Setyo Widi Nugroho
Department Of Neurosurgery Faculty Of Medicine Universitas Indonesia - RSUP Nasional Dr. Cipto Mangunkusuma

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EVALUASI TAJAM PENGLIHATAN DAN INDEKS PROPTOSIS PASIEN MENINGIOMA SPHENOORBITA PASCAOPERASI KRANIEKTOMI Renindra Ananda Aman,* Ryan Rhiveldi Keswani,* Syaiful Ichwan,* Samsul Ashari, Setyo Widi Nugroho*
NEURONA Vol. 37 No. 4 September 2020
Publisher : Neurona Majalah Kedokteran Neuro Sains

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Abstract

INTRODUCTION SPHENOORBITAL MENINGIOMA SOM IS AN EXOPHYTIC TUMOR MASS THAT INFILTRATES THE BONE AT THE SPHENOID WING LATERAL ORBITAL WALLS ORBITAL ROOFS AND EXTENDS TO SUPERIOR ORBITAL FISSURES THE CLASSIC TRIAD OF CLINICAL FEATURES ARE PROPTOSIS DECREASED VISUAL ACUITY AND OPHTHALMOPLEGIA THE OUTCOMES OF OUR POSTOPERATIVE PATIENTS HAVE NOT BEEN EVALUATED BEFORE
HUBUNGAN WAKTU TUNGGU MENUJU OPERASI PENGANGKATAN TUMOR INTRAKRANIAL DENGAN SKALA PERFORMA KARNOFSKY PASCAOPERASI Setyo Widi Nugroho,* Aryandhito Widhi Nugroho,* Renindra Ananda Aman,* Hanif Gordang Tobing*
NEURONA Vol. 37 No. 4 September 2020
Publisher : Neurona Majalah Kedokteran Neuro Sains

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INTRODUCTION THE WAITING TIME TO ELECTIVE INTRACRANIAL TUMOR REMOVAL SURGERY IN INDONESIA IS UNKNOWN LET ALONE ITS ASSOCIATION WITH POSTOPERATIVE FUNCTIONAL OUTCOME
LUARAN PERDARAHAN INTRAVENTRIKEL YANG DILAKUKAN OPERASI DI DEPARTEMEN BEDAH SARAF RSUPN DR CIPTO MANGUNKUSUMO Wismaji Sadewo,* Liza Amelia,* Hanif Gordang Tobing,* Setyo Widi Nugroho,* Syaiful Ichwan,* Samsul A
NEURONA Vol. 35 No. 1 Desember 2017
Publisher : Neurona Majalah Kedokteran Neuro Sains

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INTRODUCTION INTRAVENTRICULAR HEMORRHAGE IVH IS A SPONTANEOUS HEMORRHAGE OCCURRING WITHIN THE VENTRICULAR SYSTEM 3045 OFTEN ASSOCIATED WITH INTRACEREBRAL HEMORRHAGE ICH EVALUATING ACCURATE AND PRECISE DAILY ACTIVITY IN POSTSTROKE PATIENTS IS CRITICAL FOR THE QUALITY OF CARE AND MEASUREMENT OF POSTSTROKE OUTCOMES
Profil Tekanan Darah Normal Tikus Putih (Rattus norvegicus) Galur Wistar dan Sprague-Dawley Setyo Widi Nugroho; Kanti Rahmi Fauziyah; Dondin Sajuthi; Huda Salahudin Darusman
Acta VETERINARIA Indonesiana Vol. 6 No. 2 (2018): Juli 2018
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (621.807 KB) | DOI: 10.29244/avi.6.2.32-37

Abstract

Tikus putih (Rattus norvegicus) merupakan hewan coba yang digunakan untuk penelitian biomedik. Penelitian ini bertujuan untuk memberikan nilai tekanan darah normal tikus putih dengan galur (Wistar dan Sprague-Dawley) dan jenis kelamin yang berbeda melalui pengukuran tekanan darah non-invasive. Pengukuran tekanan darah dengan menggunakan instrumen CODA® pada 20 ekor tikus putih. Profil tekanan darah yang diukur meliputi tekanan darah sistolik, diastolik, tekanan arteri rata-rata, denyut jantung, dan aliran darah pada ekor. Nilai tekanan darah sistolik, diastolik, dan tekanan arteri rata-rata pada galur Sprague-Dawley lebih tinggi secara signifikan (P<0.05) dibandingkan Wistar. Tikus putih galur Sprague-Dawley jantan memiliki profil tekanan darah diastolik dan tekanan arteri rata-rata yang lebih tinggi secara signifikan (P<0.05) dibandingkan betina. Galur Wistar jantan menunjukkan profil tekanan darah yang lebih tinggi dibandingkan betina namun tidak berbeda secara signifikan (P>0.05). Sprague-Dawley jantan menunjukkan hasil tekanan darah diastolik dan tekanan arteri rata-rata yang lebih tinggi secara signifikan (P<0.05) dibandingkan Wistar jantan. Studi ini menekankan pentingnya memilih ras dan jenis kelamin hewan coba tikus dalam studi kardiovaskuler.
Is there any benefit from surgery for giant-dumbbell spinal tumors with prolonged paraplegia and joints contractures? a rare case report Mohamad Saekhu; Eka Susanto; Samsul Ashari; Setyowidi Nugroho
Neurologico Spinale Medico Chirurgico Vol 5 No 1 (2022)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36444/nsmc.v5i1.174

Abstract

The lack of clarity about the opportunities for significant neurologic improvement, coupled with the risk of severe postoperative complications, decompression surgery for patients with giant tumors in the cervical spine accompanied by long-lasting advanced neurological deficits places a heavy moral burden on surgeons. Here we report a three-year follow-up after surgery for an immense spinal neurofibroma in which the patient was bedridden for the past fifteen years. Our findings suggest surgery remains beneficial for patients without major postoperative complications.
Cervical Myelopathy as the Most Common Symptoms in Patients Undergoing C-Spine Surgery in the Spine Division, Department of Neurosurgery, Cipto Mangunkusumo General Hospital, from January 2012 to December 2016 Mohamad Saekhu; Jeremia Prasetya Pardede; Renindra Ananda Aman; Syaiful Ichwan; Wismaji Sadewo; Samsul Ashari; Setyowidi Nugroho
Neurologico Spinale Medico Chirurgico Vol 1 No 1 (2018)
Publisher : Indoscholar

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Abstract

Background: Cervical spine disease has the potential to reduce productivity in affected patients because of myelopathy and mood disorder (e.g. depression) which lead to decreasing of the patient’s quality of life.Objective: This study aims to elaborate on the most frequent symptoms and pathology of C-spine disease in patients who underwent a surgical procedure over the period time from January 2012 to December 2016.Method: This study is a retrospective. All patients who underwent surgery for the C-spine disease are included. The data was obtained from the records in our spine database.Result: The total number of surgical procedures for spine disease over the 5 years was 345 procedures, with 127 procedures in the C-spine which are the second most common procedures of spine surgery in Department of Neurosurgery FMUI. The C-spine diseases were more common in males, aged more than 50 years old. The most frequent disease or pathology is a degenerative disease, and yet, tumour cases show an increasing number and became the most common pathology in the year of 2016. The most common procedure is anterior cervicaldiscectomy and fusion (ACDF).Conclusion: Our study showed that the most common symptoms and pathology are myelopathies and degenerative disease respectively, which has similarity with another study in the term of the mostfrequent pathology and surgical procedure. The finding of the more advanced neurological condition by the time of surgery as the most common symptom is found to be contradictory with other studies in western countries.
THE TREND AND PROFILE OF THE THORACIC SPINE SURGERY IN NEUROSURGERY DEPARTMENT FACULTY OF MEDICINE UNIVERSITAS INDONESIA – RSUP NASIONAL DR. CIPTO MANGUNKUSUMO 2012 – 2016 Muhammad Saekhu; Bismo Nugroho; Samsul Ashari; Renindra A Aman; Hanif G Tobing; Setyowidi Nugroho
Neurologico Spinale Medico Chirurgico Vol 1 No 2 (2018)
Publisher : Indoscholar

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Abstract

Background: Spinal surgery, in general, is increasing in number. The most frequent pathology is degenerative disease, and the most common segment is cervical and lumbar. However, there is limited information concerning the thoracic spine surgeries.Objective: The aim of this study is to describe the trend and profle of the thoracic spine (T-spine) surgeries in the Department of Neurosurgery Faculty of Medicine Universitas Indonesia – RSUP Dr.Cipto Mangunkusumo from 2012 to 2016.Method: This is a retrospective study including all patients who were undergoing T-spine surgery during the period of study from January 2012 to December 2016. The number of T-spine procedureswas recorded and plotted in the trend graph. The data consisting age, gender, indication and procedure of T-spine surgery, and duration of hospital stay were recorded from medical records.Result: In the last fve years, there was an increasing trend of T-spine surgery. A total of 68 surgeries for T-spine performed with 35 female and 33 male subjects. Majority of subjects were aged 41 to 50 years old (28%), with an indication of surgery due to tumours (68%). As many as 76% T-spine surgery was carried out non-instrumented. Duration of hospital stay was 9-13 days.Conclusion: Productive age is the most common age undergoing T-spine surgeries. A spinal tumour is the most frequent indication of the T-spine surgeries
Peran Bone Marrow Mesenchymal Stem cells (BMMSC) dalam Perubahan Seluler Hyperplasia Kelenjar Adrenal Tikus Hipertensi Yanse Yane Rumlaklak; Erni Sulistiawati; Dondin Sajuthi; Sus Derthi Widhyari; Setyo Widi Nugroho
JURNAL KAJIAN VETERINER PROSIDING SEMINAR NASIONAL KE-7
Publisher : FAKULTAS KEDOKTERAN HEWAN UNIVERSITAS NUSA CENDANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jkv.v0i0.1602

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Dalam keadaan hipertensi, hyperplasia merupakan salah satu abnormalitas jaringan yang terlihat yang ditunjukkan dengan peningkatan jumlah sel dalam jaringan atau organ sehingga jaringan atau organ menjadi lebih besar ukurannya dari normal. Tujuan penelitian ini adalah untuk mengetahui efektivitas bone marrow mesenchymal stem cells (BMMSC) terhadap perubahan seluler hyperplasia pada organ kelenjar adrenal tikus hipertensi. Penelitian ini menggunakan sepuluh ekor tikus jantan strain Wistar dengan umur ± 10-12 minggu dan berat badan ± 200-250 gram, dan dibagi menjadi 2 kelompok berbeda yaitu hipertensi BMMSC (+) dan hipertensi BMMSC (-). Tikus dikondisikan hipertensi menggunakan Metode Hashinoto. Nefrektomi kanan dan ligase arteri carotid communis dilakukan pada semua tikus. Tikus disuntik dengan deoxycorticosterone acetate (DOCA), kemudian 0,12% aminopropionitrile fumarate (BAPN) ditambahkan ke dalam air minum. Larutan NaCl 1% diberikan sebagai air minum selama penelitian. Evaluasi tekanan darah hipertensi dilakukan, kemudian tikus-tikus di euthanasia untuk koleksi organ kelenjar adrenal. Organ Kelenjar adrenal di fiksasi dengan formalin 10% dan kemudian diwarnai dengan pewarnaan Periodic Acid Shiff (PAS). Data yang diperoleh kemudian dianalisis secara deskriptif kualitatif. Hasil penelitian ini membuktikan terapi hipertensi dengan menggunakan BMMSC menunjukkan perubahan hiperplasia kearah normal.
Characteristics and Correlation Between Progesterone Receptors and The Use of Hormonal Contraceptive in Women with Meningioma in dr. Cipto Mangunkusumo National General Hospital Setyo Widi Nugroho; Harris Istianggoro; Fabianto Santoso; David Tandian; Renindra Ananda Aman; Eka Susanto
eJournal Kedokteran Indonesia Vol. 10 No. 2 - Agustus 2022
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23886/ejki.10.161.101-6

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Meningiomas are the most common primary, intracranial and extra axial tumours, estimated for 30% of all intracranial tumors. The use of hormonal contraceptive is one of the risk factors for meningioma, but the studies still have controversial results. The purpose of this study is to describe the characteristics and to correlate between progesterone receptor and the use of hormonal contraceptive in women diagnosed with brain tumor meningioma. This is a cross-sectional study which collect data in dr. Cipto Mangunkusumo National General Hospital in the year 2017-2018. Patient data collection was obtained through the patient’s medical records, whereas the subjects are women with brain tumors meningioma who have undergone surgery. We found 72 women diagnosed with meningioma; however, only 54 subjects were included in this study. Immunohistochemistry staining were performed to all the 54 subjects and revealed that 53 subjects (98.15%) had positive progesterone receptors and only 1 subject was negative (1.85%). Of the 53 subjects with positive progesterone receptors, 48 subjects used hormonal contraceptive (90.57%), with 43 (89.58%) of them used 3 month injectable contraceptive. There is no correlation between progesterone receptors and the use of hormonal contraceptives in female patients with meningioma brain tumor (p value >0.999, Fisher Test). Keywords: meningioma, hormonal contraception, progesterone receptor.   Karakteristik dan Korelasi antara Progesteron Reseptor dan Penggunaan Kontrasepsi Hormonal pada Perempuan dengan Meningioma di RSUPN Dr. Cipto Mangunkusumo Abstrak Meningioma adalah tumor intrakranial ekstraaksial primer terbanyak dengan perkiraan 30% dari seluruh tumor intrakranial. Penggunaan kontrasepsi hormonal diduga menjadi salah satu faktor risiko meningioma, namun hasil penelitian masih kontroversial. Tujuan penelitian ini adalah mengetahui karakteristik dan korelasi antara progesteron reseptor dan penggunaan kontrasepsi hormonal pada perempuan dengan meningioma. Studi potong lintang ini menggunakan data rekam medis RSUPN dr. Cipto Mangunkusumo pada tahun 2017-2018. Data pasien dikumpuikan melalui rekam medis dimana subyek adalah pasien meningioma intrakranial yang dilakukan operasi. Terdapat 72 perempuan yang didiagnosis meningioma, namun data yang dapat dianalisis adalah 54 subyek. Hasil pewarnaan imunohistokimia didapatkan 53 subyek (98,15%) memiliki reseptor progesteron positif. Dari kelompok reseptor progesteron yang positif, 48 subyek (90,57%) menggunakan kontrasepsi hormonal dengan mayoritas (89,58%) menggunakan kontrasepsi injeksi 3 bulan. Tidak didapatkan korelasi antara reseptor progesteron dengan penggunaan kontrasepsi hormonal pada perempuan dengan meningioma (nilai p >0,999, Uji Fisher). Kata kunci: meningioma, kontrasepsi hormonal, reseptor progesteron
Spinal dermal sinus coinciding with an infected giant epidermoid cyst in an infant presenting with constipation: a case report Mohamad Saekhu; Eka Susanto; Setyo Handryastuti; Samsul Ashari; Setyowidi Nugroho
Paediatrica Indonesiana Vol 62 No 5 (2022): September 2022
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi62.5.2022.357-63

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Early diagnosis of spinal tumors is a prerequisite for achieving satisfactory neurological recovery. However, rare diseases tend to have a long diagnostic course.1 In addition, the clinical presentation of spinal tumors in most children is not apparent, moreover, spinal tumors may not show clinical symptoms if they are located in the lumbar spine and sized no more than one vertebra.2,3 Clinical presentations caused by tumors in the lumbar spine may include weakness of both limbs, impaired urination, and constipation.