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Antibacterial Activity Test of Meniran Herb Extract (Phyllanthus Niruri L.) against Staphylococcus Epidermidis and Klebsiella Pneumoniae Nahrul Hasan Nahrul; Aprilya Sri Rachmayanti; Eem Masaenah
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.927

Abstract

An antibacterial test of meniran herb extract (Phyllanthus niruri L.) against Staphylococcus epidermidis and Klebsiella pneumoniae has been carried out. Meniran herb powder was screened for phytochemicals to assess the secondary metabolites contained in it, then meniran herbs were extracted using the soxhletation method in stages with various solvents (n-hexane, ethyl acetate, and 70% ethanol). The disc diffusion method was used to test the inhibition zone diameter of n-hexane extract, ethyl acetate extract, and ethanol extract against Staphylococcus epidermidis and Klebsiella pneumoniae. Meniran herb extract was diluted with a concentration series using dimethylsulfoxide. Meniran herb extracts from the three types showed the best inhibition zone diameter when tested for minimum inhibitory concentration (MIC) by the solid dilution method. The results showed that meniran herb powder contained flavonoids, saponins, tannins, glycosides, and steroids/terpenoids. Antibacterial tests showed that ethyl acetate and 70% ethanol extracts had antibacterial activity only against Staphylococcus epidermidis. The antibacterial activity of the two meniran herb extracts had the largest inhibition zone diameter against Staphylococcus epidermidis at a concentration of 50%, which was 12,33 mm for the ethyl acetate extract and 16,00 mm for the ethanol extract. The MIC test of the ethanol extract of the meniran herb, which had the best antibacterial activity, found that at a concentration of 2,5% it was able to inhibit the growth of Staphylococcus epidermidis.
Hubungan Karakteristik Penderita Hipertensi dengan Tingkat Kepatuhan Minum Obat di RSUD Embung Fatimah Kota Batam Suci Fitriani Sammulia; Aprilya Sri Rachmayanti; Erna Chintia
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 1 No. 3 (2022): Juli 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v1i3.429

Abstract

Hypertension is one of the non-communicable diseases which is a problem in the health sector and is often found in primary health services. A person is said to suffer from hypertension when systolic blood pressure ≥ 140 mmHg and diastolic pressure ≥ 90 mmHg. The use of antihypertensive drugs alone is proven to be insufficient to produce long-term blood pressure control effects if it is not supported by adherence to the use of antihypertension. The high incidence of hypertension in the world, is influenced by two types of factors, namely factors that cannot be changed such as age, sex, and race. Furthermore, factors that can be changed include obesity, alcohol consumption, lack of exercise, excessive salt consumption, and smoking habits. The purpose of this study was to determine the relationship between the characteristics of hypertension sufferers with the level of adherence to take medication at Embung Fatimah District Hospital in Batam. This study used a cross-sectional descriptive study method using the MMAS-8 (Morisky Medication Adherence Scale) questionnaire. Respondents who were the subject of this study were suffering from hypertension at Embung Fatimah Regional Hospital in Batam. The sampling technique used is a simple random sampling technique with a total sample of 96 people. The results of this study generally showed that 36.5% of patients had high adherence to take hypertension medication while the remaining 13.5% of patients had moderate adherence and as many as 50% had high adherence. To support the success rate of hypertension treatment can be done with the presence of hypertension counseling so that adherence to taking medication for hypertension sufferers can increase.
Aktivitas Antibakteri Ekstrak Bronok (Acaudina molpadioides) terhadap Pertumbuhan Bakteri Staphylococcus aureus dan Escherichia coli: Antibacterial Activity of Bronok Extract (Acaudina molpadioides) against the Growth of Staphylococcus aureus and Escherichia coli Bacteria Suhaera Suhaera; Aprilya Sri Rachmayanti; Nadya Aoliyaninda
Jurnal Surya Medika (JSM) Vol. 8 No. 3 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i3.3599

Abstract

Bronok (Acaudina molpadioides) is a type of marine biota of the phylum Echinoderms class Holothuroidea that can empirically increase stamina and have positive effects on health. One of the infectious diseases such as diarrhea is caused by Escherichia coli and Staphylococcus aureus bacteria which are still a major problem in public health and have the potential to cause death. Most of these bacteria have developed resistance to antibiotics This study aims to determine the antibacterial activity of extracts of bronchus (Acaudina molpadioides) against the growth of Staphylococcus aureus and Escherichia coli bacteria. In addition, this study uses the disc diffusion method with concentrations of 25%, 50% and 75% with the sample used is bronchoconstriction extract. The results of the bland zone diameter showed that methanol extract was able to inhibit the growth of Staphylococcus aureus bacteria with an average diameter of 4.1 mm, 5.3 mm, and 5.8 mm, ethyl acetate extract which is 4.7 mm, 6.2 mm, and 15.2 mm. Methanol extract showed resistance to Escherichia coli bacteria with an average diameter of 3.7 mm, 4.5mm, and 5 mm. The results of the bronok extract study (Acaudina molpadioides) had antibacterial activity against Staphylococcus aureus bacteria in methanol and ethyl acetate extracts. Methanol extract has antibacterial activity against Escherichia coli bacteria. By looking at the inhibition zone of each solvent where the larger the inhibition zone, the stronger the antibacterial activity.
Optimization of HPMC as Gelling Agent in Gel Formula of Etanol Extract of Bangun-Bangun Leaves (Plectranthus amboinicus (Lour) Spreng) Suci Fitriani Sammulia; Aprilya Sri Rachmayanti; Joel Lam Parulian Tampubolon
Jurnal EduHealth Vol. 14 No. 01 (2023): Jurnal eduHealth, Periode Januari-Maret, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (217.498 KB)

Abstract

Hidroxy Propyl Methyl Cellulose (HPMC) is a semi synthetic cellulose derivative gelling agent and can form a clear and neutral gel and has a stable viscosity in the long run. This study aims to determine the concentration of how much HPMC can form ethanol extracts of bangun-bangun leaves (Plectranthus amboinicus (Lour) Spreng) and stability of gel extract preparations. This research is an experimental study, in which the ethanol extract gel formulation of bangun-bangun leaves (Plectranthus amboinicus (Lour) Spreng) was conducted, by varying the concentration of HPMC at concentrations of 3%, 4% and 5%. Bangun-bangun leaves extract obtained from the maceration process and formulated in gel form. Furthermore, physical properties were evaluated, which included tests of adhesion, dispersion, pH, and viscosity on the bangun-bangun leaves extract gel. The evaluation results are then presented in tabular form. The evaluation results are then presented in tabular form. The optimum formula of the bangun-bangun leaves extract gel is a formula that contains 4% HPMC. Based on the results of the study is known that the results of the evaluation of the physical properties can be said to be stable after 4 weeks of stronge.
Gambaran Pelaksanaan Penyimpanan Cara Distribusi Obat Yang Baik Dan Benar (CDOB) Di PBF BUMN Dan Non BUMN Kota Batam Aprilya Sri Rachmayanti; Mawarni Badar; Chintia Wulandari; Suci Fitriani Sammulia; Reny Haryani; Nahrul Hasan
The Journal General Health and Pharmaceutical Sciences Research Vol. 1 No. 2 (2023): June: The Journal General Health and Pharmaceutical Sciences Research
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/tjghpsr.v1i2.186

Abstract

Good Distribution Method (CDOB) is a method of distributing or dispensing drugs and/or medicinal substances that aims to ensure quality by quality requirements and intended use in a distribution channel. Actions related to drug distribution are the acquisition, storage, and distribution of drugs from manufacturers to consumers. The use of CDOB is expected to maintain the quality of drugs received by patients and ensure conformity with the quality of drugs from the pharmaceutical industry. The research aims to find out the results of the implementation of Good Medicine Distribution Methods at PBF Enseval Putera Megatrading Tbk and PBF Kimia Farma Trading Distribution. This research is a type of observational research (evaluative non-experimental) that is descriptive in nature to get a realistic and objective picture of a condition that is currently occurring in a community group which contains questions addressed to Pharmaceutical Personnel on duty at PBF Kimia Farma and PBF Enseval Putera Megatrading Tbk Batam City. The results of research on PBF Enseval Putera Megatrading Tbk, and PBF Kimia Farma Trading Distribution, namely the score obtained from the evaluation results of CDOB implementation at PBF Enseval Putera Megatrading Tbk is in the very good category, namely with a percentage of (99%) and the score obtained from the evaluation results of CDOB implementation in PBF Kimia Farma Trading Distribution is in the very good category, namely with a percentage of (99%). Based on the research results, the description of CDOB implementation at PBF Enseval Putera Megatrading Tbk and Kimia Farma Trading Distribution is in the very good category (99%).
Upaya Pencegahan Ketergantungan NAPZA Pada Generasi Muda Di Kelurahan Bulang Lintang Suci Fitriani; Aprilya Sri Rachmayanti; Habibie Habibie
KREATIF: Jurnal Pengabdian Masyarakat Nusantara Vol. 1 No. 3 (2021): September : Jurnal Pengabdian Masyarakat Nusantara
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/kreatif.v1i3.2957

Abstract

NAPZA is an abbreviation of narcotics, psychotropics and addictive substances. Drug abuse is not only dangerous and detrimental to the family, but has broad social impacts. The Prevention, Eradication of Drug Abuse and Illegal Trafficking (P4GN) program needs to be carried out by focusing on prevention activities as an effort to make workers have the mindset, attitude and skills to reject drug abuse and illicit trafficking. It is hoped that this research can illustrate the effectiveness of the P4GN program outreach in preventing drug abuse among workers. The research was conducted in 2014 and carried out on 50 loading and unloading workers at Trisakti Port, Banjarmasin. The research instrument used a questionnaire and educational media. Before the extension is carried out, a pre-test and post-test are given after the extension to assess the effectiveness of the P4GN extension. The results of the analysis using the Wilcoxon test showed that there was a significant difference in knowledge between before the counseling and after the counseling was carried out. It is hoped that this research can increase the workforce's knowledge of drugs so that they can avoid drug abuse.
Pengabdian Kepada Masyarakat Melalui Penyuluhan Perilaku Hidup Sehat Kota Batam Suhaera Suhaera; Ghalib Syukrillah Syahputra; Aprilya Sri Rachmayanti; Henny Rachdianti Tjahjono Suyarto
KREATIF: Jurnal Pengabdian Masyarakat Nusantara Vol. 1 No. 3 (2021): September : Jurnal Pengabdian Masyarakat Nusantara
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/kreatif.v1i3.2960

Abstract

Batam City faces health problems related to lifestyle, such as obesity, diabetes, hypertension and heart disease. This can be caused by unhealthy eating patterns, lack of physical activity, as well as smoking and alcohol consumption. Counseling about the importance of a healthy lifestyle is important to reduce morbidity and mortality due to this disease. Healthy Living Behavior Counseling in Batam City not only aims to increase people's knowledge about healthy eating patterns and the importance of exercise, but also to change their attitudes and behavior in daily practice. Through outreach that is held systematically and continuously, it is hoped that the people of Batam City can understand the positive impact they will experience by adopting a healthy lifestyle.