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All Journal Jurnal Kedokteran Hewan The International Journal of Tropical Veterinary and Biomedical Research
M. Jalaluddin, M.
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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INHIBITORY POWER TEST OF N-HEXANE EXTRACT OF MALAKA LEAVES (Phyllanthus emblica) ON GROWTH Microsporum canisIN-VITRO Miranda, Lola Almira; Asmilia, Nuzul; Fakhrurrazi, Fakhrurrazi; Rusli, Rusli; Amiruddin, Amiruddin; Jalaluddin, M.
The International Journal of Tropical Veterinary and Biomedical Research Vol 10, No 1 (2025): Vol 10 (1) May 2025
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v10i1.48192

Abstract

Background and Aim: Malacca leaves are one of the medical plants that can be used in traditional medicine. Malacca leaves contain several active compounds that can be effective in inhibiting fungal growth. This study aims to investigate the inhibition of n-hexane Malacca leaves extract on Microsporum canis growth in vitro.Materials and Methods: The method used in this study is Kirby-Bauer disc diffusion with 5 treatments, namely P1 (25% Malacca leaves n-hexane extract), P2 (50% Malacca leaves n-hexane extract), P3 (75% Malacca leaves n-hexane extract), P4 (control (+): ketoconazole) and P5 (control (-): carboxymethylcellulose (CMC) 1%) with 3 replications. The clear zone formed around the disc was measured using a caliper.Results : The results showed that there was no clear zone formed around the disks of the n-hexane extract of Malacca leaves. It can be concluded that the n-hexane extract of Malacca leaves could not inhibit the growth of Microsporum canis.Conclusion: The findings of this study indicate that the n-hexane extract of Malacca leaves, at concentrations of 25%, 50%, and 75%, does not exhibit antifungal activity against Microsporum canis in vitro, as evidenced by the absence of inhibition zones. Therefore, n-hexane may not be an effective solvent for extracting antifungal compounds from Malacca leaves against this fungal species.
STUDI ANATOMIS DAN HISTOLOGIS PANKREAS BIAWAK AIR (Varanus salvator) (Anatomical and Histological Study of the Pancreas of Water Monitor Lizard (Varanus salvator)) Hamny, Hamny; Iqbal, Muhammad; Wahyuni, Sri; Sabri, Mustafa; Jalaluddin, M.; Rinidar, Rinidar
Jurnal Kedokteran Hewan Vol 10, No 2 (2016): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v10i2.5047

Abstract

The aim of this research was to determine the anatomy and histology of pancreas of water monitor lizard (Varanus salvator). Two pancreas were used in this research (a male and a female). Water monitor lizard was euthanized using chloroform and subsequently necropsied to collect the pancreas. The pancreas was washed in 0.9 % NaCl solution. Anatomical observations were carried out including location, shape, and color of pancreas, also the length and weight measurements. Then, pancreas was fixed with 4% paraformaldehyde for 7 days to proceed to histological preparation and hematoxylin eosin (HE) staining. The results of the anatomical observations showed that pancreas of water monitor lizard have two lobes, dorsal lobe (splenic lobe) and ventral lobe (duodenal lobe). Dorsal lobe which was in oval form adhered with the spleen, and ventral lobe was located in the cranial of intestines with the form of long spherical. Both of pancreas lobes were white-yellow color with the length of 1.450.64 cm (dorsal lobe) and 7.000.42 cm (ventral lobe). Weight of dorsal lobe was 0.150.01 g and ventral lobe was 6.352.30 g. The histological observations found the acinar cells, ducts, and blood vessels in both of pancreas lobes. Additionally, the similar structure of Langerhans islet only found at the ventral lobe of pancreas. In conclusion, pancreas of water monitor lizard consists of two lobes which located differently. Ventral lobe is larger than the dorsal lobe. Both lobes have similar histological structure except the Langerhans islets are only appeared in the ventral lobe.
Co-Authors - Fakhrurrazi Amiruddin Amiruddin Faisal Mustafa Hamny Hamny Miranda, Lola Almira Muhammad Iqbal Nuzul Asmilia R. Rusli Rinidar Rinidar, Rinidar Sri Wahyuni