok reseptor progesteron yang positif, 48 subyek (90,57%) menggunakan kontrasepsi hormonal dengan mayoritas (89,58%) menggunakan kontrasepsi injeksi 3 bulan. Tidak didapatkan korelasi antara reseptor progesteron dengan penggunaan kontrasepsi hormonal pada perempuan dengan meningioma (nilai p >0,999, Uji Fisher). Kata kunci: meningioma, kontrasepsi hormonal, reseptor progesteron
HEPATIC METASTATIC MENINGIOMA FOLLOWING REPEATED INTRACRANIAL REMOVAL SURGERIES : Hepatic Metastatic Meningioma Audrey Clarissa; Tiara Aninditha; Eka Susanto; Kemal Fariz Kalista; David Tandian; Irma Savitri Madjid; Henry Riyanto Sofyan
Acta Neurologica Indonesia Vol. 3 No. 01 (2025): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v3i01.41

Abstract

Introduction : Meningioma is mostly benign. With appropriate management, it may have a good prognosis. However, it may reoccur and metastasize in <1% of all cases. Studies describing re-occurrences of meningioma and extracranial metastasis, especially to the liver, are limited. Case Report : A 54-year-old female with secondary headache, cognitive impairment, blindness in the left eye, and paresis of the left facial nerve due to recurrent left spheno-orbital meningioma with scalp invasion had undergone four tumor removal surgeries. Previous histopathological findings were atypical meningioma (2017) and transitional meningioma (2023). A suspicion of a new primary tumor arose as an increase in transaminase and multiple liver nodules were observed despite being an asymptomatic patient. Histology and immuno-histochemistry from the intracranial tumor was an atypical meningioma, and cancer in the liver had a similar immunohistochemistry profile as the intracranial tumor, suggesting meningioma metastasis. Discussion : Recurrences were more prevalent in higher histologic grading, which can lead to serial operations, higher complication rates, and morbidities. While the lungs are the most common site for metastasis, hepatic metastasis is thought to be underestimated as patients are often asymptomatic. Factors such as scalp and brain invasion, blood vessel proximity, meningioma recurrences, and subtotal resection increase the risk of metastasis. To date, there are no specific guidelines on metastasis treatment. Conclusion : Meningioma can re-occur and metastasize to distant organs despite its usual benign characteristics. Aggressive tracking should be implemented in females with recurrent meningioma and scalp involvement
RARE CASE OF LEPTOMENINGEAL METASTASES FROM POORLY DIFFERENTIATED PAROTID CARCINOMA : RARE CASE OF LEPTOMENINGEAL METASTASES Tiara Aninditha; Dyah Ayu Puspita Anggarsari; Radius Kusuma; Eka Susanto; Erwin Danil Yulian; Irma Savitri; Henry Riyanto Sofyan
Acta Neurologica Indonesia Vol. 3 No. 01 (2025): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v3i01.43

Abstract

exceedingly rare and challenging to diagnose, requiring confirmation via imaging and cerebrospinal fluid (CSF) cytology. Clinical signs like secondary headache often signal critical intracranial involvement. Case Report: A 27-year-old woman presented with severe headache, dizziness, and vomiting. She had a history of poorly differentiated parotid carcinoma with liver metastases and prior chemotherapy (CAF: cisplatin, doxorubicin, and fluorouracil). Physical exam revealed mild peripheral facial nerve palsy, ataxic gait, and tremor. High-dose dexamethasone and acetaminophen provided headache relief. CT brain imaging showed vasogenic edema with leptomeningeal enhancement in the right cerebellum and a 46% reduction in the parotid lesion. MRI of the nasopharynx identified leptomeningeal enhancement, notably in the right cerebellum, suggesting metastasis, along with fourth ventricle narrowing and ventricular dilation. CSF cytology revealed poorly differentiated malignant cells with pleomorphic nuclei. Craniospinal irradiation was planned. Discussion: Leptomeningeal metastasis is an uncommon parotid carcinoma complication. Secondary headache, diffuse and bilateral, typically affects the C2-C3 dermatome and is accompanied by dizziness. Symptom relief with high-dose dexamethasone was observed. Definitive LM diagnosis combines CSF cytology and MRI leptomeningeal enhancement. As chemotherapy options for LM from parotid carcinoma are limited, craniospinal irradiation is the preferred treatment. Conclusion: Leptomeningeal metastasis from poorly differentiated parotid carcinoma is extremely rare, confirmed by clinical signs, imaging, and CSF analysis. Severe secondary headache is a key indicator, and delayed diagnosis could prove fatal.
Secondary Hypogonadism in Recurrent Adamantinomatous Craniopharyngioma: Fertility Evaluation and Management Adeputri Tanesha Idhayu; Tri Juli Edi Tarigan; Em Yunir; Setyo Widi Nugroho; Eka Susanto
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 2 (2024): InaJEMD Vol. 1, No. 2
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Craniopharyngioma is an intracranial tumor with pituitary hormone deficiencies and affects 40% of gonadotropins deficiency. Gonadotropin deficiency causes secondary hypogonadism and male infertility which need to investigation for male infertility therapy options. A 22-year-old man presented with history of intermittent headaches, visual impairment, mild left- side hemiparesis, and developed erectile dysfunction. On clinical examination, there was abnormal penile and testicular size. The radiological examination showed a solid intrasellar mass with cystic lesion. The histological diagnosis was adamantinoma Tous craniopharyngioma. The hormonal evaluation showed low testosterone level, LH and FSH, and semen analysis showed azoospermia. The human chorionic gonadotropin stimulation test showed testosterone increase times from baseline, but evaluation semen test remained azoospermia. Craniopharyngioma morbidity is associated with tumor related and or treatment-related risk factors such as hormone deficiencies. Pituitary hormone deficiencies have been reported in 54–100% of patients that affect secretion of growth hormone, gonadotropin, TSH and ACTH. Gonadotropin deficiency associated with infertility in men. In this case, gonadotropin deficiency was due to the tumor because the symptoms had developed before surgery. Hypogonadism in this case occurs after puberty and he willing to have offspring. The hormonal therapy is effective in restoring spermatogenesis relates to the regulatory of the hypothalamic pituitary gonadal axis. The administration of HCG alone or combined with FSH, restores spermatogenesis of patients with hypogonadotropic hypogonadism, with reported pregnancy rates of up to 65%. Gonadotropin stimulation therapy will be planned after ruling out seminal tract obstruction and testicular fibrosis. Infertility in secondary hypogonadism can be managed with hormone therapy, but a complete investigation is required before starting treatment to determine therapy options.
Profil Wisatawan Nusantara Taman Nasional Gunung Gede Pangrango Eka Susanto; M. Sapari Dwi Hadian; Ute Lies Siti Khadijah
Pusaka : Journal of Tourism, Hospitality, Travel and Business Event Vol. 3, No 1 February (2021)
Publisher : Politeknik Pariwisata Makassar, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33649/pusaka.v3i1.77

Abstract

Taman Nasional Gunung Gede Pangrango (TNGGP) merupakan salah satu destinasi pariwisata di Jawa Barat dengan luas kurang lebih 29 hektar yang berada di tiga kabupaten. Keanekaragaman daya tarik wisata khususnya alam yang ada di TNGGP menjadi salah satu alasan kunjungan wisatawan ke TNGGP, jumlah kunjungan wisatawan tahun 2019 sebanyak 251.222. Dengan kunjungan wisatawan yang konsisten dari tahun ke tahun sementara belum adanya data mengenai profil wisatawan nusantara membuat perencanaan produk wisata dan strategi pemasaran tidak terarah, oleh karena itu diperlukan penelitian mengenai karakteristik wisatawan nusantara yang berkunjung ke TNGGP sehingga memudahkan dalam strategi pemasaran maupun dalam perencanaan kebijakan dan produk wisata TNGGP. Metode penelitian ini menggunakan pendekatan deskriptif kualitatif sedangkan Teknik samplingnya adalah random sampling dengan membagikan kuesioner kepada 50 wisatawan yang kemudian dilakukan Analisis Statistik deskriptif. Hasil penelitian menemukan bahwa profil wisatawan nusantara di TNGGP merupakan wisatawan dengan karakteristik allocentric dan Mid Centric dengan latar Pendidikan yang baik serta relatif baik dari segi ekonomi. Hasil penelitian ini sangat penting untuk pengembangan TNGGP sebagai destinasi wisata, terlebih penelitian yang dilakukan di TNGGP cenderung banyak kepada penelitian produk dan dampak.
Co-Authors Adeputri Tanesha Idhayu Audrey Clarissa David Tandian Dyah Ayu Puspita Anggarsari Em Yunir, Em Erwin Danil Yulian Fabianto Santoso Harris Istianggoro Henry Riyanto Sofyan Irma Savitri Irma Savitri Madjid Kemal Fariz Kalista M. Sapari Dwi Hadian Radius Kusuma Renindra Ananda Aman Setyo Widi Nugroho Tiara Aninditha Tiara Aninditha Tri Juli Edi Tarigan Ute Lies Siti Khadijah Vyana Lohjiwa