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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Indonesian Journal of Medical and Pharmaceutical Science
Lily Annisa, Lily
Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Islam Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Effect of Levonorgestrel Implant on Lactation and Infant Growth: A Review: Review : Pengaruh Implan Levonorgestrel pada Laktasi dan Pertumbuhan Bayi Febrianti, Yosi; Hanifah, Suci; Febrian, M. Pandoman; Annisa, Lily; Azza, Lintang Prava; Mafruhah, Okti Ratna; Medisa, Dian; Sari, Chynthia Pradiftha
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.17045

Abstract

Background: Family Planning is a way to regulate the number of children born and the spacing of pregnancies through information, education, and the use of contraceptives. Postpartum contraception is important to obtain an optimal interpregnancy interval. Postpartum contraception should be initiated early; one of which is Long-Acting Reversible Contraception (LARC). Levonorgestrel can be used to prevent pregnancy because it interferes with ovulation, implantation, and fertilization. Objectives: This study aimed to assess the efficacy and effects of using levonorgestrel implants on breastfeeding and infant growth. Methods: Primary data were in the form of research papers obtained from PubMed®, and Google Scholar® published from the period 2010-2018. The keywords for the searches included: “levonorgestrel”, “levonorgestrel (LNG)-releasing implant”, “levonorgestrel on lactogenesis”, “levonorgestrel on infant growth”, and “levonorgestrel on breastfeeding”, which were used alone or in combination. Results: The 20 selected articles were reviewed based on five identified phrases. Levonorgestrel subdermal implants were shown to be a good choice for women who wanted effective contraception. When used by breastfeeding mothers, levonorgestrel subdermal implants affected neither infant growth (0-1 year of age) nor lactation duration. Conclusions: Levonorgestrel subdermal implants can be effective long-term contraception. These implants are safe for breastfeeding mothers and do not affect infant growth.
Profil dan Efektivitas Terapi Pasien Glaukoma Rawat Jalan di Rumah Sakit di Yogyakarta Annisa, Lily; Jasmine, Iqtafit Zachrofati; Violita, Nindhi Happy
Indonesian Journal of Medical and Pharmaceutical Science Vol. 4 No. 2 (2025)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v4i2.451

Abstract

Background: Glaukoma is one of the eye diseases that most often causes permanent blindness. The effectiveness of glaukoma therapy is generally assessed by the reduction of intraocular pressure and improvement of the patient's clinical condition. The research aims to examine the therapeutic profile and effectiveness of outpatient glaucoma patients in a hospital in Yogyakarta. Methods: This study is a descriptive observational study with a cross-sectional design. Data collection was carried out retrospectively through medical records of outpatients at hospitals in Yogyakarta in 2023-2024 with a purposive sampling method. Analysis of the relationship between treatment profiles and effectiveness was carried out using the Chi-square test. Results: In this study, patients with the use of antiglaukoma combination therapy regiments were more dominant (57.07%) with additional administration of supportive therapy of (71.73%). The combination of antiglaukoma groups of beta-blockers-prostaglandin analogs with the combination drug timolol-latanoprost was the most commonly administered drug (26.7%). Artificial tears (65.97%) are a supportive therapy often given in conjunction with antiglaukoma therapy. The analysis results showed there was no relationship between the therapy regiment (p = 0.41) or the type of therapy (p = 0.897) with the effectiveness of antiglaukoma drug therapy. Conclusion: Combination antiglaukoma therapy is given more often than monotherapy. The combination of timolol and latanoprost is the most commonly given regiment. The majority of patients received antiglaukoma along with supportive therapy. There was no relationship between the therapy regiment or the type of drug with the effectiveness of therapy.
Co-Authors Azza, Lintang Prava Chynthia Pradiftha Sari, Chynthia Pradiftha Febrian, M. Pandoman Fita Rahmawati Jasmine, Iqtafit Zachrofati Mafruhah, Okti Ratna Medisa, Dian Mustafidah, Nasikhatul Suci Hanifah Violita, Nindhi Happy Yosi Febrianti, Yosi