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All Journal Indonesian Journal of Obstetrics & Gynecology Science Jurnal Syntax Transformation Manajemen Pelayanan Kesehatan
Florencia Desiree
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Humanities Dentistry Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Ekspresi Enzim 1 Alfa-Hidroksilase Plasenta yang Rendah sebagai Faktor Risiko Terjadinya Preeklamsia Berat Florencia Desiree; I Wayan Artana Putra; I Wayan Megadhana; Anak Agung Ngurah Anantasika; Made Darmayasa; I Gde Sastra Winata
Indonesian Journal of Obstetrics & Gynecology Science Volume 5 Nomor 2 September 2022
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v5n2.399

Abstract

Abstrak Tujuan: Untuk mengetahui ekspresi enzim 1-alfa-hidroksilase (CYP27B1) pada plasenta yang rendah sebagai faktor risiko terjadinya preeklamsia (PE) berat.Metode: Penelitian ini merupakan studi kasus-kontrol yang tak berpasangan, dengan total sampel 44 kasus dan kontrol. Sampel berupa plasenta yang diproses secara imunohistokimia, untuk melihat ekspresi enzim berdasarkan histoscore kumulatif (H-score) sebagai ekspresi rendah (H-score <200) atau ekspresi tinggi (H-score >200). Regresi logistik ganda digunakan untuk memperkirakan rasio odds yang disesuaikan (OR) dengan interval kepercayaan 95% (95% CI).Hasil: Ekspresi enzim 1alfa-hidroksilase plasenta yang rendah merupakan faktor risiko terjadinya PE berat sebesar sembilan kali lebih tinggi dibandingkan dengan ekspresi enzim 1-alfa-hidroksilase yang tinggi pada plasenta (OR 9,148; IK05% 2,072-40,386, p=0,002).Kesimpulan: Ekspresi rendah 1alfa-hidroksilase plasenta meningkatkan risiko terjadinya PE berat.Low Expression of 1 Alpha-Hydroxylase Enzyme in The Placenta as Arisk Factor for Preeclampsia with Severe FeaturesAbstractObjective: This study aims to determine the low expression of the 1-alpha-hydroxylase (CYP27B1) enzyme in the placenta as a risk factor for severe preeclampsia (PE).Methods: This study is an unpaired case-control study, with a total sample of 44 cases and controls. Samples were placentas that were immunohistochemically processed, to see enzyme expression based on the cumulative histoscore (H-score) as low expression (H-score <200) or high expression (H-score >200). Multiple logistic regression was used to estimate the adjusted odds ratio (OR) and 95% confidence interval (95% CI).Results: Low placental 1-alpha-hydroxylase expression was a risk factor for severe PE which was nine times higher than placental 1-alpha-hydroxylase expression (OR 9,148; 05% CI 2.072-40,386, p=0.002).Conclusions: Low placental 1alpha-hydroxylase expression increases the risk of severe PE.Key words: 1aplha-hydroxylase, expression, placenta, risk factor, severe preeclampsia
Evaluation of Abortion Measures in Government Regulation No. 28 of 2024 on The Right to Life of the Fetus From a Human Rights Perspective Florencia Desiree; I Gusti Ayu Putri Kartika; I Gede Sastra Winata; Piers Andreas Noak
Jurnal Syntax Transformation Vol 5 No 11 (2024): Jurnal Syntax Transformation
Publisher : CV. Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jst.v5i11.1023

Abstract

Indonesia has legalized abortion under certain conditions, such as pregnancy resulting from rape, through Government Regulation No. 28/2004. This policy has sparked heated debate because it contradicts the principle of protecting the right to life of the fetus. This study aims to provide a complex overview of the issue of abortion in Indonesia and its implications for human rights. The method used is normative legal research. This research is conducted by examining library materials or secondary data. The two approaches used are a statutory approach related to the legal issue of abortion and a conceptual approach to examine the medical legal understanding of abortion due to rape. Cases of sexual violence and rape in Indonesia are still high. In 2023, Komnas Perempuan recorded 2,078 cases of sexual violence, of which 143 were rapes. Abortion, in this context, is often used as a solution to address unwanted pregnancies. This research shows that while Government Regulation No. 28 of 2024 provides legitimacy to abortion, it is still contrary to the right to life of the fetus guaranteed by law. While abortion is considered a violation of the right to life, this policy is also considered a protection for women victims of sexual violence. Despite arguments to protect women's rights, the right to life of the fetus as a non-derogable right should not be ignored. Therefore, there needs to be a review of this regulation to ensure that all human rights, including the right to life of the fetus, are optimally protected.
Business Strategy for Hospital A (RSIA) Denpasar City with Business Model Canvas (BMC) Florencia Desiree; Erliany Syaodih; Budi Santoso
Jurnal Syntax Transformation Vol 5 No 12 (2024): Jurnal Syntax Transformation
Publisher : CV. Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jst.v5i12.1034

Abstract

The role of RSIA is less to provide real benefits to the community and has the potential to go bankrupt if there is no improvement in management. The indicators can be seen from the decline in visitation rates by 10% in 2022 and 5% in 2023, high employee turnover, hospital image through Google Reviews resulting in low average scores, and complaints on various services provided by the hospital. This study aims to map Hospital A's business model using the business model canvas so that the strengths, weaknesses, opportunities, and threats that could potentially harm the hospital can be identified. Data collection was conducted using interviews with triangulation techniques to key informants, comparison informants, and expert informants. The research approach is positivism or qualitative, which emphasizes meaning. The findings obtained are that Hospital A's market segmentation is the lower middle class with the application of vertical growth; in the value propositions block there are shortcomings such as no new services and technology, lack of communication, poor service, interior and exterior design using and needing renewal, and inadequate facilities, but has advantages in terms of price and cleanliness; in the channel block, strategic location but does not have good visibility; in the customer relationship block, there is different service treatment between room classes; hospital revenue streams from usage fees and brokerage fees; physical resources of employees are inadequate with untimely salary payments; in the key partnership block, the hospital collaborates with midwives and clinics.
Total Quality Management di Rumah Sakit: Tinjauan Literatur tentang Metodologi dan Pendekatan Terkait Widjanarko, Hendrawan; Tajuddin, Mohammad; Cahayani, Nadia Brigita; Desiree, Florencia; Rahayuningrum, Dessy Putri; Alexangela, Joanne Switasanny; Panjaitan, Sally Ester Rohana; Veranita, Mira
Manajemen Pelayanan Kesehatan Vol. 1 No. 2 (2024): April
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/mpk.v1i2.2945

Abstract

Tujuan dari penelitian ini adalah untuk menilai metode dari Total Quality Managemet (TQM) sebagai sistem manajemen kualitas yang berfokus pada pelanggan guna perbaikan yang berkesinambungan kaitannya dengan Rumah Sakit. Penelitian ini menggunakan metode tinjauan literatur untuk menggali berbagai sumber akademis dan praktis yang membahas tentang penerapan TQM di Rumah Sakit. Hasil dari penelitian ini diharapkan dapat menjadi tambahan wawasan yang lebih beragam dan dalam tentang aspek-aspek penting yang diharapkan dapat diterapkan di Rumah Sakit sehingga dapat meningkatkan kepuasan pasien melalui kualitas pelayan yang lebih baik.
Co-Authors Alexangela, Joanne Switasanny Anak Agung Ngurah Anantasika Budi Santoso Cahayani, Nadia Brigita Erliany Syaodih I Gde Sastra Winata I Gusti Ayu Putri Kartika, I Gusti Ayu I Made Darmayasa I Wayan Artana Putra I Wayan Megadhana Panjaitan, Sally Ester Rohana Piers Andreas Noak Rahayuningrum, Dessy Putri tajuddin, mohammad Veranita, Mira Widjanarko, Hendrawan