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PEMANFAATAN MINYAK BIJI LABU KUNING (CUCURBITA MOSCHATA DURCH) MENJADI SEDIAAN NANOEMULSI TOPIKAL SEBAGAI AGEN PENGEMBANGAN COSMETICAL ANTI AGING Rohani Panjaitan; Shibghatun Ni’mah; Romdhonah Romdhonah; Lily Annisa
Khazanah: Jurnal Mahasiswa Vol. VII, No. 2, Januari 2015
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol7.iss2.art5

Abstract

Kulit merupakan bagian tubuh paling luar yang berfungsi sebagai pelindung dan merupakan salah satu jalur ekskresi tubuh. Oleh karena itu, kulit sangat kerusakan pada sel-sel kulit. Kerusakan tersebut dapat menyebabkan kulit menjadi kusam dan dapat mempercepat penuaan serta berisiko terkena kanker kulit.Indonesia merupakan negara agraris yang sebagian besar perekonomiannya mengandalkan sektor pertanian. Ragam tanaman yang diproduksinya pun banyak mulai dari tanaman palawija, sayur-sayuran hingga buah-buahan, dan di antara beragam tanaman tersebut selain berfungsi untuk memenuhi bahan pangan juga dapat bermanfaat dalam pengembangan di bidang kesehatan.Aging merupakan suatu proses penuaan yang ditandai dengan penurunan energi seluler yang menurunkankemampuan sel untuk memperbaiki diri. Agen kimia seperti polutan, asap rokok, sinar matahari berlebih yang mengandung radikal bebas dari peroksida yang mengikat oksigen adalah faktor lingkungan yang dapat mempercepat penuaan atau yang dikenal dengan penuaan dini.Labu kuning atau Cucurbita moschata merupakan tanaman yang banyak dimanfaatkan sebagai bahan pangan. Pemanfaatan bijinya di Indonesia masih terbatas pada produksi kuaci biji labu sedangakan biji labu kuning ternyata memiliki beberapa senyawa yang sangat berpotensi sebagai antiaging. Diantaranya adalah asam lemak utama, vitamin E, karotenoid, asam amino, dan inhibitor tripsin. Senyawa-senyawa tersebut bermanfaat untuk menghambat peroksida menjadi radikal bebas, sebab radikal bebas tersebut dapat merusak membran sel yang dapat berakibat pada penyakit degeneratif dan kanker kulit.Penelitian ini dimaksudkan memanfaatkan minyak biji labu untuk dibuat dalam sediaan nanoemulsi dan mengetahui stabilitas sediaan nanoemulsi minyak biji labu tersebut. Penelitian ini akan dilakukan di laboratorium Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Islam Indonesia selama 3-4 bulan dengan evaluasi stabilitas fisik dari sediaan.
Effect of Levonorgestrel Implant on Lactation and Infant Growth: A Review: Review : Pengaruh Implan Levonorgestrel pada Laktasi dan Pertumbuhan Bayi Febrianti, Yosi; Hanifah, Suci; Febrian, M. Pandoman; Annisa, Lily; Azza, Lintang Prava; Mafruhah, Okti Ratna; Medisa, Dian; Sari, Chynthia Pradiftha
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.17045

Abstract

Background: Family Planning is a way to regulate the number of children born and the spacing of pregnancies through information, education, and the use of contraceptives. Postpartum contraception is important to obtain an optimal interpregnancy interval. Postpartum contraception should be initiated early; one of which is Long-Acting Reversible Contraception (LARC). Levonorgestrel can be used to prevent pregnancy because it interferes with ovulation, implantation, and fertilization. Objectives: This study aimed to assess the efficacy and effects of using levonorgestrel implants on breastfeeding and infant growth. Methods: Primary data were in the form of research papers obtained from PubMed®, and Google Scholar® published from the period 2010-2018. The keywords for the searches included: “levonorgestrel”, “levonorgestrel (LNG)-releasing implant”, “levonorgestrel on lactogenesis”, “levonorgestrel on infant growth”, and “levonorgestrel on breastfeeding”, which were used alone or in combination. Results: The 20 selected articles were reviewed based on five identified phrases. Levonorgestrel subdermal implants were shown to be a good choice for women who wanted effective contraception. When used by breastfeeding mothers, levonorgestrel subdermal implants affected neither infant growth (0-1 year of age) nor lactation duration. Conclusions: Levonorgestrel subdermal implants can be effective long-term contraception. These implants are safe for breastfeeding mothers and do not affect infant growth.
Profil dan Efektivitas Terapi Pasien Glaukoma Rawat Jalan di Rumah Sakit di Yogyakarta Annisa, Lily; Jasmine, Iqtafit Zachrofati; Violita, Nindhi Happy
Indonesian Journal of Medical and Pharmaceutical Science Vol. 4 No. 2 (2025)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v4i2.451

Abstract

Background: Glaukoma is one of the eye diseases that most often causes permanent blindness. The effectiveness of glaukoma therapy is generally assessed by the reduction of intraocular pressure and improvement of the patient's clinical condition. The research aims to examine the therapeutic profile and effectiveness of outpatient glaucoma patients in a hospital in Yogyakarta. Methods: This study is a descriptive observational study with a cross-sectional design. Data collection was carried out retrospectively through medical records of outpatients at hospitals in Yogyakarta in 2023-2024 with a purposive sampling method. Analysis of the relationship between treatment profiles and effectiveness was carried out using the Chi-square test. Results: In this study, patients with the use of antiglaukoma combination therapy regiments were more dominant (57.07%) with additional administration of supportive therapy of (71.73%). The combination of antiglaukoma groups of beta-blockers-prostaglandin analogs with the combination drug timolol-latanoprost was the most commonly administered drug (26.7%). Artificial tears (65.97%) are a supportive therapy often given in conjunction with antiglaukoma therapy. The analysis results showed there was no relationship between the therapy regiment (p = 0.41) or the type of therapy (p = 0.897) with the effectiveness of antiglaukoma drug therapy. Conclusion: Combination antiglaukoma therapy is given more often than monotherapy. The combination of timolol and latanoprost is the most commonly given regiment. The majority of patients received antiglaukoma along with supportive therapy. There was no relationship between the therapy regiment or the type of drug with the effectiveness of therapy.
PENGARUH KONTEN TIKTOK TERHADAP TINGKAT PENGETAHUAN TENTANG ANTIBIOTIK PADA MAHASISWA UNIVERSITAS ISLAM INDONESIA Novi Dwi Rugiarti; Lastri, Lastri; Annisa, Lily
Nusantara Hasana Journal Vol. 5 No. 5 (2025): Nusantara Hasana Journal, October 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i5.1724

Abstract

Antibiotic resistance is a global health issue largely caused by the misuse of antibiotics. Increasing public knowledge about rational antibiotic use is a key step in controlling antimicrobial resistance. This study aimed to determine the effect of educational content on the social media platform TikTok on students’ knowledge about antibiotics at Universitas Islam Indonesia. The research employed a pre-test–post-test design, with a 63-second educational video as the intervention. The study involved 351 students selected through accidental sampling. The research instrument was a questionnaire that had been tested for validity and reliability. The results showed a significant increase in the average knowledge score from 73.25% in the pre-test to 91.16% in the post-test (p < 0.05). These findings indicate that TikTok-based educational content effectively improves students’ understanding of appropriate antibiotic use. Social media can serve as an engaging and accessible platform for health education, especially among young people. Utilizing TikTok as a medium for health promotion is expected to support national efforts in preventing antimicrobial resistance in Indonesia.
AKSI APOTEKER MUDA: EDUKASI BIJAK ANTIBIOTIK BERBASIS PENILAIAN PENGETAHUAN DAN SIKAP MASYARAKAT Lily Annisa; Jihan Nur Nabila; Zhorifah Inas Salsabila; Rubin Adhi Kurniawan; Zhafira Azka Medina; Zulfadila Azzahra; Ihca Wulandari; Yuvina Seran; Himmah Niswannabila; Balqis Kasha Sirsaeba Suryadi
JMM (Jurnal Masyarakat Mandiri) Vol 10, No 4 (2026): Agustus
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v10i4.40264

Abstract

Abstrak: Peningkatan resistensi antibiotik secara global maupun di Indonesia menjadi ancaman yang serius. Kondisi ini menyebabkan infeksi dengan terapi antibiotik menjadi tidak efektif sehingga semakin sulit ditangani. Rendahnya pengetahuan masyarakat berkontribusi pada peningkatan kejadian resistensi. Pengetahuan memiliki peran penting dalam membentuk keyakinan dan sikap terhadap suatu perilaku, termasuk dalam penggunaan antibiotic. Program Studi Profesi Apoteker (PSPA) mengajak rekan apoteker muda untuk berperan dalam sebuah kegiatan pengabdian masyarakat yang bertujuan untuk meningkatkan pengetahuan dan sikap masyarakat terakit penggunaan antibiotik dan resistensi antibiotik. Kegiatan ini dilakukan disalah satu RT di desa yang berada di Provinsi Yogyakarta dengan target penyuluhan seluruh warga kategori dewasa yang bersedia mengikuti kegiatan penyuluhan. Kegiatan penyuluhan kepada masyakarat dilakukan dengan metode verbal dan visual menggunakan media leaflet dan poster, serta dievaluasi melalui hasil kuisioner pre-test post-test yang telah diuji validasi dan reliabilitasnya. Data dianalisis secara statistik menggunaakan software R dengan uji wilcoxon. Signed-Rank Test dan uji Paired T-Test dengan tingkat signifikansi 0,05. Hasil evaluasi secara statistik kepada 30 responden menujukkan terdapat perbedaan signifikan pengetahuan (p value <0,0001) dan sikap (p value <0,0041) masyarakat sebelum dan sesudah penyuluhan. Terdapat peningkatan nilai pengetahuan sebesar 22.76% dan nilai sikap sebanyak 6.72% dibandingkan nilai sebelum penyuluhan.Abstract: Increased antibiotic resistance globally also in Indonesia become seriously problem. This condition makes infections ineffective against antibiotic therapy, making them increasingly difficult to treat. Lack of public awareness contributes to the increase in resistance. Knowledge plays a crucial role in shaping beliefs and attitudes toward behavior, including antibiotic use. PSPA Universitas Islam Indonesia invited young pharmacists to participate in a community service activity aimed at improving public knowledge and attitudes regarding antibiotic use and antibiotic resistance. This activity was conducted in one neighborhood association in a village in Yogyakarta, targeting all adults who were willing to participate. The community outreach activity utilized verbal and visual methods, using leaflets and posters. It was evaluated through pre- and post-test questionnaires that had been validated and validated for reliability. Data were statistically analyzed using R software using the Wilcoxon test, Signed-rank test, and Paired T-Test with a significance level of 0.05. The results of a statistical evaluation of 30 respondents showed a significant difference in knowledge (p-value<0.0001) and attitudes (p-value<0.0041) between the community before and after the outreach program. There was a 22.76% increase in knowledge and 6.72% increase in attitudes compared to the pre-outreach program.