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Tannin Analysis of Red Roselle Petals (Hibiscus Sabdariffa, L.) using Permanganometry Method Anita Agustina Styawan; Aristhasari Putri; Refida Ramadhani Nur Cholifa
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (159.316 KB) | DOI: 10.53017/ujas.31

Abstract

Red roselle (Hibiscus sabdariffa L.) is a plant that can be used by the community as traditional medicine. Rosella flower petals contains protein, fat, minerals, alkaloids, flavonoids, and tannins. Red rosella is effective in preventing vertigo, antihypertension, antidiabetic, anticancer, and antioxidants. Tannins are known as one of the active ingredients contained in the petals of red rosella flowers. Tannins are polyphenolic protein. This study aims to determine the levels of tannin in the extract of red rosella flower petals using permanganometry titration. The research method used was observational. This study used a sample of red roselle flower petals. The sample was tested qualitatively using FeCl3 1%. Analyzed quantitatively using permanganometry titration. The results showed that qualitatively the positive sample contained tannins which was marked by a change in color to dark blue dark. Quantitatively the sample was titrated with KMnO4, the tannin content in red roselle flower petals was 13,73 % b/b.
Formulasi Sirup Ekstrak Temu Mangga (Curcuma mangga Val) Dengan Variasi Konsentrasi Sorbitol Dan CMC-Na Nurul Hidayati; Aristhasari Putri; Shefia Nur Rohmah
CERATA Jurnal Ilmu Farmasi Vol 14 No 1 (2023)
Publisher : UNIVRSITAS MUHAMMADIYAH KLATEN

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Temu mangga (Curcuma mangga Val) merupakan salah satu tanaman yang dapat menurunkan kadar glukosa dalam darah. Tanaman ini memiliki ciri khas aroma rimpang yang spesifik seperti aroma khas mangga segar, rasa yang manis tapi sedikit pahit. Dalam pemanfaatannya untuk menghilangkan rasa pahit dari temu mangga, maka dibuat dalam bentuk sirup. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi sorbitol dan CMC-Na terhadap sifat fisik sediaan sirup ekstrak temu mangga serta untuk mengetahui variasi konsentrasi sorbitol dan CMC-Na yang menghasilkan sifat fisik sirup yang baik. Temu mangga diekstraksi menggunakan metode maserasi dengan pelarut etanol 96%. Sirup temu manga diformulasikan sebanyak 3 formula dengan perbandingan variasi konsentrasi sorbitol: CMC Na, Formula I 20% : 1,00%, Formula II 27,5% : 1,125%, Formula III 35% : 1,25%. Sirup yang dihasilkan kemudian dilakukan pengujian sifat fisik meliputi uji organoleptis, uji homogenitas, uji pH, uji viskositas, dan uji waktu tuang. Hasil penelitian menunjukkan sirup ekstrak temu mangga dengan variasi konsentrasi sorbitol dan CMC-Na mempengaruhi sifat fisik sirup. Pada Formula II dengan konsentrasi sorbitol 27,5% dan CMC-Na 1,125% menghasilkan rasa manis, warna oranye, konsistensi sedikit kental, aroma khas temu mangga, jernih, homogen, pH 4,83 ± 0,05, viskositas 2,30 ± 0,10, waktu tuang 2,58 ± 0,06.
Gambaran Tingkat Pengetahuan Obat Antihipertensi Di Desa Kujon Kecamatan Ceper Kabupaten Klaten Aristhasari Putri; Avanilla Fany Septyasari; Maherawati Noni; Rheni Haryanti
CERATA Jurnal Ilmu Farmasi Vol 14 No 1 (2023)
Publisher : UNIVRSITAS MUHAMMADIYAH KLATEN

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hipertensi merupakan salah satu penyebab terjadinya penyakit kardiovaskuler yang dapat menyebabkan kematian terbesar di Indonesia. Pengetahuan pasien terhadap obat antihipertensi sangat mempengaruhi pemahaman pasien sehingga menyebabkan tercapainya keberhasilan terapi. Tujuan dari penelitian ini adalah untuk mengetahui gambaran pengetahuan pasien terhadap obat antihipertensi di Desa Kujon, Ceper, Klaten. Penelitian ini merupakan penelitian deskriptif observasional, dengan teknik pengambilan data secara purposive sampling pada pasien hipertensi yang ada di Desa Kujon, Ceper, Klaten didapatkan 57 responden. Responden penelitian menerima kuisioner kemudian kuisioner tersebut dinilai, hasilnya merupakan persentase pengetahuan. Hasil penelitian menunjukkan bahwa tingkat pengetahuan responden di Desa Kujon, Ceper, Klaten terhadap hipertensi, 80,7% kategori baik, 14,04% kategori cukup; dan 5,26% kategori kurang.
Tannin Analysis of Red Roselle Petals (Hibiscus Sabdariffa, L.) using Permanganometry Method Anita Agustina Styawan; Aristhasari Putri; Refida Ramadhani Nur Cholifa
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujas.31

Abstract

Red roselle (Hibiscus sabdariffa L.) is a plant that can be used by the community as traditional medicine. Rosella flower petals contains protein, fat, minerals, alkaloids, flavonoids, and tannins. Red rosella is effective in preventing vertigo, antihypertension, antidiabetic, anticancer, and antioxidants. Tannins are known as one of the active ingredients contained in the petals of red rosella flowers. Tannins are polyphenolic protein. This study aims to determine the levels of tannin in the extract of red rosella flower petals using permanganometry titration. The research method used was observational. This study used a sample of red roselle flower petals. The sample was tested qualitatively using FeCl3 1%. Analyzed quantitatively using permanganometry titration. The results showed that qualitatively the positive sample contained tannins which was marked by a change in color to dark blue dark. Quantitatively the sample was titrated with KMnO4, the tannin content in red roselle flower petals was 13,73 % b/b.
Formulasi Sirup Ekstrak Temu Mangga (Curcuma mangga Val) Dengan Variasi Konsentrasi Sorbitol Dan CMC-Na Nurul Hidayati; Aristhasari Putri; Shefia Nur Rohmah
CERATA Jurnal Ilmu Farmasi Vol 14 No 1 (2023): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v14i1.760

Abstract

Temu mangga (Curcuma mangga Val) merupakan salah satu tanaman yang dapat menurunkan kadar glukosa dalam darah. Tanaman ini memiliki ciri khas aroma rimpang yang spesifik seperti aroma khas mangga segar, rasa yang manis tapi sedikit pahit. Dalam pemanfaatannya untuk menghilangkan rasa pahit dari temu mangga, maka dibuat dalam bentuk sirup. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi sorbitol dan CMC-Na terhadap sifat fisik sediaan sirup ekstrak temu mangga serta untuk mengetahui variasi konsentrasi sorbitol dan CMC-Na yang menghasilkan sifat fisik sirup yang baik. Temu mangga diekstraksi menggunakan metode maserasi dengan pelarut etanol 96%. Sirup temu manga diformulasikan sebanyak 3 formula dengan perbandingan variasi konsentrasi sorbitol: CMC Na, Formula I 20% : 1,00%, Formula II 27,5% : 1,125%, Formula III 35% : 1,25%. Sirup yang dihasilkan kemudian dilakukan pengujian sifat fisik meliputi uji organoleptis, uji homogenitas, uji pH, uji viskositas, dan uji waktu tuang. Hasil penelitian menunjukkan sirup ekstrak temu mangga dengan variasi konsentrasi sorbitol dan CMC-Na mempengaruhi sifat fisik sirup. Pada Formula II dengan konsentrasi sorbitol 27,5% dan CMC-Na 1,125% menghasilkan rasa manis, warna oranye, konsistensi sedikit kental, aroma khas temu mangga, jernih, homogen, pH 4,83 ± 0,05, viskositas 2,30 ± 0,10, waktu tuang 2,58 ± 0,06.
Gambaran Tingkat Pengetahuan Obat Antihipertensi Di Desa Kujon Kecamatan Ceper Kabupaten Klaten Aristhasari Putri; Avanilla Fany Septyasari; Maherawati Noni; Rheni Haryanti
CERATA Jurnal Ilmu Farmasi Vol 14 No 1 (2023): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v14i1.761

Abstract

Hipertensi merupakan salah satu penyebab terjadinya penyakit kardiovaskuler yang dapat menyebabkan kematian terbesar di Indonesia. Pengetahuan pasien terhadap obat antihipertensi sangat mempengaruhi pemahaman pasien sehingga menyebabkan tercapainya keberhasilan terapi. Tujuan dari penelitian ini adalah untuk mengetahui gambaran pengetahuan pasien terhadap obat antihipertensi di Desa Kujon, Ceper, Klaten. Penelitian ini merupakan penelitian deskriptif observasional, dengan teknik pengambilan data secara purposive sampling pada pasien hipertensi yang ada di Desa Kujon, Ceper, Klaten didapatkan 57 responden. Responden penelitian menerima kuisioner kemudian kuisioner tersebut dinilai, hasilnya merupakan persentase pengetahuan. Hasil penelitian menunjukkan bahwa tingkat pengetahuan responden di Desa Kujon, Ceper, Klaten terhadap hipertensi, 80,7% kategori baik, 14,04% kategori cukup; dan 5,26% kategori kurang.
Gambaran Pengetahuan terhadap Penggunaan Obat Tanpa Resep di Desa Karangduren Kecamatan Kebonarum Kabupaten Klaten Septyasari, Avanilla Fany; Putri, Aristhasari; Nurhaini, Rahmi; Hastikanuari, Anis Anggiara
CERATA Jurnal Ilmu Farmasi Vol 15 No 1 (2024): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v15i1.1077

Abstract

Self-medication is an attempt to treat a condition or complaint based on self-diagnosed symptoms. The drugs used are non-prescription drugs, such as over-the-counter (OTC) drugs. Self-medication is one of the causes of medication errors. One of the factors in the occurrence of problems in self-medication is the lack of knowledge and understanding of the community regarding drugs and their indications. The purpose of this study was to determine the level of knowledge of the use of non-prescription drugs in the community of Karangduren Village, Kebonarum District, Klaten Regency. This research is an observational descriptive research. The sampling technique used simple random sampling method, and a questionnaire containing 15 questions including the name and content of the drug, drug efficacy, drug dosage, drug administration, and drug side effects. There were 67 respondents involved in this study. The results showed that most respondents (50.7%) had a good level of knowledge in using non-prescription drugs.
Comparison of Caffeine Compound Levels in Brewed and Boiled Oolong Tea Leaves (Camellia sinensis (L.) Kuntze) Based on Different Processing Methods Styawan, Anita Agustina; Aristhasari Putri; Ocha Ardela Fitria Kresnaya
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 8 No.1 (2025)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v8i1.54457

Abstract

Introduction: Tea contains many compounds that are beneficial for the body, namely caffeine. The process of brewing tea with a time and temperature that is not optimal can affect the caffeine content in it. And the brewing process by heating can widen the distance between the molecules in the tea. The higher the temperature and the longer the brewing time, the higher the caffeine content.. Aims: This study aims to analyze the caffeine content of brewed and boiled oolong tea, then compare the caffeine content of oolong tea with brewing (without heating) and boiled (with heating) processes. Methods: The research method used is experimental. This study used dried samples of oolong tea leaves (Camellia sinensis (L.) Kuntze). Quantitative analysis using UV-Vis Spectrophotometry. Result: Quantitatively, the caffeine content in brewed oolong tea was 3.522% w/w and the caffeine content in boiled oolong tea was 4.001% w/w. The conclusion of this study is that there is no significant difference in caffeine levels in brewed and boiled oolong tea with a significant value of P> 0.05.
Formulasi dan Uji Sifat Fisik Krim Ekstrak Biji Lengkeng (Euphoria longan (Lour) Steud) Muchson Arrosyid; Hardhani, Salsabila Nur; Mustofa, Choiril Hana; Putri, Aristhasari; Septyasari, Avanilla Fany
CERATA Jurnal Ilmu Farmasi Vol 16 No 1 (2025): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v16i1.1673

Abstract

Lengkeng termasuk kedalam tumbuhan tropis yang memiliki kandungan kimia yang salah satunya berfungsi sebagai antihiperpigmentasi kulit. Bagian tumbuhan yang belum banyak dimanfaatkan adalah bagian biji. Tujuan penelitian ini yaitu untuk mengetahui sifat fisik formula krim biji lengkeng dengan variasi konsentrasi 1%, 2%, dan 3%. Metode pengujian yang dilakukan meliputi uji organoleptis, uji tipe krim, uji pH, uji homogenitas, uji daya sebar, dan uji viskositas. Hasil menunjukkan bahwa ketiga formula ekstrak biji lengkeng menghasilkan uji organoleptik dengan hasil krim kental berwarna coklat, uji pH yang memenuhi standar, uji tipe emulsi M/A, uji homogenitas krim homogen, uji daya sebar memenuhi standar, dan uji viskositas juga memenuhi standar.
Patient adherence and factors associated with short-term oral antibiotic use for acute respiratory infections (ISPA) in Wedi primary health care Putri, Aristhasari; Septyasari, Avanilla Fany; Ridhwan, Adib Muhammad
Borobudur Pharmacy Review Vol. 5 No. 2 (2025): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i2.14513

Abstract

Upper respiratory tract infection (URTI) is a common illness in Indonesia caused by microorganisms, caused by microorganisms that affect the upper respiratory tract. Short-term antibiotic therapy is frequently prescribed, but many patients do not adhere to this treatment. Non-compliance often occurs because patients feel better, forget to take their medication, or do not follow the prescribed regimen properly. This can lead to poor clinical outcomes and an increased risk of bacterial resistance. This study was conducted to to assess the level of adherence and contributing factor among URTI patients to short-term oral antibiotic therapy. A cross-sectional research design was employed, utilizing a structured questionnaire for data collection. The sampling method applied was purposive sampling, which included a cohort of 31 patients with URTI who were prescribed short term antibiotics. The results showed that 77.4% of respondents were compliant, while 22.6% were non-compliant. Factors that significantly associated with adherence included educational level and occupation (p < 0.05), while age did not show a significant relationship (p > 0.05). Another factors influencing non-adherence included inadequate information provided by healthcare professionals, busy schedules, premature discontinuation of therapy due to perceived recovery, lack of family support, and difficulty swallowing medication. Pharmacists can play a significant role in improving compliance by providing clear information and utilizing reminder tools to assist patients in taking their medication as prescribed.