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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya ARTERI : Jurnal Ilmu Kesehatan
Annisa Hanifwati
Universitas Muhammadiyah Malang
Electrical & Electronics Engineering Health Professions Medicine & Pharmacology Nursing Public Health

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Peran Karotenoid Sebagai Pencegahan Degenerasi Makula Aryani Vindhya Putri; Nabila Nurmalina; Alfa Sylvestris; Annisa Hanifwati
ARTERI : Jurnal Ilmu Kesehatan Vol 4 No 1 (2022): November
Publisher : Puslitbang Sinergis Asa Professional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/arteri.v4i1.243

Abstract

Macular degeneration or often called Age-related Macular Degeneration (AMD) is a degenerative disease that attacks the center of vision in the retina, namely the macula. In an effort to prevent the progression of AMD, consuming antioxidants has been shown to inhibit the AMD development process. Although currently there is no definite number of AMD sufferers in Indonesia, it is estimated that the number of AMD sufferers will continue to increase. Carotenoids are one of the antioxidant compounds that have been shown to inhibit the development of macular degeneration. Carotenoids are divided into several classes, one of which is the xanthophyll class. Lutein and zeaxanthin compounds belong to the xanthophyll class. The content of lutein and zeaxanthin in body plasma has been shown to reduce the risk of macular diseases such as AMD. This study aims to determine the role of carotenoids as the prevention of macular degeneration. The method used is a literature review in the form of a narrative review. Search literature in the form of journals and textbooks through Google Scholar, PubMed, Science Direct, and Research Gate, indexed by Scopus, ISSN, national journals and international journals. The journals used were published in the last 5 years and books published in the last 10 years. The results of the analysis show that carotenoid antioxidants are proven to be able to act as a prevention of AMD by reducing oxidative stress. Carotenoids will quench free radicals, thereby preventing the occurrence of lipid peroxidation, and preventing the formation of AMD. Carotenoids also prevent damage mediated by exposure to blue light. Consumption of lutein and zeaxanthin can also reduce the expression of VEGF (vascular endothelial growth factor) in the retina so that it can inhibit the increase of VEGF. It can be concluded that carotenoid antioxidants can prevent the progression of macular degeneration.
Hubungan Usia, Massa Lemak, dan Indeks Massa Tubuh dengan Nyeri Punggung Bawah pada Karyawan Rumah Sakit Umum Universitas Muhammadiyah Malang Anung Putri Illahika; Annisa Hanifwati; Risma Karlina Prabawati; Muh. Rizal Hidayat; Amatullah Rusydah Aqiilah; Deny Dwi Julianti; Nielanawalul Putri Rosyanti
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 10 No 01 (2026): Qanun Medika Vol 10 No 01 January 2026
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v10i01.26159

Abstract

Low back pain (LBP) is a leading cause of global disability, significantly impacting work productivity. Known risk factors include age and obesity. However, while Body Mass Index (BMI) is a common indicator of obesity, BMI provides limited insight into true body composition. This study used Bioelectrical Impedance Analysis (BIA) to provide a more precise measurement of fat mass and to analyze its correlation with LBP, along with age and BMI, among employees at the University of Muhammadiyah Malang (UMM) General Hospital. The study used a cross-sectional design involving 112 hospital employees. Age was collected through a questionnaire. Fat mass was measured using the Tanita BC-418, and LBP was assessed using the Nordic Body Map (NBM) questionnaire, which distinguishes between complaints and disabilities. Statistical analysis used the Kruskal-Wallis test for correlations involving LBP complaints (age and fat mass) and the Spearman correlation test for correlations involving LBP disabilities (age and BMI). This study found no statistically significant correlations between the analyzed variables and LBP complaints or disabilities. Spearman's correlation test showed a weak, insignificant relationship between age and LBP disability (r=0.141; p=0.130) and between BMI and LBP disability (r=0.148; p=0.116). Similarly, the Kruskal-Wallis test did not show a significant correlation between age and LBP complaints (p=0.299) or between fat mass and LBP complaints (p=0.564). Conclusion: Age, fat mass, and BMI were not found to be significant predictors of LBP complaints or disability in this specific hospital employee population. These findings suggest that occupational or ergonomic factors may play a more dominant role in the etiology of LBP in hospital staff than anthropometric parameters alone.
Co-Authors Alfa Sylvestris Amatullah Rusydah Aqiilah Anung Putri Illahika Aryani Vindhya Putri Deny Dwi Julianti Muh. Rizal Hidayat Nabila Nurmalina Nielanawalul Putri Rosyanti Risma Karlina Prabawati