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PENGARUH EKSTRAK DAUN KERSEN (MUNTINGIA CALABRA L.) TERHADAP PROFIL LIPID MENCIT PUTIH (MUS MUSCULUS) JANTAN YANG DIINDUKSI MINYAK JELANTAH Puspasari, Anita Fitri; Agustini, Sulistyo Mulyo; Illahika, Anung Putri
Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol 12, No 1 (2016): JUNI 2016
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1972.554 KB) | DOI: 10.22219/sm.v12i1.5260

Abstract

ABSTRAK Hiperlipidemia merupakan salah satu faktor resiko penyakit jantung koroner dan stroke. Hal tersebut dapat diketahui dengan hasil profil lipid. Saat ini, pencegahan hiperlipidemia dapat dilakukan dengan cara alami yang disebut fitofarmaka. Salah satunya yaitu ekstrak daun kersen mengandung flavonoid, saponin, dan tannin yang dapat memperbaiki profil lipid dalam darah. Tujuan penelitian ini adalah mengetahui adakah pengaruh ekstrak daun kersen (Muntinga calabura l.) terhadap perbaikan kadar profil lipid mencit hyperlipidemia. Metode penelitian adalah True experimental dengan post test only control group design dengan kontrol negatif, kontrol positif, 3 perlakuan yang diinduksi minyak jelantah sebagai hiperlipidemia dan ekstrak daun kersen untuk perbaikan profil lipid dosis 1.5,3,6 (mg/200gBB/hari). Data dianalisis menggunakan uji normalitas, uji homogenitas, uji ANOVA, uji post hoc, uji regresi yang pengolahannya menggunakan SPSS 19.Hasil Uji One Way Anova pada variabel p=0,000 (p<0,05) terdapat perbedaan signifikan. Hasil uji post hoc didapatkan perbedaan bermakna (p<0,05) antar kelompok. Pada Uji regresi linier didapatkan dosis terbaik pada dosis 6 (mg/200gBB/hari) dengan presentaseperbaikan kolesterol total 65%, TG 79%, LDL 79%, dan HDL 75%. Flavonoid menghambat sintesis kolesterol dengan menghambat HMG-KoA reduktase. Saponin dan Tannin bekerja dengan menghambat penyerapan kolesterol dan trigliserida di usus. Kesimpulannya adalah ekstrak daun kersen berpengaruh terhadap perbaikan kadar profil lipid mencit putih hiperlipidemiaKata kunci : Hiperlipidemia, ekstrak daun kersen
PENGARUH EKSTRAK DAUN KERSEN (MUNTINGIA CALABRA L.) TERHADAP PROFIL LIPID MENCIT PUTIH (MUS MUSCULUS) JANTAN YANG DIINDUKSI MINYAK JELANTAH Anita Fitri Puspasari; Sulistyo Mulyo Agustini; Anung Putri Illahika
Saintika Medika Vol. 12 No. 1 (2016): JUNI 2016
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.v12i1.5260

Abstract

ABSTRAK Hiperlipidemia merupakan salah satu faktor resiko penyakit jantung koroner dan stroke. Hal tersebut dapat diketahui dengan hasil profil lipid. Saat ini, pencegahan hiperlipidemia dapat dilakukan dengan cara alami yang disebut fitofarmaka. Salah satunya yaitu ekstrak daun kersen mengandung flavonoid, saponin, dan tannin yang dapat memperbaiki profil lipid dalam darah. Tujuan penelitian ini adalah mengetahui adakah pengaruh ekstrak daun kersen (Muntinga calabura l.) terhadap perbaikan kadar profil lipid mencit hyperlipidemia. Metode penelitian adalah True experimental dengan post test only control group design dengan kontrol negatif, kontrol positif, 3 perlakuan yang diinduksi minyak jelantah sebagai hiperlipidemia dan ekstrak daun kersen untuk perbaikan profil lipid dosis 1.5,3,6 (mg/200gBB/hari). Data dianalisis menggunakan uji normalitas, uji homogenitas, uji ANOVA, uji post hoc, uji regresi yang pengolahannya menggunakan SPSS 19.Hasil Uji One Way Anova pada variabel p=0,000 (p<0,05) terdapat perbedaan signifikan. Hasil uji post hoc didapatkan perbedaan bermakna (p<0,05) antar kelompok. Pada Uji regresi linier didapatkan dosis terbaik pada dosis 6 (mg/200gBB/hari) dengan presentaseperbaikan kolesterol total 65%, TG 79%, LDL 79%, dan HDL 75%. Flavonoid menghambat sintesis kolesterol dengan menghambat HMG-KoA reduktase. Saponin dan Tannin bekerja dengan menghambat penyerapan kolesterol dan trigliserida di usus. Kesimpulannya adalah ekstrak daun kersen berpengaruh terhadap perbaikan kadar profil lipid mencit putih hiperlipidemiaKata kunci : Hiperlipidemia, ekstrak daun kersen
The Effect Of Family Support On Stress Level In Muhammadiyah High School 1 Malang Students With Acne Vulgaris Dwi Nurwulan Pravitasari; Anung Putri Illahika; Dian Yuliartha lestari; Febriana Nur Layli; Siska Fitriana
Saintika Medika Vol. 17 No. 2 (2021): December 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM2.18001

Abstract

Adolescence is a stage that has relatively not reached maturity both emotionally and mentally so that in achieving good development, it is necessary to have positive support in life from the family. Stress that occurs identified as one of the triggering factors for acne vulgaris. To determine the effect of family support on stress levels in Muhammadiyah High School 1 Malang students with acne vulgaris complaints. This research an analytic observational study with a cross-sectional approach. Sampling by purposive sampling and a sample of 52 respondents. Analyzed with Spearman correlation followed by ordinal regression analysis. The results of the ordinal regression test of the effect of family support on stress levels showed a value of p = 0.000 (p<0.05), which means that there is an effect of family support on the stress level of students who have acne vulgaris complaints, with the magnitude of the OR being exp (3.323) = 27.743. The magnitude of the influence of family support in predicting the stress level of students with acne vulgaris complaints is 46.7% There is an effect of family support on stress levels in students of Muhammadiyah High School 1 Malang with acne vulgaris complaints.
Effects of acupressure therapy period towards blood sugar level in type 2 diabetes mellitus patients at Lumajang acupressure clinic Anung Putri Illahika; Hean Safira
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.5097

Abstract

Abstract  Diabetes Mellitus is a worldwide metabolic disease and becomes a challenge for the health practitioner. Unfortunately, less than half of these diabetic individuals are aware of their conditions, and less than 1% of those receiving medical treatment achieve their therapeutic targets. Acupressure is an alternative method that is believed to be an effective way of treating diabetic patients with reducing symptoms and complications. This research aims to discover the effect of period acupressure therapy on blood sugar levels in type two diabetes mellitus patients in Lumajang Acupressure Clinic. It uses an observational analytic design with pre-test and post-test approach. It involved 36 participants who were split into two groups and contained 18 participants for each group. The first group received acupressure therapy for three weeks, while the second group received eight weeks. Both groups underwent acupressure at the San Yin Jiao (SP-6) acupoint for 20 minutes three times a week. All participants in both groups had their blood glucose checked before and after acupressure therapy. The results showed that the two groups were significantly different for the paired t-test and the independent t-test. The acupressure therapy period has an effect on decreasing blood sugar levels in type two diabetes mellitus patients at Lumajang acupressure clinic. Keywords             : Acupressure, the period of therapy, blood glucose level, type two diabetes mellitusCorrespondence   : Anungputri113@gmail.com
Analysis of the relationship between using personal protective equipment (PPE) masks on the incidence of respiratory symptoms disorders of online motorcycle taxis drivers in Malang Jeremi Setiawan; Hanna Cakrawati; Anung Putri Illahika
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 1 (2022): Journal Qanun Medika Vol 6 No 01
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i1.10267

Abstract

ABSTRACT  Health problems that are often encountered due to work are respiratory disorders that cause premature death every year. Exposure to pollution is harmful to health, and chronic exposure causes lung cancer and COPD. The use of masks is an alternative in reducing exposure to pollution. This study aimed to determine the relationship between the habit of wearing masks on the incidence of respiratory symptoms disorder of online motorcycle taxi drivers in Malang. This study was an analytic observation with a cross-sectional design. Samples were determined using the comparative bivariate analytical sample formula. The data were analyzed using a univariate test and bivariate analysis with a chi-square test. This study showed a significant relationship between the habit of wearing a mask with p score = 0.015 (p<0,05), changing time with p score = 0.004 (p<0,05), and the type of mask on respiratory symptoms disorders with p score = 0.006 (p<0,05). The results obtained regarding the description of the habit of using masks, the results of the method of using masks were mainly in the good category. In conclusion, there is a significant relationship between the habit of wearing masks and the incidence of respiratory symptoms disorders among online motorcycle taxi drivers in Malang. Keywords             : Habits, masks, symptoms of respiratory disorders, online motorcycle taxisCorrespondence   : Jeremisetiawan@webmail.umm.ac.id
Efek Ekstrak Bunga Melati (Jasminum Sambac) dengan Metode Elektrik terhadap Efek Knockdown pada Nyamuk Aedes Aegypti Stadium Dewasa Rizky Noni Amalia; Anung Putri Illahika; Aida Musyarrofah; Fathiyah Safithri
Jurnal Kesehatan Islam : Islamic Health Journal Vol 11, No 1 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i1.16078

Abstract

Abstract. Dengue Hemorrhagic Fever (DHF) is caused by the Dengue virus (DENV) which is transmitted by mosquitoes. One of the factors that cause high number of dengue infections in Indonesia is due to poor vector management. Chemical-based insecticides used to control mosquitos can cause human health problems and mosquito resistance. Jasmine flower (Jasminum sambac) can be used as an alternative because it contains flavonoids, alkaloids, saponins, and tannins that can act as natural insecticides. Objective: Proving the effect of jasmine flower extract (Jasminum sambac) with the electric method has a knockdown effect on adult stage Aedes aegypti mosquitoes. Method: True Experimental Post Test Only Control Group Design. In each test group, 20 adult Aedes aegypti were used with four replications. In this study, the test group consisted of malathion as positive control, aquades as negative control, and jasmine flower extract (Jasminum sambac) at concentrations of 5%, 10%, 15%, 20%, and 25%. Data was analyzed using Kruskal Wallis test, Post Hoc Mann Whitney test, Spearman correlation test and Probit test. Results and Discussion: Kruskal Wallis test obtained a significance value (P) <0.05. Post hoc mann whitney test showed knockdown effect at concentrations of 15%, 20% and 25%. The results of the Spearman correlation test (P = 0.019 and R = 0.440) showed a sufficient correlation between the con­centration of jasmine flower extract and the knockdown effect. LC50 was obtained by probit test at a concentration of 12.839%. The results showed that the content of jasmine flower extract had an insecticidal effect with the electric method. Conclusion: Jasmine flower extract (Jasminum sambac) applied using the electric method has a knockdown effect on adult Aedes aegypti at concentrations of 15%, 20% and 25%.
Mortality and morbidity of pregnant woman with COVID- 19 Infection : A meta analysis Aida Musyarrofah; Anung Putri Illahika; Probo Yudha Pratama Putra; Dinda Amalia Eka Putri; S.Khansa Zatalini; Yohanes Eddy Prasetyo
International Journal of Public Health Science (IJPHS) Vol 11, No 4: December 2022
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v11i4.21769

Abstract

Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2 and declared as a global pandemic in March 2020. There is a special immune tolerance in pregnant woman, predisposes to a viral infection, then increased risk severe complication. A comprehensive literature study was performed in July 2021 through Science Direct, Cochrane, and PubMed, with keywords “COVID-19”, “SARS-CoV-2”, “Pregnancy”, “Pregnant”, and “Complication”. Nine studies with 30.257 infected patients and 1.678.974 non infected patients were included. The data show that preterm birth (OR=1.43, 95% CI: 1.17-1.74; p = 0.0004, I2=90%) less in non infected groups, no camparable finding in vaginal delivery (OR =0.93, 95% CI: 0.82-1.06; p<0.030, I2=75%) and caesarian delivery (OR =1.07, 95% CI: 0.90-1.28; p<0.045, I2=96%). ICU admission reported high percentage in infected patients (OR =4.87, 95% CI: 3.08-7.71; p<0.0001, I2=93%), we found that obstetric complication in subgroup (OR =1.31, 95% CI: 0.13-1.52; p<0.0003,I2=54%) and mortality (OR =17.41, 95% CI: 11.04-27.46; p<0.0001, I2=0%) less in non infected patients. Pregnancy with infected COVID-19 has high percentage of mortality and morbidity events. Infected and non infected patients has equal chance for vaginal or caesarian delivery.
Kajian Literatur: Hubungan Tingkat Pengetahuan Kesehatan dan Keselamatan Kerja (K3) dengan Kejadian Kecelakaan Kerja Delly Safira Hedaputri; Rubayat Indradi; Anung Putri Illahika
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 1 No. 3 (2021): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.432 KB) | DOI: 10.37148/comphijournal.v1i3.27

Abstract

Introduction: The trend of work accidents increased and gave various impacts ranging from countable losses or direct costs to uncountable losses or indirect costs, makes it a topic that never stops being discussed. This high incidence of work accidents can be caused by three factors, there are: human, work, and the work environment. The level of Occupational Health and Safety (OHS) knowledge, which is included in the human factor is an important point in building a healthy, safe, not polluted work environment, and free of work accidents in order to increase the productivity and efficiency of workers and able to reduce the incidence of work accidents. Objective: This paper aims to know the correlation between the level of OHS knowledge and work accidents. Method: This paper is a quantitative study of kinds of literature. Bibliography like articles and literature books were obtained through several search engines, there are 2 from Google, 10 from Google Books, 17 from Google Scholar, 4 from PubMed, 6 from NCBI, 4 from Science Direct, and 1 from BMC. Criteria for national journals accredited by Sinta (S3-S5) and international journals accredited by Scopus (Q2) and non-Scopus with the longest the publication year of 2015. Results and Discussion: The result of this assessment shows that level of OHS knowledge associated with the incidence of work accidents in which the higher level of OHS knowledge on workers in a workplace would be the lower incidence of work accidents. Conclusion: There is a relationship between the level of OHS knowledge and work accidents. Further research is needed about matters that affect the level of OHS knowledge and other variables that affect work accidents and the relationships in particular sectors.
Analisis Korelasi Lipatan Kulit (TLK) Dengan Indeks Massa Tubuh (IMT) Remaja Perempuan Madura Di Sumenep Anung Putri Illahika
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 6, No 1 (2019): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.634 KB) | DOI: 10.26714/magnamed.6.1.2019.65-68

Abstract

Analysis of Skinfold Correlation (TLK) with Body Mass Index (BMI) of Madurese Adolescent Girls in SumenepBackground: Growth and development is a continuous process in the process of reaching adulthood, including the adolescent stage. The problem that is often faced is physical changes. The physical changes in adolescent girls that are very visible are the increase in height and weight that affect Body Mass Index (BMI). One of the body compositions that can be measured is Skinfold Thickness (TLK), which is part of body fat mass. The difference in location allows for differences in TLK among individuals even though they are of the same ethnicity.Objective: This study was to determine the relationship between TLK and Body Mass Index (BMI) of female Madurese ethnicity in Sumenep.Methods: This research is a correlation study and takes a sample of 40 high school students who are in the range of 17-20 years, namely students of SMA Negeri 1 Sumenep. TLK was measured left on the biceps, triceps, subscapular and suprailiac. BMI is an index obtained from the results of dividing BB by TB. The measurement results are expressed in kg/m22. All data obtained will be analyzed using the Spearmen correlation test.Results: The results of the analysis showed that there was a relationship between body mass index and skinfold thickness. The significance value of extremity TLK is 0.002 with a large correlation of 0.485. The significance value of TLK truncus is 0.042 with a large correlation of -0.323. This means that the higher the BMI, the lower the TLK of the extremities.Conclusion: There is a relationship between body mass index and skinfold thickness of Madurese girls in Sumenep.Latar belakang: Tumbuh kembang merupakan proses yang berkesinambungan dalam proses mencapai dewasa, termasuk tahap remaja. Permasalahan yang sering dihadapi adalah peruubhan fisik. Perubahan fisik remaja perempuan yang sangat tampak adalah meningkatnya tinggi dan berat badan yang mempengaruhi Indeks Massa Tubuh (IMT). Salah satu komposisi tubuh yang dapat diukur adalah Tebal Lipatan Kulit (TLK), yang merupakan bagian dari massa lemak tubuh. Perbedaan lokasi memungkinkan adanya perbedaan TLK pada individu meskipun etnis yang sama. Tujuan: Penelitian untuk mengetahui hubungan TLK dengan Indeks Massa Tubuh (IMT) remaja perempuan etnis Madura di Sumenep. Metode: Penelitian ini merupakan studi korelasi dan mengambil sampel dari siswa SMA berjumlah 40 memiliki di kisaran 17-20 tahun yaitu siswi SMA Negeri 1 Sumenep. TLK diukur di bagian sinistra pada biceps, triceps, subscapula dan suprailiaca. IMT adalah suatu indeks yang didapatkan dari hasil pembagian BB dengan TB. Hasil pengukuran dinyatakan dalam kg/m22.Semua data yang diperoleh akan dianalisis menggunakan uji korelasi spearmen.Hasil: Hasil analisis menunjukkan terdapat hubungan antara indeks massa tubuh dengan tebal lipatan kulit. Nilai signifikansi TLK ekstremitas adalah 0,002 dengan besar korelasi 0,485. Nilai signifikansi TLK trunkus adalah 0,042 dengan besar korelasi -0,323. Artinya semakin tinggi IMT maka semakin menurun TLK Extremitas.Simpulan: Terdapat hubungan antara indeks massa tubuh dengan tebal lipatan kulit remaja perempuan Madura di Sumenep.
Review Artikel: Pengaruh Diet Semangka Merah (Citrullus lanatus) terhadap VO2Max Annisa Hanifwati; Ajeng Salsabilla Pawestri; Hanna Cakrawati; Anung Putri Illahika
ARTERI : Jurnal Ilmu Kesehatan Vol 4 No 1 (2022): November
Publisher : Puslitbang Sinergis Asa Professional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/arteri.v4i1.253

Abstract

Technological rapidly developments influence in lifestyle changes of people who do sedentary lifestyles. Lack of physical activity can reduce the value of VO2max, so that will impact on lowering physical fitness index. Value of VO2max can be increased through consumption of red watermelon (Citrullus lanatus) that is contained citrulline. Red watermelon is the richest source of citrulline compared to other fruits or vegetable on cucurbitaceae plants. Substance of citrulline that enters the body is converted to nitric oxide (NO) which can increase VO2max through the mechanism of oxidative phosphorylation in mitochondria. This study is to know the effect of red watermelon (Citrullus lanatus) to VO2max. This paper is a qualitative study of literature. Bibliography like articles and literature books were obtained through the Elsevier, PubMed, Cochrane Library, and Google Scholar search engines. The result of analysis shows that the consumption of red watermelon (Citrullus lanatus) affects of VO2max enhancement. Nutrients of citrulline, which is contained in red watermelon, increases NO bioavailability and has an effect on increasing VO2max. In conclusion consumption of red watermelon juice (Citrullus lanatus) affects to value of VO2max.