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All Journal Medicina E-Jurnal Medika Udayana Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) ISM (Intisari Sains Medis) : Jurnal Kedokteran Journal of Global Pharma Technology IJRETINA - International Journal of Retina Ophthalmologica Indonesiana
I Wayan Gede Jayanegara
Department Of Ophthalmology, Universitas Udayana, Bali, Indonesia
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Health Professions Medicine & Pharmacology Public Health

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Prevalence and Risk Factors of Senile Cataract in Balinese Population Age 50 Years Old or Older Anak Agung Mas Putrawati Triningrat; Putu Adhi Surya Pradana; Ariesanti Tri Handayani; Gde Ngurah Indraguna Pinatih; Made Agus Kusumadjaja; Wayan Gede Jayanegara
Journal of Global Pharma Technology Volume 10 Issue 07: (2018) July 2018
Publisher : Journal of Global Pharma Technology

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Abstract

Objective: Cataract is the leading cause of blindness in the world with increasing trend both in prevalence and incidence. Surgery is the only definitive treatment for cataract but often unaffordable for society in developing countries. The incidence of cataract could be prevented by understanding its risk factors and formulate health programs according to them. The purpose of this study was to assess the prevalence and risk factors of senile cataract among 50 years old or older Balinese population. Method: The population-based cross-sectional study was conducted from September 2015 until July 2016 in Bali province. The variable’s data were obtained through direct examination and interview. Poisson regression analysis was used to assess the definitive correlation between risk factors and cataract. A p-value <0.05 or value which falls within 95% confidence interval were considered significant. Result: 550 subjects were enrolled during the study. The number of cataracts found in this study was 231 (42%). According to the analyses, cataract was significantly associated with older age (PR: 3.05; p=0.001), low educational level (PR: 2.18; p=0.04), diabetes (PR: 2.96; p=0.001), and the rate of ultraviolet exposure (PR: 1.92; p=0,002). Conclusion: The prevalence of cataract among 50 years old or older in Balinese population was 42%. Older age, low education, diabetes mellitus, and ultraviolet exposure were found to be significant and independent risk factors for cataract in 50 years old or older Balinese population.Keywords: Cataract, Prevalence, Risk factor.
Emerging Challenges of Acute Bilateral Diabetic Cataract in Pediatric: Insight to Early Detection and Management– A Case Report Valentina, Clara; Sutyawan, I Wayan Eka; Surasmiati, Ni Made Ayu; Kusumadjadja, I Made Agus; I Wayan Gede Jayanegara
Majalah Oftalmologi Indonesia Vol 51 No 2 (2025): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v51i2.101671

Abstract

Purpose: To report rare case of acute bilateral cataract in pediatric with Type 1 Diabetes Mellitus as ocular complication despite of good glycaemic controls and its management. Methods: A 17-year-old male patient complained of blurry vision and glare in both eyes(BE) since 3 months in newly diagnosed T1DM (HbA1c 10% --> now 6.3%). Visual Acuity (VA) was 6/45PH6/21f2, with correction S-1.50 advancing to 6/18 in BE. Slitlamp examination of BE revealed lens opacity (P3),central position, 3mm in diameter, retinometri 0.32. Posterior segment evaluation and intraocular pressure (IOP) were within normal limits. Right eye (RE) was underwent lensectomy and IOL insertion under GA. Results:  Postoperative RE with final VA of 6/18 PHNI and IOP of 43 mmHg. Patient was given antiinflammation eyedrops, oral and topical antiglaucoma, and received controlled final IOP of 8mmHg within 3 days and remain stable until now without antiglaucoma. Result was satisfying despite of uncomplicated secondary glaucoma as short-term complication that resolved with therapy. Evaluation and close monitoring postoperatively is needed and play significant role in visual outcome. Conclusions: Early detection for ocular complication in DM is needed as cataract genesis process still progressing despite of good glycaemic control. Ocular manifestation may present as early sign of undiagnosed T1DM or as its complications. Comprehensive and holistic multidicipline treatment, glycaemic control,  and routine evaluation is essential and play significant role in the success of metabolic cataract therapy and progression of microvascular complications due to DM. Lensectomy + IOL implantation still the mainstay therapy in pediatric cataract.  Awareness play vital role as it possibly cause decreased vision and or amblyopia, leading to blindness.  
The Association Between Vitreous Vascular Endothelial Growth Factor Levels with Visual Acuity Before and After Pars Plana Vitrectomy in Proliferative Diabetic Retinopathy Noviantari, I Gusti Agung Ratna; Suryathi, Ni Made Ari; Triningrat, A.A. Mas Putrawati; Widiana, I Gde Raka; Andayani, Ari; Jayanegara, I Wayan Gede; Pantjawati, Ni Luh Diah
International Journal of Retina Vol 7 No 2 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss002.257

Abstract

Introduction: Vascular endothelial growth factor (VEGF) plays a crucial role in the development of proliferative diabetic retinopathy. Elevated levels of VEGF in the vitreous have been found to be associated with the severity of ischemia and neovascularization, which can lead to a decline in visual acuity. This study aims to determine the association between vitreous VEGF levels and improvement in visual acuity before and after PPV in PDR patients. Methods: This research is an analytic observational study with a pre-post single group design. The subjects of this study were all PDR patients who received PPV therapy at three hospital in Bali Province, Indonesia. Consecutive sampling method were conducted. The independent variable is vitreous VEGF, whilst pre and post-PPV visual acuity is the outcomes. We performed mean comparison and multivariable statistical test using IBM SPSS version 25. Result: 45 people were included in this study. Improvement in visual acuity after PPV compared to before PPV with an average improvement of 0.54 logMAR (p=0.001). Based on the ANCOVA multivariate analysis, factors affecting visual acuity improvement after PPV were preoperative vision (p<0.001), postoperative vision (p<0.001), HbA1c level (p=0.036), and DM duration (p=0.024). There was no association between high vitreous VEGF levels and visual acuity improvement (PR=0.95; 95% CI=0.55-1.63;p=0.841). Conclusion: This study concluded that there is an association between PPV and visual acuity improvement. However, clinicians should be aware of several confounding factors that affect visual acuity improvement, including pre-PPV visual acuity, post-PPV visual acuity, duration of DM, and HbA1c level. There is no relationship between vitreous VEGF and visual acuity before and after PPV in PDR, but it is necessary to keep good records of lens status and intraocular pressure status. Further research is needed and the research time is extended to evaluate a better visual outcome.
BARRAGE LASER PHOTOCOAGULATION IN HIGH-MYOPIC PATIENT WITH SYMPTOMATIC RETINAL TEARS BEFORE PHACOEMULSIFICATION: A CASE REPORT: Poster Presentation - Case Report - Ophthalmologist Budhiastra, I Putu; Tridiyoga, Komang Putra; Jayanegara, I wayan Gede; Suryathi, Ni Made Ari; Andayani, Ari; Pitanatri, Nyoman Brahmani
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/zdtpyp85

Abstract

Introduction : Retinal tears can be present in up to 2.4% of cases of lattice degeneration, which is considered an important risk of retinal detachment in a high-myopic patient. Laser photocoagulation has been shown to reduce the risks of retinal detachment before phacoemulsification thus improve in the visual outcome. We report a case of a high myopic patient with symptomatic retinal tears who underwent phacoemulsification that was treated prophylactically with barrage laser photocoagulation. Case Illustration : A 43 years-old female with a history of high myopia complained of flashes and floaters on both eyes. She had high myopia measuring -13.0 dioptres and -28.0 dioptres in the right and left eyes respectively. Unaided visual acuity was 2/60 in both eyes. Fundus examination showed lattice degenerations with a small tear found on both eyes with no retinal detachments. She was treated with a barrage laser on both eyes followed by phacoemulsification. On the last follow-up, the retina remained stable and the visual acuity was significantly improved with no development of macular edema or retinal detachment in both eyes. Discussion : Although most cases of lattice degeneration do not need intervention, some present a risk of retinal detachment. Barrage laser photocoagulation may have a place in high myopic patient lattice degeneration with symptomatic retinal tears to maintain retinal stability and to obtain the optimal outcome after phacoemulsification. Conclusion : Barrage laser photocoagulation is beneficial as a prophylactic treatment of symptomatic retinal tears before phacoemulsification in high-myopic patients.
Co-Authors Anak Agung Ayu Githasari Dewi Anak Agung Ayu Sukartini Djelantik Anak Agung Mas Putrawati T2 Anak Agung Mas Putrawati Triningrat Angelo Doniho Anthea Casey Ari Andayani Ariesanti Tri Handayani, Ariesanti Tri Bobby Kristianto Gde Ngurah Idraguna Pinatih Giovani Faustine I Gde Raka Widiana I Gusti Ayu Made Juliari I Gusti Ayu Ratna Suryaningrum I Putu Budhiastra, I Putu I Wayan Eka Sutyawan Ida Bagus Putra Manuaba Kusumadjadja, I Made Agus Made Agus Kusumadjaja Maria Septiana Parmonang Aroean Ni Made Ari Suryathi Ni Made Ayu Surasmiati Ni Made Suryanadi NLP Wistya Eka Mahadewi Noviantari, I Gusti Agung Ratna Nyoman Astri Dewi Sanjiwani Pantjawati, Ni Luh Diah Pitanatri, Nyoman Brahmani Putu Adhi Surya Pradana Putu Budhiastra Siska Siska Takarai Stacia Manggala Sutyawan, I Wayan Eka Tridiyoga, Komang Putra Triningrat, A.A. Mas Putrawati Valentina, Clara Yovita Govert