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All Journal Cendana Medical Journal Journal of Comprehensive Science JUKEJ: Jurnal Kesehatan Jompa
Desi Indriarini
Universitas Nusa Cendana
Computer Science & IT Economics, Econometrics & Finance Electrical & Electronics Engineering Health Professions Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Nursing Public Health Veterinary

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Perbandingan Pelarut Ekstrak Air, Etanol 70%, dan N-Heksana Herba Utasupe terhadap Kandungan Metabolit Sekunder Menggunakan Skrining Fitokimia Alsen Diamel Oematan; Listyawati Nurina; Desi Indriarini; Anita L. Shinta Amat; Muhajirin Dean
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 2 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss2.2679

Abstract

Traditional medicine is a medicine that is used for generations from ancestors and inherited until now. The use of herbal medicinal products in the last three decades has increased rapidly. Indonesia is one of the countries that has a lot of biodiversity. Indonesia has millions of varieties of plants that can be used as herbal medicine. Utasupe is a plant that is one of the herbal medicines used by people from Ende Island, Ende Regency, East Nusa Tenggara Province as an herbal medicine for constipation conditions. Knowing the comparison of secondary metabolite compounds of water extract, 70% ethanol, and n-hexane Herba Utasupe from Ende Island District. Research used in true experimental design research with posttest only control group design research design. This study used phytochemical screening methods, to see changes in color/shape that indicate the presence and absence of secondary metabolite compounds present in water extracts, 70% ethanol, and n- hexane Utasupe herbaceous plants from Ende Island District. The sample in this study was Utasupe Herba plants that met the inclusion criteria and exclusion criteria. Data analysis using nonparametric statistical methods, namely the fisher test. In water and ethanol solvents 70% obtained groups of secondary metabolite compounds alkaloids, flavonoids, tannins, and saponins. While in n-hexane solvents obtained a class of secondary metabolite compounds of alkaloids, flavonoids, steroids, and tannins. In statistical analysis using the fisher test, p values were obtained: 0.200 – 0.100 (p > 0.005). The results of this fisher test show that there is no significant difference between the three solvents. There is no comparison between water solvent, 70% ethanol, and n- hexane based on the results of statistical analysis using the Fisher test.
Activity Test of Anti-Dandruff Shampoo Preparation of Fragrant Pandan Leaf Extract (Pandanus Amaryllifolius Roxb.) Against the fungus Malassezia Furfur Arini Aprili Pallo; Prisca Deviani Pakan; Desi Indriarini; Magdarita Riwu
Journal of Comprehensive Science Vol. 5 No. 2 (2026): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v5i2.4022

Abstract

Dandruff is a scalp disorder caused by Malassezia furfur fungus, often treated with anti-dandruff shampoos. However, synthetic active ingredients in such shampoos may cause side effects like scalp irritation, dryness, or allergies. As an alternative, herbal formulations using fragrant pandan leaves (Pandanus amaryllifolius Roxb.), known for their antifungal properties, can be developed. The objective of this study was to determine and analyze the best Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo formulation and its antifungal activity against Malassezia furfur. The type of research conducted was a true experimental study with a Post-Test Only Control Group Design. In this study, there were treatment groups given a shampoo preparation of fragrant pandanus leaf extract at concentrations of 30%, 50%, and 70%, a negative control group of a shampoo base, and a positive control group of a shampoo containing 1% selenium sulfide under the brand name Selsun. The analysis used was the One-Way ANOVA test. The shampoo preparation of fragrant pandanus leaf extract demonstrated antifungal activity against Malassezia furfur, with inhibition zones obtained at a 30% concentration (15.83 mm), 50% concentration (18.68 mm), 70% concentration (21.89 mm), positive control (21.36 mm), and negative control (0 mm). The 70% Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo preparation is the best formulation because it exhibits optimal physical characteristics and produces the greatest inhibition against Malassezia furfur.
Efektivitas Formula Sediaan Sampo Antijamur Ekstrak Kulit Pisang Kepok (Musa paradisiaca L.) Terhadap Pertumbuhan Malassezia furfur Maria Vianey Dominika Seda Pia; Prisca Deviani Pakan; Iswa Ningsih; Desi Indriarini
Cendana Medical Journal Vol 14 No 1 (2026): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v14i1.27362

Abstract

Abstract Background: Malassezia furfur is a pathogenic organism that causes dandruff. One way to prevent dandruff is by washing the hair using shampoo that contains anti-dandruff active ingredients. Continuous use of synthetic shampoos can cause the hair to become dry, easily brittle, irritate the eyes and scalp, and damage the hair shaft. Herbal shampoos have become popular due to consumers’ belief that they contain natural ingredients that are safer and have minimal side effects. One natural ingredient that can be used is the peel of kepok banana (Musa paradisiaca L.). Objective: To determine the antifungal activity of a shampoo formulation containing kepok banana peel extract (Musa paradisiaca L.) against the growth of Malassezia furfur. Methods: The type of research conducted was a true experimental study with a post-test only control group design. In this study, there were treatment groups given shampoo containing kepok banana peel extract at concentrations of 1.56%, 3.125%, 6.25%, 12.5%, 25%, 50%, and 100%, a negative control group using the shampoo base, and a positive control group using shampoo containing 1% selenium sulfide. The data were analyzed using One-Way ANOVA. Results: All shampoo formulations showed suboptimal physical characteristics. Concentrations of 6.25%, 12.5%, 25%, 50%, and 100% demonstrated antifungal activity against the growth of Malassezia furfur. Conclusion: There is antifungal activity from the shampoo formulation containing kepok banana peel extract (Musa paradisiaca L.) against the growth of Malassezia furfur.
Co-Authors Alsen Diamel Oematan Anita L. Shinta Amat Arini Aprili Pallo Iswa ningsih Magdarita Riwu Maria Vianey Dominika Seda Pia Nurina, Rr. Listyawati Prisca Deviani Pakan