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All Journal e-CliniC JURNAL BIOMEDIK Medical Scope Journal (MSJ) Jurnal Neuroanestesi Indonesia
Diana C. Lalenoh, Diana C.
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Profil Pasien Pasca Laparotomi di ICU RSUP Prof. Dr. R. D. Kandou Manado Periode Januari 2015 sampai Desember 2017 Tanio, Pratiwi N.; Lalenoh, Diana C.; Laihad, Mordekhai L.
e-CliniC Vol 6, No 2 (2018): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v6i2.22122

Abstract

Abstract: Laparotomy is a surgical procedure involving an incision through the abdomen. Laparotomy can be performed on patients with hemoperitoneum due to abdominal trauma, gastrointestinal bleeding, acute abdominal pain, chronic abdominal pain, and if there is an intra-abdominal clinical finding that requires emergency surgery, such as pertonitis as well as ileus (obstruction or perforation). This study was aimed to obtain the profile of post laparotomy patients at ICU Prof. Dr. R. D. Kandou Hospital Manado from January 2015 to December 2017. This was a descriptive retrospective study using medical record data of post laparotomy patients at Prof. Dr. R. D. Kandou Hospital Manado. There were 107 post laparotomy patients at the ICU. The highest percentages were found in: peritonitis (38.3%), males (62%), and ages 45-64 years (50%). There were 87% of post laparotomy patients that used mechanical ventilators. The average of length of stay of post laparotomy patients in ICU was 7-14 days (33%). There were 40 patients (37%) in 24-48 hours after admission in the ICU and caused by sepsis (77.5%). Conclusion: Most post laparotomy patients were 45-64 years old, male, had main diagnosis as peritonitis, length of stay of 7-14 days, and used mechanical ventilators. Moreover, there were 40 patients died in 24-48 hours after admission.Keywords: laparotomy, peritonitis, mortality, length of stayAbstrak: Laparotomi adalah suatu tindakan bedah berupa insisi pada dinding perut atau abdomen. Laparotomi dapat dilakukan pada pasien yang menderita trauma abdomen dengan hemoperitoneum, perdarahan gastrointestinal, nyeri abdomen akut, nyeri abdomen kronik, dan jika ditemukan kondisi klinis intra abdomen yang membutuhkan pembedahan darurat seperti peritonitis, ileus obstruksi, dan perforasi. Penelitian ini bertujuan untuk mengetahui profil pasien pasca laparotomi di ICU RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2015 - Desember 2017. Jenis penelitian ialah deskriptif retrospektif, menggunakan data rekam medik pasien pasca laparotomi di RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian mendapatkan 107 orang pasien pasca laparotomi di ICU dengan diagnosis penyakit terbanyak pada peritonitis (38,3%), jenis kelamin laki-laki (62%), dan usia 45-64 tahun (50%). Pasien pasca laparotomi banyak yang menggunakan ventilator mekanik (87%). Rerata lama perawatan pasien pasca laparotomi di ICU 7-14 hari (33%). Terdapat 40 orang yang meninggal (37%) pada 24-48 jam dirawat di ICU, dan disebabkan oleh sepsis (77,5%). Simpulan: Pasien pasca laparotomi terbanyak pada usia 45-64 tahun, jenis kelamin laki-laki, dengan diagnosis penyakit dilakukan laparotomi peritonitis, lama rawat ICU 7-14 hari, dan menggunakan ventilator mekanik. Didapatkan 40 pasien yang meninggal pada 24-48 jam dirawat di ICU.Kata kunci: laparotomi, peritonitis, mortalitas, lama rawat inap
Profil penderita sepsis di ICU RSUP Prof. Dr. R. D. Kandou Manadoperiode Desember 2014 – November 2015 Tambajong, Rheza N.; Lalenoh, Diana C.; Kumaat, Lucky
e-CliniC Vol 4, No 1 (2016): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.4.1.2016.11011

Abstract

Abstract: Sepsis (blood poisoning) is an acute and serious clinical condition due to the presence of pathogenic microorganisms or their toxins in the bloodstream. The incidence of sepsis continues to rise over the past three decades. Although the knowledge of pathophysiology and therapy has developed supported by specific antibiotic therapy, sepsis is still the main cause of non-cardiac death in Intensive Care Unit (ICU). This study was aimed to determine the profile of patients with sepsis and its classification in the ICU. This was a descriptive retrospective study. Samples were determined by using non-probability sampling method, the purposive sampling method. Samples were septic patients at ICU Prof. Dr. R. D. Kandou Hospital Manado obtained from data of the medical records from December 2014 to November 2015. The results showed that there were 35 septic patients consisted of 16 males (46%) and 19 females (54%); most were geriatric patients. There were 29 patients (82.8%4 patients) diagnosed as sepsis; 4 patients (11.4%) as severe sepsis; and 2 patients (5.7%) as septic shock. Of the total 35 patients, there were 12 survivors (34.3%) and 23 deaths (65.7%)Keywords: septic patients Abstrak: Sepsis adalah kondisi klinis akut dan serius yang muncul akibat adanya mikroorganisme patogen atau toksinnya dalam aliran darah. Kejadian sepsis terus meningkat selama tiga dekade terakhir, Meskipun pemahaman patofisiologi dan terapi meningkat serta didukung oleh terapi antibiotik yang spesifik, sepsis dilaporkan tetap menjadi penyebab dari kematian non-cardiac di Intensive Care Unit (ICU). Penelitian ini bertujuan untuk mendapatkan profil penderita sepsis dan klasifikasinya di ICU. Jenis penelitian ialah deskriptif retrospektif. Sampel penelitian ialah pasien ICU RSUP Prof. Dr. R. D. Kandou Manado dengan diagnosis sepsis dan klasifikasinya diperoleh dari data di Bagian Rekam Medik periode Desember 2014 – November 2015. Besar sampel ditentukan dengan metode purposive sampling. Hasil penelitian mendapatkan total 35 sampel dengan sepsis terdiri dari 16 orang laki-laki (46%) dan 19 orang perempuan (54%); sebagian besar ialah pasien geriatri. Pasien yang didiagnosis masuk sepsis yang terbanyak yaitu 29 orang (82,8%) dibandingkan dengan diagnosis lain yaitu severe sepsis sebanyak 4 orang (11,4%) dan syok sepsis sebanyak 2 orang (5,7%). Dari ke 35 pasien dengan sepsis, 12 orang berhasil selamat (34.3%) sedangkan 23 orang meninggal (65.7%). Kata kunci: pasien sepsis
Profil Penggunaan Antibiotik pada Pasien Sepsis dan Syok Septik di Ruang Perawatan Intensif Prof. Dr. R. D. Kandou Manado Kowel, Feysira C. E. P.; Lalenoh, Diana C.; Laihad, Mordekhai L.
e-CliniC Vol. 13 No. 2 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i2.60875

Abstract

Abstract: Gram-negative and gram-positive bacteria are common causes of sepsis and septic shock, therefore, treatment often uses broad spectrum antibiotics. This study aimed to determine the types of antibiotics used, the suitability of antibiotics with etiology, and the average length of antibiotic use in sepsis and septic shock patients at Prof. Dr. R. D. Kandou Hospital Manado from July 2022 to June 2023. This was a descriptive and retrospective study using patients’ medical records. The results showed that the use of antibiotics in sepsis and septic shock included monotherapy and combination therapy. The most common antibiotics for monotherapy was levofloxacine (14.3%) in sepsis, and meropenem (8.7%) in septic shock. The most common combination for sepsis was meropenem-levofloxacine (6.7%) and meropenem-metronidazole (6.7%), meanwhile for septic shock was meropenem-levofloxacine (16.5%). Of the 91 sepsis patients, only 15 had the causative germs; 10 (9.62%) antibiotics did not match the etiology, eight (7.84%) did. In septic shock, of 91 patients, five patients had the causative germs; four (4.44%) antibiotics were according to etiology, three (3.37%) were not appropriate. The average use of antibiotics was one day, with an average value of 3.06 for sepsis and 2.24 for septic shock. In conclusion, in patients with sepsis and septic shock, the monotherapy is levofloxacine and meropenem, while the combination therapies are meropenem-levofloxacine and meropenem-metronidazole. Antibiotics appropriate to the etiology in sepsis and septic shock sepsis have nearly the same number with those inappropriate to etiology. The average duration of antibiotic use for both sepsis and septic shock is one day. Keywords: antibiotics; sepsis; septic shock; profile of antibiotics usage   Abstrak: Bakteri Gram-negatif dan Gram-positif merupakan penyebab umum sepsis dan syok septik, sehingga pengobatannya sering menggunakan antibiotik spektrum luas. Penelitian ini bertujuan untuk mengetahui jenis antibiotik yang digunakan, kesesuaian antibiotik dengan etiologi, rerata lama penggunaan antibiotik pada pasien sepsis dan syok septik di RSUP Prof. Dr. R. D. Kandou Manado periode Juli 2022–Juni 2023. Jenis penelitian ialah deskriptik retrospektif menggunakan data rekam medis pasien sepsis dan syok septik. Hasil penelitian mendapatkan penggunaan antibiotik pada sepsis dan syok septik meliputi monoterapi dan kombinasi. Antibiotik yang umum digunakan untuk monoterapi ialah levofloxacine (14,3%) pada sepsis, dan meropenem (8,7%) pada syok septik; untuk kombinasi meropenem-levofloxacine (6,7%) dan meropenem-metronidazole (6,7%) pada sepsis dan meropenem-levofloxacine (16,5%) pada syok septik. Dari 91 pasien sepsis, hanya 15 yang memiliki kuman penyebab; 10 (9,62%) antibiotik tidak sesuai etiologi, dan delapan (7,84%) sesuai. Pada syok septik, dari 91 pasien, lima memiliki kuman penyebab; empat (4,44%) antibiotik sesuai etiologi, dan tiga (3,37%) tidak sesuai. Rerata penggunaan antibiotik terbanyak ialah satu hari, dengan nilai rerata 3,06 untuk sepsis dan 2,24 untuk syok septik. Simpulan penelitian ini ialah antibiotik yang banyak digunakan pada pasien sepsis dan syok septik sebagai monoterapi yaitu levofloxacine dan meropenem, sedangkan untuk kombinasi ialah meropenem-levofloxacine dan meropenem-metronidazole. Antibiotik yang sesuai etiologi baik pada sepsis maupun syok septik hampir sama banyak dengan yang tidak sesuai etiologi.  Rerata lama penggunaan antibiotik baik sepsis maupun syok septik ialah satu hari. Kata kunci: antibiotik; sepsis; syok septik; profil penggunaan antibiotik
Co-Authors Firdaus, Riyadh Firdaus, Riyadh Kambey, Barry I. Kowel, Feysira C. E. P. Laihad, Mordekhai L. Lucky Kumaat Masikome, Jessica N. Permatasari, Endah Rheza N. Tambajong, Rheza N. Sri Rahardjo Subekti, Bambang Eko Subekti, Bambang Eko Tanio, Pratiwi N. Tatang Bisri Wonggo, Tesalonika