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All Journal Jurnal Ilmiah Flash Acta Biochimica Indonesiana Cendana Medical Journal Journal of Comprehensive Science
Prisca Deviani Pakan
Universitas Nusa Cendana
Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Electrical & Electronics Engineering Health Professions Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Public Health

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PENERAPAN PCA PADA KLASIFIKASI DATA MIKRO ARAY GEN MENGGUNAKAN JARINGAN SYARAF TIRUAN Prisca Deviani Pakan
Jurnal Ilmiah Flash Vol 5 No 2 (2019)
Publisher : P3M- Politeknik Negeri Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32511/flash.v5i2.679

Abstract

Penelitian ini dilakukan dengan melakukan analisa terhadap data micorarray, selanjutnya ekspresi dari ribuan gen yang merepresentasikan suatu jaringan pada manusia, akan diklasifikasikan sebagai jaringan kanker atau bukan setelah dilakukan proses reduksi dimensi menggunakan algoritma PCA. Tahapan Klasifikasi dilakukan menggunakan algoritma jaringan syaraf tiruan
PERAMALAN KASUS POSITIF COVID 19 DI INDONESIA MENGGUNAKAN LSTM Prisca Deviani Pakan
Jurnal Ilmiah Flash Vol 6 No 1 (2020)
Publisher : P3M- Politeknik Negeri Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32511/flash.v6i1.681

Abstract

Kasus Pandemi COVID 19 telah terjadi secara massif dan mengganggu ketahanan Kesehatan dunia. Jumlah kasus yang terus bertambah diseluruh negara di dunia, membutuhkan penanganan yang cepat dan tepat. Penelitian ini bertujuan untuk mengembangkan suatu metode peramalan jumlah kasus penyebaran wabah COVID 19 menggunakan Jaringan Syaraf Tiruan Long Short Term Memory
KLASIFIKASI KANKER LEUKIMIA MENGGUNAKAN MICROARRAY EKSPRESI GEN Prisca Deviani Pakan
Jurnal Ilmiah Flash Vol 4 No 2 (2018)
Publisher : P3M- Politeknik Negeri Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (979.001 KB) | DOI: 10.32511/flash.v4i2.288

Abstract

Kanker adalah sebuah penyakit yang disebabkan oleh pembelahan secara berlebihan dan tak terkendali darisel-sel dalam tubuh. Teknologi DNA microarray telah memungkinkan untuk mengamati beribu-ribu ekspresi gen dalam waktu bersamaan. Tingkat ekspresi gen dapatdigunakan untuk menentukan jenis sel kanker dari seorang penderita. Penelitian ini bertujuan untuk mengevaluasi kemampuan machine learning dalam mengklasifikasi kanker leukimia menggunakan data microarray ekspresi gen. Hasil percobaan menunjukan bahwa jaringan syaraf tiruan memiliki akurasi sebesar 98% lebih tinggi dibandingkan dengan algoritma lain.
Activity Test of Anti-Dandruff Shampoo Preparation of Fragrant Pandan Leaf Extract (Pandanus Amaryllifolius Roxb.) Against the fungus Malassezia Furfur Arini Aprili Pallo; Prisca Deviani Pakan; Desi Indriarini; Magdarita Riwu
Journal of Comprehensive Science Vol. 5 No. 2 (2026): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v5i2.4022

Abstract

Dandruff is a scalp disorder caused by Malassezia furfur fungus, often treated with anti-dandruff shampoos. However, synthetic active ingredients in such shampoos may cause side effects like scalp irritation, dryness, or allergies. As an alternative, herbal formulations using fragrant pandan leaves (Pandanus amaryllifolius Roxb.), known for their antifungal properties, can be developed. The objective of this study was to determine and analyze the best Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo formulation and its antifungal activity against Malassezia furfur. The type of research conducted was a true experimental study with a Post-Test Only Control Group Design. In this study, there were treatment groups given a shampoo preparation of fragrant pandanus leaf extract at concentrations of 30%, 50%, and 70%, a negative control group of a shampoo base, and a positive control group of a shampoo containing 1% selenium sulfide under the brand name Selsun. The analysis used was the One-Way ANOVA test. The shampoo preparation of fragrant pandanus leaf extract demonstrated antifungal activity against Malassezia furfur, with inhibition zones obtained at a 30% concentration (15.83 mm), 50% concentration (18.68 mm), 70% concentration (21.89 mm), positive control (21.36 mm), and negative control (0 mm). The 70% Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo preparation is the best formulation because it exhibits optimal physical characteristics and produces the greatest inhibition against Malassezia furfur.
Antibacterial potential of celery (Apium graveolens L.) extract gel against Staphylococcus aureus Martinus Ezra Sunarno; Anita Lidesna Shinta Amat; Arley Sadra Telussa; Prisca Deviani Pakan
Acta Biochimica Indonesiana Vol. 7 No. 2 (2024): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.154

Abstract

Background: Staphylococcus aureus can cause furuncles or boils, painful nodules on the skin. Conventional topical therapies often lead to side effects such as contact dermatitis and pruritus, compounded by the increasing problem of antibiotic resistance. Natural ingredients like celery (Apium graveolens L.) offer promising alternatives due to their antibacterial properties and gentler effects. Objective: This study aimed to formulate a celery extract gel with ideal physical characteristics and evaluate its antibacterial potency against Staphylococcus aureus. Methods: Celery extract gel was prepared using HPMC, celery extract, methylparaben, propylparaben, and propylene glycol. Formulations with various celery extract concentrations were tested alongside mupirocin ointment (positive control) and gel base (negative control) against Staphylococcus aureus using the well-diffusion method. The results were analyzed using the One-Way ANOVA statistical test. Results: Celery extract gel demonstrated strong antibacterial potency at 25% (F1), 50% (F2), and 75% (F3) concentrations and very strong potency at 100% (F4). The One-Way ANOVA analysis showed a significant difference in the mean inhibitory zone diameter between treatment groups (p < 0.05). Conclusion: Celery extract gel exhibits significant antibacterial activity against Staphylococcus aureus, suggesting its potential as a natural alternative for topical therapy in managing skin infections.
LITERATURE REVIEW PERBANDINGAN EFEKTIVITAS EKSTRAK TANAMAN KELOR (Moringa oleifera) DENGAN KETOKONAZOL DALAM MENGHAMBAT PERTUMBUHAN Candida sp. PADA Saboraud Dextrose Agar Lidya Lyke Sonbait; Prisca Deviani Pakan; Idawati Trisno; Christina Olly Lada
Cendana Medical Journal Vol 14 No 1 (2026): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v14i1.18538

Abstract

Background: One of the fungi that often causes infectious diseases is Candida albicans with a worldwide prevalence of 66%. Candidiasis as a disease caused by Candida albicans infection can be found throughout the world and is able to attack all ages, both men and women. Purpose: To compare the effectiveness of Moringa oleifera plant extract with ketoconazole in inhibiting Candida sp. on Saboraud Dextrose Agar. Methods: The method of searching for article data sources is carried out through the Google Scholar and PubMed databases (2015-2020) to retrieve relevant articles published in English and Indonesian. Key terms and phrases related to the comparative effectiveness of Moringa oleifera, ketoconazole, Candida sp. growth, Saboraud Dextrose Agar used in the subject search. Results: Based on the results of a literature review from 23 journals consisting of comparative characteristics of the effectiveness of Moringa oleifera and ketoconazole plant extracts, 11 journals found that ketoconazole Moringa oleifera plant extract was more effective than ketoconazole, while 12 other journals said that ketoconazole was more effective. By doing a comparison between the two methods, it was found that ketoconazole was more effective to be used in inhibiting the growth of Candida sp. than Moringa oleifera plant extract. Conclusion: Based on 23 journals conducted by a literature review, it can be concluded that ketoconazole has better effectiveness in inhibiting the growth of Candida sp. than Moringa oleifera plant extract.
Utilization of Kersen Leaf Extract (Muntingia calabura L.) in Non Aerosol Foot Spray Preparation as Antibacterial Against Staphylococcus epidermidis Nadhifa Ainun Syafira; Prisca Deviani Pakan
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.27121

Abstract

Introduction: The condition of the feet that are often covered by socks and shoes causes the feet to become sweaty and moist. If the sweat is mixed with the bacteria that are involved in the degradation process, it will cause an odor. Preventing foot odor requires a convenient antibacterial product such as foot spray. However, many foot spray products contain high levels of alcohol, which can cause skin irritation. Therefore, the implementation of natural antibacterial ingredients needs to be incorporated to reduce its use, such as kersen leaves (Muntingia calabura L.). Objectives: Knowing and analyzing foot spray preparations and their benefits as antibacterial against Staphylococcus epidermidis. Method: This research is a true experimental design with a post-test only control group. The study involved five treatment groups: kersen leaf extract foot spray at concentrations of 1%, 5%, and 10%; a positive control group consisting of commercial foot spray (Guardian); and a negative control group which utilized foot spray base with S. epidermidis as the test bacteria. The method of antibacterial testing uses the disc diffusion method. The results were analyzed using the One-Way Anova statistical test. Result: The kersen leaf extract foot spray preparation was tested for its ability to inhibit the growth of S. epidermidis. Results showed that the inhibition zone diameter at 1% concentration was moderate (7.82 mm), while at 5% concentration it remained moderate (8.62 mm), and at 10% concentration it classified as strong (10.28 mm). The analysis results found significant differences between treatment groups with a significance value of p < 0.05. Conclusion: Kersen leaf extract (Muntingia calabura L.) foot spray preparation has antibacterial activity against Staphylococcus epidermidis and all formulations have optimal physical characteristics. Keywords: Kersen Leaf Extract; Muntingia calabura L.; Foot Spray; Antibacterial; Staphylococcus epidermidis
Efektivitas Formula Sediaan Sampo Antijamur Ekstrak Kulit Pisang Kepok (Musa paradisiaca L.) Terhadap Pertumbuhan Malassezia furfur Maria Vianey Dominika Seda Pia; Prisca Deviani Pakan; Iswa Ningsih; Desi Indriarini
Cendana Medical Journal Vol 14 No 1 (2026): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v14i1.27362

Abstract

Abstract Background: Malassezia furfur is a pathogenic organism that causes dandruff. One way to prevent dandruff is by washing the hair using shampoo that contains anti-dandruff active ingredients. Continuous use of synthetic shampoos can cause the hair to become dry, easily brittle, irritate the eyes and scalp, and damage the hair shaft. Herbal shampoos have become popular due to consumers’ belief that they contain natural ingredients that are safer and have minimal side effects. One natural ingredient that can be used is the peel of kepok banana (Musa paradisiaca L.). Objective: To determine the antifungal activity of a shampoo formulation containing kepok banana peel extract (Musa paradisiaca L.) against the growth of Malassezia furfur. Methods: The type of research conducted was a true experimental study with a post-test only control group design. In this study, there were treatment groups given shampoo containing kepok banana peel extract at concentrations of 1.56%, 3.125%, 6.25%, 12.5%, 25%, 50%, and 100%, a negative control group using the shampoo base, and a positive control group using shampoo containing 1% selenium sulfide. The data were analyzed using One-Way ANOVA. Results: All shampoo formulations showed suboptimal physical characteristics. Concentrations of 6.25%, 12.5%, 25%, 50%, and 100% demonstrated antifungal activity against the growth of Malassezia furfur. Conclusion: There is antifungal activity from the shampoo formulation containing kepok banana peel extract (Musa paradisiaca L.) against the growth of Malassezia furfur.
Co-Authors Anita Lidesna Shinta Amat Arini Aprili Pallo Arley Sadra Telussa Christina Olly Lada Desi Indriarini Idawati Trisno Iswa ningsih Lidya Lyke Sonbait Magdarita Riwu Maria Vianey Dominika Seda Pia Martinus Ezra Sunarno Nadhifa Ainun Syafira