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All Journal Majalah Kedokteran Bandung Althea Medical Journal Indonesian Journal of Cardiology Heart Science Journal
Achmad Fauzi Yahya, Achmad Fauzi
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Health Professions Immunology & microbiology Medicine & Pharmacology

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Effect of Midnight Prayer on Sympathetic Tone Kencanasari, Hadiyatussalamah Pusfa; Yahya, Achmad Fauzi; Setiawan, Setiawan
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.896 KB)

Abstract

Background: Hypertension is one of the most dangerous ailments which most common risk factor is stress that can activate sympathetic system leading to increased blood pressure. Midnight prayer is believed to calm mind. This study was conducted to discover the effect of midnight prayer on sympathetic tone.Methods: This cross sectional study was conducted in Bina Siswa Senior High SchoolSMA Plus Cisarua Boarding School, Lembang from October to November 2013. Sixty eight participants were divided into 3 groups based on frequency; high, low, and non midnight prayer. Blood pressure and pulse rate of participants were examined before, during, and after the cold pressor test is taken. Blood pressure and pulse rate duration of recovery were also measured.Results: This study showed no significant difference between 3 groups in term of systolic blood pressure, diastolic blood pressure, and pulse rate. However, the lowest mean of pulse rate (64.38±8.921 vs 66.69±11.482 vs 65.44±9.584 respectively), systolic blood pressure [107.19±6.945 vs 117.13±13.426 vs 104.25 (75–120) respectively], and diastolic blood pressure [70.38±7.719 vs 77.38±10.935 vs 70.63±7.491 respectively] were obtained in the high midnight prayer group. Recovery duration of blood pressure [6.38 (6–8) vs 6.72 (6–11) vs 6.75 (6–11) respectively] and pulse rate (6.69±0.946 vs 7.03±1.341 vs 7.00±1.506 respectively) among the groups showed no significant difference respectively, however the shortest duration was obtained in the high midnight prayer group.Conclusions: Midnight prayer has no significant effect on sympathetic tone. [AMJ.2016;3(1):59–63]DOI: 10.15850/amj.v3n1.692
Association between Neutrophil-Lymphocyte Count Ratio and Matrix Metalloproteinase-9 in Patients with Acute Myocard Infarction Tiksnadi, Badai Bhatara; Akbar, Muhammad Rizki; Yahya, Achmad Fauzi; Hidayat, Syarief; Purnomowati, Augustine; Aprami, Toni Mustahsani
Majalah Kedokteran Bandung Vol 51, No 1 (2019)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (614.44 KB) | DOI: 10.15395/mkb.v51n1.1405

Abstract

The correlation between metalloproteinase-9 (MMP-9) level and neutrophil-lymphocyte count ratio (NLCR) in AMI patients has not been studied despite the fact that they are both known to predict ventricular remodeling. This study aimed to evaluate the correlation between the MMP-9 level and NLCR in patients with acute myocardial infarction. A cross-sectional study was conducted by recruiting acute coronary syndrome patients (onset within 24 hours) who were admitted to the emergency department in several hospitals around Bandung during October-December 2012. The relationship between the MMP-9 level and NLCR was analyzed using Pearson correlation test. Linear regression analysis was used to measure the strength of NLCR in MMP-9 level prediction. Thirty seven patients aged 55.8 + 11 years old were included in this study with mostly male patients (78%). Seventy-six percents of the sample were ST-elevation myocardial infarct (STEMI) patients with the onset of symptoms of 6 (3-14) hours. The mean lymphocyte-neutrophil ratio was 5.24 (1σ±2.4) and the MMP-9 plasma concentration was 370 (240-530) ng/mL. One-sided Pearson correlation showed a positive correlation between the two variables (r=0.44, p=0.003). The linear regression analysis conceived the formula of MMP-9 = 40.87 (NLCR) + 211.3 which was used to show the relationship between the MMP-9 level and lymphocyte-neutrophil ratio. There was a positive moderate correlation between the MMP-9 level and NLCR in patients with AMI. Linear regression analysis shows that NLCR is the only independent variable to predict the MMP-9 plasma level.Key words: Acute myocardial infarct, left ventricular remodeling, matrix metalloproteinase (MMP)-9, neutrophyl-lymphocyte count Ratio (NLCR) Korelasi Rasio Neutrofil-Limfosit (NLCR) dengan Kadar Matriks Metaloproteinase-9 pada Penderita Infark Miokardium AkutKorelasi antara matriks metaloproteinase-9 (MMP-9) dan rasio netrofil-limfosit masih belum pernah dipelajari, meskipun kedua variable tersebut diketahui dapat memprediksi remodeling ventrikel kiri. Studi ini bertujuan mengevaluasi korelasi antara kadar MMP-9 dan rasio netrofil-limfosit pada penderita infark miokardium akut. Penelitian dilakukan secara potong lintang menggunakan sampel darah pasien dengan diagnosis kerja infark miokardium akut (IMA) (onset nyeri dada <24 jam) yang diambil dari beberapa rumah sakit di sekitar Kota Bandung dari periode Bulan Oktober–Desember 2012. Hubungan antara kadar MMP-9 dan rasio neutrofil leukosit dianalisis menggunakan uji korelasi Pearson. Analisis regresi linier digunakan untuk mengukur kekuatan pengaruh konsentrasi rasio neutrofil-limfosit pada kadar MMP-9. Sebanyak 37 pasien berusia 55,8 +11 tahun, dan 78% di antaranya adalah pria menjadi subjek dalam penelitian ini. Tujuh puluh enam persen sampel diantaranya merupakan pasien infark miokardium dengan elevasi ST dengan onset gejala 6 (3–14) jam.  Rerata rasio limfosit-neutrofil adalah 5,24 (1σ ±2,4), dan kadar konsentrasi MMP-9 sebesar 370 (240–530) ng/ml. Uji Korelasi Pearson menunjukkan hubungan positif antara kedua variabel tersebut dengan nilai r=0,44 (p=0,003).  Dari analisis regresi linier didapatkan rumus MMP-9= 40,87 (NLCR) + 211,3, yang digunakan untuk menunjukkan hubungan antara kadar MMP-9 dan rasio limfosit-netrofil. Terdapat hubungan positif antara kadar MMP-9 dan rasio neutrofil-limfosit pada pasien penderita IMA. Analisis regresi linier menunjukkan bahwa hanya rasio neutrofil-limfosit yang menjadi variabel prediktor independen kadar MMP-9.Kata kunci: Infark neutrofil akut, matriks-metaloproteinase 9 (MMP-9), rasio limfosit-neutrofil, remodeling ventrikel kiri
Long term radial artery occlusion following distal or proximal transradial artery access in invasive cardiovascular procedures Saboe, Aninka; Ibrahim, Maulana; Pranata, Raymond; Dewi, Triwedya Indra; Yahya, Achmad Fauzi
Heart Science Journal Vol. 6 No. 2 (2025): The Complexity in the Management of Heart Rhythm Disorder
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.02.10

Abstract

Background: Radial artery occlusion (RAO) is one of the most common consequences of transradial artery access (TRA) in invasive cardiovascular procedures; therefore, alternative approaches, such as distal radial artery access (DRA), emerged. This study compares proximal and distal radial access for long-term RAO. Objectives: This study compares long-term RAO incidence with proximal and distal radial access following invasive cardiovascular procedures. Material and Methods: This is a retrospective cohort study. The subjects comprised patients with heart disease who underwent invasive cardiovascular procedures using radial access at Dr. Hasan Sadikin General Hospital Bandung between July 2017 and December 2020. The patients were categorized into two groups based on their access type: proximal and distal. The incidence of long-term RAO was evaluated through Doppler ultrasound at least one-year post-TRA. Results: The study included 107 patients (proximal = 72 patients; distal = 35 patients). The mean age was 58.2 ± 8.26 years, with a predominance of male patients (79.4%) and smokers (65.4%). The majority of procedures were interventional (58.2%). Baseline characteristics were comparable between the two groups, except for selecting the access side, which was more prevalent on the left side in the distal group. Long-term RAO occurred in 8 patients (7.48%), with 7 cases (9.72%) in the proximal group and 1 case (2.86%) in the distal group (p=0.269). Conclusion: The study findings reveal no significant difference in the incidence of long-term RAO between proximal and distal radial access in invasive cardiovascular procedures.
HUBUNGAN ANTARA DIABETES MELITUS TIPE 2 DAN SKOR LESI KALSIFIKASI BERDASARKAN PEMERIKSAAN INTRAVASCULAR ULTRASOUND (IVUS) PADA PASIEN PENYAKIT ARTERI KORONER Saboe, Aninka; Wahyudi, Dendi Pudji; Fattima, Eliza Techa; Yahya, Achmad Fauzi
Jurnal Kardiologi Indonesia Online First
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1449

Abstract

Background: Coronary artery calcification reflects the chronic burden of atherosclerosis and contributes to procedural complexity during Percutaneous Coronary Intervention (PCI). While coronary calcium has been extensively studied using Computed Tomography (CT), data on Intravascular Ultrasound (IVUS)-derived calcium characteristics in Southeast Asian populations remain limited. The Southeast Asian population, particularly Indonesians, may exhibit distinct patterns of atherosclerosis influenced by genetic, lifestyle, and metabolic factors. Therefore, we sought to investigate the association between cardiovascular risk factors and IVUS-derived total coronary calcium score in an Indonesian population. Methods: This single-center, retrospective observational study included consecutive patients who underwent IVUS-guided PCI between January 2020 and December 2021. Data on patient demographics and cardiovascular risk factors were obtained from medical records. The IVUS calcium scores recorded in the database were independently reanalyzed and validated by an experienced interventional cardiologist to ensure consistency and accuracy. Associations between cardiovascular risk factors and total IVUS calcium score were assessed using Spearman's rank correlation and the Kruskal–Wallis test.Results: A total of 111 patients were included in this study with a mean age of 61.3 ± 10.2 years; 72.1% were male. Hypertension was present in 60.4%, DM in 45.0%, dyslipidemia in 38.7%, and active smoking in 40.5%. The mean IVUS total calcium score was 1.93 ± 1.41. Among individual risk factors, dyslipidemia (ρ = 0.22, p = 0.021) and smoking (ρ = −0.24, p = 0.009) were significantly associated with calcium score. Patients with ≥2 risk factors had higher mean calcium scores (2.15 ± 1.35) compared with those with ≤1 risk factor (1.15 ± 1.33; p = 0.028). Conclusion: The total IVUS calcium score correlated significantly with the presence of dyslipidemia in this Indonesian population. A cumulative increase in cardiovascular risk factors was associated with greater coronary calcium burden, suggesting that multifactorial risk exposure plays an important role in coronary calcification in this population.
Co-Authors Augustine Purnomowati Badai Bhatara Tiksnadi Dewi, Triwedya Indra Eliza Techa Fattima, Eliza Techa Hadiyatussalamah Pusfa Kencanasari, Hadiyatussalamah Pusfa Ibrahim, Maulana Muhammad Rizki Akbar, Muhammad Rizki Pranata, Raymond Saboe, Aninka Setiawan Setiawan Syarief Hidayat Toni Mustahsani Aprami, Toni Mustahsani Wahyudi, Dendi Pudji