Alqarama M. Thalib
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The use of teledentistry and Artificial Intelligence (AI) in dental and oral health services for the elderly in the era of the covid-19 pandemic: A systematic review Bahruddin Thalib; Rifaat Nurrahma; Asmawati; Alqarama M. Thalib; Mohammad NF. Taufik
Journal of Dentomaxillofacial Science Vol. 7 No. 3 (2022): (Available online: 1 December 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v7i3.1406

Abstract

Objective: This paper aims to determine the use of teledentistry and AI in the elderly to maintain the health of their oral cavity and teeth during the COVID-19 pandemic. Methods: Technology in dentistry today is developing very rapidly, improving the quality of dental and oral health services. During the pandemic, the elderly has concerns about Covid-19 contamination when they have to see a dentist. Their situation has led to discussions and efforts to use teledentistry and Artificial intelligence to facilitate services and care for the elderly during the pandemic. Results: Teledentistry is used as a medium for consultation, diagnosis, referral system, treatment, and follow-up. While Artificial Intelligence (AI) has been used in diagnostic, patient data management, restoration, and CAD/CAM-based denture manufacture, detecting periodontal disease, and dental radiology. Conclusion: Teledentistry and AI can be a promising alternative in dental and oral health services to reduce anxiety and fear of contamination with Covid-19. The technologies make it easier for health workers, especially dentists, to maintain and improve the quality of life of the elderly during the pandemic.
Marine sponges as potential inhibitors of oral squamous cell carcinoma: Spons laut sebagai penghambat potensial karsinoma sel skuamosa oral Asmawati; Bahruddin Thalib; Alqarama M. Thalib; Sitti Jahadiyah; Linda
Makassar Dental Journal Vol. 12 No. 3 (2023): Volume 12 Issue 3 Desember 2023
Publisher : Makassar Dental Journal PDGI Makassar

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Abstract

Ekstrak senyawa dari marine sponges mampu mencegah pertumbuhan sel kanker dengan cara mencegah perkembangbiakan sel ganas dengan menginduksi apoptosis melalui kondensasi kromatin atau fragmentasi DNA sehingga menghasilkan apoptosis sel kanker. Keadaan tersebut akhirnya memicu program kematian sel melalui peningkatan jalur apoptosis. Artikel ini dimaksudkan untuk mengetahui manfaat senyawa turunan marine sponges dalam menghambat perkembangan oral squamous cell carcinoma (OSCC). Beberapa senyawa bioaktif yang diproduksi dari marine sponges seperti manoalide, stellettin B, methanol extract T.swinhoi, ilimaquinon, stigmasterol meningkatkan stres oksidatif, menghasilkan stres oksidatif N-acetylcysteine, Mito-Tempo dan ZVAD sel kanker mulut, efek antiproliferasi pada sel kanker mulut, stres oksidatif mengatur peningkatan subG1, menghambat aktivasi caspase 3 dan 3/7, memicu stres ER yang lebih tinggi, sitotoksik yang kuat pada sel KB/C152 dibandingkan dengan sel Jurkat/E6-1, aktivasi mitogen-activated protein kinase yang berperan terhadap apoptosis dan kerusakan DNA pada sel kanker mulut menunjukkan bahwa sponge mengambat OSCC. Disimpulkan bahwa senyawa turunan marine sponges dapat berperan dalam apoptosis, antiproliferasi, sitotoksik pada sel kanker mulut sehingga berpotensi menghambat OSCC.