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Cytotoxic Activity and Phytochemical Analysis of Breynia cernua from Papua Dirgantara, Septriyanto; Tanjung, Rosye H.R.; Maury, Hendra K.; Meiyanto, Edy
Indonesian Journal of Pharmaceutical Science and Technology Suppl 1, No. 1 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.159 KB) | DOI: 10.15416/ijpst.v1i1.16121

Abstract

Breynia cernua (local name Katuk Hutan) is an Indonesian medicinal plant (family: Euphorbiace- ae) originated from Papua which have been used traditionally as alternative treatment for breast and cervical cancer. The objectives of this research were to investigate potential cytotoxic activity and phytochemical aspect test of B. cernua extract and its fractions. Extraction was performed by macera- tion using ethanol 96%, followed by successive fractionations. Phytochemical screening and in vitro cytotoxic activity test were obtained for extract and active fraction with Brine Shrimp Lethality Test (BSLT) method and MCF-7 tumor cell lines were assessed by 3-(4-5-dimethylthiazol-2yl)-2,5-diphe- nyl tetrazolium bromide (MTT) assay. The results from cytotoxic activity test of breast cancer MCF-7 cell line from ethanolic 96% extract and three fractions: n-hexane, ethylacetate and water fractions showed 246.841 ppm, 165.65 ppm, 562.57 ppm dan 713.78 ppm respectively meanwhile the IC50 value of doxorubicin as the positive control was 6 μM. TLC and phytochemical screening showed the pres- ence of alkaloids, terpenoid, avonoids and tannins compounds in this active plant. Keywords: Antitumor, Breynia cernua, BSLT, MCF-7
Cytotoxic Activity and Phytochemical Analysis of Breynia cernua from Papua Septriyanto Dirgantara; Rosye H.R. Tanjung; Hendra K. Maury; Edy Meiyanto
Indonesian Journal of Pharmaceutical Science and Technology Suppl 1, No. 1 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.159 KB) | DOI: 10.24198/ijpst.v1i1.16121

Abstract

Breynia cernua (local name Katuk Hutan) is an Indonesian medicinal plant (family: Euphorbiace- ae) originated from Papua which have been used traditionally as alternative treatment for breast and cervical cancer. The objectives of this research were to investigate potential cytotoxic activity and phytochemical aspect test of B. cernua extract and its fractions. Extraction was performed by macera- tion using ethanol 96%, followed by successive fractionations. Phytochemical screening and in vitro cytotoxic activity test were obtained for extract and active fraction with Brine Shrimp Lethality Test (BSLT) method and MCF-7 tumor cell lines were assessed by 3-(4-5-dimethylthiazol-2yl)-2,5-diphe- nyl tetrazolium bromide (MTT) assay. The results from cytotoxic activity test of breast cancer MCF-7 cell line from ethanolic 96% extract and three fractions: n-hexane, ethylacetate and water fractions showed 246.841 ppm, 165.65 ppm, 562.57 ppm dan 713.78 ppm respectively meanwhile the IC50 value of doxorubicin as the positive control was 6 μM. TLC and phytochemical screening showed the pres- ence of alkaloids, terpenoid, avonoids and tannins compounds in this active plant. Keywords: Antitumor, Breynia cernua, BSLT, MCF-7
Kajian Kualitas Air Laut dan Indeks Pencemaran Berdasarkan Parameter Fisika-Kimia di Perairan Distrik Depapre, Jayapura Baigo Hamuna; Rosye H.R. Tanjung; Suwito Suwito; Hendra Kurniawan Maury; Alianto Alianto
Jurnal Ilmu Lingkungan Vol 16, No 1 (2018): April 2018
Publisher : School of Postgraduate Studies, Diponegoro Univer

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (224.41 KB) | DOI: 10.14710/jil.16.1.35-43

Abstract

ABSTRAKKondisi kualitas air suatu perairan yang baik sangat penting untuk mendukung kelulushidupan organisme yang hidup di dalamnya. Penentuan status mutu air perlu dilakukan sebagai acuan dalam melakukan pemantauan pencemaran kualitas air. Penelitian ini bertujuan untuk mengkaji status mutu air dan menentukan indeks pencemaran berdasarkan parameter fisika-kimia di perairan Distrik Depapre, Kabupaten Jayapura. Pengambilan sampel kualitas air dilakukan pada bulan Oktober 2017 di lima stasiun penelitian, kemudian hasilnya dibandingkan dengan baku mutu air laut untuk biota laut berdasarkan KEPMEN-LH No. 51 Tahun 2004. Hasil penelitian menunjukkan bahwa parameter yang masih sesuai baku mutu antara lain suhu, salinitas, sulfida dan kecerahan perairan, sedangkan parameter yang telah melampaui baku mutu antara lain pH, ammonia total, nitrat dan fosfat. Berdasarkan hasil perhitungan indeks pencemaran menunjukkan bahwa perairan Distrik Depapre berada dalam kategori tercemar ringan hingga tercemar sedang.Kata kunci: Baku Mutu, Indeks Pencemaran, Kualitas Air, Parameter Fisika-Kimia, Distrik DepapreABSTRACTGood water quality is extremely important to support life of organisms. The determination of water quality status was needed as reference to monitor water pollution. This study aimed to assess the status of water quality and determine pollution index based on physical-chemical parameters in the Depapre District waters, Jayapura Regency. Sampling was carried out in October 2017 across five research stations, then the results were compared with water quality standards based on KEPMEN-LH No. 51 Tahun 2004 for marine biotas. The results showed that the parameters in according to the quality standards are temperature, salinity, sulphide and water transparency, while those that have exceeded the quality standards are pH, total ammonia, nitrate and phosphate. Based on the calculation of pollution index indicates that the Depapre District waters was in light pollution to medium categories.Keywords: Depapre District, Physical-Chemical Parameters, Pollution Index, Standards, Water QualityCitation: Hamuna, B., Tanjung, R.H.R, Suwito, Maury H.K. dan Alianto (2018).Kajian Kualitas Air Laut dan Indeks Pencemaran Berdasarkan Parameter Fisika-Kimia Di Perairan Distrik Depapre, Jayapura. Jurnal Ilmu Lingkungan, 16(1), 35-43, doi:10.14710/jil.16.135-43
KONSENTRASI AMONIAK, NITRAT DAN FOSFAT DI PERAIRAN DISTRIK DEPAPRE, KABUPATEN JAYAPURA Baigo Hamuna; Rosye H. R. Tanjung; Suwito Suwito; Hendra Kurniawan Maury
EnviroScienteae Vol 14, No 1 (2018): EnviroScienteae Volume 14 Nomor 1, April 2018
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/es.v14i1.4887

Abstract

The determination of water quality status was needed as a reference to monitor water pollution. The purpose of this study was to determine the concentration of ammonia, nitrate, and phosphate in Depapre waters, Jayapura Regency. Sampling was carried out in October 2017 across five research stations, then the results were compared with water quality standards based on KEPMEN-LH No. 51 Tahun 2004 for marine biotas. Based on the analysis of water quality in Depapre waters obtained the following results are the ammonia content ranges from 0.8 to 11.6 mg/L, the content of nitrate ranged from 0.009 to 0.54 mg/L, and the phosphate content ranged from 0.016 to 1.19 mg/L. These results indicate that the ammonia, nitrate and phosphate concentration in Depapre Waters have exceeded the water quality standard. The concentration of ammonia, nitrate, and phosphate is high enough and endanger the lives of marine biotas.
Valuasi Ekonomi Kawasan Birdwatching Repang Muaif Marsi Adi Purwadi; Hendra Kurniawan Maury
The Community Engagement Journal Vol 2, No 1 (2019)
Publisher : UNIVERSITAS CENDERAWASIH

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (200.552 KB) | DOI: 10.52062/.v2i1.2150

Abstract

The objectives of the activities of the Economic Evaluation of the Repang Muaif Birdwatching Area in Jayapura Regency are to: 1) Increase the knowledge and understanding of the community about the functions and roles of the Repang Muaif Birdwatching Zone in Jayapura Regency; 2) The creation of an equal role of the community in the development of the Repang Muaif Birdwatching Area in Jayapura Regency. The area to be carried out in the study area is the Economic Valuation of the Repang Muaif Birdwatching Area in Jayapura Regency. Where the results of the implementation of science and technology are from the results of the pree test conducted, it was found that out of 21 participants who attended this training, 76.19 percent of participants did not understand the concepts and rules regarding the economic valuation of forest ecosystems. While the rest, which is as much as 23.81 percent, have known the concepts and rules related to the economic valuation of forest ecosystems. Whereas from the post test results, it was found that out of 21 participants who attended this training, 15.08 percent of the participants still did not understand the concepts and rules regarding the economic valuation of forest ecosystems. While the rest, which is as much as 84.92 percent have known the concepts and rules related to the economic valuation of forest ecosystems. In addition, the participation of the community in forest conservation is very important, it can be seen from the many participants who want to attend this training activity. Where of the 25 participants planned as participants in this training, 21 participants attended the training and 4 participants did not take part in the training.
Pemantauan Kualitas Air Sungai Digoel, Distrik Jair, Kabupaten Boven Digoel, Papua Rosye H.R. Tanjung; Hendra K. Maury; Suwito Suwito
Jurnal Biologi Papua Vol 8, No 1 (2016)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (378.707 KB) | DOI: 10.31957/jbp.43

Abstract

Digoel river have an important role to the human activity and environment in Boven Digoel Regency. Increasing of human and industrial activity around the watershed of Digoel River were suspecious to cause the degradation water quality in Digoel River. This research was done to monitor the impact of the industrial activity to the quality of water in outlet of waste water treatment plant(WWTP) of PT. Korindo to the water quality of Digoel River. Parameter analised are the physical, chemical, organic chemical, microbiology and metal content in water. Analysis of the water quality accordance to PP Nomor 82 Tahun 2001 about water quality managementand water pollution and Permen LH Nomor 5 tahun 2014 about the quality of waste water.The monitoring was conducted in three months at five sampling stasion (river upstream, river down stream, outlet WWTP plywood, outlet WWT workshop, outlet WWTP palm oil) in Districk Jair. The rsult showed, parameter of BOD, COD, phospate, phenol and total coliform in Digoel River exceeded class I of water quality standards. Outlet of plywood WWTP have two parameters that exceed the quality standard which were TSS 15.67 mg/L and phenol 13.33 mg/L.The outlet of WWTP workshop have four pameter exceeded the quality standard which were TSS (383.67 mg/L), oil/fats (502.0 µg/L), phenol (11.0 µg/L), and zinc (21,000 mg/L). IPAL oil WWTP outlet have two parameter sexceeded the quality standars which were oil/fats (313.0 µg/L) and total coliform (> 979 cells/100 mL). The result indicating  that the status of water quality of Digoel River are categorized as “lightly polluted”. Therefore based on utilization, it was categorized as class IV water quality that can be used for irrigating, planting and other purposed that meet the requairement of water qualiy in this class, while for other uses need necessary processing. In order  not to  increase the pollution in the Digoel river the WWTP of industry around Digoel River should improved their treatment, so that waste water discharged to the Digoel River not exceed the stanards quality.Key words: water quality, digoel river, status of water quality, pollutant index.
Keanekaragaman Ngengat Superfamily Bombicoidea: Eksplorasi Potensi Ulat Sutera di Dataran Rendah Kabupaten Jayapura Hendra K. Maury; Marsi A. Purwadi; Euniche R.P.F. Ramandey; John R. Bisai; Bruce H.R. Mauri
Jurnal Biologi Papua Vol 14, No 2 (2022)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.747 KB) | DOI: 10.31957/jbp.2352

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Jayapura Regency is one of the regions that considerable potential for economic growth from non-timber forest products. In the development of non-timber forest products in the form of products produced by insects, silk yarn is one of the commodity that has a high demand. The domestic demand for silk yarn is 900 tons/year, while only 19.05 tons/year were produced in 2012. Jayapura Regency has a great potential to supply the shortage of cocoon for the domestic market and the wide open international market. Related to this challenge, this study conducted basic research on the diversity of moths from the Bombicoidea superfamily in the natural forest of Kampung Soaib, Jayapura Regency. Sampling using light traps, four species of moths from the Saturnidae family were obtained, Syntherata apicalis, Opodiphtera intermedia, Opodiphtera papuana, and Coscinocera hercules. The cocoon of Coscinocera hercules is very potential as a silk thread producer because it is large and consists of two layers with brown color and has fiber characteristics similar to the cocoon of Attacus atlas which has been developed as a wild silk producer. These results indicate that the lowland forests of Jayapura Regency as a habitat for wild silkworm species has potential to be developed as non-timber forest products.Key words: Superfamily Bombicoidea; silkworm; cocoon; Jayapura regency
Pendugaan Densitas Karbon Pada Tegakan Pohon di Kawasan Hutan Kampung Sawesuma, Distrik Unurum Guay, Kabupaten Jayapura Ziyadatun Ni'mah; Rosye H.R. Tanjung; Hendra K. Maury
Jurnal Biologi Papua Vol 14, No 1 (2022)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.414 KB) | DOI: 10.31957/jbp.2110

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The community managed conservation area forest (AKKM) of Kampung Sawesuma is part of the lowland forest landscape of Northern Papua. Lowland forests have a very high diversity of plant species and act as carbon sinks stored in tree stands. To determine the amount of carbon stored in tree stands, an estimation of the carbon density of tree stands was carried out in the AKKM forest area of Kampung Sawesuma, Jayapura. Estimation of carbon density was carried out by non-destructive method of tree stands using sample plots (measurement transects) and calculating tree biomass using allometric equations. The measurement results show that the tree biomass in the AKKM forest area is 167.5 tons/ha with an estimated carbon density of 78.7 tons/ha in the stands. Key words: carbon density; lowland forest; Sawesuma Village.
Analisis Dimorfisme Kupu-Kupu Sayap Burung (Ornithoptera sp.) Endemik Papua Evie L. Warikar; Euniche R.P.F. Ramandey; Hendra K. Maury
Jurnal Biologi Papua Vol 11, No 1 (2019)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2001.735 KB) | DOI: 10.31957/jbp.634

Abstract

Ornitophera sp. is one of the groups of butterflies endemic in Papua and West Papua provinces. The significant morphological differences between male and female butterflies (dimorphism) are in the shape, size and color of the wings. Morphological characteristics are important sources of information. Based on the results of specimen collections at the Papua Insect Collection Laboratory (KSP) Jayapura, there are several species from various locations in Papua. The variation in dimorphism is likely to occur in this species which gives rise to new sub-species. The purpose of this study was to record the dimorphism of the endemic Bird Wing of Papua which had been stored in the Papua Insect Collection Laboratory (KSP) Jayapura. The method used is a direct measurement of the morphology of bird wing butterfly specimens stored in the KSP Laboratory, Cenderawasih University. Morphometric data were analyzed using the SPSS 20 and Multi Variate Statistical Package (MVSP 3.1) programs. The results obtained were 7 Ornithoptera species stored in the KSP Jayapura Laboratory, namely O. chiamera, O. goliath, O. meridionalis, O. paradisea, O. priamus, O. thitonus and O. rothschildi. Based on observations there are striking differences in color, shape and size between male and female in the same species.   Key words: birdwing butterfly, Ornithoptera sp., KSP Jayapura, dimorphisme.  
Pendugaan Cadangan Karbon Pada Tegakan Pohon di Kawasan Hutan Lindung Irier (HLI) Kampung Sewan, Distrik Sarmi Timur Kabupaten Sarmi, Papua Sammaria J. Karma; Rosye H.R. Tanjung; Hendra K. Maury
Jurnal Biologi Papua Vol 13, No 2 (2021)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (502.474 KB) | DOI: 10.31957/jbp.1739

Abstract

Irier Protection Forest in Sewan Village has an area of 750 ha which is included in the Sarmi Lintas Mamberamo Raya KPHP area. This study aims to determine carbon stock value of the forest vegetation. The method to determine the location of the study using purposive sampling with line transect  method to determine the density of vegetation. Furthermore, the method of calculation of the carbon stocks stored calculated using allometric equations. The results showed that the Irier Village Protected Forest Area has 21 trees belonging to 14 families with a total of 343 trees/ha. The value of biomass is 170.61 tons/ha and value of carbon stocks stored in timber stands is 80.18 tons/ha.  Key words: Carbon stocks; Irier village protected forest; Sewan; vegetation